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[CAS NO. 1429321-13-0] TA-316
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-112486 |
| Brand: | MCE |
| CAS: | 1429321-13-0 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 641.56 |
| Molecular Formula | C28H25BrN4O5S2 |
| SMILES | O=C(C1=CC=C(C(NCC2=CC=C(C(NCCO)=O)C=C2)=O)S1)N/N=C(C3=CSC(C4=CC=C(Br)C=C4)=C3O)\C |
Summary
In Vitro
TA-316 (0.01-1000 nM; 4 days) stimulates UT-7/TPO and Ba/F3-HuMpl cells proliferation, with the EC
50
values of 0.3 and 0.65 nM, respectively
[2]
.
TA-316 (800 nM; 10 days) promotes biased megakaryopoiesis and upregulated MK lineage markers
[2]
.
TA-316 (200 nM; 4 days) preferentially enhances VEGFA and FGF2 expression
[2]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Cell Viability Assay [2]
| Cell Line: | UT-7/TPO and Ba/F3-HuMpl cells |
| Concentration: | 0.01-1000 nM |
| Incubation Time: | 4 days |
| Result: | Stimulated UT-7/TPO and Ba/F3-HuMpl cell proliferation. |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 50 mg/mL ( 77.94 mM ; ultrasonic and warming and heat to 60°C)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.5587 mL | 7.7935 mL | 15.5870 mL |
| 5 mM | 0.3117 mL | 1.5587 mL | 3.1174 mL |
| 10 mM | 0.1559 mL | 0.7794 mL | 1.5587 mL |
References
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