[CAS NO. 1504558-72-8] Nec-3a
PRODUCTS SPECIFICATIONS [1504558-72-8]
DESCRIPTION [1504558-72-8]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 438.37 |
| Molecular Formula | C21H18F4N2O4 |
| SMILES | COC1=CC=C2CC[C@H]3[C@@H](C4=CC=C(C(F)=C4)OC(F)(F)F)N(C(CO)=O)N=C3C2=C1 |
Summary
Nec-3a is a Necrostatin-3 analogue. Nec-3a is a RIP1 inhibitor ( IC 50 : 0.44 μM). Nec-3a inhibits the autophosphorylation activity of the RIP1 kinase domain [1] .
IC50 & Target
|
RIPK1 0.44 μM (IC 50 ) |
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.