[CAS NO. 1239602-35-7]  Antibacterial agent 18

Ships within Stock Price Qty Total
$0.00
$0.00
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [1239602-35-7]

Catalog
HY-W074648
Brand
MCE
CAS
1239602-35-7

DESCRIPTION [1239602-35-7]

Overview

MDL-
Molecular Weight605.63
Molecular FormulaC39H27NO6
SMILESO=C(C1=CC=C(C2=CC=C(N(C3=CC=C(C4=CC=C(C(O)=O)C=C4)C=C3)C5=CC=C(C6=CC=C(C(O)=O)C=C6)C=C5)C=C2)C=C1)O

For research use only. We do not sell to patients.

Summary

Antibacterial agent 18 is a multi-arm AIE molecule extracted from patent CN110123801A, compound 23. Antibacterial agent 18 can be used for resisting Gram-positive and Gram-negative bacteria. Antibacterial agent 18 can be conjugated in the cell wall of rigid arm configuration insertion bacterium, and block cell wall turns sugar and turns peptide process, to inhibit or kill bacterium [1] .


In Vitro

Antibacterial agent 18 (0.004-4 μg/mL; 24 h) inhibits the growth of Gram-positive and Gram-negative bacteria, with MICs ranging from 0.008-1 μg/mL [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL ( 41.28 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6512 mL 8.2559 mL 16.5117 mL
5 mM 0.3302 mL 1.6512 mL 3.3023 mL
10 mM 0.1651 mL 0.8256 mL 1.6512 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: 2.5 mg/mL (4.13 mM); Suspended solution; Need ultrasonic

* All of the co-solvents are available by MCE.


Synonyms

[1,1′-Biphenyl]-4-carboxylic acid, 4′,4′′′,4′′′′′-nitrilotris-
4′,4′′′,4′′′′′-Nitrilotris[[1,1′-biphenyl]-4-carboxylic acid]
4′,4′′′,4′′′′′-Nitrilotris[1,1′-biphenyl]-4-carboxylic acid