[CAS NO. 131-69-1] Phthalylsulfacetamide

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PRODUCTS SPECIFICATIONS [131-69-1]

Catalog

HY-B0967

Brand

MCE

CAS

131-69-1

DESCRIPTION [131-69-1]

Overview

MDL	MFCD00020275
Molecular Weight	362.36
Molecular Formula	C16H14N2O6S
SMILES	O=C(O)C1=CC=CC=C1C(NC2=CC=C(S(=O)(NC(C)=O)=O)C=C2)=O

For research use only. We do not sell to patients.

Summary

Phthalylsulfacetamide is a sulfa drug, after oral administration, slowly decompose in the intestine,and release sulfacetamide ,generating antibacterial effect.

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL ( 68.99 mM ; Need ultrasonic)

H ₂ O : 1 mg/mL ( 2.76 mM ; ultrasonic and warming and heat to 80°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7597 mL	13.7984 mL	27.5969 mL
5 mM	0.5519 mL	2.7597 mL	5.5194 mL
10 mM	0.2760 mL	1.3798 mL	2.7597 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (6.90 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (6.90 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (6.90 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Keagy PM, et al. Rat bioassay of wheat bran folate and effects of intestinal bacteria. J Nutr. 1989 Dec;119(12):1932-9.

Synonyms

Benzoic acid, 2-[[[4-[(acetylamino)sulfonyl]phenyl]amino]carbonyl]-

Phthalanilic acid, 4′-(acetylsulfamoyl)-

2-[[[4-[(Acetylamino)sulfonyl]phenyl]amino]carbonyl]benzoic acid

4′-(Acetylsulfamoyl)phthalanilic acid

4′-(Acetylsulfamyl)phthalanilic acid

Enterocid

Enterosulfamid

Ftalicetimida

Enterosulfon

Phthaloylsulfacetamide

Phthalylsulfacetamide

Rabalan

Sterathal

Talecid

Talicetimida

Talsutin

Tamid

Thalisul

Thalocid

TSC-80 Medicated

TSC-80

Thalajen

Talasulfa

Kalacet

Sulphalyl

NSC 163977T

Talsigel

NSC 163977

NSC 4368

2-((4-(N-Acetylsulfamoyl)phenyl)carbamoyl)benzoic acid