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[CAS NO. 154361-50-9] Capecitabine

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Catalog:	HY-B0016
Brand:	MCE
CAS:	154361-50-9

Overview

MDL	MFCD00930626
Molecular Weight	359.35
Molecular Formula	C15H22FN3O6
SMILES	O[C@H]1[C@@H](O)[C@H](N2C=C(C(NC(OCCCCC)=O)=NC2=O)F)O[C@@H]1C

For research use only. We do not sell to patients.

11 Publications Citing Use of MCE

[1]Cancer Lett. 2020 Apr 28;476:67-74.
[2]J Adv Res. 12 June 2021.
[3]Acta Pharmacol Sin. 2021 Jan;42(1):108-114.
[4]Front Oncol. 2021 Jul 13;11:704042.
[5]J Mol Med (Berl). 2019 Aug;97(8):1183-1193.
[6]Cancer Cell Int. 2023 Jan 31;23(1):14.
[7]Cell Death Discov. 2022 May 2;8(1):238.
[8]Biochem Eng J. 2022: 108722.
[9]In Vitro Cell Dev Biol Anim. 2021 May 5.
[10]Open Life Sci. 2023, 18(1).
[11]Research Square Preprint. 2022 Feb.

Summary

Capecitabine is an oral prodrug that is converted to its active metabolite, 5-FU, by thymidine phosphorylase.

IC50 & Target

DNA/RNA Synthesis ^[1]

In Vitro

Capecitabine is an anti-cancer chemotherapy drug. It is classified as an antimetabolite. Capecitabine is converted into 5′-deoxy-5-fluorocytidine (5′DFCR), 5′-deoxy-5-fluorouridine (5′DFUR) and 5-FU by carboxylesterases (CES1 and 2), cytidine deaminase (CDD), and thymidine phosphorylase (TP), in both liver and tumour. Capecitabine induces a significant cytotoxic effect in vitro only at high concentrations. Mean IC ₅₀ values vary from 860 μM in COLO205 cells to 6000 μM in HCT8 cells ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

A pharmacokinetic/pharmacodynamic study is carried out in mice bearing HCT 116 xenografts receiving 0.52 and 2.1 mmol/kg/d of Capecitabine by oral gavage. Capecitabine administered at 0.52 mmol/kg/day induces partial control of HCT 116 xenografts tumour growth: growth rate =7.5±0.5 on day 21. Capecitabine 2.1 mmol/kg/day achieves complete control of tumor growth during the treatment period: growth rate =1±0.2 on day 21 ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase
NCT03428529	Instituto Nacional de Cancer, Brazil	Rectal Neoplasm Malignant	January 12, 2011	Phase 2\|Phase 3
NCT00496704	Yonsei University\|National Cancer Institute (NCI)	Colorectal Cancer	January 2007	Phase 1\|Phase 2
NCT02560974	Hoffmann-La Roche	Gastric Cancer	June 2006	Phase 3
NCT03997968	Cyteir Therapeutics, Inc.	Malignancy\|Non-hodgkin Lymphoma\|Multiple Myeloma\|Breast Cancer\|Ovarian Cancer\|Soft Tissue Sarcoma\|Head and Neck Cancer\|DLBCL\|Mantle Cell Lymphoma\|Follicular Lymphoma\|Pancreatic Cancer\|CLL\|Small Cell Lung Cancer\|Squamous Cell Carcinoma of Head and Neck\|Triple Negative Breast Cancer	October 9, 2019	Phase 1\|Phase 2
NCT00706069	Hellenic Oncology Research Group\|University Hospital of Crete	Metastatic Breast Cancer	June 2008	Phase 1
NCT04556773	AstraZeneca\|Daiichi Sankyo Co., Ltd.\|Daiichi Sankyo Company, Limited	Metastatic Breast Cancer	December 17, 2020	Phase 1
NCT00354523	M.D. Anderson Cancer Center\|Novartis Pharmaceuticals	Solid Tumor\|Thyroid Cancer	December 2004	Phase 1\|Phase 2
NCT05536102	Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine	Gastric Cancer	September 5, 2022	Phase 2
NCT02415829	Fudan University	Colorectal Cancer	November 2014	Phase 2
NCT00148135	University of Michigan Rogel Cancer Center\|Eli Lilly and Company	Carcinoma of Unknown Primary	May 2001	Phase 2
NCT04156698	Eye & ENT Hospital of Fudan University	Hypopharyngeal Carcinoma\|Immunotherapy\|Chemotherapy	May 21, 2020	Phase 2
NCT00962312	Cancer Trials Ireland	Pancreatic Cancer	January 2009	Phase 2
NCT04103697	Blokhin´s Russian Cancer Research Center	Rectal Neoplasms Malignant\|Rectum Carcinoma\|Rectal Cancer	August 1, 2019	Phase 3
NCT02068131	The Affiliated Hospital of the Chinese Academy of Military Medical Sciences	Metastatic Colorectal Cancer	February 2014	Phase 2
NCT01525082	Shaheen Shagufta\|National Cancer Institute (NCI)\|Stanford University	Gastrinoma\|Glucagonoma\|Insulinoma\|Pancreatic Polypeptide Tumor\|Recurrent Islet Cell Carcinoma\|Recurrent Pancreatic Cancer\|Somatostatinoma\|Stage III Pancreatic Cancer\|Stage IV Pancreatic Cancer	December 2012	Phase 2
NCT02664103	Sanofi	Breast Cancer Metastatic	January 23, 2016	Phase 2
NCT02344472	Prof. W. Janni\|Roche Pharma AG\|Novartis Pharmaceuticals\|Eisai GmbH\|Celgene Corporation\|University of Ulm	Metastatic Breast Cancer	September 2015	Phase 3
NCT02289547	The Catholic University of Korea	Stomach Neoplasms	May 2015	Phase 3
NCT00578071	Brian Czito\|Amgen\|Duke University	Cancer of the Esophagus	December 2007	Phase 1\|Phase 2
NCT02592746	Samsung Medical Center	Metastatic Breast Cancer	June 2016	Phase 2
NCT04856761	Fudan University	Biliary Tract Neoplasms\|Recurrence\|Cholangiocarcinoma\|Gall Bladder Cancer	November 1, 2020
NCT01969032	Russian Academy of Medical Sciences	Triple Negative Breast Cancer	August 2011	Phase 2
NCT00006023	Swiss Group for Clinical Cancer Research	Prostate Cancer	March 2000	Phase 2
NCT01024504	Hellenic Oncology Research Group\|University Hospital of Crete	Metastatic Colorectal Cancer	March 2006	Phase 2
NCT03117972	Centre Hospitalier Universitaire de Besancon	Metastatic Colorectal Cancer	August 4, 2017	Phase 2
NCT00454636	Hoffmann-La Roche	Gastric Cancer	March 2007	Phase 2
NCT00665457	University of Nebraska\|National Cancer Institute (NCI)	Breast Cancer	April 2004	Phase 2
NCT02595320	Qamar Khan\|University of Kansas Medical Center	Breast Cancer\|Gastrointestinal Cancer	October 5, 2015	Phase 2
NCT05104866	AstraZeneca\|Daiichi Sankyo, Inc.	Breast Cancer	October 18, 2021	Phase 3
NCT02394535	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Borderline Resectable Pancreatic Adenocarcinoma\|Locally Advanced Pancreatic Adenocarcinoma\|Pancreatic Adenocarcinoma\|Stage II Pancreatic Cancer AJCC v6 and v7\|Stage IIA Pancreatic Cancer AJCC v6 and v7\|Stage IIB Pancreatic Cancer AJCC v6 and v7\|Stage III Pancreatic Cancer AJCC v6 and v7	November 12, 2015	Phase 1
NCT00469443	Hellenic Oncology Research Group\|University Hospital of Crete	Colorectal Cancer	December 2006	Phase 3
NCT03376659	Georgetown University\|Mayo Clinic\|Indiana University\|Emory University\|National Cancer Institute (NCI)\|George Mason University\|Thomas Jefferson University\|MedImmune LLC\|Bavarian Nordic	Metastatic Colorectal Cancer\|Colorectal Adenocarcinoma\|Pancreatic Adenocarcinoma\|Metastatic Pancreatic Cancer	August 8, 2018	Phase 1\|Phase 2
NCT03588533	Sung Yong Oh\|Celltrion\|Dong-A University Hospital	HER-2 Positive Gastric Cancer\|Metastatic Cancer	June 10, 2018	Phase 2
NCT03503136	Sun Yat-sen University\|Tongji Hospital\|Wuhan Union Hospital, China\|Peking University\|Air Force Military Medical University, China\|Second Affiliated Hospital of Soochow University\|The First Affiliated Hospital of Guangdong Pharmaceutical University\|First People´s Hospital of Foshan\|Fifth Affiliated Hospital, Sun Yat-Sen University\|Cancer Hospital of Guizhou Province\|Xiangya Hospital of Central South University\|Jilin Provincial Tumor Hospital\|Henan Cancer Hospital\|Hunan Cancer Hospital\|Cancer Hospital of Guangxi Medical University\|Affiliated Cancer Hospital & Institute of Guangzhou Medical University\|Zhejiang Cancer Hospital	Nasopharyngeal Carcinoma	June 2018	Phase 3
NCT00429871	Hellenic Oncology Research Group\|University Hospital of Crete	Breast Cancer	May 2002	Phase 3
NCT01130337	Hoffmann-La Roche	Gastric Cancer	July 2010	Phase 2
NCT02002195	International Group of Endovascular Oncology	Metastatic Gastric Cancer	November 2013
NCT02210364	PharmaMar	Metastatic Breast Cancer\|Pancreatic Cancer\|Metastatic Colorectal Cancer	April 2013	Phase 1
NCT02598349	Proton Collaborative Group\|University of Florida Health	Pancreatic Cancer	April 2016	Phase 2
NCT04309578	Asan Medical Center	Gastric or Gastroesophageal Junction(GEJ) Adenocarcinoma	March 12, 2020	Phase 2
NCT00303745	Federation Francophone de Cancerologie Digestive\|National Cancer Institute (NCI)	Colorectal Cancer	June 2006	Phase 2
NCT03578874	The University of Hong Kong	Hepatocellular Carcinoma	June 20, 2016	Phase 2
NCT01126138	Cancer Institute and Hospital, Chinese Academy of Medical Sciences\|Hoffmann-La Roche	Carcinoma, Invasive Ductal, Breast	July 2010	Phase 3
NCT02485834	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Adenocarcinoma of the Gastroesophageal Junction\|Gastric Adenocarcinoma\|Gastric Cancer	August 2015	Phase 2
NCT00398320	Pamela L. Kunz\|Stanford University	Neuroendocrine Tumors	November 2006	Phase 2
NCT00216437	James A. Haley Veterans Administration Hospital\|Hoffmann-La Roche	Cancer of Liver	December 2004	Phase 1
NCT04379596	AstraZeneca\|Daiichi Sankyo Company, Limited 3-5-1 Nihonbashihoncho, Chuo-ku, Tokyo	Gastric Cancer	June 3, 2020	Phase 2
NCT03563157	ImmunityBio, Inc.	Colorectal Cancer Metastatic\|mCRC	May 25, 2018	Phase 1\|Phase 2
NCT00677443	Samsung Medical Center\|National Cancer Center, Korea\|Seoul National University Bundang Hospital\|Seoul National University Hospital\|Gachon University Gil Medical Center\|Yonsei University\|Asan Medical Center\|Chonnam National University Hospital	Colorectal Cancer	June 2008	Phase 3
NCT00964704	Hoffmann-La Roche	Breast Cancer	March 2011	Phase 2
NCT01415336	Peking Union Medical College Hospital	Breast Cancer	March 2010	Phase 2\|Phase 3
NCT01993472	Gu Yanhong\|The First Affiliated Hospital with Nanjing Medical University	Colorectal Neoplasms	November 2013	Phase 2
NCT04188158	Universidad de León	Locally Advanced Colon Cancer	March 10, 2017	Phase 2
NCT00052273	Jonsson Comprehensive Cancer Center\|Eli Lilly and Company	Adult\|Solid Tumor	December 2002	Phase 1
NCT03779035	Tianjin Medical University Cancer Institute and Hospital	Cholangiocarcinoma\|Gall Bladder Carcinoma	December 15, 2018	Phase 3
NCT01374425	Genentech, Inc.	Colorectal Cancer	August 2011	Phase 2
NCT03156036	Asan Medical Center	Advanced Rectal Cancer	November 30, 2017	Phase 2
NCT00368329	Stanford University	Esophageal Neoplasms\|Carcinoma, Squamous Cell\|Adenocarcinoma\|Esophageal Cancer	June 2006	Phase 1
NCT00253565	Herbert Hurwitz\|National Cancer Institute (NCI)\|Duke University	Unspecified Adult Solid Tumor, Protocol Specific	August 2003	Phase 1
NCT01917552	Asan Medical Center\|Ulsan University Hospital\|Seoul National University Bundang Hospital\|Gangnam Severance Hospital\|Seoul National University Boramae Hospital\|Ajou University School of Medicine\|Chung-Ang University Hosptial, Chung-Ang University College of Medicine\|Hallym University Medical Center\|Inje University\|Kyung Hee University Hospital\|Gachon University Gil Medical Center\|Kangbuk Samsung Hospital\|Korea University Guro Hospital\|Kyungpook National University Hospital	Gastric Cancer	November 2013	Phase 3
NCT03084939	Hoffmann-La Roche	Breast Cancer	April 24, 2017	Phase 3
NCT01262469	UNICANCER\|GlaxoSmithKline	Metastatic Breast Cancer\|70 Years Old Patients and Over\|After One Line of Chemotherapy With Trastuzumab	December 2009	Phase 2
NCT00477464	GlaxoSmithKline	Metastatic Breast Cancer\|Neoplasms, Breast	June 2007	Phase 2
NCT01099527	Samsung Medical Center	Metastatic Gastric Cancer	October 2009	Phase 1\|Phase 2
NCT01043484	Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)\|Hoffmann-La Roche	Rectal Cancer	December 2009	Phase 2
NCT03329248	ImmunityBio, Inc.	Pancreatic Cancer	November 6, 2017	Phase 1\|Phase 2
NCT03986385	Hebei Medical University	Gastroesophageal Junction Adenocarcinoma	June 1, 2019	Phase 3
NCT03415763	LI XIN-XIANG\|Fudan University	Rectal Neoplasms	November 5, 2018	Phase 3
NCT01503983	Fundación para el Progreso de la Oncología en Cantabria	Stage IV Gastric Cancer With Metastasis	August 2011	Phase 2
NCT00503932	M.D. Anderson Cancer Center	Rectal Cancer	July 2007	Phase 1\|Phase 2
NCT03585465	Centre Oscar Lambret\|Anticancer Fund, Belgium\|Bristol-Myers Squibb\|CTD-CNO\|ECS-Progastrin SA	Childhood Solid Tumor	March 26, 2019	Phase 1\|Phase 2
NCT00290615	Herbert Hurwitz\|National Cancer Institute (NCI)\|Duke University	Colorectal Cancer	January 2006	Phase 2
NCT04177602	Universitätsklinikum Hamburg-Eppendorf\|Clinical Trial Center North (CTC North GmbH & Co. KG)\|Servier Affaires Médicales	Locally Advanced Rectal Cancer	November 4, 2019	Phase 1\|Phase 2
NCT03387098	ImmunityBio, Inc.	Pancreatic Cancer	January 2, 2018	Phase 1\|Phase 2
NCT00182715	Velindre NHS Trust\|National Cancer Institute (NCI)	Colorectal Cancer	March 2005	Phase 3
NCT05111444	Fudan University	Gastric Neoplasms\|Gastroesophageal Junction Adenocarcinoma	December 31, 2021	Phase 2
NCT02007148	International Group of Endovascular Oncology	Gastric Adenocarcinoma\|Gastroesophageal Junction Adenocarcinoma	November 2013	Phase 2
NCT02720601	New Mexico Cancer Care Alliance	Biliary Tract Cancer	November 2015	Phase 2
NCT03691051	Henan Cancer Hospital	HER2 Positive Metastatic Breast Cancer	November 20, 2018	Phase 2
NCT01664494	Hoffmann-La Roche	Breast Cancer, Colorectal Cancer, Gastric Cancer	April 2010
NCT01167738	IRCCS San Raffaele	Pancreatic Cancer	July 2010	Phase 2
NCT01208103	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Ampulla of Vater Adenocarcinoma\|Small Intestinal Adenocarcinoma\|Stage III Ampulla of Vater Cancer AJCC v8\|Stage III Small Intestinal Adenocarcinoma AJCC v8\|Stage IIIA Ampulla of Vater Cancer AJCC v8\|Stage IIIA Small Intestinal Adenocarcinoma AJCC v8\|Stage IIIB Ampulla of Vater Cancer AJCC v8\|Stage IIIB Small Intestinal Adenocarcinoma AJCC v8\|Stage IV Ampulla of Vater Cancer AJCC v8\|Stage IV Small Intestinal Adenocarcinoma AJCC v8	May 6, 2011	Phase 2
NCT00925769	Hoffmann-La Roche	Pancreatic Cancer	January 2009	Phase 1
NCT00347438	University of Chicago\|Breast Cancer Research Foundation\|Roche Pharma AG	Breast Cancer	September 2006	Phase 2
NCT00087152	National Cancer Institute (NCI)	Breast Cancer	June 2004	Phase 2
NCT05239169	Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest	Biliary Tract Cancer (CCA)\|Intrahepatic Cholangiocarcinoma\|Hilar Cholangiocarcinoma\|Distal Cholangiocarcinoma\|Gall Bladder Carcinoma	May 23, 2022	Phase 2
NCT03009058	Immodulon Therapeutics Ltd	Metastatic Cancer	May 24, 2017	Phase 1\|Phase 2
NCT04304352	European Institute of Oncology	Advanced Breast Cancer	July 29, 2011	Phase 2
NCT01097265	Jeroen Bosch Ziekenhuis\|National Cancer Institute (NCI)	Colorectal Cancer	July 2010	Phase 2\|Phase 3
NCT01782651	GlaxoSmithKline	Neoplasms, Breast	August 2014
NCT05291052	The First Affiliated Hospital with Nanjing Medical University	Biliary Tract Tumor	February 14, 2022	Phase 2
NCT04509596	Dizal Pharmaceuticals	Breast Cancer Metastatic	September 21, 2020	Phase 1
NCT00230399	University of Michigan Rogel Cancer Center	Colorectal Cancer	June 2003	Phase 2
NCT00629148	Fudan University	Breast Cancer\|Metastasis, Neoplasm	August 2007	Phase 2
NCT01953003	Pierre Fabre Medicament	Malignant Neoplasm of Breast	September 2013	Phase 3
NCT04165772	Memorial Sloan Kettering Cancer Center\|Tesaro, Inc.	Rectal Adenocarcinoma\|Clinical Stage: Stage II (T3-4, N-)\|Stage III (Any T, N&addition;)\|Solid Tumor\|Solid Tumor, Adult	December 11, 2019	Phase 2
NCT00193609	SCRI Development Innovations, LLC\|Roche Pharma AG\|Sanofi-Synthelabo	Neoplasms, Unknown Primary	September 2004	Phase 2
NCT02910843	Swiss Group for Clinical Cancer Research	Rectal Cancer	February 22, 2017	Phase 1
NCT02514681	Japan Breast Cancer Research Group\|Chugai Pharmaceutical	HER2-positive Locally Advanced or Metastatic Breast Cancer	August 1, 2015	Phase 3
NCT00711412	Northwestern University	Esophageal Cancer	May 31, 2006	Phase 2
NCT00632489	SCRI Development Innovations, LLC\|Novartis	Breast Cancer	May 2008	Phase 1
NCT00305643	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)\|Pfizer	Breast Cancer\|Colorectal Cancer\|Pain	February 2006	Phase 3
NCT02548195	Shanghai Zhongshan Hospital	Cholangiocarcinoma	July 2015	Phase 3
NCT00626158	University of California, San Francisco\|National Comprehensive Cancer Network	Pancreatic Cancer\|Biliary Cancer	February 2008	Phase 1
NCT05018182	West China Hospital	High-risk Locally Advanced Colorectal Cancer\|Neoadjuvant Chemotherapy\|FOLFOXIRI Regimen	August 2, 2021	Phase 2
NCT00658593	NCIC Clinical Trials Group\|Canadian Cancer Trials Group	Extrahepatic Bile Duct Cancer\|Gallbladder Cancer\|Liver Cancer	March 19, 2008	Phase 3
NCT02551237	UNICANCER	Rectal Carcinoma	January 7, 2016	Phase 3
NCT03169777	ImmunityBio, Inc.	Colorectal Cancer	August 2018	Phase 1\|Phase 2
NCT02280694	HaEmek Medical Center, Israel	Colorectal Cancer	January 2015	Phase 2
NCT04037241	Sorrento Therapeutics, Inc.	Malignant Tumor of Pancreas Metastatic to Liver	November 1, 2021	Phase 2\|Phase 3
NCT00415285	Georgia Center for Oncology Research & Education\|Sanofi	Breast Neoplasms	December 2006	Phase 2
NCT00717197	University of Florida	Malignant Glioma	July 2008	Phase 2
NCT01776307	Sumitomo Pharma Oncology, Inc.	Colorectal Cancer	March 2012	Phase 2
NCT00338039	M.D. Anderson Cancer Center\|Bristol-Myers Squibb	Pancreatic Cancer	September 2005	Phase 2
NCT03073785	Chi Lin, MD, PhD\|National Cancer Institute (NCI)\|University of Nebraska	Pancreatic Adenocarcinoma\|Recurrent Pancreatic Carcinoma\|Stage I Pancreatic Cancer AJCC v6 and v7\|Stage IA Pancreatic Cancer AJCC v6 and v7\|Stage IB Pancreatic Cancer AJCC v6 and v7\|Stage II Pancreatic Cancer AJCC v6 and v7\|Stage IIA Pancreatic Cancer AJCC v6 and v7\|Stage IIB Pancreatic Cancer AJCC v6 and v7\|Stage III Pancreatic Cancer AJCC v6 and v7\|Stage IV Pancreatic Cancer AJCC v6 and v7	September 16, 2016	Phase 2
NCT00021047	National Institutes of Health Clinical Center (CC)\|National Cancer Institute (NCI)	Esophageal Cancer\|Extrahepatic Bile Duct Cancer\|Gastric Cancer\|Head and Neck Cancer\|Liver Cancer\|Unspecified Adult Solid Tumor, Protocol Specific	July 2001	Phase 1\|Phase 2
NCT01182142	Kidney Cancer Research Bureau	Metastatic Renal Cell Carcinoma	September 2007	Phase 2
NCT01899118	Zhejiang Cancer Hospital	Locally Advanced Rectal Cancer	April 2013	Phase 2
NCT00076609	PhytoCeutica	Hepatocellular Carcinoma\|Liver Cancer	October 2003	Phase 1\|Phase 2
NCT01331928	Taipei Veterans General Hospital, Taiwan	Gastric Cancer	January 2011	Phase 2
NCT03114085	First Affiliated Hospital of Guangxi Medical University	Hepatocellular Carcinoma	May 20, 2017	Phase 2
NCT00008034	European Organisation for Research and Treatment of Cancer - EORTC	Breast Cancer	February 2000	Phase 1
NCT00081289	Radiation Therapy Oncology Group\|National Cancer Institute (NCI)	Colorectal Cancer	March 2004	Phase 2
NCT01808573	Puma Biotechnology, Inc.	HER2&addition; Metastatic Breast Cancer (MBC)	March 29, 2013	Phase 3
NCT01311050	King Faisal Specialist Hospital & Research Center	Metastatic Colorectal Cancer	January 2009
NCT04047862	BeiGene	Locally Advanced and Metastatic Solid Tumors	August 26, 2019	Phase 1
NCT02358356	Australasian Gastro-Intestinal Trials Group	Midgut Neuroendocrine Tumours\|Pancreatic Neuroendocrine Tumours	November 2015	Phase 2
NCT01273051	Radboud University Medical Center	Rectal Tumour	November 2010	Phase 2
NCT01963702	Fudan University	Gastric Cancer	August 2012	Phase 2
NCT04383275	Fudan University	Breast Cancer	May 15, 2020	Phase 2
NCT03473639	University of Virginia\|Syndax Pharmaceuticals	Metastatic Breast Cancer\|Breast Cancer	January 29, 2019	Phase 1
NCT04443348	Alice Ho\|Merck Sharp & Dohme LLC\|Breast Cancer Research Foundation\|Translational Breast Cancer Research Consortium\|Massachusetts General Hospital	Triple Negative Breast Cancer\|Hormone Receptor Positive (HR&addition;), HER2-negative Breast Cancer\|Biopsy-proven, Positive Lymph Node(s)	December 16, 2020	Phase 2
NCT02360501	Sun Yat-sen University	Nasopharyngeal Neoplasms	January 2008	Phase 2
NCT00829166	Hoffmann-La Roche	Breast Cancer	February 2009	Phase 3
NCT02678182	Royal Marsden NHS Foundation Trust\|MedImmune LLC\|Clovis Oncology, Inc.\|Eli Lilly and Company	Adenocarcinoma of the Oesophagus\|Adenocarcinoma of the Gastro-oesophageal Junction\|Adenocarcinoma of the Stomach	February 2015	Phase 2
NCT02931890	The Netherlands Cancer Institute	Gastric Cancer	December 21, 2017	Phase 2
NCT02287129	Technical University of Munich	Adenocarcinoma of the Esophagogastric Junction	November 2014	Phase 2
NCT04262635	Sun Yat-sen University	Colorectal Cancer	September 1, 2020	Phase 3
NCT00847119	Institut Català d´Oncologia\|Hoffmann-La Roche	Rectal Cancer	September 2007	Phase 2
NCT00113230	M.D. Anderson Cancer Center\|Genentech, Inc.	Rectal Cancer	February 2005	Phase 2
NCT00483834	University Health Network, Toronto\|Hoffmann-La Roche	Colorectal Cancer	December 2006	Phase 2
NCT01279681	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)\|Cancer and Leukemia Group B	Cognitive+Functional Effects\|Colorectal Cancer\|Neurotoxicity	January 2011	Phase 3
NCT00820222	Novartis Pharmaceuticals\|Novartis	Metastases, Brain	April 14, 2009	Phase 3
NCT00972881	University College, London	Rectal Cancer	April 2009	Phase 1\|Phase 2
NCT00101686	Pfizer	Colorectal Neoplasms	February 2003	Phase 3
NCT04664829	National Cancer Centre, Singapore\|National Medical Research Council (NMRC), Singapore	Metastatic Triple-Negative Breast Carcinoma	October 1, 2020	Phase 1
NCT00551213	Merck Sharp & Dohme LLC	Colorectal Cancer	November 21, 2007	Phase 2
NCT00003867	Montefiore Medical Center\|National Cancer Institute (NCI)	Cancer	March 1999	Phase 1
NCT01955629	Sanofi\|Regeneron Pharmaceuticals	Colorectal Cancer Metastatic	December 2013	Phase 1\|Phase 2
NCT00058318	Southwest Oncology Group\|National Cancer Institute (NCI)	Kidney Cancer	December 2004	Phase 2
NCT01298401	Radiation Therapy Oncology Group\|National Cancer Institute (NCI)\|NRG Oncology	Pancreatic Cancer	February 2012	Phase 1
NCT01193517	M.D. Anderson Cancer Center\|Celgene	Colorectal Cancer	August 2010	Phase 1\|Phase 2
NCT00121277	University Health Network, Toronto\|National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	September 2005	Phase 1
