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Catalog: | HY-W401531S |
Brand: | MCE |
CAS: | 1259947-39-1 |
MDL | - |
---|---|
Molecular Weight | 214.23 |
Molecular Formula | C10H10D3NO4 |
SMILES | OC([C@H](N)CC1=CC(OC([2H])([2H])[2H])=C(C=C1)O)=O |
(R)-3-O-Methyldopa-d 3 is a deuterium labeled (R)-3-O-Methyldopa, and (R)-3-O-Methyldopa is an R-enantiomer of 3-O-Methyldopa. 3-O-Methyldopa is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of L-DOPA and dopamine[1][2].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Room temperature in continental US; may vary elsewhere.
Please store the product under the recommended conditions in the Certificate of Analysis.
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