[CAS NO. 123-99-9]  Azelaic acid

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PRODUCTS SPECIFICATIONS [123-99-9]

Catalog
HY-B0704
Brand
MCE
CAS
123-99-9

DESCRIPTION [123-99-9]

Overview

MDLMFCD00004432
Molecular Weight188.22
Molecular FormulaC9H16O4
SMILESOC(CCCCCCCC(O)=O)=O

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE


Summary

Azelaic acid is an organic compound produced by the ozonolysis of oleic acid; component of a number of hair and skin conditioners.


Clinical Trial

NCT Number Sponsor Condition Start Date Phase
NCT03094403 Taro Pharmaceuticals USA
Rosacea
July 1, 2016 Phase 1
NCT02120924 Actavis Inc.
Rosacea
July 2013 Phase 3
NCT00617903 LEO Pharma|Bayer
Papulopustular Rosacea
January 2008 Phase 2

Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL ( 531.29 mM )

H 2 O : 2 mg/mL ( 10.63 mM ; Need ultrasonic)

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.3129 mL 26.5647 mL 53.1293 mL
5 mM 1.0626 mL 5.3129 mL 10.6259 mL
10 mM 0.5313 mL 2.6565 mL 5.3129 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (13.28 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (13.28 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (13.28 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

Nonanedioic acid
Azelaic acid
Anchoic acid
1,7-Heptanedicarboxylic acid
Lepargylic acid
Emerox 1144
1,9-Nonanedioic acid
1,7-Dicarboxyheptane
n-Nonanedioic acid
Emery 1110
ZK 62498
Skinoren
Empol 1144
NSC 19493
Finacea
Emery 1144
Azelic acid
α,ω-Nonanedioic acid
Aziderm