NCT00080301	R-Pharm	Breast Cancer\|Metastases	September 2003	Phase 3
NCT04406857	National Cancer Institute (NCI)	Locally Advanced Rectal Carcinoma\|Rectal Adenocarcinoma\|Stage II Rectal Cancer AJCC v8\|Stage III Rectal Cancer AJCC v8	October 7, 2020	Phase 1
NCT03887130	Pierre Fabre Medicament	Breast Cancer	March 2006	Phase 2
NCT03300544	National Cancer Institute (NCI)	Locally Advanced Rectal Adenocarcinoma\|Metastatic Rectal Adenocarcinoma\|Rectal Adenocarcinoma\|Stage III Rectal Cancer AJCC v7\|Stage IIIA Rectal Cancer AJCC v7\|Stage IIIB Rectal Cancer AJCC v7\|Stage IIIC Rectal Cancer AJCC v7\|Stage IV Rectal Cancer AJCC v7\|Stage IVA Rectal Cancer AJCC v7\|Stage IVB Rectal Cancer AJCC v7	September 20, 2017	Phase 1
NCT03577392	Sichuan Provincial People´s Hospital\|Jiangsu Simcere Pharmaceutical Co., Ltd.	Quality of Life	July 1, 2018	Phase 2\|Phase 3
NCT00040859	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Esophageal Cancer\|Gastric Cancer	September 2002	Phase 2
NCT00183898	University of Southern California\|Sanofi\|Roche Global Development\|Bristol-Myers Squibb	Gastric Cancer\|Esophageal Cancer	December 28, 2004	Phase 2
NCT01108107	Vejle Hospital\|Herlev Hospital	Colon Cancer	April 2010	Phase 2
NCT04411706	Xin-Hua Xu\|China Three Gorges University, Yichang, China	Hepatocellular Carcinoma	June 21, 2020	Phase 2
NCT00198237	Indiana University School of Medicine\|Aventis Pharmaceuticals\|Indiana University	Breast Cancer	March 2003	Phase 2
NCT02301143	Celgene	Pancreatic Neoplasms	April 21, 2015	Phase 2
NCT03561740	Sun Yat-sen University	Breast Cancer	July 25, 2018	Phase 3
NCT04248452	ECOG-ACRIN Cancer Research Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Clinical Stage IV Esophageal Adenocarcinoma AJCC v8\|Clinical Stage IV Gastric Cancer AJCC v8\|Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8\|Clinical Stage IVA Gastric Cancer AJCC v8\|Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8\|Clinical Stage IVB Gastric Cancer AJCC v8\|Metastatic Esophageal Adenocarcinoma\|Metastatic Gastric Adenocarcinoma\|Oligometastatic Esophageal Adenocarcinoma\|Oligometastatic Gastric Adenocarcinoma\|Pathologic Stage IV Esophageal Adenocarcinoma AJCC v8\|Pathologic Stage IV Gastric Cancer AJCC v8\|Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8\|Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8	February 6, 2020	Phase 3
NCT00462865	Brown University\|Women and Infants Hospital of Rhode Island\|Rhode Island Hospital\|The Miriam Hospital\|Memorial Hospital of Rhode Island\|University of New Mexico Cancer Center	Breast Cancer	November 2007	Phase 2
NCT00752063	The University of Hong Kong	Advanced Hepatocellular Carcinoma\|Metastatic Hepatocellular Carcinoma	September 2007	Phase 2
NCT00118300	Case Comprehensive Cancer Center\|National Cancer Institute (NCI)	Cervical Cancer\|Endometrial Cancer\|Ovarian Cancer\|Vaginal Cancer	April 2005	Phase 1
NCT00438100	Japan Breast Cancer Research Network	Breast Neoplasms	April 2008	Phase 2
NCT02362958	Sun Yat-sen University	HER2 Positive Breast Cancer	January 9, 2015	Phase 2
NCT03645876	Jiangsu HengRui Medicine Co., Ltd.	Metastatic Colorectal Cancer	November 8, 2018	Phase 2
NCT02526953	Blokhin´s Russian Cancer Research Center	Anus Neoplasms\|Carcinoma, Squamous Cell\|Anus Diseases\|Neoplasms\|Neoplasms, Squamous Cell\|Carcinoma	January 2016	Phase 3
NCT00868634	iOMEDICO AG\|Arbeitsgemeinschaft fur Internistische Onkologie\|Arbeitskreis Klinische Studien\|Roche Pharma AG	Metastatic Breast Cancer	February 2009	Phase 3
NCT04135781	Zhejiang Cancer Hospital\|CSPC Ouyi Pharmaceutical Co., Ltd.	Stomach Cancer	March 1, 2020	Phase 3
NCT04864067	Servicio de Salud Metropolitano Sur Oriente	Rectal Cancer	June 9, 2021	Phase 2
NCT03929666	Zymeworks Inc.	HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer	August 29, 2019	Phase 2
NCT05152147	Zymeworks Inc.\|BeiGene, Ltd.	Gastric Neoplasms\|Gastroesophageal Adenocarcinoma\|Esophageal Adenocarcinoma	December 2, 2021	Phase 3
NCT04608786	Lee´s Pharmaceutical Limited	Biliary Tract Cancer	February 1, 2021	Phase 1
NCT02694718	Hoffmann-La Roche\|Sanofi-Synthélabo (Schweiz) AG	Rectal Cancer	March 2005	Phase 2
NCT03015168	General Hospital of Ningxia Medical University	Rectal Cancer\|Prognosis	January 2012
NCT01450696	Hoffmann-La Roche	Gastric Cancer	December 2011	Phase 3
NCT00954876	Translational Genomics Research Institute\|Eli Lilly and Company	Metastatic Colorectal Cancer	August 2009	Phase 2
NCT04357587	Case Comprehensive Cancer Center	Rectal Neoplasms	August 6, 2020	Phase 1
NCT04696757	Kangbuk Samsung Hospital	Rectal Cancer\|Chemoradiotherapy\|Watch & Wait	February 1, 2018	Early Phase 1
NCT00225056	Oncology Specialties, Alabama	Metastatic Breast Cancer	October 2003	Phase 2
NCT00112918	Hoffmann-La Roche\|National Cancer Institute (NCI)	Colorectal Cancer	December 2004	Phase 3
NCT02954536	Memorial Sloan Kettering Cancer Center	Esophageal Cancer\|Gastric Cancer	November 3, 2016	Phase 2
NCT00514293	Raghu Nandan, M.D., Inc\|National Cancer Institute (NCI)	Lung Cancer	January 2007	Phase 2
NCT03213002	Northwell Health	Glioblastoma Multiforme (GBM)\|Glioblastoma\|Glioma of Brain\|Glioblastoma, Adult\|Brain Tumor\|Brain Tumor, Primary\|Brain Tumor Adult\|Cancer\|Brain Cancer	June 13, 2017	Phase 1\|Phase 2
NCT00532909	Branimir Sikic\|AstraZeneca\|Stanford University	Anal, Colon, and Rectal Cancers\|Colorectal Neoplasms\|Colon+Rectal Cancer	July 2006	Phase 1
NCT02981342	Eli Lilly and Company	Pancreatic Ductal Adenocarcinoma	January 12, 2017	Phase 2
NCT05108428	H. Lee Moffitt Cancer Center and Research Institute\|Viewray Inc.\|Natera, Inc.	Rectal Adenocarcinoma	October 23, 2021	Early Phase 1
NCT00755534	Hellenic Oncology Research Group\|University Hospital of Crete	Colorectal Cancer	November 2008	Phase 2
NCT05555888	Fudan University	Early Low Rectal Cancer	November 1, 2022	Phase 2
NCT00766155	European Organisation for Research and Treatment of Cancer - EORTC	Colorectal Cancer	August 2008	Phase 3
NCT04675983	Innovent Biologics (Suzhou) Co. Ltd.	Gastric Adenocarcinoma	March 10, 2021	Phase 3
NCT00661102	Hoffmann-La Roche	Breast Cancer	December 2008	Phase 3
NCT02873195	Academic and Community Cancer Research United\|National Cancer Institute (NCI)	Metastatic Colorectal Carcinoma\|Recurrent Colorectal Carcinoma\|Refractory Colorectal Carcinoma\|Stage IV Colorectal Cancer AJCC v7\|Stage IVA Colorectal Cancer AJCC v7\|Stage IVB Colorectal Cancer AJCC v7	July 7, 2017	Phase 2
NCT00083148	Roswell Park Cancer Institute	Breast Cancer	November 2002	Phase 1
NCT00216138	Hoosier Cancer Research Network\|Sanofi\|Hoffmann-La Roche\|Walther Cancer Institute	Head and Neck Cancer	March 2004	Phase 2
NCT03813784	Jiangsu HengRui Medicine Co., Ltd.	Gastric Cancer\|GastroEsophageal Cancer	March 7, 2019	Phase 3
NCT01095003	Pierre Fabre Medicament	Breast Cancer	May 2009	Phase 3
NCT01497392	Roswell Park Cancer Institute\|Novartis	Adenocarcinoma of the Pancreas\|Stage III Pancreatic Cancer\|Stage IV Pancreatic Cancer\|Unspecified Adult Solid Tumor, Protocol Specific	March 29, 2012	Phase 1
NCT00577057	Hospital Authority, Hong Kong\|Hong Kong Nasopharyngeal Cancer Study Group Limited	Nasopharyngeal Neoplasms	September 2006	Not Applicable
NCT03326674	Odonate Therapeutics, Inc.	Breast Cancer	December 21, 2017	Phase 3
NCT01333332	University of Virginia	Pancreatic Cancer	August 2010	Phase 2
NCT04258163	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University\|Sun Yat-sen University\|First People´s Hospital of Foshan	Metastatic Breast Cancer	January 1, 2019
NCT00614653	M.D. Anderson Cancer Center\|Genentech, Inc.	Pancreatic Cancer	January 2008	Phase 1
NCT00107276	Southwest Oncology Group\|National Cancer Institute (NCI)	Breast Cancer	August 2005	Phase 2
NCT01234337	Bayer\|Onyx Therapeutics, Inc.	Breast Cancer	February 21, 2011	Phase 3
NCT02746796	Ono Pharmaceutical Co. Ltd	Gastric Cancer	March 2016	Phase 2\|Phase 3
NCT00049244	R-Pharm\|National Cancer Institute (NCI)	Breast Cancer	September 2002	Phase 1
NCT02403544	Cancer Institute and Hospital, Chinese Academy of Medical Sciences\|Chia Tai Tianqing Pharmaceutical Group Co., Ltd.\|Sanofi	Carcinoma, Hepatocellular	September 2013	Phase 1
NCT03079427	Asan Medical Center\|Bundang CHA Hospital\|Seoul St. Mary´s Hospital\|Severance Hospital	Cholangiocarcinoma\|Biliary Tract Cancer\|Adjuvant Chemotherapy\|Capecitabine\|Gemcitabine\|Cisplatin	May 15, 2017	Phase 2
NCT00365417	NSABP Foundation Inc\|Genentech, Inc.\|Hoffmann-La Roche\|International Drug Development Institute	Breast Cancer	August 2006	Phase 2
NCT00506844	National Cancer Center, Korea	Rectal Neoplasms\|Neoadjuvant Treatment	May 2006	Phase 2
NCT02650752	Memorial Sloan Kettering Cancer Center\|Queens Cancer Center of Queens Hospital\|University of Michigan	Metastatic Breast Cancer\|Central Nervous System (CNS) Metastases	January 6, 2016	Phase 1
NCT02901301	Yonsei University	Gastric Cancer	February 6, 2017	Phase 1\|Phase 2
NCT00506168	National Cancer Center, Korea	Colorectal Neoplasms\|Secondary\|Drug Therapy, Combination	November 2001	Phase 2
NCT04859582	Merck Sharp & Dohme LLC	Stomach Neoplasms	November 8, 2018	Phase 3
NCT03011060	The First Hospital of Jilin University\|First Hospital of China Medical University\|The Second Affiliated Hospital of Harbin Medical University\|Qingdao University\|First Affiliated Hospital Xi´an Jiaotong University\|Baotou Cancer Hospital	Breast Neoplasm Female	December 2016	Phase 3
NCT01554969	Emory University\|Synta Pharmaceuticals Corp.	Rectal Cancer	May 2012	Phase 1
NCT05387603	Lund University Hospital	Neuroendocrine Tumors	June 2022	Phase 3
NCT01032057	Lisette Nixon\|Cardiff University	Pancreatic Cancer	July 2009	Phase 2
NCT00448552	University of Miami	Head and Neck Cancer	February 2004	Phase 2
NCT05368051	Beijing Friendship Hospital	Colorectal Neoplasms	October 1, 2021
NCT02213744	Merrimack Pharmaceuticals	Breast Cancer\|HER2 Positive Breast Cancer	July 2014	Phase 2\|Phase 3
NCT02028494	Latin American & Caribbean Society of Medical Oncology\|Breast Cancer Research Foundation	Breast Cancer	August 2013	Not Applicable
NCT01050322	Latin American Cooperative Oncology Group\|GlaxoSmithKline	BRMS1\|Performance Status Zero to Two for Beginning the Study\|Patient With a Maximum of One Chemotherapy\|Patient With Progression After Taxanes	November 2009	Phase 2
NCT03423849	Zhiyong Yu\|Shandong Cancer Hospital and Institute	Breast Cancer\|Chemotherapy Effect\|Disease-free Survival	February 8, 2018	Phase 2\|Phase 3
NCT02567331	Hoffmann-La Roche	Colorectal Cancer	October 2004	Phase 4
NCT03204734	Zhejiang Cancer Hospital	Breast Cancer	January 1, 2016	Phase 2
NCT02043821	Beijing Chao Yang Hospital	Metastatic Colorectal Cancer		Not Applicable
NCT03158610	Ruijin Hospital	Colorectal Cancer	January 29, 2018	Phase 2\|Phase 3
NCT04803539	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University\|Jiangsu HengRui Medicine Co., Ltd.	Breast Cancer	April 1, 2021	Phase 2\|Phase 3
NCT00081796	Sanofi	Breast Cancer\|Metastases	April 2004	Phase 3
NCT03396926	University of California, San Francisco\|Merck Sharp & Dohme LLC	Microsatellite Stable\|Mismatch Repair Protein Proficient\|Stage III Colorectal Cancer AJCC v7\|Stage IIIB Colorectal Cancer AJCC v7\|Stage IIIC Colorectal Cancer AJCC v7\|Stage IV Colorectal Cancer AJCC v7\|Stage IVA Colorectal Cancer AJCC v7\|Stage IVB Colorectal Cancer AJCC v7	April 18, 2018	Phase 2
NCT00087334	Roswell Park Cancer Institute	Colorectal Cancer	January 2004	Phase 1\|Phase 2
NCT04307147	Fudan University	Breast Cancer	July 3, 2018	Phase 3
NCT01310985	King Faisal Specialist Hospital & Research Center	Colon Rectal Cancer Duke Stage Stageval	March 2008
NCT03783442	BeiGene	Esophageal Squamous Cell Carcinoma (ESCC)	December 11, 2018	Phase 3
NCT00561522	Fudan University	Hepatocellular Carcinoma\|Neoplasm Metastasis	November 2007	Phase 2\|Phase 3
NCT02934529	Ludwig-Maximilians - University of Munich	Metastatic Colorectal Cancer	March 2015	Phase 3
NCT02178644	Yale University	Rectal Cancer	July 2014	Phase 1
NCT04274933	AbbVie	Breast Cancer\|Cancer	May 21, 2020	Phase 1
NCT05235542	Akeso	Advanced Malignant Tumors	July 12, 2022	Phase 1\|Phase 2
NCT04802980	Huabo Biopharm Co., Ltd.	Solid Tumor	April 28, 2020	Phase 1
NCT00630045	Peking University People´s Hospital\|Peking University\|Sanofi	Colorectal Cancer\|Resectable Liver Metastasis	January 2008	Phase 3
NCT00871273	Cambridge University Hospitals NHS Foundation Trust	Adenocarcinoma of the Stomach	November 2009	Phase 4
NCT00453323	National Cancer Center, Korea	Esophageal Cancer	June 2006	Phase 2
NCT00249977	University of New Mexico	Solid Tumors\|Cancer	April 2003	Phase 1
NCT02010567	UNC Lineberger Comprehensive Cancer Center\|Cerulean Pharma Inc.	Rectal Cancer	December 2013	Phase 1\|Phase 2
NCT05296005	Ohio State University Comprehensive Cancer Center	Clinical Stage I Gastric Cancer AJCC v8\|Clinical Stage II Gastric Cancer AJCC v8\|Clinical Stage IIA Gastric Cancer AJCC v8\|Clinical Stage IIB Gastric Cancer AJCC v8\|Clinical Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8\|Clinical Stage III Gastric Cancer AJCC v8\|Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8\|Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8\|Gastric Adenocarcinoma\|Pathologic Stage IB Gastric Cancer AJCC v8\|Pathologic Stage IC Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage II Gastric Cancer AJCC v8\|Pathologic Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage IIA Gastric Cancer AJCC v8\|Pathologic Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage IIB Gastric Cancer AJCC v8\|Pathologic Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage III Gastric Cancer AJCC v8\|Pathologic Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage IIIA Gastric Cancer AJCC v8\|Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage IIIB Gastric Cancer AJCC v8\|Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8\|Pathologic Stage IIIC Gastric Cancer AJCC v8\|Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8	May 31, 2022	Phase 1
NCT00114153	University of Virginia\|National Cancer Institute (NCI)	Head and Neck Cancer	June 2003	Phase 1
NCT04780347	Fudan University	Breast Cancer	December 15, 2020	Phase 2
NCT05089643	Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Metastatic Triple-Negative Breast Cancer	April 11, 2019	Phase 2
NCT00372944	AstraZeneca	Pancreatic Cancer	August 2006	Phase 2
NCT00130507	Spanish Breast Cancer Research Group\|Hoffmann-La Roche	Breast Cancer	November 4, 2005	Phase 2
NCT00194792	University of Washington\|National Cancer Institute (NCI)	Estrogen Receptor-positive Breast Cancer\|HER2-negative Breast Cancer\|Progesterone Receptor-positive Breast Cancer\|Stage I Breast Cancer\|Stage II Breast Cancer\|Stage IIIA Breast Cancer	August 2005	Phase 2
NCT00416494	Herbert Hurwitz, MD\|National Cancer Institute (NCI)\|Duke University	Colorectal Cancer	September 2003	Phase 2
NCT02414009	Fondazione IRCCS Istituto Nazionale dei Tumori, Milano	Metastatic Colorectal Cancer	September 2014	Phase 2
NCT05514275	Zhejiang Cancer Hospital	Nasopharyngeal Carcinoma	August 1, 2022	Phase 2
NCT00257348	University of California, Irvine\|Aventis Pharmaceuticals	Cervical Cancer	March 2004	Phase 2
NCT00996333	Columbia University\|Sanofi	Metastatic Pancreatic Cancer	June 2003	Phase 2
NCT05566743	Menoufia University	Cancer of Pancreas	September 11, 2022	Phase 2
NCT00297128	Austrian Breast & Colorectal Cancer Study Group\|Hoffmann-La Roche\|Merck Gesellschaft mbH, Austria	Rectal Cancer	October 2005	Phase 2
NCT05507112	Peking Union Medical College Hospital	Locally Advanced Rectal Cancer	September 20, 2022	Phase 2
NCT01494155	Massachusetts General Hospital	Pancreatic Cancer	December 2011	Phase 2
NCT03153280	Cancer Trials Ireland\|University College Cork	Colorectal Neoplasms\|Stomach Neoplasm\|Esophageal Neoplasms	January 13, 2022	Phase 1
NCT03050814	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Colorectal Tumors\|Colorectal Neoplasms\|Colorectal Carcinoma\|Colorectal Adenocarcinoma\|Colorectal Cancer	April 5, 2017	Phase 2
NCT03873532	Hutchison Medipharma Limited\|Hutchmed	Biliary Tract Cancer	July 10, 2018	Phase 2\|Phase 3
NCT02892123	Zymeworks Inc.	HER2-expressing Cancers	September 2016	Phase 1
NCT00684983	National Cancer Institute (NCI)\|Southwest Oncology Group	HER2 Positive Breast Carcinoma\|Recurrent Breast Carcinoma\|Stage IIIB Breast Cancer AJCC v7\|Stage IIIC Breast Cancer AJCC v7\|Stage IV Breast Cancer AJCC v6 and v7	July 30, 2008	Phase 2
NCT01783756	Jonsson Comprehensive Cancer Center	Central Nervous System Metastases\|HER2-positive Breast Cancer\|Male Breast Cancer\|Recurrent Breast Cancer\|Stage IV Breast Cancer	June 26, 2013	Phase 1\|Phase 2
NCT03349866	Hebei Medical University	Gastroesophageal Junction Adenocarcinoma	November 30, 2017	Phase 2
NCT05172518	Sun Yat-sen University\|Chengdu Biostar	Breast Neoplasms\|Locally Advanced or Metastatic Breast Cancer	March 1, 2022	Phase 3
NCT04539808	OHSU Knight Cancer Institute\|Oregon Health and Science University	Borderline Resectable Pancreatic Carcinoma\|Locally Advanced Unresectable Pancreatic Adenocarcinoma\|Resectable Pancreatic Ductal Adenocarcinoma\|Stage 0 Pancreatic Cancer AJCC v8\|Stage I Pancreatic Cancer AJCC v8\|Stage IA Pancreatic Cancer AJCC v8\|Stage IB Pancreatic Cancer AJCC v8\|Stage III Pancreatic Cancer AJCC v8\|Stage IV Pancreatic Cancer AJCC v8	May 27, 2021	Phase 2
NCT01434147	Austrian Breast & Colorectal Cancer Study Group\|Hoffmann-La Roche	Rectal Cancer	October 2011	Phase 2
NCT02137356	Sheba Medical Center\|Karyopharm Therapeutics Inc	Rectal Neoplasms	December 2014	Phase 1
NCT00006465	Case Comprehensive Cancer Center\|National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	December 2000	Phase 1
NCT00321100	Fox Chase Cancer Center	Colorectal Neoplasms	April 12, 2006	Phase 2
NCT03221426	Merck Sharp & Dohme LLC	Gastric Cancer\|Gastroesophageal Junction Cancer	October 9, 2017	Phase 3
NCT05062889	Gruppo Oncologico del Nord-Ovest\|Servier\|Foundation Medicine	Stage II Colon Cancer\|Stage III Colon Cancer	December 2022	Phase 2
NCT00338247	Novartis	Neoplasms, Breast	July 2006
NCT03564912	Zhejiang University	Colorectal Cancer	August 12, 2018	Phase 1\|Phase 2
NCT01783444	Novartis Pharmaceuticals\|Novartis	Breast Cancer	February 26, 2013	Phase 2
NCT00403429	National Cancer Institute, Naples	Ovarian Cancer	March 2006	Phase 2
NCT00436241	Hoffmann-La Roche	Gastric Cancer	March 2007	Phase 2
NCT00004183	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Malignant Mesothelioma	November 2000	Phase 2
NCT00514761	AstraZeneca	Metastatic Colorectal Cancer	September 2006	Phase 2
NCT00077077	Daiichi Sankyo, Inc.	Unspecified Adult Solid Tumor, Protocol Specific	February 2004	Phase 1
NCT01677884	Gustave Roussy, Cancer Campus, Grand Paris	Colorectal Neoplasms	November 2012	Phase 2
NCT00258232	Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Colorectal Cancer	January 2002	Phase 2
NCT01530503	IRCCS San Raffaele\|Regione Lombardia	Biliary Tract Cancer	November 2011	Phase 2
NCT02614794	Seagen Inc.	HER2 Positive Breast Cancer	January 28, 2016	Phase 2
NCT02017704	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|Nucletron	Rectal Cancer	June 12, 2014	Phase 2
NCT00207129	R-Pharm	Advanced Solid Tumors\|Neoplasms	October 2004	Phase 1
NCT01665274	Harbin Medical University	Gastric Cancer	September 2013	Phase 2
NCT00086931	Roswell Park Cancer Institute	Colorectal Cancer	September 2003	Phase 1\|Phase 2
NCT02393755	Roswell Park Cancer Institute\|National Cancer Institute (NCI)\|Boehringer Ingelheim\|National Comprehensive Cancer Network	Colon Adenocarcinoma\|Rectal Adenocarcinoma\|Recurrent Colon Carcinoma\|Recurrent Rectal Carcinoma\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer	May 8, 2015	Phase 1\|Phase 2
NCT00816634	Samsung Medical Center	First Line Chemotherapy\|Capecitabine Plus Cisplatin Versus Capecitabine Plus Paclitaxel\|Advanced or Recurrent Esophageal Squamous Cell Carcinoma	October 2008	Phase 2
NCT04681911	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Breast Cancer	September 9, 2020	Phase 2
NCT00938470	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Adenocarcinoma of the Gastroesophageal Junction\|Esophageal Cancer\|Gastric Cancer	January 2010	Phase 2
NCT00058474	NSABP Foundation Inc\|National Cancer Institute (NCI)\|Cancer and Leukemia Group B	Colorectal Cancer	July 2004	Phase 3
NCT02947061	Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Breast Cancer Recurrent	April 2015	Phase 2
NCT00824785	Royal Marsden NHS Foundation Trust	Oesophago-gastric Cancer	May 2008	Phase 3
NCT00070122	National Cancer Institute (NCI)	Adenocarcinoma of the Colon\|Adenocarcinoma of the Rectum\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage III Colon Cancer\|Stage III Rectal Cancer\|Stage IV Colon Cancer\|Stage IV Rectal Cancer	April 2004	Phase 3
NCT01050985	Georgetown University\|Wyeth is now a wholly owned subsidiary of Pfizer	Advanced Solid Tumors	July 2010	Phase 1
NCT00077363	National Cancer Institute (NCI)	Recurrent Breast Cancer\|Stage IV Breast Cancer	May 2004	Phase 2
NCT00797485	Southern Italy Cooperative Oncology Group\|National Cancer Institute (NCI)	Colorectal Cancer	July 2008	Phase 3
NCT01167049	Peking University Cancer Hospital & Institute\|Roche Pharma AG	Gastric Cancer	August 2009	Phase 2
NCT01887288	Western Regional Medical Center	Metastatic Breast Cancer	April 2013	Phase 2
NCT01069796	ARCAGY+ GINECO GROUP	Triple Negative Metastatic Breast Cancer	April 2010	Phase 2
NCT00812864	University Hospital, Limoges	Breast Cancer\|Colorectal Cancer	January 2009	Phase 4
NCT02736448	Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori	Gastro-entero-pancreatic Neuroendocrine Tumors	May 2016	Phase 2
NCT01439282	Eisai Inc.	Estrogen Receptor Positive Tumor\|Breast Cancer	August 2011	Phase 2
NCT03675737	Merck Sharp & Dohme LLC	Stomach Neoplasms	November 8, 2018	Phase 3
