[CAS NO. 148757-94-2] AQC
PRODUCTS SPECIFICATIONS [148757-94-2]
DESCRIPTION [148757-94-2]
Overview
| MDL | MFCD01940654 |
|---|---|
| Molecular Weight | 285.25 |
| Molecular Formula | C14H11N3O4 |
| SMILES | O=C(ON1C(CCC1=O)=O)NC2=CC=C3N=CC=CC3=C2 |
1 Publications Citing Use of MCE
Summary
AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent used for amino acid or protein sequence analysis by HPLC with fluorescence detection. AQC reacts with primary and secondary amino acids to yield fluorescent derivates, allowing amino acid detection at under-picomolar levels [1] [2] .
In Vitro
The use of AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate), which reacts with primary and secondary amino acids to yield fluorescent derivates (λ excitation and emission at 250 and 395 nm, respectively), allowing amino acid detection at under-picomolar levels, overcomes many of the drawbacks associated with the rest of derivatising reagents [1] [2] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 350.57 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.5057 mL | 17.5285 mL | 35.0570 mL |
| 5 mM | 0.7011 mL | 3.5057 mL | 7.0114 mL |
| 10 mM | 0.3506 mL | 1.7528 mL | 3.5057 mL |
References
- [1] Bosch L, et al. Application of the 6-aminoquinolyl-N-hydroxysccinimidyl carbamate (AQC) reagent to the RP-HPLC determination of amino acids in infant foods. J Chromatogr B Analyt Technol Biomed Life Sci. 2006;831(1-2):176-183.
- [2] Cohen SA, et al. Applications of amino acid derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate. Analysis of feed grains, intravenous solutions and glycoproteins. J Chromatogr A. 1994;661(1-2):25-34.
Synonyms