[CAS NO. 146669-29-6] (RS)-MCPG
PRODUCTS SPECIFICATIONS [146669-29-6]
DESCRIPTION [146669-29-6]
Overview
| MDL | MFCD00210205 |
|---|---|
| Molecular Weight | 209.20 |
| Molecular Formula | C10H11NO4 |
| SMILES | CC(C(O)=O)(N)C1=CC=C(C(O)=O)C=C1 |
1 Publications Citing Use of MCE
Summary
IC50 & Target
group I/group II mGluR [1]
In Vitro
MCPG can block group I (mGluR1 and mGluR5) and group II receptors (mGluR2 and mGluR3) [2] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
(RS)-MCPG (alpha-MCPG; 500 μM) blocks the TBS-induced shifts in EGABA in either juvenile or neonatal neurons
[1]
.
Pretreatment with the low dose of (RS)-MCPG (25 nM; i.c.; daily; 5 days) significantly attenuates amphetamine-induced locomotor activity in 10-day-old male and female rats of Sprague-Dawley descent
[2]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
1M NaOH : 100 mg/mL ( 478.01 mM ; ultrasonic and adjust pH to 10 with NaOH)
DMSO : 6 mg/mL ( 28.68 mM ; Need ultrasonic and warming)
H 2 O : < 0.1 mg/mL (ultrasonic;heat to 80°C) (insoluble)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 4.7801 mL | 23.9006 mL | 47.8011 mL |
| 5 mM | 0.9560 mL | 4.7801 mL | 9.5602 mL |
| 10 mM | 0.4780 mL | 2.3901 mL | 4.7801 mL |
References