NCT01225523	Health Science Center of Xi´an Jiaotong University	Squamous Carcinoma of Esophagus\|Esophagus Disorders	January 1997	Phase 1
NCT04371224	Seoul National University Hospital	Pancreatic Cancer	June 23, 2020	Phase 2
NCT00177307	University of Pittsburgh\|Genentech, Inc.	Cancer	January 2005	Phase 2
NCT00583674	Amgen	Gastrointestinal Cancer	December 2007	Phase 2
NCT05040360	Southwest Oncology Group\|National Cancer Institute (NCI)	Metastatic Malignant Neoplasm in the Liver\|Pancreatic Neuroendocrine Tumor\|Stage I Pancreatic Neuroendocrine Tumor AJCC v8\|Stage II Pancreatic Neuroendocrine Tumor AJCC v8\|Stage III Pancreatic Neuroendocrine Tumor AJCC v8	October 14, 2021	Phase 2
NCT00265733	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Breast Cancer	February 2006	Phase 2
NCT05177133	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)\|Incyte Corporation	Gastric Adenocarcinoma\|Esophageal Adenocarcinoma	November 5, 2021	Phase 2
NCT01500993	Universitätsmedizin Mannheim	Rectal Cancer	March 2002	Phase 3
NCT01472770	Vejle Hospital	Metastatic Colorectal Cancer	October 2011	Phase 2
NCT00217711	Swiss Group for Clinical Cancer Research	Colorectal Cancer	May 2005	Phase 1\|Phase 2
NCT00889187	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital	Pancreatic Cancer	December 2009	Phase 1\|Phase 2
NCT04095299	Vejle Hospital	Cancer of Rectum	January 20, 2020	Phase 2
NCT00920868	Herbert Hurwitz, MD\|Bristol-Myers Squibb\|Duke University	Solid Tumor\|Metastatic Colorectal Cancer	May 2009	Phase 1
NCT01726452	Cancer Trials Ireland\|Southampton Clinical Trials Unit\|Region H Rigshospitalet\|Centre Hospitalier Régional, Universitaire de Lille	Adenocarcinoma of the Oesophagus\|Adenocarcinoma of the Oesophago-gastric Junction\|Oesophageal Tumours\|Junctional Tumours\|Oesophageal Cancer	January 24, 2013	Phase 3
NCT01730222	IRCCS San Raffaele	Pancreatic Cancer	November 2012	Phase 1\|Phase 2
NCT01471353	University of Florida\|Bayer	Colorectal Cancer Metastatic	November 2011	Phase 2
NCT01380808	Fudan University	Metastatic Breast Cancer	May 2011	Phase 2
NCT02715531	Hoffmann-La Roche	Solid Tumor	April 6, 2016	Phase 1
NCT00601627	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Pancreatic Cancer	June 2009	Phase 2
NCT00258284	Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Prostate Cancer	August 2003	Phase 2
NCT01589159	Tao OUYANG\|Peking University	Metastatic Breast Cancer	January 2013	Phase 2
NCT00088998	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Breast Cancer	December 2004	Phase 2
NCT00589901	Fudan University	Breast Cancer	August 2006	Phase 2
NCT00953537	Centre Antoine Lacassagne	Breast Cancer	January 2009	Not Applicable
NCT02243007	Massachusetts General Hospital	Resectable Pancreatic Cancer\|Pancreatic Ductal Carcinoma	September 2014	Phase 2
NCT03641547	University of Oxford\|Merck KGaA, Darmstadt, Germany	Oesophageal Adenocarcinoma\|Squamous Cell Carcinoma\|Solid Tumor	December 4, 2018	Phase 1
NCT03878524	OHSU Knight Cancer Institute\|Oregon Health and Science University	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Anatomic Stage IV Breast Cancer AJCC v8\|Anemia\|Ann Arbor Stage III Hodgkin Lymphoma\|Ann Arbor Stage III Non-Hodgkin Lymphoma\|Ann Arbor Stage IV Hodgkin Lymphoma\|Ann Arbor Stage IV Non-Hodgkin Lymphoma\|Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative\|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Castration-Resistant Prostate Carcinoma\|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Hematopoietic and Lymphoid System Neoplasm\|Locally Advanced Pancreatic Adenocarcinoma\|Metastatic Breast Carcinoma\|Metastatic Malignant Solid Neoplasm\|Metastatic Pancreatic Adenocarcinoma\|Myelodysplastic+Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Primary Myelofibrosis\|Recurrent Acute Lymphoblastic Leukemia\|Recurrent Acute Myeloid Leukemia\|Recurrent Chronic Lymphocytic Leukemia\|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Recurrent Hematologic Malignancy\|Recurrent Hodgkin Lymphoma\|Recurrent Myelodysplastic Syndrome\|Recurrent Myelodysplastic+Myeloproliferative Neoplasm\|Recurrent Myeloproliferative Neoplasm\|Recurrent Non-Hodgkin Lymphoma\|Recurrent Plasma Cell Myeloma\|Recurrent Small Lymphocytic Lymphoma\|Refractory Acute Lymphoblastic Leukemia\|Refractory Acute Myeloid Leukemia\|Refractory Chronic Lymphocytic Leukemia\|Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Refractory Chronic Myelomonocytic Leukemia\|Refractory Hematologic Malignancy\|Refractory Hodgkin Lymphoma\|Refractory Malignant Solid Neoplasm\|Refractory Myelodysplastic Syndrome\|Refractory Myelodysplastic+Myeloproliferative Neoplasm\|Refractory Non-Hodgkin Lymphoma\|Refractory Plasma Cell Myeloma\|Refractory Primary Myelofibrosis\|Refractory Small Lymphocytic Lymphoma\|Stage II Pancreatic Cancer AJCC v8\|Stage III Pancreatic Cancer AJCC v8\|Stage IV Pancreatic Cancer AJCC v8\|Stage IV Prostate Cancer AJCC v8\|Unresectable Pancreatic Adenocarcinoma	April 1, 2020	Phase 1
NCT01077427	Klinikum der Universitaet Muenchen, Grosshadern\|The European Society for Hyperthermic Oncology\|Ludwig-Maximilians - University of Munich	Resected Pancreatic Adenocarcinoma	March 2012	Phase 3
NCT00193102	SCRI Development Innovations, LLC\|Celgene Corporation	Breast Cancer	April 2001	Phase 2
NCT00450515	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Breast Cancer	March 2007	Phase 2
NCT00454649	Pfizer	Neoplasms	December 2005	Phase 1
NCT05374512	AstraZeneca\|Daiichi Sankyo, Inc.	Breast Cancer	May 16, 2022	Phase 3
NCT00743964	Samsung Medical Center	Advanced Gastric Cancer	April 2008	Phase 2
NCT00960284	IRCCS San Raffaele	Pancreatic Cancer	June 2003	Phase 2\|Phase 3
NCT00411229	Sanofi\|Hoffmann-La Roche	Stomach Neoplasms	June 2006	Phase 3
NCT00997685	Guangdong Provincial People´s Hospital	Potentially Resectable Liver Metastasis From CRC\|Colorectal Cancer	November 2009	Phase 2
NCT00077857	Hoffmann-La Roche	Breast Cancer	July 2003	Phase 2
NCT03930771	Weill Medical College of Cornell University	Recurrent Pituitary Adenomas	May 21, 2019	Phase 2
NCT00268463	NSABP Foundation Inc\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	January 2006	Phase 3
NCT03925233	Xijing Hospital	Breast Cancer Organoids	January 2, 2019
NCT00026234	National Cancer Institute (NCI)\|NSABP Foundation Inc	Adenocarcinoma of the Colon\|Adenocarcinoma of the Rectum\|Liver Metastases\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage IV Colon Cancer\|Stage IV Rectal Cancer	February 2002	Phase 2
NCT01326481	Tracon Pharmaceuticals Inc.\|Roswell Park Cancer Institute\|United States Department of Defense	Metastatic Breast Cancer	June 2011	Phase 1\|Phase 2
NCT00718913	Hellenic Oncology Research Group\|University Hospital of Crete	Gastric Cancer	April 2008	Phase 2
NCT02973737	Jiangsu HengRui Medicine Co., Ltd.	HER2 Positive Metastatic Breast Cancer	July 20, 2016	Phase 3
NCT05336721	Chipscreen Biosciences, Ltd.	Triple-negative Breast Cancer	November 5, 2021	Phase 2
NCT00032175	Cancer Research UK\|National Cancer Institute (NCI)	Pancreatic Cancer	April 2002	Phase 3
NCT00562718	University of Texas Southwestern Medical Center	Breast Cancer	September 2004	Phase 2
NCT00496366	Rutgers, The State University of New Jersey\|National Cancer Institute (NCI)\|Rutgers Cancer Institute of New Jersey	Breast Cancer\|Metastatic Breast Cancer\|Advanced Breast Cancer\|HER2+Neu-positive Breast Cancer	July 23, 2007	Phase 2
NCT01716949	University of Erlangen-Nürnberg Medical School	Rectal Cancer	September 2012	Phase 1\|Phase 2
NCT00966706	IRCCS San Raffaele	Pancreatic Cancer	June 2005	Phase 2
NCT04663763	Zhejiang Cancer Hospital	Locally Advanced Rectal Cancer	December 1, 2020	Phase 2
NCT00780494	Pamela L. Kunz\|Genentech, Inc.\|Stanford University	Stomach Cancer\|Gastric (Stomach) Cancer\|Neoplasm of Cardioesophageal Junction\|Gastrointestinal Stromal Tumor (GIST)	February 2009	Phase 2
NCT04262687	Federation Francophone de Cancerologie Digestive	Colorectal Cancer Metastatic\|High Immune Infiltrate\|Microsatellite Stable	April 6, 2021	Phase 2
NCT00534417	Accelerated Community Oncology Research Network\|Hoffmann-La Roche\|AstraZeneca	Metastatic Breast Cancer	October 2007	Phase 2
NCT02229149	US Oncology Research\|Genentech, Inc.	Breast Neoplasms\|Malignant Tumor of the Breast	December 2014	Phase 2
NCT00276744	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|National Cancer Institute (NCI)	Pancreatic Cancer	October 2005	Phase 2
NCT04259944	IFOM, The FIRC Institute of Molecular Oncology\|Guardant Health, Inc.	Colon Cancer	June 16, 2020	Phase 2
NCT02028507	Spanish Breast Cancer Research Group\|Pfizer\|AstraZeneca	Metastatic Breast Cancer	March 13, 2014	Phase 3
NCT01206049	Vejle Hospital	Cholangiocarcinoma	September 2010	Phase 2
NCT02423954	Western Regional Medical Center	Advanced Cancer\|Pancreatic Cancer\|Renal Cell Cancer\|Non Small Cell Lung Cancer\|Colorectal Carcinoma\|Endometrial\|Uterine	April 2015	Phase 1\|Phase 2
NCT03044730	Northwestern University\|Merck Sharp & Dohme LLC\|National Cancer Institute (NCI)	Estrogen Receptor Negative\|HER2+Neu Negative\|Progesterone Receptor Negative\|Recurrent Breast Carcinoma\|Stage III Breast Cancer\|Stage IIIA Breast Cancer\|Stage IIIB Breast Cancer\|Stage IIIC Breast Cancer\|Stage IV Breast Cancer\|Triple-Negative Breast Carcinoma	May 25, 2017	Phase 2
NCT01711242	xie congying\|Wenzhou Medical University	Gastric Cancer	January 2012	Phase 2
NCT00351195	Rigshospitalet, Denmark\|Morten Ladekarl, MD, DMSc., Dept. of Oncology, �rhus Sygehus, �rhus	Hepatocellular Carcinoma	February 2006	Phase 2
NCT04523818	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Clinical Stage I Gastric Cancer AJCC v8\|Clinical Stage IIA Gastric Cancer AJCC v8\|Clinical Stage III Gastric Cancer AJCC v8\|Clinical Stage IVA Gastric Cancer AJCC v8\|Gastric Adenocarcinoma\|Pathologic Stage IB Gastric Cancer AJCC v8\|Pathologic Stage II Gastric Cancer AJCC v8\|Pathologic Stage IIA Gastric Cancer AJCC v8\|Pathologic Stage IIB Gastric Cancer AJCC v8\|Pathologic Stage III Gastric Cancer AJCC v8\|Pathologic Stage IIIA Gastric Cancer AJCC v8\|Pathologic Stage IIIB Gastric Cancer AJCC v8\|Pathologic Stage IIIC Gastric Cancer AJCC v8\|Postneoadjuvant Therapy Stage I Gastric Cancer AJCC v8\|Postneoadjuvant Therapy Stage II Gastric Cancer AJCC v8\|Postneoadjuvant Therapy Stage III Gastric Cancer AJCC v8	August 11, 2020	Phase 1
NCT00960544	M.D. Anderson Cancer Center\|Myriad Genetic Laboratories, Inc.	Breast Cancer	January 2019	Phase 2
NCT04908813	Shanghai Henlius Biotech	Gastric Cancer	September 29, 2021	Phase 2
NCT02297230	NYU Langone Health	Breast Cancer	June 2002	Phase 1\|Phase 2
NCT00009737	Hoffmann-La Roche	Colorectal Cancer	November 1998	Phase 3
NCT00329329	Agennix	Malignancies	May 2006	Phase 1
NCT03872388	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Anatomic Stage IIB Breast Cancer AJCC v8\|Anatomic Stage III Breast Cancer AJCC v8\|Anatomic Stage IIIA Breast Cancer AJCC v8\|Anatomic Stage IIIB Breast Cancer AJCC v8\|Anatomic Stage IIIC Breast Cancer AJCC v8\|Estrogen Receptor Negative\|HER2+Neu Negative\|Inflammatory Breast Carcinoma\|Progesterone Receptor Negative\|Prognostic Stage IIB Breast Cancer AJCC v8\|Prognostic Stage III Breast Cancer AJCC v8\|Prognostic Stage IIIA Breast Cancer AJCC v8\|Prognostic Stage IIIB Breast Cancer AJCC v8\|Prognostic Stage IIIC Breast Cancer AJCC v8\|Stage IIB Breast Cancer AJCC v6 and v7\|Stage III Breast Cancer AJCC v7\|Stage IIIA Breast Cancer AJCC v7\|Stage IIIB Breast Cancer AJCC v7\|Stage IIIC Breast Cancer AJCC v7\|Triple-Negative Breast Carcinoma	January 14, 2019	Phase 2
NCT01697072	Amgen	Gastric Cancer	October 2012	Phase 3
NCT00290693	University of Miami	Pancreatic Cancer	July 2004	Phase 2
NCT03708536	Fujian Cancer Hospital	Colorectal Adenocarcinoma	November 2018	Phase 3
NCT00431106	Hellenic Oncology Research Group\|University Hospital of Crete	Breast Cancer	April 2002	Phase 3
NCT00177255	University of Pittsburgh\|Aventis Pharmaceuticals\|Roche Pharma AG	Cancer	April 2005	Phase 2
NCT02294786	Novartis Pharmaceuticals\|Novartis	Cancer	December 17, 2014	Phase 2
NCT00511446	Martin-Luther-Universität Halle-Wittenberg	Stomach Neoplasms	August 2007	Phase 2
NCT00070265	National Cancer Institute (NCI)	Liver Metastases\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage IV Colon Cancer\|Stage IV Rectal Cancer	August 2003	Phase 2
NCT01015339	Peking University\|Roche Pharma AG	Advanced Gastric Cancer	November 2009	Phase 3
NCT03535727	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Adenocarcinoma\|Pancreatic Neoplasms\|Neoplasm, Glandular\|Neoplasms\|Neoplasms Pancreatic\|Digestive System Neoplasm\|Endocrine Gland Neoplasms\|Digestive System Disease\|Pancreatic Diseases\|Endocrine System Diseases	June 21, 2018	Phase 1\|Phase 2
NCT03117855	City of Hope Medical Center\|National Cancer Institute (NCI)	Bile Duct Adenocarcinoma\|Stage III Intrahepatic Cholangiocarcinoma\|Stage IVA Intrahepatic Cholangiocarcinoma\|Stage IVB Intrahepatic Cholangiocarcinoma	December 2016	Phase 1
NCT03777657	BeiGene	Gastric, or Gastroesophageal Junction Adenocarcinoma	December 13, 2018	Phase 3
NCT03295084	Dorte Nielsen\|Herlev Hospital	Metastatic Colorectal Cancer	July 15, 2015	Phase 1
NCT00119171	GlaxoSmithKline	Solid Tumor Cancer	November 2004	Phase 1
NCT02038621	The Second People´s Hospital of Sichuan	Advanced Gastric Cancer	January 2014	Phase 2
NCT00074321	National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	November 2003	Phase 1
NCT00873353	Grupo Gallego de Investigaciones Oncologicas	Metastatic Adenocarcinoma of the Pancreas	March 2008	Phase 2
NCT02633176	Sun Yat-sen University\|Chinese Southwest Oncology Group	Nasopharyngeal Carcinoma	January 2015	Phase 3
NCT05610163	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Locally Advanced Rectal Carcinoma\|Stage II Rectal Cancer AJCC v8\|Stage III Rectal Cancer AJCC v8	November 9, 2022	Phase 2
NCT00070252	National Cancer Institute (NCI)	Adult Solid Neoplasm\|Inflammatory Breast Carcinoma\|Male Breast Carcinoma\|Stage IIIA Breast Cancer\|Stage IIIB Breast Cancer	September 2003	Phase 1\|Phase 2
NCT01611506	Dr Anna Dorothea Wagner\|Centre Hospitalier Universitaire Vaudois	Gastric Cancer	February 2012	Phase 1\|Phase 2
NCT02013830	Hoffmann-La Roche	Liver Cancer	May 2005	Phase 2
NCT03042000	Peking Union Medical College Hospital\|Beijing Hospital\|Beijing Chao Yang Hospital\|Cancer Institute and Hospital, Chinese Academy of Medical Sciences\|Peking University People´s Hospital\|Peking University Cancer Hospital & Institute\|Beijing Friendship Hospital\|Geneplus-Beijing Co. Ltd.	Rectal Cancer, Adenocarcinoma\|Neoadjuvant Chemoradiation	February 2017	Not Applicable
NCT02734290	Providence Health & Services\|Merck Sharp & Dohme LLC	Triple Negative Breast Cancer	February 23, 2016	Phase 1\|Phase 2
NCT02137343	Amgen	Gastric Cancer	July 2014	Phase 3
NCT00043121	National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	June 2002	Phase 1
NCT00345696	Unidad Integral de Investigación en Oncología S.L.\|Hoffmann-La Roche	Metastatic Colorectal Cancer	June 2006	Phase 2
NCT03818685	Centre Leon Berard	Breast Cancer\|Triple Negative Breast Neoplasms	July 2, 2019	Phase 2
NCT03563170	ImmunityBio, Inc.	Hepatocellular Carcinoma Non-resectable\|Hepatocellular Carcinoma Recurrent	May 25, 2018	Phase 1\|Phase 2
NCT01798251	Harbin Medical University	Gastric Cancer	December 2012	Phase 2
NCT02854072	Samsung Pharmaceutical Co., Ltd.	Pancreatic Cancer	November 2015	Phase 3
NCT01081262	National Cancer Institute (NCI)\|NRG Oncology	Borderline Ovarian Mucinous Tumor\|Ovarian Mucinous Cystadenocarcinoma\|Recurrent Fallopian Tube Carcinoma\|Recurrent Ovarian Carcinoma\|Stage IA Fallopian Tube Cancer AJCC v6 and v7\|Stage IA Ovarian Cancer AJCC v6 and v7\|Stage IB Fallopian Tube Cancer AJCC v6 and v7\|Stage IB Ovarian Cancer AJCC v6 and v7\|Stage IC Fallopian Tube Cancer AJCC v6 and v7\|Stage IC Ovarian Cancer AJCC v6 and v7\|Stage IIA Fallopian Tube Cancer AJCC v6 and v7\|Stage IIA Ovarian Cancer AJCC V6 and v7\|Stage IIB Fallopian Tube Cancer AJCC v6 and v7\|Stage IIB Ovarian Cancer AJCC v6 and v7\|Stage IIC Fallopian Tube Cancer AJCC v6 and v7\|Stage IIC Ovarian Cancer AJCC v6 and v7\|Stage IIIA Fallopian Tube Cancer AJCC v7\|Stage IIIA Ovarian Cancer AJCC v6 and v7\|Stage IIIB Fallopian Tube Cancer AJCC v7\|Stage IIIB Ovarian Cancer AJCC v6 and v7\|Stage IIIC Fallopian Tube Cancer AJCC v7\|Stage IIIC Ovarian Cancer AJCC v6 and v7\|Stage IV Fallopian Tube Cancer AJCC v6 and v7\|Stage IV Ovarian Cancer AJCC v6 and v7	October 12, 2010	Phase 3
NCT00084643	National Cancer Institute (NCI)	Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage IIIC Colon Cancer\|Stage IIIC Rectal Cancer\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer\|Unspecified Adult Solid Tumor, Protocol Specific	May 2004	Phase 1
NCT04517214	Fudan University\|Fudan University Eye and ENT Hospital\|Anhui Provincial Hospital\|Sir Run Run Shaw Hospital\|Hangzhou Cancer Hospital\|Ningbo Medical Center Lihuili Hospital\|The First People´s Hospital of Changzhou\|Cancer Hospital of Chinese Academy of Medical Science, Shenzhen Center\|Affiliated Cancer Hospital & Institute of Guangzhou Medical University\|Nanfang Hospital of Southern Medical University\|Shenzhen People´s Hospital\|First Affiliated Hospital of Xi´anJiaotong Univerisity\|Guangzhou Panyu Central Hospital	Nasopharyngeal Carcinoma	November 1, 2020	Phase 2
NCT01847599	Centre Jean Perrin	Metastatic Breast Cancer\|Colorectal Cancer	September 6, 2011	Not Applicable
NCT00357253	Pediatric Brain Tumor Consortium\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors	January 2006	Phase 1
NCT02586610	Osama Rahma, MD\|Hoosier Cancer Research Network\|Merck Sharp & Dohme LLC	Rectal Cancer\|Rectal Neoplasm	October 2016	Phase 2
NCT00266279	University of Louisville\|James Graham Brown Cancer Center	Head or Neck Cancer	April 2005	Phase 2
NCT00142038	Charite University, Berlin, Germany	Stomach Neoplasm\|Neoplasm Metastasis	March 2004	Phase 2
NCT05429684	First Affiliated Hospital Xi´an Jiaotong University	HER2&addition; Breast Cancer	January 1, 2021	Phase 3
NCT00434941	Spanish Breast Cancer Research Group\|Hoffmann-La Roche	Breast Cancer	September 2007	Phase 2
NCT01167725	Walter Reed Army Medical Center\|National Cancer Institute (NCI)	Colorectal Cancer	August 2010	Phase 3
NCT01131195	Swiss Group for Clinical Cancer Research	Breast Cancer	July 19, 2010	Phase 3
NCT00418028	Hospital San Carlos, Madrid\|Complexo Hospitalario Universitario de A Coruña	Metastatic Breast Cancer	September 2005	Phase 2\|Phase 3
NCT03038217	Peking Union Medical College Hospital\|Geneplus-Beijing Co. Ltd.	Rectal Cancer, Adenocarcinoma\|Neoadjuvant Chemoradiation	February 2017	Phase 3
NCT00408564	Medical University of South Carolina	Pancreatic Cancer	January 2006	Phase 2
NCT00674167	National University Hospital, Singapore	Gastric Cancer	May 2007	Phase 2
NCT00869050	Columbia University	Neuroendocrine Tumors	August 2005	Phase 2
NCT03427359	The University of Hong Kong-Shenzhen Hospital	Nasopharyngeal Carcinoma	January 22, 2015	Phase 2
NCT05136326	Fondazione IRCCS Istituto Nazionale dei Tumori, Milano	Rectal Cancer	December 1, 2021	Phase 2
NCT00048139	Hoffmann-La Roche	Colorectal Cancer	October 2001	Phase 2
NCT02604615	The First Affiliated Hospital of Henan University of Science and Technology\|The First Affiliated Hospital of Zhengzhou University\|Xinyang Central Hospital\|Anyang Tumor Hospital\|No. 150 Central Hospital of the Chinese People Liberation Army	Stage III Esophageal Squamous Cell Carcinoma\|Esophageal Neoplasms	October 2014	Phase 3
NCT01634685	University of Texas Southwestern Medical Center	Rectal Adenocarcinoma	August 8, 2012	Phase 1
NCT00084617	National Cancer Institute (NCI)	Adenocarcinoma of the Gastroesophageal Junction\|Diffuse Adenocarcinoma of the Stomach\|Intestinal Adenocarcinoma of the Stomach\|Mixed Adenocarcinoma of the Stomach\|Recurrent Gastric Cancer\|Stage IIIA Gastric Cancer\|Stage IIIB Gastric Cancer\|Stage IIIC Gastric Cancer\|Stage IV Gastric Cancer	March 2004	Phase 2
NCT00438256	Massachusetts General Hospital\|Dana-Farber Cancer Institute\|National Cancer Institute (NCI)	Pancreatic Cancer	December 2007	Phase 1\|Phase 2
NCT00480584	H. Lee Moffitt Cancer Center and Research Institute\|Genentech, Inc.	Metastatic Pancreatic Carcinoma	April 2007	Phase 1
NCT00220051	Royal Marsden NHS Foundation Trust	Rectal Cancer	November 2001	Phase 2
NCT00125021	Dana-Farber Cancer Institute\|Genentech, Inc.\|Roche Global Development\|Brigham and Women´s Hospital\|Massachusetts General Hospital\|Beth Israel Deaconess Medical Center	Pancreatic Cancer\|Neoplasm Metastasis	October 2003	Phase 2
NCT01128842	Puma Biotechnology, Inc.	Advanced Malignant Solid Tumors	April 2010	Phase 1
NCT05390476	wang shusen\|Sun Yat-sen University	Triple Negative Breast Cancer	August 1, 2022	Phase 2
NCT01640665	Yale University\|Bayer	Metastatic Breast Cancer\|Gastrointestinal Tumors	July 2012	Phase 1
NCT00176735	University of Michigan Rogel Cancer Center	Pancreatic Cancer	December 2001	Not Applicable
NCT01844076	Fox Chase Cancer Center	Colorectal Adenocarcinoma	January 14, 2016	Phase 1\|Phase 2
NCT00084591	Fox Chase Cancer Center\|National Cancer Institute (NCI)	Colorectal Cancer	December 2003	Phase 1
NCT00107315	Roswell Park Cancer Institute	Colorectal Cancer	July 2004	Phase 2
NCT03839823	Novartis Pharmaceuticals\|Novartis	Breast Cancer	February 25, 2019	Phase 2
NCT02177552	Rigshospitalet, Denmark	Esophageal Neoplasms\|Stomach Neoplasms	June 2014	Phase 2
NCT00201435	Norwegian Breast Cancer Group	Breast Neoplasm	March 2005	Phase 2\|Phase 3
NCT00845910	Hoffmann-La Roche	Breast Cancer	May 2009	Phase 2
NCT00220129	Royal Marsden NHS Foundation Trust	Oesophageal Carcinoma	November 2002	Phase 2
