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[CAS NO. 147821-57-6] Niazinin
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-N8471 |
| Brand: | MCE |
| CAS: | 147821-57-6 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 343.40 |
| Molecular Formula | C15H21NO6S |
| SMILES | O[C@H]([C@@H]([C@H]([C@@H](O1)C)O)O)[C@@H]1OC2=CC=C(C=C2)CNC(OC)=S |
Summary
In Vitro
Niazinin, is cytotoxic at substantially higher concentration (CC50 of 31.6 µM) than its antileishmanial concentration (IC50 of 5.25 µM) [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : ≥ 50 mg/mL ( 145.60 mM )
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.9121 mL | 14.5603 mL | 29.1206 mL |
| 5 mM | 0.5824 mL | 2.9121 mL | 5.8241 mL |
| 10 mM | 0.2912 mL | 1.4560 mL | 2.9121 mL |
-
1.
-
2.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: 2.5 mg/mL (7.28 mM); Clear solution; Need ultrasonic
References
- [1] Amandeep Kaur, et al. Antileishmanial compounds from Moringa oleifera Lam. Z Naturforsch C J Biosci. Mar-Apr 2014;69(3-4):110-6.
- [2] Shiv Rakesh Naik, et al. Structure-based virtual screening, molecular dynamics and binding affinity calculations of some potential phytocompounds against SARS-CoV-2. J Biomol Struct Dyn. 2021 Mar 8;1-18.
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