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[CAS NO. 1295541-87-5] SCD1inhibitor-4
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-141525 |
| Brand: | MCE |
| CAS: | 1295541-87-5 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 363.34 |
| Molecular Formula | C17H16F3N5O |
| SMILES | O=C(C1=C(C)N(CC2=CC=CC(C(F)(F)F)=C2)C=N1)NC3=NN(C)C=C3 |
Summary
SCD1 inhibitor-4 is a potent, orally active stearoylCoA desaturase-1 ( SCD1 ) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes [1] .
IC50 & Target
SCD1 [1]
In Vivo
SCD1 inhibitor-4 (1~30 mg/kg) shows a dose-dependent decrease in desaturation index with a 55 % reduction at 1 mg/kg and 85% reduction at the 10 and 30 mg/kg doses [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 275.22 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.7522 mL | 13.7612 mL | 27.5224 mL |
| 5 mM | 0.5504 mL | 2.7522 mL | 5.5045 mL |
| 10 mM | 0.2752 mL | 1.3761 mL | 2.7522 mL |
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