NCT00345761	Chugai Pharmaceutical\|Yakult Honsha Co., LTD	Colorectal Cancer	February 2006	Phase 1\|Phase 2
NCT04808323	Medical College of Wisconsin	Rectal Adenocarcinoma	June 17, 2021	Phase 1
NCT01079702	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	Advanced Malignancies	April 2008	Phase 1\|Phase 2
NCT03080805	Jiangsu HengRui Medicine Co., Ltd.	HER2 Positive Metastatic Breast Cancer	May 3, 2017	Phase 3
NCT03609489	First Affiliated Hospital of Guangxi Medical University	Biliary Carcinoma	September 10, 2018	Phase 2
NCT02022852	Harbin Medical University	Rectal Cancer	July 2013	Phase 2
NCT04164199	BeiGene	Advanced Malignancies	December 19, 2019	Phase 3
NCT00909987	Grupo Espanol Multidisciplinario del Cancer Digestivo\|Royal Marsden NHS Foundation Trust	Rectum Cancer	March 2009	Phase 2
NCT01997333	Celldex Therapeutics	Metastatic gpNMB Over-expressing Triple Negative Breast Cancer	November 2013	Phase 2
NCT01213238	M.D. Anderson Cancer Center	Advanced Cancers	September 30, 2010	Phase 1
NCT03775928	Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Triple-negative Breast Cancer	December 18, 2018	Phase 2
NCT04065282	First Affiliated Hospital of Zhejiang University	Gastric Cancer	August 6, 2019	Phase 2
NCT00440622	Hellenic Oncology Research Group\|University Hospital of Crete	Breast Cancer	April 2003	Phase 3
NCT03146377	The University of Hong Kong	Colorectal Cancer	April 2014	Phase 2
NCT00305877	National Cancer Institute (NCI)	Stage IA Pancreatic Cancer\|Stage IB Pancreatic Cancer\|Stage IIA Pancreatic Cancer\|Stage IIB Pancreatic Cancer	February 2006	Phase 2
NCT03322215	Theodoros Foukakis\|Karolinska University Hospital	Breast Cancer Metastatic	October 24, 2017	Phase 2
NCT00470184	Roswell Park Cancer Institute\|National Comprehensive Cancer Network	Esophageal Cancer	November 2006	Phase 2
NCT03921684	Baruch Brenner\|Bristol-Myers Squibb\|Rabin Medical Center	Rectal Cancer	April 2019	Phase 2
NCT03607656	Shanghai University of Traditional Chinese Medicine\|RenJi Hospital\|Jiangsu Province Hospital of Traditional Chinese Medicine	Gastric Cancer Stage IIIB\|Gastric Cancer Stage IIIC	June 8, 2018	Phase 2\|Phase 3
NCT00354887	M.D. Anderson Cancer Center\|Sanofi-Synthelabo	Gastrointestinal Cancer	November 2004	Phase 2
NCT02248571	iOMEDICO AG\|Arbeitsgemeinschaft fur Internistische Onkologie\|Novartis Pharmaceuticals	Breast Cancer Recurrent\|HER2+Neu-negative Carcinoma of Breast\|Hormone Receptor Positive Malignant Neoplasm of Breast	August 2014	Phase 4
NCT04997837	Fudan University	Gastric Cancer	July 21, 2021	Phase 3
NCT04310176	National Cancer Institute, Naples	Ras-mutated Metastatic Colorectal Cancer	May 24, 2019	Phase 2
NCT01641458	Cantonal Hospital of St. Gallen\|University of Bern	Colorectal Cancer	October 2012	Phase 4
NCT02597868	Zhejiang Cancer Hospital\|307 Hospital of PLA\|Fudan University\|The Tumor Hospital of Jiangsu Province\|Fujian Province Tumor Hospital\|Zhejiang University\|Sir Run Run Shaw Hospital\|Zhejiang Chinese Medical University\|Hangzhou Cancer Hospital\|Jiangsu Provincial People´s Hospital	Breast Cancer	January 2013	Not Applicable
NCT02915172	M.D. Anderson Cancer Center\|Eisai Inc.	Advanced Cancer\|Malignant Neoplasm of Breast\|Malignant Neoplasms of Bone and Articular Cartilage\|Malignant Neoplasms of Digestive Organs\|Malignant Neoplasms of Eye Brain and Other Parts of Central Nervous System\|Malignant Neoplasms of Female Genital Organs\|Malignant Neoplasms of Ill-defined Secondary and Unspecified Sites\|Malignant Neoplasms of Independent (Primary) Multiple Sites\|Malignant Neoplasms of Lip Oral Cavity and Pharynx\|Malignant Neoplasms of Male Genital Organs\|Malignant Neoplasms of Mesothelial and Soft Tissue\|Malignant Neoplasms of Respiratory and Intrathoracic Organs\|Malignant Neoplasms of Thyroid and Other Endocrine Glands\|Malignant Neoplasms of Urinary Tract	December 2016	Phase 1
NCT02218164	H. Lee Moffitt Cancer Center and Research Institute	Squamous Cell Carcinoma of Skin\|Carcinoma, Squamous Cell	August 12, 2014	Phase 2
NCT00814619	Swiss Group for Clinical Cancer Research	Colorectal Cancer	November 2008	Phase 2
NCT04097444	Chugai Pharmaceutical	Metastatic Colorectal Cancer	October 11, 2019	Phase 2
NCT00547547	City of Hope Medical Center\|National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	April 2006	Phase 1
NCT00379262	Hong Kong Nasopharyngeal Cancer Study Group Limited\|The Hong Kong Anti-Cancer Society\|hong Kong Cancer Fund	Nasopharyngeal Carcinoma	September 2006	Phase 3
NCT00258310	Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Head and Neck Cancer	December 2003	Phase 2
NCT01918644	University of Wisconsin, Madison	Stage IA Pancreatic Cancer\|Stage IB Pancreatic Cancer\|Stage IIA Pancreatic Cancer\|Stage IIB Pancreatic Cancer	April 8, 2014	Phase 1
NCT03653507	Astellas Pharma Global Development, Inc.\|Astellas Pharma Inc	Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer\|Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer\|Metastatic Gastric Adenocarcinoma or Cancer\|Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma	November 28, 2018	Phase 3
NCT04894643	EBG MedAustron GmbH\|Landesklinkum Wiener Neustadt	Pancreatic Cancer\|Proton Therapy	September 14, 2020	Not Applicable
NCT00496301	Spanish Oncology Genito-Urinary Group	Carcinoma, Renal Cell	November 2006	Phase 2
NCT01268943	Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Rectal Neoplasms	November 2010	Phase 1
NCT05063786	Spanish Breast Cancer Research Group\|ETOP IBCSG Partners Foundation\|Breast International Group\|Novartis Pharmaceuticals	Advanced Breast Cancer	September 14, 2021	Phase 3
NCT04404491	The First Affiliated Hospital of Henan University of Science and Technology	Esophageal Malignant Neoplasm, Local Recurrence	June 1, 2020	Phase 3
NCT01516944	Hebei Medical University	Gastric Cancer	February 2012	Phase 2\|Phase 3
NCT00977379	Hoffmann-La Roche	Breast Cancer	August 2009	Phase 2
NCT00502671	Hoffmann-La Roche	Colorectal Cancer	July 2007	Phase 4
NCT00324610	Association Pour La Recherche des Thérapeutiques Innovantes en Cancérologie	Breast Neoplasms\|Chemotherapy	March 2006	Phase 1\|Phase 2
NCT02767661	Sun Yat-sen University	Breast Cancer	July 19, 2017	Phase 3
NCT04072107	Sun Yat-sen University\|National Cancer Centre, Singapore\|Wuzhou Red Cross Hospital\|First People´s Hospital of Foshan	Nasopharyngeal Carcinoma	June 1, 2020	Phase 2
NCT04501523	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Triple-negative Breast Cancer	August 3, 2020	Phase 2
NCT03770689	EMD Serono Research & Development Institute, Inc.\|Merck KGaA, Darmstadt, Germany\|EMD Serono	Locally Advanced Rectal Cancer	March 20, 2019	Phase 1\|Phase 2
NCT01354522	Peking Union Medical College Hospital	Breast Cancer	May 2011	Phase 3
NCT00848783	NYU Langone Health	Gastric Cancer\|Gastric Adenocarcinoma\|Esophageal Cancer	May 2008	Phase 2
NCT01461057	Hoffmann-La Roche	Gastric Cancer	December 6, 2011	Phase 2
NCT02514278	University Hospital, Bordeaux	Rectal Cancer	January 28, 2016	Phase 3
NCT00216424	James A. Haley Veterans Administration Hospital\|Hoffmann-La Roche	Colorectal Cancer	February 2005	Phase 4
NCT00078572	GlaxoSmithKline	Breast Cancer	March 2004	Phase 3
NCT01123473	European Organisation for Research and Treatment of Cancer - EORTC	Adenocarcinoma of the Gastroesophageal Junction\|Gastric Cancer	December 2010	Phase 2
NCT01195298	South Eastern European Research Oncology Group\|Roche Pharma AG	Breast Cancer\|Metastasis	May 2010	Phase 2
NCT02076594	Gruppo Italiano per lo studio dei Carcinomi dell´Apparato Digerente\|Regione Lombardia	Locally Advanced Unresectable Gastric Cancer\|Metastatic Gastric Cancer	January 2013	Phase 3
NCT05044117	Sun Yat-sen University\|Fujian Medical University Union Hospital\|Guangzhou Panyu Central Hospital\|The Central Hospital of Yongzhou\|The First People´s Hospital of Huaihua\|Hanzhong Central Hospital\|Yichang Central People´s Hospital\|The Affiliated Hospital of Guangdong Medical College\|Jiangmen Central Hospital\|Xiang Yang No.1 Peoples Hospital	Head and Neck Squamous Cell Carcinoma	October 18, 2021	Phase 3
NCT00345059	National Cancer Institute, Naples	Advanced Non-Small Cell Lung Cancer	May 2005	Phase 3
NCT00881621	Georgetown University\|GlaxoSmithKline	Pancreas Cancer	August 2009	Phase 2
NCT00159432	University of Southern California\|Hoffmann-La Roche\|Genentech, Inc.	Colorectal Cancer	February 2005	Phase 2
NCT00124566	Eisai Inc.	Prostate Cancer	June 2004	Phase 2
NCT03802591	CStone Pharmaceuticals	Gastric Adenocarcinoma\|Gastroesophageal Junction Adenocarcinoma	March 28, 2019	Phase 3
NCT05201859	Sun Yat-sen University	Nasopharyngeal Carcinoma	March 29, 2022	Phase 2
NCT01869192	University of Colorado, Denver	Malignant Neoplasm of Female Breast	March 5, 2003	Phase 2
NCT00789958	Southwest Oncology Group\|National Cancer Institute (NCI)	Extrahepatic Bile Duct Cancer\|Gallbladder Cancer	December 2008	Phase 2
NCT04420871	The Affiliated Hospital of Qingdao University	Patient Participation	December 10, 2018	Phase 1
NCT05052437	Beijing Biostar Technologies, Ltd\|Chengdu Biostar Pharmaceuticals, Ltd	Advanced and Metastatic Breast Cancer	October 22, 2020	Phase 1
NCT00700570	Hoffmann-La Roche	Colorectal Cancer	August 2008	Phase 2
NCT05227131	MedSIR\|MacroGenics\|Seagen Inc.	Metastatic Breast Cancer\|Advanced Breast Cancer\|HER2-positive Breast Cancer	May 15, 2022	Phase 2
NCT00338988	M.D. Anderson Cancer Center\|Sanofi-Synthelabo	Cancer of the Gallbladder\|Cancer of the Biliary Tract	August 2003	Phase 2
NCT02940925	Sun Yat-sen University	Nasopharyngeal Carcinoma	September 2016	Phase 3
NCT02170090	Universitätsklinikum Hamburg-Eppendorf\|Deutsche Krebshilfe e.V., Bonn (Germany)\|Cancer Research UK\|Australasian Gastro-Intestinal Trials Group\|Dutch Cancer Society	Cholangiocarcinoma\|Gall Bladder Carcinoma	April 2014	Phase 3
NCT01158274	National Cancer Institute (NCI)	Adult Grade III Lymphomatoid Granulomatosis\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|AIDS-related Diffuse Large Cell Lymphoma\|AIDS-related Diffuse Mixed Cell Lymphoma\|AIDS-related Diffuse Small Cleaved Cell Lymphoma\|AIDS-related Immunoblastic Large Cell Lymphoma\|AIDS-related Lymphoblastic Lymphoma\|AIDS-related Peripheral+Systemic Lymphoma\|AIDS-related Primary CNS Lymphoma\|AIDS-related Small Noncleaved Cell Lymphoma\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Cutaneous B-cell Non-Hodgkin Lymphoma\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|HER2-negative Breast Cancer\|HIV-associated Hodgkin Lymphoma\|Intraocular Lymphoma\|Male Breast Cancer\|Nodal Marginal Zone B-cell Lymphoma\|Post-transplant Lymphoproliferative Disorder\|Primary Central Nervous System Hodgkin Lymphoma\|Primary Central Nervous System Non-Hodgkin Lymphoma\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Breast Cancer\|Recurrent Colon Cancer\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Rectal Cancer\|Recurrent Small Lymphocytic Lymphoma\|Small Intestine Lymphoma\|Splenic Marginal Zone Lymphoma\|Stage III Adult Burkitt Lymphoma\|Stage III Adult Diffuse Large Cell Lymphoma\|Stage III Adult Diffuse Mixed Cell Lymphoma\|Stage III Adult Diffuse Small Cleaved Cell Lymphoma\|Stage III Adult Hodgkin Lymphoma\|Stage III Adult Immunoblastic Large Cell Lymphoma\|Stage III Adult Lymphoblastic Lymphoma\|Stage III Adult T-cell Leukemia+Lymphoma\|Stage III Colon Cancer\|Stage III Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage III Grade 1 Follicular Lymphoma\|Stage III Grade 2 Follicular Lymphoma\|Stage III Grade 3 Follicular Lymphoma\|Stage III Mantle Cell Lymphoma\|Stage III Marginal Zone Lymphoma\|Stage III Mycosis Fungoides+Sezary Syndrome\|Stage III Rectal Cancer\|Stage III Small Lymphocytic Lymphoma\|Stage IIIA Breast Cancer\|Stage IIIB Breast Cancer\|Stage IIIC Breast Cancer\|Stage IV Adult Burkitt Lymphoma\|Stage IV Adult Diffuse Large Cell Lymphoma\|Stage IV Adult Diffuse Mixed Cell Lymphoma\|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma\|Stage IV Adult Hodgkin Lymphoma\|Stage IV Adult Immunoblastic Large Cell Lymphoma\|Stage IV Adult Lymphoblastic Lymphoma\|Stage IV Adult T-cell Leukemia+Lymphoma\|Stage IV Breast Cancer\|Stage IV Colon Cancer\|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage IV Grade 1 Follicular Lymphoma\|Stage IV Grade 2 Follicular Lymphoma\|Stage IV Grade 3 Follicular Lymphoma\|Stage IV Mantle Cell Lymphoma\|Stage IV Marginal Zone Lymphoma\|Stage IV Mycosis Fungoides+Sezary Syndrome\|Stage IV Rectal Cancer\|Stage IV Small Lymphocytic Lymphoma\|Unspecified Adult Solid Tumor, Protocol Specific\|Waldenström Macroglobulinemia	June 2010	Phase 1
NCT01588990	Hoffmann-La Roche	Colorectal Neoplasms	June 26, 2012	Phase 4
NCT01494662	Dana-Farber Cancer Institute\|Translational Breast Cancer Research Consortium\|Puma Biotechnology, Inc.	Breast Cancer	February 2012	Phase 2
NCT05512520	Sun Yat-sen University	Metastatic Esophageal Squamous Cell Carcinoma	September 20, 2022	Phase 2
NCT04389073	Cancer Institute and Hospital, Chinese Academy of Medical Sciences\|Beijing Huanxing Cancer Hospital	Metastatic Breast Cancer	April 1, 2020	Phase 2
NCT05415917	Rutgers, The State University of New Jersey	Pancreatic Cancer	July 29, 2022	Phase 2
NCT00678535	Merck KGaA, Darmstadt, Germany	Gastric Cancer	June 2008	Phase 3
NCT04276493	BeiGene	Breast Cancer\|Gastric Cancer\|Gastroesophageal Junction Cancer	March 26, 2020	Phase 1\|Phase 2
NCT00042965	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Kidney Cancer	October 2002	Phase 2
NCT01048580	AEterna Zentaris\|SCRI Development Innovations, LLC	Colon Cancer	October 2009	Phase 1
NCT01630083	Astellas Pharma Global Development, Inc.\|Astellas Pharma Inc	CLDN18.2-positive Adenocarcinoma of the Gastroesophageal Junction\|CLDN18.2-positive Adenocarcinoma of Esophagus\|CLDN18.2-positive Gastric Adenocarcinoma	July 19, 2012	Phase 2
NCT01572324	Peking University	Biliary Tract Cancer	March 2012	Phase 2
NCT04582968	Fudan University	Breast Cancer\|Brain Metastases\|HER2-positive Breast Cancer	September 1, 2019	Phase 1\|Phase 2
NCT00191438	Eli Lilly and Company	Breast Neoplasms	October 2002	Phase 3
NCT04428151	Merck Sharp & Dohme LLC\|Eisai Inc.	Squamous Cell Carcinoma of Head and Neck	August 6, 2020	Phase 2
NCT00779454	Vejle Hospital	Cholangiocarcinoma	September 2008	Phase 2
NCT00196820	German Breast Group\|Hoffmann-La Roche	Breast Cancer	July 2005	Phase 2
NCT00019773	National Cancer Institute (NCI)	Carcinoma of the Appendix\|Colorectal Cancer\|Small Intestine Cancer	July 1999	Phase 1
NCT02864849	Peking University Cancer Hospital & Institute	Rectal Cancer	August 2016	Phase 2
NCT01238029	Sponsor GmbH\|iOMEDICO AG\|Arbeitsgemeinschaft fur Internistische Onkologie\|Arbeitskreis Klinische Studien\|GlaxoSmithKline	Metastatic Breast Cancer\|HER2 Positive\|First or Second Line Therapy\|Failure or Contraindication of Trastuzumab Therapy	October 2010	Phase 1
NCT00354224	Medical University of South Carolina	Gastric Cancer	January 2005	Phase 2
NCT03889626	Fudan University	Stomach Neoplasms\|Gastrointestinal Neoplasms\|Stomach Diseases\|Digestive System Neoplasms\|Capecitabine\|Apatinib\|Neoplasms\|Molecular Mechanisms of Pharmacological Action	March 22, 2019	Phase 3
NCT00623805	Hoffmann-La Roche	Colorectal Cancer	March 2008	Phase 3
NCT00068588	National Cancer Institute (NCI)	Male Breast Cancer\|Recurrent Breast Cancer\|Stage IV Breast Cancer	October 2003	Phase 2
NCT02505750	Centre Antoine Lacassagne\|Centre de Haute Energie\|Centre Azuréen de Cancérologie\|Hôpital de la Croix-Rousse\|Institut Paoli-Calmettes\|Hôpital de la Timone\|Centre de radiothérapie Bayard\|Centre Oncologie Radiothérapie de Mâcon\|Centre Leon Berard\|Hospices Civils de Lyon\|Clinique Charcot\|Institut de Cancérologie Lucien Neuwirth\|The Clatterbridge Cancer Centre NHS Foundation Trust\|Spire Hull and East Riding Hospital\|Nottingham University Hospitals NHS Trust\|Royal Surrey County Hospital NHS Foundation Trust\|Uppsala University Hospital\|Karolinska Institutet\|Aarhus University Hospital	Rectal Neoplasms	June 24, 2015	Phase 3
NCT01710592	Cancer Trials Ireland	Gastro Oesophageal Cancer	May 2007	Phase 2
NCT00811993	Hoffmann-La Roche	Neoplasms	February 2009	Phase 1
NCT00442637	Dutch Colorectal Cancer Group\|Koningin Wilhelmina Fonds\|Sanofi\|Hoffmann-La Roche	Colorectal Cancer Metastatic	January 2007	Phase 3
NCT00538291	City of Hope Medical Center\|National Cancer Institute (NCI)	Colorectal Cancer	August 2005	Phase 2
NCT02669173	Case Comprehensive Cancer Center	Glioblastoma	October 11, 2016	Phase 1
NCT02735239	Ludwig Institute for Cancer Research\|AstraZeneca	Esophageal Cancer	June 24, 2016	Phase 1\|Phase 2
NCT00156975	Arbeitsgruppe Lebermetastasen und Tumoren	Colorectal Neoplasms\|Liver Metastases	November 2004	Phase 3
NCT03082053	Aslan Pharmaceuticals	Advanced or Metastatic Biliary Tract Cancer\|Advanced or Metastatic Solid Tumors	January 31, 2017	Phase 1
NCT04963088	The First Affiliated Hospital with Nanjing Medical University	Gastric Cancer	March 6, 2021	Phase 1\|Phase 2
NCT02494583	Merck Sharp & Dohme LLC	Gastric Adenocarcinoma	July 31, 2015	Phase 3
NCT01941966	Instituto do Cancer do Estado de São Paulo	Anal Canal Cancer.	November 2010	Phase 2
NCT04639986	Everest Medicines\|Iqvia Pty Ltd\|Medidata Solutions\|Parexel	Metastatic Breast Cancer	November 23, 2020	Phase 3
NCT00146588	Craig A. Bunnell, MD, MPH\|Dana-Farber Cancer Institute\|Massachusetts General Hospital\|Brigham and Women´s Hospital\|Beth Israel Deaconess Medical Center\|Pharmacia	Breast Cancer\|Stage I Breast Cancer\|Stage II Breast Cancer\|Stage IIIA Breast Cancer	April 2002	Not Applicable
NCT00039390	National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	April 2002	Phase 1
NCT03358004	Mario Negri Institute for Pharmacological Research	Triple Negative Breast Cancer	June 14, 2017	Phase 2
NCT00165217	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital	Colorectal Adenocarcinoma	November 2001	Phase 2
NCT02954055	ETOP IBCSG Partners Foundation	Breast Cancer	September 13, 2017	Phase 2
NCT05131893	National Institute of Oncology, Hungary	Breast Cancer	March 2022
NCT01880658	Sun Yat-sen University	Colorectal Neoplasms	June 2013	Phase 2
NCT01671891	Fudan University	Rectal Cancer	February 2012
NCT00382720	Sanofi	Stomach Neoplasms	September 2006	Phase 2
NCT03487666	Georgetown University\|Bristol-Myers Squibb	Triple Negative Breast Cancer	May 21, 2018	Phase 2
NCT00203411	Translational Oncology Research International\|Genentech, Inc.	Colorectal Cancer	March 2006	Phase 2
NCT02352831	Washington University School of Medicine	Pancreatic Cancer\|Cancer of Pancreas\|Cancer of the Pancreas\|Pancreas Cancer	August 31, 2015	Phase 1\|Phase 2
NCT02958111	Sun Yat-sen University\|Tongji Hospital\|Wuhan Union Hospital, China\|Peking University\|Air Force Military Medical University, China\|Second Affiliated Hospital of Soochow University\|West China Hospital\|The First Affiliated Hospital of Guangdong Pharmaceutical University\|First People´s Hospital of Foshan\|Fifth Affiliated Hospital, Sun Yat-Sen University\|Cancer Hospital of Guizhou Province\|Xiangya Hospital of Central South University\|First Affiliated Hospital of Zhejiang University\|Jilin Provincial Tumor Hospital\|Henan Cancer Hospital\|Hunan Cancer Hospital\|The First Affiliated Hospital of Xiamen University\|Cancer Hospital of Guangxi Medical University	Nasopharyngeal Carcinoma	January 2017	Phase 3
NCT03387592	Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori	Neuroendocrine Carcinoma	March 6, 2017	Phase 2
NCT01060007	Washington University School of Medicine	Rectal Neoplasms	November 2009	Phase 2
NCT04159142	Hebei Medical University Fourth Hospital\|Beijing 302 Hospital\|CSPC Ouyi Pharmaceutical Co., Ltd.	Triple Negative Breast Cancer\|Nab-paclitaxel	November 20, 2019	Phase 2
NCT00049660	European Organisation for Research and Treatment of Cancer - EORTC	Breast Cancer	September 2002	Phase 2\|Phase 3
NCT01471847	Novartis Pharmaceuticals\|Novartis	Locally Advance Breast Cancer (LABC)\|Metastatic Breast Cancer (MBC)	February 2012	Phase 1
NCT00383695	Royal Marsden NHS Foundation Trust	Colorectal Cancer	September 2005	Phase 2
NCT01396668	Seoul National University Hospital	Pancreatic Cancer	December 2004	Phase 2
NCT03775525	Genzada Pharmaceuticals USA, Inc.\|Translational Drug Development	Advanced Cancer\|Gastric Cancer\|Breast Cancer\|Pancreatic Cancer\|Prostate Cancer Metastatic\|Colo-rectal Cancer\|Solid Tumor\|Solid Carcinoma\|Solid Carcinoma of Stomach\|Cancer of Stomach\|Lymphoma\|Sarcoma\|Cutaneous T Cell Lymphoma\|Head and Neck Squamous Cell Carcinoma\|Basal Cell Carcinoma\|Cutaneous T-cell Lymphoma\|Cutaneous Squamous Cell Carcinoma	March 1, 2019	Phase 1
NCT00909402	Bristol-Myers Squibb\|Exelixis	Stomach Neoplasms\|Esophageal Neoplasms	November 2009	Phase 1
NCT02935309	H. Lee Moffitt Cancer Center and Research Institute	Rectal Cancer\|Rectal Adenocarcinoma	October 14, 2016	Phase 1
NCT00169000	Dartmouth-Hitchcock Medical Center\|Hoffmann-La Roche	Metastatic Breast Cancer	January 2003	Phase 1
NCT01423604	Incyte Corporation	Pancreatic Cancer	July 2011	Phase 2
NCT03399110	Fudan University	Gastric Cancer	December 1, 2017	Phase 3
NCT02473094	University of Campinas, Brazil	Rectal Neoplasms\|Adenocarcinoma\|Carcinoma	July 2015	Phase 2
NCT00885066	Centre Antoine Lacassagne	Pancreatic Cancer	May 2008	Phase 1
NCT02115152	Guangxi Medical University	Stage II Breast Cancer\|Stage III Breast Cancer	June 2014	Phase 2
NCT00657137	Tragara Pharmaceuticals, Inc.	Breast Cancer	April 2008	Phase 2
NCT02861300	David Bajor\|Case Comprehensive Cancer Center	Colorectal Cancer\|Colon Cancer\|Rectal Cancer\|Solid Tumor	September 12, 2016	Phase 1\|Phase 2
NCT01130805	Samsung Medical Center	Gastric Cancer	December 2010	Phase 2
NCT00006108	UNC Lineberger Comprehensive Cancer Center\|National Cancer Institute (NCI)	Breast Cancer	August 1999	Phase 1\|Phase 2
