[CAS NO. 1402931-70-7]  eIF4A3-IN-11

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PRODUCTS SPECIFICATIONS [1402931-70-7]

Catalog
HY-148445
Brand
MCE
CAS
1402931-70-7

DESCRIPTION [1402931-70-7]

Overview

MDL-
Molecular Weight520.53
Molecular FormulaC29H28O9
SMILESCOC1=CC=C([C@@]23OC4=CC(C(OC)=O)=CC(OC)=C4[C@]2(O)[C@@H]([C@@H]([C@H]3C5=CC=CC=C5)C(OC)=O)O)C=C1

For research use only. We do not sell to patients.

Summary

eIF4A3-IN-11 (compound 56) is a silvestrol (HY-13251) analogue. eIF4A3-IN-11 interferes the assembling of eIF4F translation complex with EC 50 s of 0.2, 4 and 0.3 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-11 can be used for the research of human cancer pathogenesis [1] .


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Please store the product under the recommended conditions in the Certificate of Analysis.