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[CAS NO. 1316059-00-3] GSK854
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-119608 |
| Brand: | MCE |
| CAS: | 1316059-00-3 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 482.96 |
| Molecular Formula | C18H19ClN6O4S2 |
| SMILES | O=S(C1=CC=C(C(NC2=NC=NC(NC3=NC=C(C=C3)Cl)=C2)=C1)S(=O)(CC)=O)(NC)=O |
Summary
GSK854 is a potent Inhibitor of Troponin I-Interacting Kinase ( TNNI3K ). GSK854 is a suitable lead for identifying new cardiac medicines and have been employed as in vivo tools in investigational studies aimed at defining the role of TNNI3K within heart failure [1] .
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 250 mg/mL ( 517.64 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.0706 mL | 10.3528 mL | 20.7056 mL |
| 5 mM | 0.4141 mL | 2.0706 mL | 4.1411 mL |
| 10 mM | 0.2071 mL | 1.0353 mL | 2.0706 mL |
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1.
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2.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.08 mg/mL (4.31 mM); Clear solution
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