NCT01517009	Jeroen Bosch Ziekenhuis\|Eindhoven Cancer Registry	Gastric Cancer	June 2008	Phase 2
NCT01941641	Chinese University of Hong Kong	Rectal Cancer	October 9, 2013	Phase 2
NCT00121134	Harold J. Burstein, MD, PhD\|Genentech, Inc.\|Beth Israel Deaconess Medical Center\|Indiana University School of Medicine\|University of California, San Francisco\|University of North Carolina\|Dana-Farber Cancer Institute	Breast Cancer	June 2005	Not Applicable
NCT01196455	Croatian Cooperative Group for Clinical Research in Oncology\|Roche Pharma AG	Breast Cancer\|Metastasis	March 2006	Phase 2
NCT01836432	NewLink Genetics Corporation\|Lumos Pharma	Pancreatic Cancer\|Pancreatic Carcinoma Non-resectable\|Locally Advanced Malignant Neoplasm	May 2013	Phase 3
NCT00100815	Roswell Park Cancer Institute	Pancreatic Cancer	August 2004	Phase 2
NCT00123851	Dana-Farber Cancer Institute\|Sanofi-Synthelabo\|OSI Pharmaceuticals\|Hoffmann-La Roche\|Genentech, Inc.\|Massachusetts General Hospital\|Beth Israel Deaconess Medical Center	Colorectal Cancer\|Neoplasm Metastasis	March 2003	Phase 2
NCT04250948	Sun Yat-sen University\|Shanghai Junshi Bioscience Co., Ltd.	Gastric Cancer\|Locally Advanced Solid Tumor	October 12, 2019	Phase 2
NCT00868998	Columbia University	Biliary Cancer	August 2005	Phase 2
NCT00033540	Southwest Oncology Group\|National Cancer Institute (NCI)	Extrahepatic Bile Duct Cancer\|Gallbladder Cancer	September 2003	Phase 2
NCT01268384	Asan Medical Center	Pancreatic Cancer	April 2006	Phase 2
NCT04782804	Fudan University	Cholangiocarcinoma, Intrahepatic	January 1, 2021	Phase 1\|Phase 2
NCT01161186	University of California, San Francisco\|Celgene Corporation	Pancreatic Neoplasms\|Pancreatic Cancer\|Adenocarcinoma	July 2010	Phase 1
NCT02460419	Sun Yat-sen University\|Affiliated Cancer Hospital & Institute of Guangzhou Medical University\|Affiliated Cancer Hospital of Shantou University Medical College	Nasopharyngeal Carcinoma	April 2015	Phase 3
NCT00022698	Hoffmann-La Roche	Colorectal Cancer	May 2001	Phase 2
NCT05314998	John Neoptolemos\|Molecular Health GmbH\|Deutsches Krebsforschungszentrum (DKFZ)\|Nationales Centrum für Tumorerkrankungen\|Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest\|Institut für Medizinische Biometrie\|Heidelberg University	Pancreatic Ductal Adenocarcinoma	November 1, 2022	Phase 3
NCT00155259	National Taiwan University Hospital	Breast Cancer	October 2004	Phase 2
NCT02780700	Boehringer Ingelheim	Colorectal Neoplasms	July 5, 2016	Phase 2
NCT01007552	Roswell Park Cancer Institute\|Genentech, Inc.	Cholangiocarcinoma	December 2009	Phase 2
NCT04844385	Sun Yat-sen University	Esophageal Squamous Cell Carcinoma	February 20, 2021	Phase 2
NCT00959946	Pfizer	Advanced Breast Cancer (Parts 1 and 2)\|Advanced Pancreatic Cancer (Part 1)\|Advanced Colorectal Cancer (Part 1)\|Advanced Cholangiocarcinoma (Part 1)\|Advanced Glioblastoma Multiforme (Part 1)	September 2009	Phase 1\|Phase 2
NCT00675012	AGC Biologics S.p.A.	Colon Cancer	December 2007	Phase 2
NCT05494190	Eye & ENT Hospital of Fudan University\|Shandong Provincial Hospital\|Harbin Medical University Third Affiliated Hospital	Hypopharyngeal Carcinoma	October 2022	Not Applicable
NCT00069121	Hoffmann-La Roche	Colorectal Cancer	April 18, 2003	Phase 3
NCT05236972	Sun Yat-sen University\|Second Affiliated Hospital, School of Medicine, Zhejiang University\|West China Hospital	Colorectal Carcinoma	January 1, 2022	Phase 3
NCT04185649	Bio-Thera Solutions	HER2-positive Advanced Breast Cancer	July 1, 2018	Phase 3
NCT05009069	Hoffmann-La Roche	Rectal Neoplasms\|Rectal Cancer	March 18, 2022	Phase 2
NCT02919878	King Faisal Specialist Hospital & Research Center	Rectal Adenocarcinoma	December 2014	Phase 2
NCT01924819	Australasian Gastro-Intestinal Trials Group\|National Health and Medical Research Council, Australia\|Trans Tasman Radiation Oncology Group\|European Organisation for Research and Treatment of Cancer - EORTC\|NCIC Clinical Trials Group	Gastric Cancer	September 2009	Phase 2\|Phase 3
NCT00309556	Austrian Breast & Colorectal Cancer Study Group\|Amgen\|Ebewe Pharma GmbH\|Hoffmann-La Roche\|Sanofi	Breast Cancer	February 2005	Phase 3
NCT01191697	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital\|Genentech, Inc.	Esophageal Cancer\|Gastric Cancer	February 2011	Phase 2
NCT00214864	Cancer Research Network\|Hoffmann-La Roche	Metastatic Breast Cancer	December 2002	Phase 2
NCT00156312	University of Michigan Rogel Cancer Center	Breast Cancer	July 2003	Not Applicable
NCT03515941	Tannaz Armaghany\|Baylor College of Medicine	Gastrointestinal Cancer	June 22, 2018	Early Phase 1
NCT01203306	University of Turin, Italy	Neuroendocrine Carcinomas	January 2006	Phase 2
NCT00048126	Hoffmann-La Roche	Colorectal Cancer	July 2001	Phase 2
NCT00215644	Merck KGaA, Darmstadt, Germany	Esophageal Cancer\|Gastric Cancer	August 31, 2005	Phase 2
NCT00003704	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Cancer	April 1999	Phase 1
NCT03231176	Aslan Pharmaceuticals	Biliary Tract Cancer	December 19, 2017	Phase 2
NCT00215982	H. Lee Moffitt Cancer Center and Research Institute\|Roche Pharma AG	Colorectal Cancer	December 2004	Phase 2
NCT04301557	Sun Yat-sen University	DMMR Colorectal Cancer\|MSI-H Colorectal Cancer\|Locally Advanced Colorectal Cancer	July 31, 2020	Phase 2
NCT01924078	Fudan University	Breast Cancer	October 2010	Phase 2
NCT02395640	Fudan University	Gastric Cancer	March 2015	Phase 3
NCT02794571	Genentech, Inc.	Advanced+Metastatic Tumors	May 23, 2016	Phase 1
NCT01151761	Stanford University	Cholangiocarcinoma\|Hepatobiliary Neoplasm\|Liver Cancer\|Bile Duct Cancer\|Cancer of Gallbladder	January 2011	Phase 2
NCT00669370	University of Turku\|Sanofi	Stomach Neoplasms	June 2006	Phase 2
NCT02558959	Zhejiang University	Biliary Tract Neoplasms	September 1, 2015	Phase 2
NCT05321329	Fondazione IRCCS Istituto Nazionale dei Tumori, Milano	Pseudomyxoma Peritonei	December 3, 2018	Phase 2
NCT01962246	Hebei Medical University	Gastroesophageal Junction Adenocarcinoma	February 2012	Phase 2\|Phase 3
NCT02119663	Incyte Corporation	Pancreatic Cancer	June 2014	Phase 3
NCT04080843	Zhejiang University\|Chia Tai Tianqing Pharmaceutical Group Co., Ltd.	Colorectal Cancer\|RAS and BRAF Wild-type\|Colorectal Neoplasms\|Intestinal Neoplasms\|Gastrointestinal Neoplasms\|Digestive System Neoplasms\|Neoplasms by Site\|Neoplasms\|Digestive System Diseases\|Gastrointestinal Diseases\|Colonic Diseases\|Intestinal Diseases\|Rectal Diseases	November 15, 2019	Phase 2
NCT00216086	Gabi Chiorean, MD\|Pfizer\|Roche Pharma AG\|Walther Cancer Institute\|Hoosier Cancer Research Network	Rectal Cancer	May 2005	Phase 2
NCT03093870	Aslan Pharmaceuticals\|bioRASI, LLC\|CMIC Co, Ltd. Japan\|Syneos Health	Biliary Tract Cancer	July 4, 2017	Phase 2\|Phase 3
NCT02338245	Aslan Pharmaceuticals	Metastatic Breast Cancer	December 29, 2014	Phase 2
NCT00089479	Hoffmann-La Roche	Breast Cancer	August 2002	Phase 3
NCT03500380	RemeGen Co., Ltd.	Breast Neoplasms\|Breast Diseases\|Capecitabine\|HER2-positive Breast Cancer\|HER2 Positive Breast Carcinoma\|HER2-positive Advanced Breast With Liver Metastases	April 24, 2018	Phase 2\|Phase 3
NCT02121405	Zhejiang University	Colorectal Neoplasm\|Effects of Radiation Therapy\|Effects of Chemotherapy\|Surgery	October 2015	Phase 3
NCT04849364	Bryan Schneider, MD\|Genentech, Inc.\|Pfizer\|Foundation Medicine\|Indiana University\|Epic Sciences\|Vera Bradley Foundation for Breast Cancer Research\|Hoosier Cancer Research Network	Breast Cancer\|Triple Negative Breast Cancer	August 24, 2021	Phase 2
NCT00353262	Hoffmann-La Roche	Colorectal Cancer	July 2005	Phase 1
NCT03817268	The First Affiliated Hospital of Anhui Medical University	Gastric Cancer	January 16, 2019	Phase 3
NCT00430027	University of Colorado, Denver\|Bristol-Myers Squibb\|Sanofi	Esophageal Adenocarcinoma	November 2006	Not Applicable
NCT02688712	Providence Health & Services\|Eli Lilly and Company	Rectal Adenocarcinoma	March 24, 2016	Phase 2
NCT00148122	University of Michigan Rogel Cancer Center	Head and Neck Cancer	November 2002	Phase 2
NCT00869258	Columbia University	Pancreatic Cancer Stage IVA	June 2005	Phase 2
NCT01017822	Radiation Therapy Oncology Group\|National Cancer Institute (NCI)	Pancreatic Cancer		Phase 1\|Phase 2
NCT01323530	Eisai Limited\|Eisai Inc.	Metastatic Breast Cancer	January 26, 2010	Phase 1\|Phase 2
NCT00390676	Adherex Technologies, Inc.\|US Oncology Research	Neoplasms	November 2006	Phase 1
NCT01308190	Corporacion Parc Tauli\|Fundación Olga Torres	Rectal Cancer	August 2010	Phase 3
NCT03132025	Yanqiao Zhang\|Harbin Medical University	Metastatic Colorectal Cancer	April 30, 2017	Phase 2
NCT04220203	Seagen Inc.\|Parexel	HER2-positive Breast Cancer
NCT04337658	Second Affiliated Hospital, School of Medicine, Zhejiang University	HER2-positive Breast Cancer	July 1, 2020	Phase 3
NCT01300962	UNC Lineberger Comprehensive Cancer Center\|Novartis Pharmaceuticals	Metastatic Breast Cancer	August 2011	Phase 1
NCT03462251	iOMEDICO AG\|Novartis Pharmaceuticals	Breast Cancer\|Hormone Receptor Positive Tumor\|HER 2 Negative Breast Cancer	May 24, 2018	Phase 3
NCT02955940	Incyte Corporation	Pancreatic Cancer\|Colorectal Cancer (CRC)\|Breast Cancer\|Lung Cancer	November 30, 2016	Phase 2
NCT01234402	Eli Lilly and Company	Breast Cancer	March 2011	Phase 2
NCT05093907	BeyondBio Inc.	Metastatic Colorectal Cancer	August 31, 2021	Phase 1\|Phase 2
NCT03507465	Guangdong Provincial People´s Hospital	Breast Cancer	November 29, 2017	Phase 2\|Phase 3
NCT00634725	GERCOR - Multidisciplinary Oncology Cooperative Group	Pancreatic Cancer	February 2008	Phase 3
NCT04245865	Vejle Hospital	Colorectal Cancer Metastatic	June 26, 2020	Phase 2
NCT04494425	AstraZeneca\|Daiichi Sankyo Company, Limited 3-5-1 Nihonbashihoncho, Chuo-ku, Tokyo	Advanced or Metastatic Breast Cancer	July 24, 2020	Phase 3
NCT03469557	BeiGene	Esophageal Squamous Cell Carcinoma, Gastric Carcinoma, Gastroesophageal Junction Carcinoma	July 18, 2017	Phase 2
NCT04495088	Ralf Hofheinz\|Deutsche Krebshilfe e.V., Bonn (Germany)\|Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest\|German Rectal Cancer Study Group\|Universitätsmedizin Mannheim	Rectal Cancer	September 30, 2020	Phase 3
NCT02846428	Hoffmann-La Roche	Breast Cancer	March 2004	Phase 2
NCT00114231	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Colorectal Cancer	May 2006	Phase 2
NCT04405206	Peking University Cancer Hospital & Institute	Rectum Cancer	May 25, 2020
NCT02422199	Jiangsu HengRui Medicine Co., Ltd.	HER2 Positive Metastatic Breast Cancer	May 2015	Phase 1\|Phase 2
NCT00408408	NSABP Foundation Inc\|National Cancer Institute (NCI)	Breast Cancer	November 2006	Phase 3
NCT04227041	Qingdao Zhixin Health Technology Co., Ltd.\|The Affiliated Hospital of Qingdao University	HER-2 Positive Colorectal Cancer	January 10, 2020	Phase 1\|Phase 2
NCT00005649	Hoffmann-La Roche	Breast Cancer	July 1998	Phase 2
NCT04661150	Hoffmann-La Roche	Gastric Cancer\|Gastroesophageal Junction Adenocarcinoma	March 12, 2021	Phase 2
NCT04296240	Peking University Cancer Hospital & Institute	Rectal Cancer	March 1, 2019	Phase 2
NCT01939054	Cancer Institute and Hospital, Chinese Academy of Medical Sciences\|Biotech Pharmaceutical Co., Ltd.	Breast Cancer	September 2013	Phase 2
NCT01132664	Novartis Pharmaceuticals\|Novartis	Metastatic Breast Cancer\|HER2&addition; Breast Cancer	May 2010	Phase 1\|Phase 2
NCT00585078	Beth Israel Deaconess Medical Center\|Sanofi\|Dana-Farber Cancer Institute	Pancreatic Cancer	May 2004	Phase 2
NCT00464295	Aga Khan University	Carcinoma, Hepatocellular	August 2006	Phase 2
NCT01549795	Azienda Ospedaliera di Padova	Hilar Cholangiocarcinoma\|Primary Sclerosing Cholangitis	January 2012	Not Applicable
NCT02024607	Sumitomo Pharma Oncology, Inc.	Advanced Gastrointestinal Cancer	January 2014	Phase 1\|Phase 2
NCT03167164	ImmunityBio, Inc.	Merkel Cell Carcinoma	December 2017	Phase 1\|Phase 2
NCT01633203	Grupo Oncologico Cooperativo Chileno de Investigation	Gastric Cancer	August 2010
NCT00191152	Eli Lilly and Company	Breast Cancer\|Breast Neoplasms\|Cancer of the Breast	February 2002	Phase 3
NCT00373113	Pfizer	Breast Neoplasms	November 2006	Phase 3
NCT04135313	Blokhin´s Russian Cancer Research Center	Rectal Neoplasms Malignant\|Rectum Carcinoma\|Rectal Cancer	October 20, 2019	Phase 3
NCT05002686	Ruijin Hospital	Gastric Cancer	August 7, 2021	Phase 2\|Phase 3
NCT01131078	Hoffmann-La Roche	Colorectal Cancer	June 2005	Phase 2
NCT03958721	A Bapsi Chakravarthy, MD\|Vanderbilt-Ingram Cancer Center	Resistant Breast Cancer\|Non-metastatic Invasive Breast Cancer	July 18, 2019	Phase 1
NCT01061515	Washington University School of Medicine	Carcinoma	May 10, 2011	Phase 1
NCT02025036	The First Affiliated Hospital of Henan University of Science and Technology\|Luoyang Central Hospital\|Military 150 Hospital\|Anyang Cancer Hospital\|Nanyang Central Hospital\|Henan Oncology Hospital\|The First Affiliated Hospital of Xinyang Medical College\|Sanmenxia Central Hospital	Stage III Esophageal Squamous Cell Carcinoma\|Stage II Esophageal Squamous Cell Carcinoma	October 2014	Phase 3
NCT00433589	European Organisation for Research and Treatment of Cancer - EORTC\|Agendia\|Breast International Group\|Roche Pharma AG\|Novartis\|Sanofi	Breast Cancer	February 2007	Phase 3
NCT03377387	Memorial Sloan Kettering Cancer Center\|Puma Biotechnology, Inc.	Breast Cancer	December 13, 2017	Phase 1\|Phase 2
NCT03813641	Shenzhen People´s Hospital	Colorectal Cancer	January 28, 2019	Phase 2
NCT01845337	University of Edinburgh\|NHS Lothian	Gastrointestinal Cancer\|Cancer of Unknown Primary Site\|Pancreatic Cancer\|Bile Duct Neoplasms	February 5, 2014	Phase 2
NCT01891227	Arbeitsgemeinschaft medikamentoese Tumortherapie	Breast Cancer	August 9, 2013	Phase 2
NCT04302441	Fudan University	Breast Cancer	November 10, 2016	Phase 2
NCT04882241	Merck Sharp & Dohme LLC	Gastric Cancer\|Gastroesophageal Junction Cancer	July 29, 2020	Phase 3
NCT01759238	Universitätsklinikum Hamburg-Eppendorf	Colorectal Cancer\|Metastases	May 2013	Phase 2
NCT00268151	University of Louisville\|James Graham Brown Cancer Center\|Sanofi	Carcinoma, Non-Small Cell Lung	February 2005	Phase 1
NCT01349088	Sidney Kimmel Cancer Center at Thomas Jefferson University\|Susan G. Komen Breast Cancer Foundation\|Amgen\|Thomas Jefferson University	Breast Cancer\|Metastatic Breast Cancer\|Stage IV Breast Cancer	December 2013	Phase 1\|Phase 2
NCT02119026	Prof. Dr. Werner Scheithauer\|Medical University of Vienna	Metastatic Colorectal Cancer	February 2011	Phase 2
NCT02603159	The First Affiliated Hospital of Henan University of Science and Technology	Stage III Esophageal Squamous Cell Carcinoma\|Stage II Esophageal Squamous Cell Carcinoma	October 2014	Phase 3
NCT05216653	Sir Run Run Shaw Hospital	MSS Locally Advanced Rectal Adenocarcinoma	April 7, 2022	Phase 2
NCT04566380	Ono Pharmaceutical Co. Ltd	Pan-tumor	September 10, 2020	Phase 2
NCT00568022	R-Pharm	Breast Cancer	February 2008	Phase 1
NCT02563054	Hoffmann-La Roche	Gastric Cancer	April 2003	Phase 3
NCT04769050	Fudan University	Breast Cancer	February 18, 2021
NCT03853707	City of Hope Medical Center\|National Cancer Institute (NCI)	Anatomic Stage IV Breast Cancer AJCC v8\|Metastatic Triple-Negative Breast Carcinoma\|Prognostic Stage IV Breast Cancer AJCC v8	March 4, 2019	Phase 1\|Phase 2
NCT01077986	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	Metastatic Pancreatic Cancer	August 2009	Phase 1\|Phase 2
NCT04679597	Institute of Oncology Ljubljana	Rectal Cancer	January 1, 2016
NCT00327743	Sanofi	Breast Cancer\|Cancer	August 2006	Phase 1\|Phase 2
NCT01044433	Abramson Cancer Center of the University of Pennsylvania	Head and Neck Cancer\|Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma\|Recurrent Metastatic Squamous Neck Cancer With Occult Primary\|Recurrent Salivary Gland Cancer\|Recurrent Squamous Cell Carcinoma of the Hypopharynx\|Recurrent Squamous Cell Carcinoma of the Larynx\|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity\|Recurrent Squamous Cell Carcinoma of the Oropharynx\|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity\|Recurrent Verrucous Carcinoma of the Larynx\|Recurrent Verrucous Carcinoma of the Oral Cavity\|Salivary Gland Squamous Cell Carcinoma\|Stage IV Salivary Gland Cancer\|Stage IV Squamous Cell Carcinoma of the Hypopharynx\|Stage IV Squamous Cell Carcinoma of the Larynx\|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity\|Stage IV Squamous Cell Carcinoma of the Oropharynx\|Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity\|Stage IV Verrucous Carcinoma of the Larynx\|Stage IV Verrucous Carcinoma of the Oral Cavity	October 2009	Phase 2
NCT03916510	University of Oxford\|PsiOxus Therapeutics Ltd\|Cancer Research UK	Locally Advanced Rectal Cancer	July 1, 2019	Phase 1
NCT05585814	Shanghai Changzheng Hospital	Locally Advanced Colorectal Cancer	October 2022	Phase 2
NCT02004769	Sun Yat-sen University\|Fudan University\|307 Hospital of PLA\|Shandong Tumor Hospital\|Tongji Hospital\|West China Hospital\|Shandong Provincial Hospital\|Second Affiliated Hospital of Suzhou University\|Tianjin Medical University General Hospital\|Second Affiliated Hospital, School of Medicine, Zhejiang University\|Sixth Affiliated Hospital, Sun Yat-sen University\|Nanfang Hospital of Southern Medical University	Stomach Neoplasms\|Neoplasms Metastasis\|ERBB2 Gene Amplification	November 2013	Phase 2
NCT00483405	UNC Lineberger Comprehensive Cancer Center\|Sanofi\|Roche Pharma AG\|Bristol-Myers Squibb\|National Center for Research Resources (NCRR)\|National Cancer Institute (NCI)	Liver Cancer	October 2006	Phase 2
NCT04753879	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|Merck Sharp & Dohme LLC	Metastatic Pancreatic Cancer	September 29, 2021	Phase 2
NCT04034251	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Gastric Adenocarcinoma\|Gastric Cancer\|Esophagogastric Junction\|Peritoneal Carcinomatosis	June 9, 2020	Phase 2
NCT00159445	University of Southern California\|Eli Lilly and Company	Colorectal Cancer\|Colon Cancer	March 2004	Phase 2
NCT00630890	University of California, San Francisco	Cholangiocarcinoma\|Klatskin Tumor\|Biliary Tract Cancer	October 2007	Phase 1
NCT01506167	Hoffmann-La Roche	Colorectal Cancer	July 6, 2012
NCT05016869	Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Metastatic Colorectal Cancer	April 12, 2022	Phase 1\|Phase 2
NCT01322152	Fudan University	Colorectal Cancer	March 2011	Phase 2
NCT05163223	Aston Sci. Inc.	Breast Cancer	February 28, 2022	Phase 2
NCT00082095	Johnson & Johnson Pharmaceutical Research & Development, L.L.C.\|Tibotec Therapeutics, a Division of Ortho Biotech Products, L.P., USA	Metastatic Breast Cancer	April 2004	Phase 3
NCT02830139	Wuhan University	Malignant Neoplasm of Colorectum	July 2016	Phase 2
NCT04012918	Ain Shams University	Metastatic Breast Cancer	August 30, 2018	Phase 2
NCT01718808	Swiss Group for Clinical Cancer Research	Metastatic Colorectal Cancer	November 2012	Phase 2
NCT03821454	Zhejiang Cancer Hospital	Breast Cancer	February 1, 2019	Not Applicable
NCT03383679	UNICANCER	Breast Cancer Female\|Triple Negative and Androgen Receptor Positive	March 14, 2018	Phase 2
NCT02656589	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University\|Sun Yat-sen University\|Huiping Li,M.D., Ph.D.,Peking University Cancer Hospital	Breast Cancer	June 2015
NCT02253459	Beijing Biostar Technologies, Ltd	Breast Cancer	August 2014	Phase 3
NCT00408772	University of California, Davis\|Sanofi	Colorectal Cancer\|Metastatic Cancer	June 2007	Phase 2
NCT04411537	Fudan University	Locally Advanced Rectal Cancer	July 1, 2020	Phase 2
NCT00047710	M.D. Anderson Cancer Center\|Genentech, Inc.	Pancreatic Cancer	September 2002	Phase 1
NCT00301925	Institute of Cancer Research, United Kingdom	Breast Cancer	December 16, 2005	Phase 3
NCT00081224	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Colorectal Cancer	December 2004	Phase 2
NCT00842686	Institute of Oncology Ljubljana	Locally Advanced Rectal Cancer	January 2009	Phase 2
NCT03907475	National Cancer Institute (NCI)	Locally Advanced Malignant Solid Neoplasm\|Metastatic Malignant Solid Neoplasm\|Unresectable Malignant Solid Neoplasm	June 25, 2019	Phase 2
NCT03300609	University of Southern California\|National Cancer Institute (NCI)\|Amgen	Colorectal Adenocarcinoma\|RAS Wild Type\|Stage III Colorectal Cancer AJCC v7\|Stage IIIA Colorectal Cancer AJCC v7\|Stage IIIB Colorectal Cancer AJCC v7\|Stage IIIC Colorectal Cancer AJCC v7\|Stage IV Colorectal Cancer AJCC v7\|Stage IVA Colorectal Cancer AJCC v7\|Stage IVB Colorectal Cancer AJCC v7	February 27, 2018	Phase 3
NCT02250209	Chinese PLA General Hospital	Gastric Cancer	July 2014	Phase 2
NCT03167177	ImmunityBio, Inc.	Melanoma	December 2017	Phase 1\|Phase 2
NCT02798510	Fudan University	Malignant Neoplasm Other Gallbladder+Extrahepatic Bile Duct	April 2016	Phase 3
NCT03169790	ImmunityBio, Inc.	Non Hodgkin Lymphoma	December 2017	Phase 1\|Phase 2
NCT01233505	National Cancer Institute (NCI)	Adenocarcinoma of the Pancreas\|Adenocarcinoma of the Stomach\|BRCA1 Mutation Carrier\|BRCA2 Mutation Carrier\|Ovarian Mucinous Cystadenocarcinoma\|Recurrent Breast Cancer\|Recurrent Colon Cancer\|Recurrent Gastric Cancer\|Recurrent Ovarian Epithelial Cancer\|Recurrent Ovarian Germ Cell Tumor\|Recurrent Pancreatic Cancer\|Recurrent Rectal Cancer\|Stage IA Breast Cancer\|Stage IB Breast Cancer\|Stage II Breast Cancer\|Stage IIIA Breast Cancer\|Stage IIIB Breast Cancer\|Stage IIIC Breast Cancer\|Stage IV Breast Cancer\|Stage IV Colon Cancer\|Stage IV Gastric Cancer\|Stage IV Ovarian Epithelial Cancer\|Stage IV Ovarian Germ Cell Tumor\|Stage IV Pancreatic Cancer\|Stage IV Rectal Cancer\|Unspecified Adult Solid Tumor, Protocol Specific	October 2010	Phase 1
NCT02005549	Hoffmann-La Roche	Breast Cancer	February 2006	Phase 2
NCT02743221	Institut de Recherches Internationales Servier\|ADIR, a Servier Group company\|Servier	Metastatic Colorectal Cancer	April 29, 2016	Phase 2
NCT04895358	Merck Sharp & Dohme LLC	Breast Neoplasms	June 18, 2021	Phase 3
NCT00985556	Yonsei University\|National Cancer Institute (NCI)	Gastric Cancer	January 2009	Phase 2
NCT01386346	Weill Medical College of Cornell University\|Celgene Corporation	Esophageal Cancer\|Malignant Neoplasm of Cardio-esophageal Junction of Stomach	June 2011	Phase 1
NCT00574171	University of Wisconsin, Madison\|GlaxoSmithKline	Metastatic Colorectal Cancer	September 2007	Phase 2
NCT05064085	H. Lee Moffitt Cancer Center and Research Institute\|Regeneron Pharmaceuticals	Hormone Receptor-positive Breast Cancer	October 12, 2021	Phase 1
NCT03792269	The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School	Colorectal Cancer Metastatic\|Chemotherapy Effect\|Chemotherapeutic Toxicity	January 1, 2016	Phase 2
NCT03638648	Zhejiang Cancer Hospital	Breast Cancer	November 1, 2019	Phase 2
NCT00122291	Alberta Health services\|AHS Cancer Control Alberta	Rectal Cancer\|Neoplasm Metastasis	January 2002	Phase 2
NCT00054457	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Esophageal Cancer\|Gastric Cancer	September 2003	Phase 2
NCT00484939	Hoffmann-La Roche	Colorectal Cancer	July 2007	Phase 3
NCT02838238	Peking Union Medical College Hospital	Breast Cancer	January 2014	Phase 2
NCT05247905	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Metastatic Pancreatic Neuroendocrine Tumor\|Unresectable Pancreatic Neuroendocrine Carcinoma	March 16, 2022	Phase 2
NCT00226941	George Albert Fisher\|Bristol-Myers Squibb\|Stanford University	Rectal Cancer\|Colo-rectal Cancer	June 2004	Phase 1\|Phase 2
NCT01280643	Fox Chase Cancer Center\|National Cancer Institute (NCI)	Metastatic Colorectal Cancer	March 2010	Not Applicable
NCT03387111	ImmunityBio, Inc.	Squamous Cell Carcinoma	January 13, 2018	Phase 1\|Phase 2
NCT04751955	Korean Cancer Study Group	Colorectal Cancer Metastatic	January 1, 2022	Phase 1\|Phase 2
NCT04518280	Fudan University	Locally Advanced Rectal Cancer	May 1, 2021	Phase 2
NCT03152370	Adlai Nortye Biopharma Co., Ltd.	Neoadjuvant Therapy in Rectal Cancer	May 17, 2017	Phase 1
NCT00194779	University of Washington\|National Cancer Institute (NCI)	Estrogen Receptor-negative Breast Cancer\|Estrogen Receptor-positive Breast Cancer\|HER2-positive Breast Cancer\|Progesterone Receptor-negative Breast Cancer\|Progesterone Receptor-positive Breast Cancer\|Stage IA Breast Cancer\|Stage IB Breast Cancer\|Stage II Breast Cancer\|Stage IIIA Breast Cancer	October 2003	Phase 2
NCT00749450	Cancer Research UK, Glasgow	Colorectal Cancer	March 2008	Phase 3
NCT02316535	West China Hospital	Colorectal Neoplasms	November 2014	Phase 3
NCT04394598	Fudan University	Locally Advanced Rectal Cancer	March 1, 2020	Phase 2
NCT03745170	Innovent Biologics (Suzhou) Co. Ltd.	Gastric Cancer	December 19, 2018	Phase 3
NCT04166318	ECOG-ACRIN Cancer Research Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Anal Basaloid Carcinoma\|Anal Canal Cloacogenic Carcinoma\|Anal Canal Squamous Cell Carcinoma\|Anal Margin Squamous Cell Carcinoma\|Stage I Anal Cancer AJCC v8\|Stage IIA Anal Cancer AJCC v8	November 12, 2019	Phase 2
NCT04355858	Fudan University	Breast Cancer\|Metastatic Cancer	May 1, 2020	Phase 2
NCT01609127	Genta Incorporated	Locally Advanced Non-resectable Breast Cancer\|Metastatic Breast Cancer	May 2012	Phase 2
NCT04933227	Hoffmann-La Roche	Stomach Neoplasms\|Gastric Cancer\|Gastroesophageal Junction Adenocarcinoma	August 6, 2021	Phase 2
NCT00148720	Dana-Farber Cancer Institute\|Hoffmann-La Roche\|Beth Israel Deaconess Medical Center\|Brigham and Women´s Hospital	Invasive Breast Carcinoma\|Primary Invasive Breast Cancer\|Stage I Breast Cancer\|Stage II Breast Cancer\|Stage III Breast Cancer	September 2004	Phase 2
NCT01952951	National Cancer Center, Korea\|Korean Cancer Study Group	Rectal Neoplasms\|Adenocarcinoma	June 2014	Phase 2
NCT03702985	Fudan University	Locally Advanced Rectal Cancer	May 28, 2018	Phase 2
NCT04733963	Second Affiliated Hospital, School of Medicine, Zhejiang University	Colorectal Cancer	March 1, 2021	Phase 2
NCT00741260	Puma Biotechnology, Inc.	Breast Cancer	December 9, 2008	Phase 1\|Phase 2
NCT00256321	University of California, Irvine\|Sanofi-Synthelabo	Gastric Carcinoma\|Gastroesophageal Junction Carcinoma	October 2004	Phase 2
NCT02978612	Oslo University Hospital	Colon Cancer	June 2016	Phase 2
NCT00680901	Novartis Pharmaceuticals\|Novartis	Neoplasms, Gastrointestinal Tract	June 4, 2008	Phase 3
NCT00881816	Nanjing Sike Pharmaceutical Co., Ltd.	Advanced Gastric Carcinoma	April 2009	Phase 1
NCT04456699	Merck Sharp & Dohme LLC	Metastatic Colorectal Cancer	August 19, 2020	Phase 3
NCT03371017	Hoffmann-La Roche	Triple Negative Breast Neoplasms	January 11, 2018	Phase 3
NCT01077739	Hoffmann-La Roche	Colorectal Cancer	July 2009	Phase 2
NCT05553522	Baptist Health South Florida\|Seagen Inc.	Brain Metastases\|HER2-positive Breast Cancer	October 2022	Phase 1
NCT00335959	Southwest Oncology Group\|National Cancer Institute (NCI)	Gastric Cancer	May 2006	Phase 2
NCT04246502	Shandong Cancer Hospital and Institute	Metastatic Breast Cancer	January 2020	Phase 2
NCT02872116	Bristol-Myers Squibb\|Ono Pharmaceutical Co. Ltd	Gastric Cancer\|Gastroesophageal Junction Cancer\|Esophageal Adenocarcinoma	October 12, 2016	Phase 3
NCT03586869	ImmunityBio, Inc.	Pancreatic Cancer	July 28, 2018	Phase 1\|Phase 2
NCT00609336	University of Washington\|National Cancer Institute (NCI)	Adenocarcinoma of the Pancreas\|Stage IA Pancreatic Cancer\|Stage IB Pancreatic Cancer\|Stage IIA Pancreatic Cancer\|Stage IIB Pancreatic Cancer	January 2008	Phase 2
NCT02574455	Gilead Sciences	Breast Cancer	November 7, 2017	Phase 3
NCT00496587	M.D. Anderson Cancer Center\|Eli Lilly and Company	Renal Cell Carcinoma\|Kidney Cancer	July 2007	Phase 2
NCT04789096	Breast Cancer Trials, Australia and New Zealand	Breast Cancer\|HER2-positive Breast Cancer	December 2022	Phase 2
NCT00613080	Radiation Therapy Oncology Group\|National Cancer Institute (NCI)\|NRG Oncology	Colorectal Cancer	April 2008	Phase 2
NCT03950271	Henan Cancer Hospital	Gastric Cancer	January 21, 2020	Phase 2
NCT01722162	Washington University School of Medicine	Colorectal Neoplasms	April 2013	Phase 2
NCT02716766	The University of Hong Kong	Carcinoma, Hepatocellular\|Secondary	March 2016	Phase 2
NCT05254847	Fudan University	Biliary Tract Cancer	December 30, 2021	Phase 2
NCT05609370	BeiGene	Unresectable or Metastatic Microsatellite Stable+Mismatch Repair Proficient Colorectal Cancer	November 2022	Phase 1\|Phase 2
NCT01135498	Hoffmann-La Roche	Colorectal Cancer	November 2006	Phase 2
NCT01097018	AEterna Zentaris	Colorectal Cancer	April 2010	Phase 3
NCT04720131	Beijing Friendship Hospital	Biliary Tract Cancer\|Programmed Cell Death 1 Ligand 1 Gene Mutation\|Targeted Molecular Therapy\|Capecitabine	February 1, 2021	Phase 2
NCT01729923	University of Washington\|National Cancer Institute (NCI)	Recurrent Colon Carcinoma\|Recurrent Rectal Carcinoma\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer	March 2013	Phase 2
NCT02921256	National Cancer Institute (NCI)\|NRG Oncology	Rectal Adenocarcinoma\|Stage II Rectal Cancer AJCC v7\|Stage III Rectal Cancer AJCC v7	October 12, 2016	Phase 2
NCT00816868	Sun Yat-sen University	Non-small Cell Lung Cancer	January 2009	Phase 2
NCT00130533	Spanish Breast Cancer Research Group\|Hoffmann-La Roche\|IBEROAMERICAN COALITION FOR BREAST ONCOLOGY RESEARCH (CIBOMA)	Breast Cancer	January 2006	Phase 3
NCT05007106	Merck Sharp & Dohme LLC	Uterine Cervical Neoplasms\|Endometrial Neoplasms\|Squamous Cell Carcinoma of Head and Neck\|Gallbladder Neoplasms\|Cholangiocarcinoma\|Esophageal Neoplasms\|Triple Negative Breast Neoplasms\|Hepatocellular Carcinoma\|Urinary Bladder Neoplasms\|Ovarian Neoplasms\|Stomach Neoplasms	September 16, 2021	Phase 2
NCT00425360	Royal Liverpool University Hospital\|National Cancer Institute (NCI)	Pancreatic Cancer	September 2006	Phase 3
NCT02754011	UNICANCER\|Novartis	Breast Cancer	February 2, 2017	Phase 1
NCT01150630	IRCCS San Raffaele	Pancreatic Cancer	May 2010	Phase 2
NCT00314353	NSABP Foundation Inc\|Genentech, Inc.\|Hoffmann-La Roche\|International Drug Development Institute	Colorectal Neoplasms	March 2006	Phase 2
NCT00559676	Centre Hospital Regional Universitaire de Limoges\|National Cancer Institute (NCI)	Colorectal Cancer	March 2005	Phase 4
NCT05411380	wang shusen\|Sun Yat-sen University	Breast Cancer	October 3, 2022	Phase 2
NCT04768426	Stanford University	Triple Negative Breast Cancer\|Breast Cancer	February 3, 2021	Phase 2
NCT03615326	Merck Sharp & Dohme LLC	Gastric Neoplasms\|Gastroesophageal Junction Adenocarcinoma	October 5, 2018	Phase 3
NCT00316420	Swedish Medical Center\|Roche Pharma AG	Pancreatic Cancer	December 2003	Phase 1
NCT04068103	NRG Oncology\|National Cancer Institute (NCI)	Colon Adenocarcinoma\|Stage IIA Colon Cancer AJCC v8	December 16, 2019	Phase 2\|Phase 3
NCT01748773	Hoffmann-La Roche	Gastric Cancer\|Gastroesophageal Junction Cancer	January 29, 2013	Phase 2
NCT04132713	First Affiliated Hospital of Harbin Medical University\|Sponsor GmbH	Microbiota	September 10, 2019
NCT00659022	Radboud University Medical Center	Colorectal Neoplasms\|Liver Neoplasms	July 2008	Phase 2
NCT02314117	Eli Lilly and Company	Metastatic Gastric Adenocarcinoma\|Gastroesophageal Junction Adenocarcinoma	January 20, 2015	Phase 3
NCT03828227	GERCOR - Multidisciplinary Oncology Cooperative Group	Elderly Patients\|Metastatic Colorectal Cancer\|Quality of Life	June 7, 2019	Phase 3
NCT00697502	National University Hospital, Singapore	Solid Tumors	May 2007	Phase 1
NCT01655992	Fudan University	Metastatic Breast Cancer	January 2012	Phase 3
NCT00602082	Cambridge University Hospitals NHS Foundation Trust\|National Cancer Institute (NCI)	Gastrointestinal Carcinoid Tumor\|Islet Cell Tumor	August 2005	Phase 2
NCT00967655	Loma Linda Oncology Medical Group, Inc.\|National Cancer Institute (NCI)	Colorectal Cancer	July 2009	Phase 2
NCT01843725	Jules Bordet Institute	Metastatic Colorectal Cancers\|Metastatic Gastric Cancers\|Metastatic Oesophageal Cancers\|Metastatic Pancreatic Cancers\|Metastatic Biliary Cancers\|Metastatic Breast Cancers	September 2013	Phase 1
NCT00104689	UNICANCER	Colorectal Cancer	June 30, 2003	Phase 2
NCT02445391	ECOG-ACRIN Cancer Research Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Estrogen Receptor Negative\|HER2+Neu Negative\|Invasive Breast Carcinoma\|Progesterone Receptor Negative\|Stage II Breast Cancer\|Stage IIA Breast Cancer\|Stage IIB Breast Cancer\|Stage III Breast Cancer\|Stage IIIA Breast Cancer\|Stage IIIB Breast Cancer\|Stage IIIC Breast Cancer\|Triple-Negative Breast Carcinoma	April 29, 2015	Phase 3
NCT00541112	UNICANCER	Colorectal Cancer	October 29, 2007	Phase 2
NCT04753203	Korean Cancer Study Group	Metastatic Colorectal Cancer\|PIK3CA Gene Mutation	February 28, 2021	Phase 1\|Phase 2
NCT03959150	Ruijin Hospital	Pancreatic Cancer	January 5, 2020	Phase 2\|Phase 3
NCT00891878	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Adenocarcinoma of the Gastroesophageal Junction\|Esophageal Cancer	August 2009	Phase 2
NCT00744640	University Hospital, Basel, Switzerland\|Swiss National Science Foundation\|Swiss Cancer League\|Roche Pharma AG\|Sanofi	Locally Advanced Pancreatic Cancer\|Metastatic Pancreatic Cancer	October 2005	Phase 1\|Phase 2
NCT00811135	Hoffmann-La Roche	Breast Cancer	December 2008	Phase 2
NCT00254137	Ludwig-Maximilians - University of Munich\|Merck Sharp & Dohme LLC\|Sanofi\|Pfizer\|Hoffmann-La Roche	Metastatic Colorectal Cancer	September 2004	Phase 2
NCT00005839	City of Hope Medical Center\|National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	August 2000	Phase 1
NCT05489211	AstraZeneca\|Daiichi Sankyo, Inc.	Endometrial Cancer\|Gastric Cancer\|Metastatic Castration-resistant Prostate Cancer\|Ovarian Cancer\|Colorectal Cancer	September 6, 2022	Phase 2
NCT01584544	Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Rectal Neoplasms	January 2011	Phase 1
NCT00084734	Roswell Park Cancer Institute\|National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	May 2002	Phase 1
NCT05290194	Fifth Affiliated Hospital, Sun Yat-Sen University	Radiotherapy\|PD-1 Inhibitor\|Capecitabine\|Nasopharyngeal Carcinoma	March 28, 2022	Phase 2
NCT00266799	Merck Sharp & Dohme LLC\|Essex Pharma GmbH	Breast Cancer	January 13, 2006	Phase 3
NCT00114179	National Cancer Institute (NCI)\|NRG Oncology	Adenocarcinoma of the Pancreas\|Stage II Pancreatic Cancer\|Stage III Pancreatic Cancer	January 2005	Phase 2
NCT00568529	Fudan University	Gastric Cancer	October 2007	Phase 2
NCT01824875	ECOG-ACRIN Cancer Research Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Gastrinoma\|Glucagonoma\|Insulinoma\|Islet Cell Carcinoma\|Pancreatic Polypeptide Tumor\|Recurrent Islet Cell Carcinoma\|Somatostatinoma	April 11, 2013	Phase 2
NCT00124527	Eisai Inc.	Thyroid Cancer	March 31, 2005	Phase 2
NCT00114816	Finnish Breast Cancer Group\|Hoffmann-La Roche\|Sanofi\|AstraZeneca	Breast Cancer	January 2004	Phase 3
NCT03451370	Istituto Oncologico Veneto IRCCS	Elderly Metastatic Colorectal Cancer Patients	November 1, 2017
NCT00613145	SCRI Development Innovations, LLC\|Bayer	Refractory Malignancy	February 2008	Phase 1
NCT01308086	Hellenic Oncology Research Group\|University Hospital of Crete	CRC	October 2010	Phase 3
NCT00227747	UNICANCER	Colorectal Cancer	November 8, 2005	Phase 3
NCT01493336	Hoffmann-La Roche	Breast Cancer, Colorectal Cancer	May 2012	Phase 1
NCT02717923	Huazhong University of Science and Technology\|The First Affiliated Hospital of Nanchang University\|Hunan Cancer Hospital\|Henan Cancer Hospital	Colorectal Neoplasms	January 2014	Phase 2
NCT00929240	Hoffmann-La Roche	Breast Cancer	July 2009	Phase 3
NCT00030732	Swiss Group for Clinical Cancer Research\|Central European Cooperative Oncology Group	Pancreatic Cancer	June 2001	Phase 3
NCT05212454	Second Affiliated Hospital, School of Medicine, Zhejiang University	Breast Cancer\|Chemotherapy Effect	January 2023	Phase 3
NCT00555620	Pfizer	Stomach Neoplasms	May 2008	Phase 1
NCT03817411	Taizhou EOC Pharma Co., Ltd.\|Shanghai East Hospital\|Shanghai Zhongshan Hospital	Gastric Cancer	January 25, 2019	Phase 2
NCT04390958	Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Esophageal Squamous Cell Carcinoma	May 15, 2020	Phase 2
NCT01589419	AbbVie (prior sponsor, Abbott)\|AbbVie	Locally Advanced Rectal Cancer	June 2012	Phase 1
NCT00504660	M.D. Anderson Cancer Center	Anaplastic Glioma of Brain\|Glioblastoma Multiforme\|Brain Cancer	September 2003	Phase 2
NCT03854799	Gruppo Oncologico del Nord-Ovest	Colon Rectal Cancer	April 1, 2019	Phase 2
NCT00303927	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|National Cancer Institute (NCI)	Pancreatic Cancer	December 2005	Phase 2
NCT00433550	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)\|Pfizer\|Sanofi	Small Intestine Adenocarcinoma\|Recurrent Small Intestine Cancer	May 2007	Phase 2
NCT02767752	Herlev Hospital\|GENIS	Pancreatic Cancer	November 2016	Phase 2
NCT02361112	Jiangsu HengRui Medicine Co., Ltd.\|Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Metastatic Breast Cancer	August 2014	Phase 1
NCT02625610	EMD Serono Research & Development Institute, Inc.\|Merck KGaA, Darmstadt, Germany\|EMD Serono	Unresectable, Locally Advanced or Metastatic, Adenocarcinoma of the Stomach, or of the Gastro Esophageal Junction	December 24, 2015	Phase 3
NCT01332604	Genentech, Inc.	Solid Cancers	July 2011	Phase 1
NCT04809142	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.	Advanced Biliary Cancer	February 4, 2021	Phase 3
NCT00227734	Swiss Group for Clinical Cancer Research	Colorectal Cancer	June 2004	Phase 2
NCT00417209	Sanofi	Pancreatic Neoplasms	December 2006	Phase 3
NCT05417386	Colin D. Weekes, M.D.\|Novartis\|Massachusetts General Hospital	Pancreas Cancer\|Metastatic Pancreatic Cancer\|Metastatic Pancreatic Adenocarcinoma	August 9, 2022	Phase 1
NCT00263029	Sanofi	Rectal Neoplasms	June 2002	Phase 2
NCT00473005	Stanford University\|Novartis	Breast Cancer	August 2007	Phase 1
NCT04965064	University of Rochester	Breast Cancer	September 23, 2022	Phase 2
NCT05265208	Center Eugene Marquis	Resectable Intrahepatic Cholangiocarcinoma	February 4, 2022	Phase 2
NCT00277069	University of New Mexico	Breast\|Cancer	May 2000	Phase 1\|Phase 2
NCT00216021	Hoosier Cancer Research Network\|Sanofi\|Hoffmann-La Roche\|Walther Cancer Institute	Metastatic Breast Cancer	March 2004	Phase 2
NCT00251186	University of Medicine and Dentistry of New Jersey\|Rutgers Cancer Institute of New Jersey\|Bristol-Myers Squibb\|Rutgers, The State University of New Jersey	Colorectal Cancer	April 2006	Phase 2
NCT03678649	Zhejiang Cancer Hospital	Head and Neck Neoplasms	September 10, 2018	Phase 2
NCT00675194	Johannes Gutenberg University Mainz	Gastric Cancer	October 2003	Phase 2
NCT00958737	GERCOR - Multidisciplinary Oncology Cooperative Group	Colorectal Cancer	May 12, 2009	Phase 3
NCT04089150	Australasian Gastro-Intestinal Trials Group\|Trans Tasman Radiation Oncology Group\|Australian Government Department of Health and Ageing	Pancreatic Cancer	October 1, 2019	Phase 2
NCT00006812	Gynecologic Oncology Group\|National Cancer Institute (NCI)\|GOG Foundation	Ovarian Cancer\|Primary Peritoneal Cavity Cancer	March 2001	Phase 2
NCT00795678	Case Comprehensive Cancer Center\|United States Department of Defense\|National Cancer Institute (NCI)	Breast Cancer\|Metastatic Cancer	September 2008
NCT00967031	UNICANCER	Breast Cancer\|Metastatic Cancer	April 2009	Phase 2
NCT03523585	Daiichi Sankyo, Inc.\|Daiichi Sankyo Co., Ltd.\|AstraZeneca	Breast Cancer	August 1, 2018	Phase 3
NCT00031876	Swiss Group for Clinical Cancer Research	Breast Cancer	May 2000	Phase 1\|Phase 2
NCT00004187	Swiss Group for Clinical Cancer Research	Colorectal Cancer	June 1999	Phase 1\|Phase 2
NCT01234324	AIO-Studien-gGmbH\|Amgen\|WiSP Wissenschaftlicher Service Pharma GmbH	Stomach Neoplasms\|Gastroesophageal Junction Neoplasms	October 2010	Phase 2
NCT02581423	Hoffmann-La Roche	Colorectal Cancer	August 2005	Phase 4
NCT00551096	University of Colorado, Denver\|AstraZeneca	Malignant Solid Tumour\|Biliary Cancer\|Pancreatic Cancer	October 2007	Phase 1
NCT04621370	Liz-Anne Lewsley\|University of Glasgow\|AstraZeneca\|NHS Greater Glasgow and Clyde\|Cancer Research UK, Glasgow	Rectal Cancer\|Rectal Adenocarcinoma\|Rectal Neoplasms	December 7, 2020	Phase 2
NCT01846650	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.	Metastatic Breast Cancer or Metastatic Colorectal Cancer	December 2012	Phase 1
NCT03579758	Emory University	Stage I Gallbladder Cancer AJCC v8\|Stage II Gallbladder Cancer AJCC v8\|Stage IIA Gallbladder Cancer AJCC v8\|Stage IIB Gallbladder Cancer AJCC v8\|Stage III Gallbladder Cancer AJCC v8\|Stage IIIA Gallbladder Cancer AJCC v8\|Stage IIIB Gallbladder Cancer AJCC v8	April 3, 2019	Phase 3
NCT04911517	Beijing Friendship Hospital\|Hangzhou New Horizon Health Technology Co., Ltd.\|Beigene (Beijing) Biotechnology Co., Ltd\|Beijing Chao Yang Hospital\|Xuanwu Hospital, Beijing\|Tianjin Medical University General Hospital\|People´s Hospital of Tianjin\|Tianjin Medical University Cancer Institute & Hospital	Colorectal Neoplasms	June 1, 2021	Phase 2
NCT04646759	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Breast Cancer	October 14, 2020	Phase 3
NCT00226980	Stanford University\|Celgene Corporation	Kidney Neoplasms	October 2002	Phase 2
NCT00777101	Puma Biotechnology, Inc.	Advanced Breast Cancer\|Breast Cancer	February 4, 2009	Phase 2
NCT01725386	Hoffmann-La Roche	Breast Cancer	March 2011
NCT00064181	European Organisation for Research and Treatment of Cancer - EORTC	Colorectal Cancer	May 2003	Phase 3
NCT03852251	Akeso\|Akeso Pharmaceuticals, Inc.	Gastric Adenocarcinoma\|Advanced Solid Tumors\|Gastroesophageal Junction Adenocarcinoma	January 18, 2019	Phase 1\|Phase 2
NCT00821912	Karolinska University Hospital	Cancer of the Esophagus\|Gastric Cardia Carcinoma	March 2006	Phase 1\|Phase 2
NCT00580359	National Cancer Center, Korea	Stomach Neoplasms	May 2007	Phase 2
NCT02524275	University of Nebraska	Head and Neck Squamous Cell Carcinoma	March 30, 2015	Phase 2
NCT00950820	AIO-Studien-gGmbH\|iOMEDICO AG	Colorectal Neoplasms	September 2009	Phase 2
NCT00121251	National Cancer Institute (NCI)	Recurrent Renal Cell Carcinoma\|Stage III Renal Cell Cancer AJCC v7\|Stage IV Renal Cell Cancer AJCC v7	June 3, 2005	Phase 1\|Phase 2
NCT00858429	Northwestern University	Liver Cancer\|Metastatic Cancer	April 1, 2009	Phase 1
NCT03869892	Institut de Recherches Internationales Servier\|ADIR, a Servier Group company\|Servier	Metastatic Colorectal Cancer	March 21, 2019	Phase 3
NCT00278863	Asan Medical Center	Gastric Cancer	November 2004	Phase 2
NCT02576964	Hoffmann-La Roche	Carcinoma, Hepatocellular	January 2005	Phase 2
NCT04571437	Cairo University	Breast Cancer\|Estrogen Receptor-positive Breast Cancer\|Metastatic Breast Cancer	March 1, 2020	Phase 2
NCT01013740	Novartis Pharmaceuticals\|Novartis	Cancer	November 25, 2009	Phase 2
NCT00532714	National Cancer Center, Korea	Breast Cancer Metastatic	August 2006	Phase 2
NCT00548548	Genentech, Inc.\|Hoffmann-La Roche\|Chugai Pharmaceutical	Adenocarcinoma	September 2007	Phase 3
NCT02623153	Tianshu Liu\|Shanghai Zhongshan Hospital	Gastric Cancer	January 2016	Phase 2
NCT04703101	Jonsson Comprehensive Cancer Center	Locally Advanced Rectal Carcinoma\|Rectal Adenocarcinoma\|Stage II Rectal Cancer AJCC v8\|Stage IIA Rectal Cancer AJCC v8\|Stage IIB Rectal Cancer AJCC v8\|Stage IIC Rectal Cancer AJCC v8\|Stage III Rectal Cancer AJCC v8\|Stage IIIA Rectal Cancer AJCC v8\|Stage IIIB Rectal Cancer AJCC v8\|Stage IIIC Rectal Cancer AJCC v8	February 11, 2021	Phase 1
NCT05344742	CSPC ZhongQi Pharmaceutical Technology Co., Ltd.	Advanced Solid Tumor	April 2022	Phase 1
NCT00350961	Rigshospitalet, Denmark\|Henrik Jensen, Dept. of Oncology, Vejle Sygehus, Vejle, Denmark	Cholangiocarcinoma	June 2004	Phase 1\|Phase 2
NCT01501669	National Cancer Center, Korea\|Asan Medical Center\|Chung-Ang University\|Inha University Hospital\|Korea University Anam Hospital\|Samsung Medical Center\|Severance Hospital\|Seoul National University Hospital\|Seoul National University Bundang Hospital	Metastatic Breast Cancer	June 2011	Phase 3
NCT03169764	ImmunityBio, Inc.	Head and Neck Squamous Cell Carcinoma	December 2017	Phase 1\|Phase 2
NCT01558869	The University of Hong Kong	Pancreatic Adenocarcinoma	April 2012	Phase 2
NCT03756298	National Cancer Center, Korea	Triple Negative Breast Cancer	January 15, 2019	Phase 2
NCT00073905	Swiss Group for Clinical Cancer Research	Extrahepatic Bile Duct Cancer\|Gallbladder Cancer\|Liver Cancer\|Pain	April 2003	Phase 2
NCT04488159	Johannes Laengle, MD, PhD\|Medical University of Vienna	Colon Cancer Stage III	December 1, 2022	Phase 3
NCT02605265	Fudan University\|The First Affiliated Hospital with Nanjing Medical University\|Hubei Cancer Hospital\|First Affiliated Hospital of Chongqing Medical University\|Ruijin Hospital	Locally Advanced Rectal Cancer	October 2015	Phase 3
NCT04247984	Cancer Institute and Hospital, Chinese Academy of Medical Sciences\|Beijing Hospital\|Henan Cancer Hospital\|Liaoning Tumor Hospital & Institute\|Jiangsu Cancer Institute & Hospital	Metastatic Colorectal Cancer	May 1, 2018	Phase 2
NCT00882310	Columbia University	Pancreatic Cancer	September 2006	Phase 2
NCT01661972	John Strickler, M.D.\|Sanofi\|Duke University	Metastatic Colorectal Cancer	August 2012	Phase 1\|Phase 2
NCT00215501	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital	Solid Tumor	November 2001	Phase 1
NCT02860234	Peking University Cancer Hospital & Institute	Rectal Cancer	August 2016
NCT04339036	Abramson Cancer Center of the University of Pennsylvania\|Roswell Park Cancer Institute\|CARTI	Neuroendocrine Tumor Grade 2\|Neuroendocrine Tumors	October 7, 2021	Phase 2
NCT00069095	Hoffmann-La Roche	Colorectal Cancer	July 2003	Phase 3
NCT01702558	Hoffmann-La Roche	Breast Cancer\|Gastric Cancer	December 3, 2012	Phase 2
NCT01227707	Hoffmann-La Roche	Colorectal Cancer	November 2005	Phase 2
NCT03368131	Hebei Medical University	Gastroesophageal Junction Adenocarcinoma	December 1, 2017	Phase 2
NCT01070290	ArQule, Inc. (a wholly owned subsidiary of Merck Sharp and Dohme, a subsidiary of Merck & Co., Inc.)	Gastric Cancer		Phase 2
NCT00010023	NYU Langone Health\|National Cancer Institute (NCI)	Cancer	August 2000	Phase 1
NCT00397761	Medstar Health Research Institute	Breast Cancer	July 2006	Phase 2\|Phase 3
NCT03169738	ImmunityBio, Inc.	Non-small Cell Lung Cancer	February 2018	Phase 1\|Phase 2
NCT04158362	UNICANCER	Cancer Metastatic	June 11, 2020	Phase 3
NCT00600340	Central European Cooperative Oncology Group	Metastatic Breast Cancer	April 2008	Phase 3
NCT04662710	Merck Sharp & Dohme LLC\|Eisai Inc.	Advanced+Metastatic Gastroesophageal Adenocarcinoma	December 30, 2020	Phase 3
NCT02354612	Tracon Pharmaceuticals Inc.	Solid Tumors
NCT04008511	China Medical University, China\|Liaoning Tumor Hospital & Institute\|The First People´s Hospital of Jingzhou	Metastatic Colorectal Cancer	July 2019	Phase 1\|Phase 2
NCT04411524	Fudan University	Locally Advanced Rectal Cancer	July 1, 2020	Phase 2
NCT01917279	Binghe Xu\|Hoffmann-La Roche\|Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Breast Neoplasms\|Neoplasms by Site\|Neoplasm Metastasis\|Breast Diseases\|Skin Diseases	October 2013	Phase 3
NCT05091528	Silverback Therapeutics	HER2-positive Breast Cancer\|HER2-positive Gastric Cancer\|HER2-positive Colorectal Cancer\|HER2-expressing Non-small Cell Lung Cancer	February 8, 2022	Phase 1\|Phase 2
NCT01077726	Hoffmann-La Roche	Breast Cancer	January 2010	Phase 2
NCT04942626	Goethe University	Rectal Cancer	August 20, 2021	Phase 1
NCT01022541	Royal Marsden NHS Foundation Trust\|Roche Pharma AG	Metastatic Colorectal Cancer	June 2006	Phase 2
NCT03129074	Aslan Pharmaceuticals	Advanced or Metastatic Biliary Tract Cancer	May 2018	Phase 2
NCT00352378	National Cancer Center, Korea	Breast Cancer	June 2002	Phase 3
NCT02611960	Merck Sharp & Dohme LLC	Nasopharyngeal Neoplasms	April 18, 2016	Phase 3
NCT02114359	Seoul National University Hospital\|Ministry of Health & Welfare, Korea\|Korean Cancer Study Group	Gastric Cancer	February 2014	Phase 3
NCT02009449	Eli Lilly and Company\|ARMO BioSciences	Melanoma\|Prostate Cancer\|Ovarian Cancer\|Renal Cell Carcinoma\|Colorectal Carcinoma\|Pancreatic Carcinoma\|Non-small Cell Lung Carcinoma\|Solid Tumors\|Breast Cancer	November 15, 2013	Phase 1
NCT04522284	National University Hospital, Singapore\|The N.1 Institute for Health (N.1)	Solid Tumor	August 20, 2020	Phase 1\|Phase 2
NCT03175666	ImmunityBio, Inc.	Triple Negative Breast Cancer	December 2017	Phase 1\|Phase 2
NCT01013649	National Cancer Institute (NCI)\|NRG Oncology	Pancreatic Acinar Cell Carcinoma\|Pancreatic Ductal Adenocarcinoma\|Pancreatic Intraductal Papillary-Mucinous Neoplasm\|Stage I Pancreatic Cancer AJCC v6 and v7\|Stage IA Pancreatic Cancer AJCC v6 and v7\|Stage IB Pancreatic Cancer AJCC v6 and v7\|Stage II Pancreatic Cancer AJCC v6 and v7\|Stage IIA Pancreatic Cancer AJCC v6 and v7\|Stage IIB Pancreatic Cancer AJCC v6 and v7	November 17, 2009	Phase 3
NCT01935492	Borstkanker Onderzoek Groep\|Roche Pharma AG\|Teva Pharma	Human Epidermal Growth Factor 2 Negative Carcinoma of Breast\|Metastatic Breast Cancer	November 2010	Phase 3
NCT04304209	Sun Yat-sen University	Colorectal Cancer Stage II\|Colorectal Cancer Stage III\|Mmr Deficiency\|MSI-H	October 18, 2019	Phase 2\|Phase 3
NCT05535413	Hunan Cancer Hospital	Metastatic HER2 Negative Breast Carcinoma\|Brain Metastases\|Capecitabine\|UDT1	August 1, 2022	Phase 1\|Phase 2
NCT00291486	Ludwig Institute for Cancer Research\|National Cancer Institute (NCI)	Colorectal Neoplasms	October 2003	Phase 1
NCT01573468	Genta Incorporated	Gastric Carcinoma	April 2012	Phase 2
NCT04615013	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Cervical Esophagus Adenocarcinoma\|Clinical Stage II Esophageal Adenocarcinoma AJCC v8\|Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8\|Clinical Stage IIB Esophageal Adenocarcinoma AJCC v8\|Clinical Stage III Esophageal Adenocarcinoma AJCC v8\|Gastroesophageal Junction Adenocarcinoma\|Pathologic Stage II Esophageal Adenocarcinoma AJCC v8\|Pathologic Stage IIA Esophageal Adenocarcinoma AJCC v8\|Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8\|Pathologic Stage III Esophageal Adenocarcinoma AJCC v8\|Pathologic Stage IIIA Esophageal Adenocarcinoma AJCC v8\|Pathologic Stage IIIB Esophageal Adenocarcinoma AJCC v8\|Thoracic Esophagus Adenocarcinoma	November 23, 2020	Phase 1
NCT00645866	Mayo Clinic\|National Cancer Institute (NCI)	Breast Cancer	April 2003	Phase 2
NCT03764553	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)\|Servier	Esophageal Cancer	May 1, 2019	Phase 2
NCT00204776	University of Wisconsin, Madison\|Sanofi	Metastatic Breast Cancer	March 2005	Phase 2
NCT00142480	Massachusetts General Hospital\|Dana-Farber Cancer Institute\|Beth Israel Deaconess Medical Center\|Brigham and Women´s Hospital\|Genentech, Inc.\|Sanofi-Synthelabo\|Hoffmann-La Roche	Biliary Tract Cancer\|Gallbladder Adenocarcinoma	December 2004	Phase 2
NCT05438706	Fudan University	Triple-negative Breast Cancer	July 10, 2022	Phase 2
NCT00093808	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Breast Cancer	August 2004	Phase 2
NCT04550260	AstraZeneca	Esophageal Squamous Cell Carcinoma	October 19, 2020	Phase 3
NCT00604409	Fox Chase Cancer Center\|Sirtex Medical	Metastatic Liver Cancer	April 2006	Phase 1
NCT00196859	German Breast Group\|Hoffmann-La Roche\|AstraZeneca	Breast Cancer	June 2004	Phase 3
NCT00540800	National Cancer Institute, Naples	Breast Cancer	February 2004	Phase 3
NCT00039442	Gynecologic Oncology Group\|National Cancer Institute (NCI)\|GOG Foundation	Cervical Adenocarcinoma\|Cervical Adenosquamous Carcinoma\|Recurrent Cervical Carcinoma	April 29, 2002	Phase 2
NCT00201734	Ohio State University Comprehensive Cancer Center\|Roche Pharma AG	Tumors\|Unknown Primary Tumors\|Adenocarcinoma	June 2005	Phase 1\|Phase 2
NCT05608785	Henan Cancer Hospital	Gastric Cancer\|Gastroesophageal-junction Cancer	January 1, 2023	Phase 1\|Phase 2
NCT01918527	Vejle Hospital	Colon Cancer	September 2013	Phase 3
NCT00421824	Sanofi	Rectal Neoplasms	May 2006	Phase 2
NCT00129935	Spanish Breast Cancer Research Group\|Sanofi\|Hoffmann-La Roche\|Pfizer	Breast Cancer	February 2004	Phase 3
NCT01229813	Lund University Hospital\|Hoffmann-La Roche	Colorectal Cancer	October 2010	Phase 3
NCT04119622	Aiping Zhou\|Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Gastric Cancer Stage II\|Gastric Cancer Stage III	October 8, 2019	Phase 2
NCT03781362	Coordination Pharmaceuticals, Inc.	Advanced Tumors	December 21, 2018	Phase 1
NCT04854668	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.	Metastatic Colorectal Cancer	May 27, 2021	Phase 3
NCT02451553	University of Washington	Advanced Malignant Solid Neoplasm\|Bile Duct Carcinoma\|Recurrent Malignant Solid Neoplasm\|Recurrent Pancreatic Carcinoma\|Stage III Pancreatic Cancer AJCC v6 and v7\|Stage IVA Pancreatic Cancer\|Stage IVB Pancreatic Cancer	November 5, 2015	Phase 1
NCT02550743	howard safran\|Brown University\|Lifespan\|Novartis Pharmaceuticals Corporation (Financial supporter)	Rectal Cancer	June 3, 2016	Phase 1
NCT00887822	Hoffmann-La Roche	Gastric Cancer	March 2009	Phase 3
NCT01935778	Asan Medical Center\|Seoul National University Bundang Hospital\|Severance Hospital\|Inha University Hospital\|Hallym University Medical Center	Gastric Cancer, Adjuvant Chemotherapy, XO	September 2013	Phase 3
NCT04262804	Zai Lab (Shanghai) Co., Ltd.\|Zai Lab (Hong Kong), Ltd.	Breast Cancer Metastatic	January 13, 2020	Phase 2
NCT00093379	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Anal Cancer	April 2004	Phase 2
NCT01765582	Hoffmann-La Roche	Colorectal Neoplasms	January 23, 2013	Phase 2
NCT00726687	Alaunos Therapeutics	Advanced Solid Tumors	June 2008	Phase 1\|Phase 2
NCT05479240	Fujian Cancer Hospital	Immunotherapy	September 1, 2022	Phase 2
NCT00127933	Hoffmann-La Roche	Breast Cancer	August 2005	Phase 4
NCT01705106	University of Chicago\|National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	August 29, 2012	Phase 1
NCT00153881	Dartmouth-Hitchcock Medical Center\|Sanofi\|Hoffmann-La Roche	Esophageal Neoplasms	February 2000	Phase 1
NCT01996306	Epidemiological and Clinical Research Information Network	Colorectal Neoplasms\|Neoplasm Metastasis\|Intestinal Neoplasms\|Gastrointestinal Neoplasms\|Digestive System Neoplasms	December 2, 2013	Phase 3
NCT04443543	Fudan University	Rectal Cancer	June 22, 2020	Phase 2
NCT00288002	German Breast Group\|National Cancer Institute (NCI)	Breast Cancer	January 2005	Phase 3
NCT00508274	Novartis Pharmaceuticals\|Novartis	Neoplasms, Breast	July 18, 2007	Phase 3
NCT00439426	Hoffmann-La Roche	Nasopharyngeal Cancer	April 2007	Phase 2
NCT00854477	Cambridge University Hospitals NHS Foundation Trust	Pancreatic Adenocarcinoma	November 2009	Phase 4
NCT01231802	Adherex Technologies, Inc.	Metastatic Breast Cancer	April 2011	Phase 2
NCT00070434	Southwest Oncology Group\|National Cancer Institute (NCI)	Colorectal Cancer	August 2004	Phase 2
NCT00479856	GlaxoSmithKline	Relapsed Breast Cancer\|Neoplasms, Breast	November 2007	Phase 2
NCT03805399	Fudan University	Triple-negative Breast Cancer	October 18, 2018	Phase 1\|Phase 2
NCT03448835	The Netherlands Cancer Institute\|Hoffmann-La Roche	Stomach Cancer\|Gastro Esophageal Junction Cancer	March 7, 2018	Phase 2
NCT02120417	Incyte Corporation	Breast Cancer	May 2014	Phase 2
NCT02831179	Vanderbilt-Ingram Cancer Center\|National Cancer Institute (NCI)	Functional Pancreatic Neuroendocrine Tumor\|Malignant Somatostatinoma\|Merkel Cell Carcinoma\|Metastatic Adrenal Gland Pheochromocytoma\|Metastatic Carcinoid Tumor\|Multiple Endocrine Neoplasia Type 1\|Multiple Endocrine Neoplasia Type 2A\|Multiple Endocrine Neoplasia Type 2B\|Neuroendocrine Neoplasm\|Non-Functional Pancreatic Neuroendocrine Tumor\|Pancreatic Glucagonoma\|Pancreatic Insulinoma\|Recurrent Adrenal Cortex Carcinoma\|Recurrent Adrenal Gland Pheochromocytoma\|Recurrent Merkel Cell Carcinoma\|Somatostatin-Producing Neuroendocrine Tumor\|Stage III Adrenal Cortex Carcinoma\|Stage III Thyroid Gland Medullary Carcinoma\|Stage IIIA Merkel Cell Carcinoma\|Stage IIIB Merkel Cell Carcinoma\|Stage IV Adrenal Cortex Carcinoma\|Stage IV Merkel Cell Carcinoma\|Stage IVA Thyroid Gland Medullary Carcinoma\|Stage IVB Thyroid Gland Medullary Carcinoma\|Stage IVC Thyroid Gland Medullary Carcinoma\|Thymic Carcinoid Tumor\|VIP-Producing Neuroendocrine Tumor\|Well Differentiated Adrenal Cortex Carcinoma\|Zollinger Ellison Syndrome	December 2017	Phase 1
NCT02741856	Lisette Nixon\|Cancer Research UK\|Velindre NHS Trust	Oesophageal Cancer	November 4, 2016	Phase 2\|Phase 3
NCT01823679	Stanford University\|National Cancer Institute (NCI)	Squamous Cell Carcinoma of the Skin\|Recurrent Skin Cancer	March 2013	Phase 2
NCT02143388	Zhao Chong\|Jiangxi Provincial Cancer Hospital\|Cancer Institute and Hospital, Chinese Academy of Medical Sciences\|National Cancer Centre, Singapore\|Sun Yat-sen University	Local Advanced High Risk Nasopharyngeal Carcinoma	March 31, 2014	Phase 3
NCT03026803	City of Hope Medical Center\|Sanofi	Liver Cancer\|Hepatocellular Cancer	November 2006	Phase 2
NCT04595565	German Breast Group\|Gilead Sciences\|Austrian Breast & Colorectal Cancer Study Group\|Spanish Breast Cancer Research Group (GEICAM)\|ETOP IBCSG Partners Foundation\|Cancer Trials Ireland\|UNICANCER	HER2-negative Breast Cancer\|Triple Negative Breast Cancer	October 28, 2020	Phase 3
NCT00509561	Wales Cancer Trials Unit\|Cancer Research UK	Esophageal Cancer	February 2008	Phase 2\|Phase 3
NCT00427713	Cancer Research UK\|National Cancer Institute (NCI)	Colorectal Cancer	November 2004	Phase 3
NCT00107393	Tohoku University\|National Cancer Institute (NCI)	Breast Cancer	June 2003	Phase 2
NCT02371304	Amsterdam UMC, location VUmc	Rectal Cancer	October 2015	Phase 3
NCT00916578	M.D. Anderson Cancer Center	Breast Cancer	June 5, 2009	Phase 2
NCT02042443	National Cancer Institute (NCI)	Adult Cholangiocarcinoma\|Advanced Adult Hepatocellular Carcinoma\|BCLC Stage C Adult Hepatocellular Carcinoma\|BCLC Stage D Adult Hepatocellular Carcinoma\|Hilar Cholangiocarcinoma\|Localized Non-Resectable Adult Liver Carcinoma\|Recurrent Adult Liver Carcinoma\|Recurrent Childhood Liver Cancer\|Recurrent Extrahepatic Bile Duct Carcinoma\|Recurrent Gallbladder Carcinoma\|Stage II Gallbladder Cancer\|Stage III Childhood Hepatocellular Carcinoma\|Stage IIIA Gallbladder Cancer\|Stage IIIB Gallbladder Cancer\|Stage IV Childhood Hepatocellular Carcinoma\|Stage IV Distal Bile Duct Cancer\|Stage IVA Gallbladder Cancer\|Stage IVB Gallbladder Cancer\|Unresectable Extrahepatic Bile Duct Carcinoma	February 2014	Phase 2
NCT02529774	Ye Xu\|Fudan University	Resected Liver Metastases From Colorectal Cancer	September 2015	Phase 2\|Phase 3
NCT00842491	Peking University\|Xiansheng Pharmaceutical Company	Advanced Gastric Cancer	November 2008	Phase 2
NCT00437294	Eli Lilly and Company	Breast Cancer	March 2007	Phase 2
NCT00865982	Charite University, Berlin, Germany\|Roche Pharma AG\|Sanofi	Gastric Cancer\|Esophageal Cancer	September 2008	Phase 2
NCT02117479	Incyte Corporation	Pancreatic Cancer	March 2014	Phase 3
NCT01226732	SCRI Development Innovations, LLC\|Novartis Pharmaceuticals	Metastatic or Unresectable Solid Tumor Malignancy	November 2010	Phase 1
NCT00526669	GlaxoSmithKline	Neoplasms, Gastrointestinal Tract	March 2008	Phase 2
NCT00444678	NYU Langone Health\|Eli Lilly and Company\|Bristol-Myers Squibb	Colorectal Cancer\|Neoplasm Metastasis	June 1, 2004	Phase 2
NCT00281788	Duke University\|National Cancer Institute (NCI)	Esophageal Cancer	September 2003	Phase 1
NCT00081536	Aronex Pharmaceuticals	Colorectal Neoplasms		Phase 1\|Phase 2
NCT00482222	University of Southampton\|University Hospital Southampton NHS Foundation Trust	Colorectal Cancer\|Metastatic Cancer	February 2007	Phase 3
NCT02071043	Shanghai Zhongshan Hospital	Advanced Gastric Cancer	November 2008	Phase 2
NCT05144854	Ono Pharmaceutical Co. Ltd	Gastric Cancer	November 5, 2021	Phase 3
NCT00118755	Hoffmann-La Roche	Colorectal Cancer	July 2005	Phase 2
NCT02268006	Institute of Oncology Ljubljana	Rectal Carcinoma	January 2014	Phase 2
NCT02350686	Samsung Medical Center	Biliary Tract Cancer	May 14, 2015	Phase 2
NCT03197571	ImmunityBio, Inc.	Urothelial Carcinoma	December 2017	Phase 1\|Phase 2
NCT04001621	Fudan University	Metastatic Breast Cancer	June 26, 2019	Phase 2
NCT00625183	Roswell Park Cancer Institute\|National Cancer Institute (NCI)	Colorectal Cancer	March 2008	Phase 2
NCT04861987	Processa Pharmaceuticals	Advanced Cancer\|Refractory Cancer\|Tumor Gastric	June 18, 2021	Phase 1
NCT00960349	AstraZeneca	Gastric Cancer	August 2009	Phase 1
NCT00662025	Pfizer	Advanced+Metastatic Breast Cancer	April 2008	Phase 2
NCT00216073	Hoosier Cancer Research Network\|Sanofi\|Hoffmann-La Roche\|Walther Cancer Institute	Metastatic Breast Cancer	March 2004	Phase 2
NCT00226798	Rambam Health Care Campus\|Roche Pharma AG	Adenocarcinoma Clear Cell	December 2003	Phase 2
NCT00532948	Hoffmann-La Roche	Glioma	May 2007	Phase 1
NCT00601510	Technical University of Munich	Gastric Cancer	November 2007	Phase 1
NCT04937738	Ukrainian Society of Clinical Oncology	Gastric Cancer	July 21, 2021	Phase 2
NCT03950154	Tianjin Medical University Cancer Institute and Hospital	Colorectal Cancer	June 1, 2019	Phase 3
NCT00885755	Hoffmann-La Roche	Breast Cancer	August 13, 2009	Phase 2
NCT02555657	Merck Sharp & Dohme LLC	Metastatic Triple Negative Breast Cancer	October 13, 2015	Phase 3
NCT02465593	PharmaEngine	Rectal Cancer	June 2015	Phase 1\|Phase 2
NCT00459901	Peter Kozuch\|Hoffmann-La Roche\|Genentech, Inc.\|Beth Israel Medical Center	Metastatic Colorectal Cancer	June 2004	Phase 2
NCT05412082	University of Miami	Locally Advanced Rectal Cancer	October 5, 2022	Phase 1
NCT01433614	Thomas Hatschek\|Karolinska University Hospital	Metastatic Breast Cancer	December 2002	Phase 3
NCT00414271	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Stage T3-4NxM0 Gastric Cancer	January 2006	Phase 2
NCT03523312	Memorial Sloan Kettering Cancer Center	Pancreatic Cancer	April 30, 2018	Phase 2
NCT00796718	Hoffmann-La Roche	Colorectal Cancer	October 2008	Phase 2
NCT00618124	Pfizer	Solid Tumors\|Breast Cancer\|Neoplasms	May 2005	Phase 1
NCT05568095	Arcus Biosciences, Inc.\|Gilead Sciences	Advanced Upper Gastrointestinal Tract Adenocarcinoma	November 2022	Phase 3
NCT00398879	AEterna Zentaris	Colon Cancer	August 2005	Phase 2
NCT01134601	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Non-Metastatic Adenocarcinoma of the Rectum	May 24, 2010	Phase 1
NCT02560298	ECOG-ACRIN Cancer Research Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Anal Basaloid Carcinoma\|Anal Canal Cloacogenic Carcinoma\|Anal Squamous Cell Carcinoma\|Metastatic Anal Canal Carcinoma\|Recurrent Anal Canal Carcinoma\|Stage IIIB Anal Canal Cancer\|Stage IV Anal Canal Cancer	February 1, 2016	Phase 2
NCT00480597	Ludwig-Maximilians - University of Munich	Metastatic Breast Cancer	October 2002	Phase 2
NCT00212589	Odense University Hospital	Colorectal Cancer	December 2002	Phase 3
NCT05251948	Hoffmann-La Roche	Gastric and Gastroesophageal Junction Carcinoma	March 1, 2022	Phase 1\|Phase 2
NCT05625412	Bristol-Myers Squibb	Advanced Solid Tumors	November 29, 2022	Phase 1
NCT01355302	Eisai Inc.\|Quintiles, Inc.	Advanced or Metastatic Solid Tumors\|Previously Untreated Gastric Cancer	November 2011	Phase 1\|Phase 2
NCT00220168	Royal Marsden NHS Foundation Trust	Upper Gastrointestinal Tumours	January 2003	Phase 4
NCT00639522	Nanjing Sike Pharmaceutical Co., Ltd.	Gastric Carcinoma	May 2008	Phase 1
NCT04281576	NovoCure GmbH\|Zai Lab (Shanghai) Co., Ltd.\|NovoCure Ltd.	Gastric Cancer\|GastroEsophageal Cancer	December 19, 2019	Not Applicable
NCT01843829	Lisette Nixon\|Cancer Research UK\|Velindre NHS Trust	Oesophageal Cancer	October 2013	Phase 2
NCT00119314	University of Medicine and Dentistry of New Jersey\|National Cancer Institute (NCI)\|Rutgers, The State University of New Jersey	Carcinoma of Unknown Primary	July 2004	Phase 2
NCT00238147	University of Washington	Esophageal Cancer	September 2004	Phase 1
NCT00004012	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Fallopian Tube Cancer\|Ovarian Cancer\|Primary Peritoneal Cavity Cancer	December 1998	Phase 2
NCT00647530	University of Birmingham	Colorectal Cancer	May 15, 2008	Phase 2\|Phase 3
NCT03403049	Albert Einstein College of Medicine\|Shanghai Proton and Heavy Ion Center	Pancreatic Cancer\|Cancer	April 1, 2016	Phase 1
NCT01821612	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Acinar Cell Adenocarcinoma of the Pancreas\|Duct Cell Adenocarcinoma of the Pancreas\|Recurrent Pancreatic Cancer\|Stage II Pancreatic Cancer\|Stage III Pancreatic Cancer	May 2013	Early Phase 1
NCT02027363	Sun Yat-sen University	Colorectal Neoplasms\|Neoplasms Metastasis	January 2010	Phase 2
NCT00101075	Dana-Farber Cancer Institute\|National Cancer Institute (NCI)\|Sanofi-Synthelabo	Head and Neck Cancer	October 2004	Phase 2
NCT01196260	State Key Laboratory of Cancer Biology\|Tianjin Union Medical Center\|Beihua University\|Chengdu Medical College\|Shanghai Jiao Tong University School of Medicine	Colorectal Cancer	January 2004	Phase 2\|Phase 3
NCT00084942	Roswell Park Cancer Institute	Extrahepatic Bile Duct Cancer\|Gallbladder Cancer	October 2002	Phase 2
NCT00452673	Bristol-Myers Squibb	Advanced Breast Cancer	June 2007	Phase 1
NCT04134897	Blokhin´s Russian Cancer Research Center	Rectal Neoplasms Malignant\|Rectum Carcinoma\|Rectal Cancer	October 14, 2019	Phase 3
NCT00450203	Professor David Cunningham\|Cancer Research UK\|Roche Pharma AG\|GlaxoSmithKline\|Medical Research Council	Oesophagogastric Cancer	October 2007	Phase 2\|Phase 3
NCT00842244	Pfizer	Stomach Neoplasms\|Advanced Gastric Cancer	April 2009	Phase 1
NCT00536809	GlaxoSmithKline	Neoplasms, Colorectal	September 26, 2007	Phase 1
NCT00130936	AHS Cancer Control Alberta	Gastric Cancer\|Esophageal Cancer\|Tumors	October 2005	Phase 1\|Phase 2
NCT04701281	AllVascular	Liver Metastasis Colon Cancer	June 20, 2019	Phase 1\|Phase 2
NCT00354601	Wake Forest University Health Sciences\|National Cancer Institute (NCI)	Fallopian Tube Cancer\|Ovarian Cancer\|Peritoneal Cavity Cancer	January 2006	Phase 2
NCT00296062	Case Comprehensive Cancer Center\|National Cancer Institute (NCI)	Colorectal Cancer\|Unspecified Adult Solid Tumor, Protocol Specific	March 2006	Phase 1
NCT05382442	Akeso	Metastatic Colorectal Cancer	July 27, 2022	Phase 2
NCT01112826	Sun Yat-sen University	Breast Cancer	April 23, 2010	Phase 3
NCT04745975	Fudan University	Triple Negative Breast Cancer	February 1, 2021	Phase 2
NCT03465202	Newcastle-upon-Tyne Hospitals NHS Trust\|University of Newcastle Upon-Tyne	Breast Cancer\|Colorectal Cancer	May 2016	Phase 4
NCT00363584	University Hospital Southampton NHS Foundation Trust\|National Cancer Institute (NCI)	Extrahepatic Bile Duct Cancer\|Gallbladder Cancer\|Liver Cancer	March 2006	Phase 3
NCT02380131	Hebei Medical University	HER-2 Positive Gastric Cancer\|Liver Metastasis	February 2013	Phase 4
NCT00686166	Southwest Oncology Group\|National Cancer Institute (NCI)	Colorectal Cancer	February 2009	Phase 2
NCT04400695	RemeGen Co., Ltd.	Breast Cancer	September 29, 2020	Phase 3
NCT00280761	UNC Lineberger Comprehensive Cancer Center\|National Cancer Institute (NCI)	Colorectal Cancer	December 2003
NCT00194727	University of Washington\|Hoffmann-La Roche\|Pfizer	Breast Neoplasm	May 2002	Phase 2
NCT00049335	Southwest Oncology Group\|National Cancer Institute (NCI)	Colorectal Cancer	February 2003	Phase 2
NCT03299660	Peter MacCallum Cancer Centre, Australia	Rectal Cancer	April 30, 2018	Phase 2
NCT00227656	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Breast Cancer\|Metastatic Cancer	September 2005	Phase 2
NCT00798252	Bristol-Myers Squibb	Advanced Cancer	March 2009	Phase 1
NCT01032850	New Mexico Cancer Care Alliance\|Bayer	Hepatocellular Carcinoma	September 2009	Phase 2
NCT02359058	Eli Lilly and Company	Stomach Neoplasms	February 2015	Phase 1
NCT03257163	Rutgers, The State University of New Jersey\|National Cancer Institute (NCI)	Epstein-Barr Virus Positive\|Gastric Adenocarcinoma\|Mismatch Repair Protein Deficiency\|Stage IB Gastric Cancer AJCC v7\|Stage II Gastric Cancer AJCC v7\|Stage IIA Gastric Cancer AJCC v7\|Stage IIB Gastric Cancer AJCC v7\|Stage III Gastric Cancer AJCC v7\|Stage IIIA Gastric Cancer AJCC v7\|Stage IIIB Gastric Cancer AJCC v7\|Stage IIIC Gastric Cancer AJCC v7	September 29, 2017	Phase 2
NCT04083365	AUSL Romagna Rimini\|AstraZeneca\|Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori	RECTAL CANCER	January 1, 2020	Phase 2
NCT00411762	Yale University\|PhytoCeutica\|National Comprehensive Cancer Network\|Roche Pharma AG	Pancreatic Cancer	December 2006	Phase 1\|Phase 2
NCT00828672	Universitaire Ziekenhuizen KU Leuven	Locally Advanced Rectal Cancer	June 2009	Phase 2
NCT03351296	Gustave Roussy, Cancer Campus, Grand Paris\|National Cancer Institute, France	Pancreatic Cancer	February 9, 2018	Phase 2
NCT00069108	Hoffmann-La Roche	Colorectal Cancer	July 2003	Phase 3
NCT04351867	LiNing\|Henan Cancer Hospital	Stomach Neoplasms	September 2020	Phase 3
NCT02893540	Ruijin Hospital	Colorectal Cancer	September 2016	Phase 2\|Phase 3
NCT03387085	ImmunityBio, Inc.	Triple Negative Breast Cancer	March 16, 2018	Phase 1\|Phase 2
NCT00209092	Emory University\|Georgia Center for Oncology Research & Education\|Sanofi	Breast Cancer	August 2006	Phase 2
NCT00807859	Amgen	Breast Cancer\|Breast Neoplasms\|Breast Tumors\|Cancer\|Locally Recurrent and Metastatic Breast Cancer\|Metastases\|Metastatic Cancer\|Oncology\|Solid Tumors\|Tumors	March 9, 2009	Phase 1
NCT02973386	Sun Yat-sen University	Local Advanced High Risk Nasopharyngeal Carcinoma	January 2017	Phase 3
NCT00440167	PD Dr. med. Volker Heinemann\|Roche Pharma AG\|Ludwig-Maximilians - University of Munich	Pancreatic Cancer	June 2006	Phase 3
NCT03136406	ImmunityBio, Inc.	Pancreatic Cancer	August 14, 2017	Phase 1\|Phase 2
NCT05238831	OHSU Knight Cancer Institute\|Oregon Health and Science University\|Genentech, Inc.	Anatomic Stage III Breast Cancer AJCC v8\|Anatomic Stage IV Breast Cancer AJCC v8\|Locally Advanced Breast Carcinoma\|Locally Advanced Malignant Solid Neoplasm\|Locally Advanced Ovarian Carcinoma\|Metastatic Breast Carcinoma\|Metastatic Malignant Solid Neoplasm\|Metastatic Ovarian Carcinoma\|Refractory Breast Carcinoma\|Refractory Malignant Solid Neoplasm\|Refractory Ovarian Carcinoma\|Stage III Ovarian Cancer AJCC v8\|Stage IV Ovarian Cancer AJCC v8\|Unresectable Malignant Solid Neoplasm\|Unresectable Ovarian Carcinoma	December 1, 2022	Phase 2
NCT00095901	Dana-Farber Cancer Institute\|National Cancer Institute (NCI)\|Roche Pharma AG	Head and Neck Cancer	June 2004	Phase 2
NCT04430738	Seagen Inc.	Colorectal Carcinoma\|Gastric Adenocarcinoma\|GEJ Adenocarcinoma\|Esophageal Adenocarcinoma\|Cholangiocarcinoma\|Gallbladder Carcinoma	September 15, 2020	Phase 1\|Phase 2
NCT00118105	Southwest Oncology Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Colorectal Cancer\|Metastatic Cancer	November 2006	Phase 2
NCT02648425	Aslan Pharmaceuticals	Solid Tumor	August 5, 2014	Phase 1
NCT04202978	Zhongshan Hospital Xiamen University	Hepatic Metastasis of Colorectal Cancer	March 1, 2020	Phase 1\|Phase 2
NCT04401709	Samsung Medical Center	Biliary Tract Cancer	April 1, 2021	Phase 3
NCT01041404	Hoffmann-La Roche\|Chugai Pharmaceutical	Gastric Cancer	September 2005	Phase 3
NCT04333706	University of Florida\|National Cancer Institute (NCI)	Breast\|Metastatic\|Triple Negative\|Cancer\|Disseminated Tumor Cell	September 26, 2020	Phase 1\|Phase 2
NCT04095390	Jinming Yu\|Jiangsu HengRui Medicine Co., Ltd.\|Shandong Cancer Hospital and Institute	Metastatic Breast Cancer\|HER2-positive Breast Cancer	September 30, 2019	Phase 2
NCT01921751	Radiation Therapy Oncology Group\|National Cancer Institute (NCI)\|NRG Oncology	Pancreatic Adenocarcinoma\|Stage III Pancreatic Cancer	August 2013	Phase 2
NCT00082433	R-Pharm	Cancer\|Breast Cancer	November 2003	Phase 3
NCT01302613	University of Texas Southwestern Medical Center	Stage II Rectal Cancer\|Stage III Rectal Cancer	March 2011	Phase 1\|Phase 2
NCT03125980	Fudan University	Locally Advanced Colon Cancer	May 2017	Phase 3
NCT00024102	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)\|NCIC Clinical Trials Group	Breast Cancer	September 2001	Phase 3
NCT00263705	Jules Bordet Institute	Elderly Patients\|Breast Cancer	January 2003	Phase 2
NCT03381352	Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Anal Cancer	December 2, 2015	Phase 2
NCT04296162	Fudan University	Breast Cancer	March 1, 2019	Phase 2
NCT04607421	Pfizer\|Ono Pharmaceutical Co. Ltd\|Merck KGaA, Darmstadt, Germany	Neoplasms	December 21, 2020	Phase 3
NCT02704520	Royal Marsden NHS Foundation Trust	Rectal Cancer	March 2016	Phase 2\|Phase 3
NCT00869570	Swiss Group for Clinical Cancer Research	Colorectal Cancer	March 2009	Phase 1\|Phase 2
NCT05262335	Ruijin Hospital\|Chia Tai Tianqing Pharmaceutical Group Co., Ltd.	Gastrointestinal Tumors	December 1, 2021	Phase 2
NCT02025192	Seagen Inc.	HER2 Positive Metastatic Breast Cancers	December 31, 2013	Phase 1
NCT02024009	University of Oxford\|Celgene\|Cancer Research UK	Pancreatic Neoplasms (Locally Advanced Non-metastatic)	March 2016	Phase 1\|Phase 2
NCT03424005	Hoffmann-La Roche\|Seagen Inc.\|Gilead Sciences	Triple Negative Breast Cancer	April 2, 2018	Phase 1\|Phase 2
NCT05451719	Fudan University	Colorectal Cancer\|Colorectal Cancer Stage IV	July 2022	Phase 2
NCT00005908	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Breast Cancer\|Breast Neoplasm	June 2000	Phase 2
NCT00212615	Odense University Hospital	C04.588.274.476.411.307	February 2004	Phase 2\|Phase 3
NCT04263298	Herui Yao\|Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Metastatic Breast Cancer	May 1, 2018	Phase 3
NCT00983268	Vanderbilt-Ingram Cancer Center\|National Cancer Institute (NCI)\|National Comprehensive Cancer Network	Pancreatic Cancer\|Periampullary Adenocarcinoma	October 2009	Phase 1
NCT05042791	Jiangxi Provincial Cancer Hospital	HER2-positive Metastatic Breast Cancer	March 1, 2022	Phase 2
NCT03501979	University of Alabama at Birmingham\|Translational Breast Cancer Research Consortium\|Johns Hopkins University\|Seagen Inc.\|University of Michigan\|Georgetown University\|University of California, San Francisco\|University of Chicago\|Indiana University\|University of Washington\|University of Texas	Metastatic Breast Cancer\|Leptomeningeal Disease	February 20, 2019	Phase 2
NCT04363801	Leap Therapeutics, Inc.\|BeiGene	Gastric Cancer\|Gastric Adenocarcinoma\|GastroEsophageal Cancer	July 29, 2020	Phase 2
NCT00083525	Heidelberg Pharma AG\|United States Department of Defense	Advanced Malignancies	May 2004	Phase 1
NCT03923166	Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Breast Cancer	April 19, 2019	Phase 2
NCT03111732	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Biliary Tract Neoplasms\|Cholangiocarcinoma\|Bile Duct Cancer\|Liver Cancer\|Gallbladder Cancer	June 14, 2017	Phase 2
NCT01249638	Ludwig-Maximilians - University of Munich\|Roche Pharma AG	Colorectal Cancer Metastatic	December 2010	Phase 3
NCT02244489	Sierra Oncology, Inc.	Relapsed+Refractory Metastatic Pancreatic Ductal Adenocarcinoma	November 5, 2014	Phase 1
NCT01552967	Sixth Affiliated Hospital, Sun Yat-sen University	Colorectal Adenocarcinoma	March 2012	Phase 2
NCT01705002	Lipomedix Pharmaceuticals Inc.	Cancer\|Solid Tumor\|Metastatic Colorectal Cancer (mCRC)	October 2012	Phase 1
NCT00148876	German Breast Group\|Hoffmann-La Roche	Breast Cancer	September 2003	Phase 3
NCT00437073	GlaxoSmithKline	Neoplasms, Breast	May 2007	Phase 2
NCT03006705	Ono Pharmaceutical Co. Ltd\|Bristol-Myers Squibb	Gastric Cancer	January 31, 2017	Phase 3
NCT01145404	National Center for Tumor Diseases, Heidelberg	GastroEsophageal Cancer	June 2010	Phase 2
NCT00242788	AstraZeneca	Colorectal Cancer	February 2004	Phase 1\|Phase 2
NCT00095641	Southwest Oncology Group\|National Cancer Institute (NCI)	Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity\|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity\|Recurrent Squamous Cell Carcinoma of the Hypopharynx\|Recurrent Squamous Cell Carcinoma of the Larynx\|Recurrent Squamous Cell Carcinoma of the Oropharynx		Phase 2
NCT03518242	Fred Hutchinson Cancer Center\|GlaxoSmithKline	Breast Cancer Female\|Anatomic Stage IIB Breast Cancer AJCC v8\|Anatomic Stage III Breast Cancer AJCC v8\|Anatomic Stage IIIA Breast Cancer AJCC v8\|Anatomic Stage IIIB Breast Cancer AJCC v8\|Anatomic Stage IIIC Breast Cancer AJCC v8\|Invasive Breast Carcinoma\|Prognostic Stage IIB Breast Cancer AJCC v8\|Prognostic Stage III Breast Cancer AJCC v8\|Prognostic Stage IIIA Breast Cancer AJCC v8\|Prognostic Stage IIIB Breast Cancer AJCC v8\|Prognostic Stage IIIC Breast Cancer AJCC v8	June 6, 2018	Phase 1
NCT03901339	Gilead Sciences	Metastatic Breast Cancer	May 8, 2019	Phase 3
NCT05360277	Yanhong Deng\|Sun Yat-sen University	Metastatic Colorectal Cancer	December 1, 2022	Phase 2
NCT00107250	NCIC Clinical Trials Group\|Canadian Cancer Trials Group	Colorectal Cancer\|Lung Cancer\|Unspecified Adult Solid Tumor, Protocol Specific	January 13, 2005	Phase 1
NCT01873833	University of Southern California\|National Cancer Institute (NCI)	HER2-positive Breast Cancer\|Recurrent Breast Cancer\|Stage IV Breast Cancer	July 29, 2013	Phase 2
NCT00642603	Hoffmann-La Roche	Colorectal Cancer	May 2008	Phase 2
NCT01696695	Hoffmann-La Roche	Colorectal Cancer	July 2011
NCT00193128	SCRI Development Innovations, LLC\|Sanofi-Synthelabo\|Aventis Pharmaceuticals	Esophagus Cancer	April 2004	Phase 1\|Phase 2
NCT00274768	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|National Cancer Institute (NCI)	Breast Cancer	April 2004	Phase 2
NCT02368860	National Cancer Centre, Singapore\|National Medical Research Council (NMRC), Singapore	Pancreatic Cancer	September 17, 2013	Phase 1
NCT00717990	University Hospital of Crete	Metastatic Colorectal Cancer	April 2008	Phase 2
NCT02494596	Hoffmann-La Roche	Solid Tumor	January 2004	Phase 1
NCT04929028	National Cancer Institute (NCI)	AIDS-Related Anal Carcinoma\|Anal Basaloid Carcinoma\|Anal Canal Cloacogenic Carcinoma\|Anal Margin Squamous Cell Carcinoma\|Anal Squamous Cell Carcinoma\|HIV Infection\|Rectal Squamous Cell Carcinoma\|Stage I Anal Cancer AJCC v8\|Stage II Anal Cancer AJCC v8\|Stage II Rectal Cancer AJCC v8\|Stage IIA Anal Cancer AJCC v8\|Stage IIA Rectal Cancer AJCC v8\|Stage IIB Anal Cancer AJCC v8\|Stage IIB Rectal Cancer AJCC v8\|Stage IIC Rectal Cancer AJCC v8\|Stage III Anal Cancer AJCC v8\|Stage III Rectal Cancer AJCC v8\|Stage IIIA Anal Cancer AJCC v8\|Stage IIIA Rectal Cancer AJCC v8\|Stage IIIB Anal Cancer AJCC v8\|Stage IIIB Rectal Cancer AJCC v8\|Stage IIIC Anal Cancer AJCC v8\|Stage IIIC Rectal Cancer AJCC v8	November 23, 2021	Phase 2
NCT00121836	Hoffmann-La Roche	Breast Cancer	June 2005	Phase 4
NCT00201825	Tony Bekaii-Saab\|Roche Pharma AG\|Ohio State University Comprehensive Cancer Center	Lung Cancer\|Non-Small-Cell Lung Carcinoma	December 2004	Phase 2
NCT00468585	Memorial Sloan Kettering Cancer Center	Breast Cancer	June 2005	Phase 1\|Phase 2
NCT02000882	US Oncology Research\|Novartis Pharmaceuticals	Brain Metastases\|Breast Cancer\|Metastatic Breast Cancer	May 29, 2014	Phase 2
NCT02083653	Symphogen A+S	Metastatic Colorectal Cancer	March 6, 2014	Phase 2
NCT03858972	Odonate Therapeutics, Inc.	Breast Cancer	February 5, 2019	Phase 2
NCT00346099	NSABP Foundation Inc\|Amgen	Rectal Cancer\|Neoplasm Metastasis	June 2006	Phase 2
NCT02795988	Imugene Limited	Gastrointestinal Neoplasms\|Adenocarcinoma	August 30, 2017	Phase 1\|Phase 2
NCT01315431	Genta Incorporated	Solid Tumor	March 2011	Phase 1
NCT02897050	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Breast Cancer	September 2016	Phase 2
NCT03734029	Daiichi Sankyo, Inc.\|Daiichi Sankyo Co., Ltd.\|AstraZeneca	Breast Cancer	December 27, 2018	Phase 3
NCT00745134	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Rectal Mucinous Adenocarcinoma\|Rectal Signet Ring Cell Adenocarcinoma\|Recurrent Rectal Carcinoma\|Stage IIA Rectal Cancer AJCC v7\|Stage IIB Rectal Cancer AJCC v7\|Stage IIC Rectal Cancer AJCC v7\|Stage IIIA Rectal Cancer AJCC v7\|Stage IIIB Rectal Cancer AJCC v7\|Stage IIIC Rectal Cancer AJCC v7	August 11, 2008	Phase 2
NCT00026442	Pharmatech Oncology\|National Cancer Institute (NCI)	Breast Cancer	November 2001	Phase 2
NCT02085005	Sanofi\|Regeneron Pharmaceuticals	Colorectal Cancer Metastatic	March 2014	Phase 2
NCT02726399	Memorial Sloan Kettering Cancer Center	Gastric Cancer\|Gastroesophageal Junction Cancer	March 18, 2016	Phase 2
NCT04721977	Merck Sharp & Dohme LLC	Breast Cancer	April 8, 2021	Phase 2
NCT01118377	Hoffmann-La Roche\|Pediatric Brain Tumor Consortium	Brainstem Glioma	May 2007	Phase 2
NCT01399190	Hoffmann-La Roche	Colorectal Cancer	July 2011
NCT02608073	Hoffmann-La Roche	Nasopharyngeal Cancer	November 2004	Phase 2
NCT01918852	Dutch Colorectal Cancer Group\|Nordic Pharma SAS	Colorectal Cancer\|Metastases	December 2013	Phase 3
NCT01474187	Fudan University	Rectal Cancer	November 2011	Phase 1
NCT02355379	Federation Francophone de Cancerologie Digestive	Colonic Adenocarcinoma	January 2015	Phase 3
NCT04534218	Centre Hospitalier Universitaire de Besancon\|Bayer	Colo-rectal Cancer\|Metastatic Cancer	October 16, 2020	Phase 2
NCT04295317	Shanghai Zhongshan Hospital	Intrahepatic Cholangiocarcinoma	August 1, 2020	Phase 2
NCT01754623	H. Lee Moffitt Cancer Center and Research Institute	Pancreatic Cancer	February 2013	Phase 2
NCT00151047	University of Michigan Rogel Cancer Center	Prostate Cancer	March 2003	Phase 2
NCT00260364	Royal Marsden NHS Foundation Trust\|Professor Cunningham´s Clinical Research Fund\|Hoffmann-La Roche	Pancreatic Cancer	November 2005	Phase 1\|Phase 2
NCT02419495	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Advanced Malignant Solid Neoplasm\|Clinical Stage III Cutaneous Melanoma AJCC v8\|Clinical Stage IV Cutaneous Melanoma AJCC v8\|Fallopian Tube Carcinoma\|Metastatic Lung Non-Small Cell Carcinoma\|Metastatic Malignant Solid Neoplasm\|Metastatic Melanoma\|Metastatic Renal Cell Carcinoma\|Ovarian Carcinoma\|Pathologic Stage III Cutaneous Melanoma AJCC v8\|Pathologic Stage IIIA Cutaneous Melanoma AJCC v8\|Pathologic Stage IIIB Cutaneous Melanoma AJCC v8\|Pathologic Stage IIIC Cutaneous Melanoma AJCC v8\|Pathologic Stage IIID Cutaneous Melanoma AJCC v8\|Pathologic Stage IV Cutaneous Melanoma AJCC v8\|Primary Peritoneal Carcinoma\|Stage III Lung Cancer AJCC v8\|Stage III Renal Cell Cancer AJCC v8\|Stage IIIA Lung Cancer AJCC v8\|Stage IIIB Lung Cancer AJCC v8\|Stage IIIC Lung Cancer AJCC v8\|Stage IV Lung Cancer AJCC v8\|Stage IV Renal Cell Cancer AJCC v8\|Stage IVA Lung Cancer AJCC v8\|Stage IVB Lung Cancer AJCC v8\|Triple-Negative Breast Carcinoma\|Unresectable Lung Non-Small Cell Carcinoma\|Unresectable Melanoma\|Unresectable Renal Cell Carcinoma	June 26, 2015	Phase 1
NCT00640081	Cheryl Pugh\|Medical Research Council	Colorectal Cancer	July 2007	Phase 2
NCT05228431	Zhen-Hai Lu\|Sun Yat-sen University	Advanced Rectal Cancer	December 1, 2022	Phase 2
NCT01843452	Centre Hospitalier Universitaire Vaudois	Carcinoma of Anal Canal	December 2012	Phase 2
NCT00050167	M.D. Anderson Cancer Center\|Roche Pharma AG	Breast Cancer	November 2002	Phase 1
NCT01369433	AVEO Pharmaceuticals, Inc.	Solid Tumors	June 2010	Not Applicable
NCT03197584	ImmunityBio, Inc.	Ovarian Cancer	December 2017	Phase 1\|Phase 2
NCT01152710	Institute of Oncology Ljubljana	Resectable Rectal Cancer Clinical Stage II and III	June 2004	Phase 2
NCT02205047	European Organisation for Research and Treatment of Cancer - EORTC	Malignant Neoplasm of Stomach\|Malignant Neoplasm of Cardio-esophageal Junction of Stomach\|Epidermal Growth Factor Receptor (EGFR) Protein Overexpression	July 15, 2015	Phase 2
NCT01026142	Hoffmann-La Roche	Breast Cancer	January 26, 2010	Phase 3
NCT00570908	Baylor Breast Care Center	Breast Cancer	February 2009	Phase 2
NCT00153907	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital	Breast Cancer	March 2002	Phase 1
NCT02483247	Sumitomo Pharma Oncology, Inc.	Cancer	September 2015	Phase 1
NCT00297141	Austrian Breast & Colorectal Cancer Study Group\|Sanofi-Synthelabo\|Hoffmann-La Roche	Rectal Cancer	October 2004	Phase 2
NCT00003902	Swiss Group for Clinical Cancer Research	Breast Cancer	March 1999	Phase 1\|Phase 2
NCT00544011	Hopital Jean Minjoz\|National Cancer Institute (NCI)	Colorectal Cancer	April 2007	Phase 2
NCT01442155	Hoffmann-La Roche	Colorectal Cancer	October 2011
NCT00717951	Academy Military Medical Science, China\|Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Advanced Breast Cancer	May 2008	Phase 2
NCT01159171	Hoffmann-La Roche	Colorectal Cancer	January 2006	Phase 2
NCT04866108	Beijing Friendship Hospital	Unresectable Metastatic Colorectal Cancer	December 8, 2021	Phase 2
NCT04464174	MedSIR\|Hoffmann-La Roche	Triple Negative Breast Cancer	October 8, 2020	Phase 2
NCT01468389	The Affiliated Hospital of the Chinese Academy of Military Medical Sciences	Gastric Cancer	November 2011	Phase 3
NCT01534546	Peking University\|Taiho Pharmaceutical Co., Ltd.	Advanced Gastric Carcinoma	March 2012	Phase 3
NCT01898104	National Cancer Institute, Naples	Colorectal Cancer	May 2012	Phase 1\|Phase 2
NCT00719550	Amgen	Esophagogastric Junction Adenocarcinoma\|Gastric Cancer\|Esophageal Cancer	February 2009	Phase 1\|Phase 2
NCT00320749	Tony Bekaii-Saab\|University of Michigan Rogel Cancer Center\|Ohio State University Comprehensive Cancer Center	Pancreatic Cancer	December 2005	Phase 1
NCT01463982	Hanmi Pharmaceutical Company Limited	Solid Tumor\|Advanced Cancer	December 2010	Phase 1
NCT04089631	Technische Universität Dresden	Colon Cancer Stage II	June 26, 2020	Phase 3
NCT00961571	Georgetown University\|Pfizer	Metastatic Colorectal Cancer	August 2009	Phase 2
NCT01777945	Hoffmann-La Roche	Breast Cancer	December 2012
NCT00689702	Institute of Oncology Ljubljana	Rectal Cancer	February 2007	Phase 2
NCT01360593	David A. Clump, MD, PhD\|University of Pittsburgh	Pancreatic Cancer	July 25, 2011	Phase 2
NCT05307198	Second Affiliated Hospital, School of Medicine, Zhejiang University	Rectal Neoplasms	April 25, 2022	Phase 2
NCT00075556	GERCOR - Multidisciplinary Oncology Cooperative Group\|National Cancer Institute (NCI)	Colorectal Cancer	January 2002	Phase 2
NCT03280407	Zealand University Hospital	Colorectal Neoplasm\|Colorectal Cancer\|Rectal Neoplasms\|Chemotherapy Effect\|Intestinal Disease\|Intestinal Neoplasms\|Rectal Cancer	March 1, 2017	Phase 2
NCT00635323	Pfizer	Carcinoma, Hepatocellular	November 2002	Phase 2
NCT00660426	Washington University School of Medicine	Advanced Gastrointestinal Malignancies\|Solid Tumors	March 2005	Phase 1
NCT04198727	Centre Antoine Lacassagne\|Cerbaliance	Breast Neoplasm Malignant Female	July 20, 2020	Not Applicable
NCT00707278	University of Utah	Cancer\|Pancreas	September 2005	Phase 1
NCT03161522	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Gastric Adenocarcinoma\|Oligometastasis\|Stage IV Esophageal Adenocarcinoma AJCC v7\|Stage IV Esophageal Cancer AJCC v7\|Stage IV Gastric Cancer AJCC v7	February 19, 2018	Phase 2
NCT02288195	Sun Yat-sen University\|Shantou Central Hospital\|Liaoning Tumor Hospital & Institute\|The First Affiliated Hospital with Nanjing Medical University\|Fujian Cancer Hospital\|Guangdong Provincial Hospital of Traditional Chinese Medicine\|First Affiliated Hospital of Chongqing Medical University\|The First Affiliated Hospital of Guangzhou Medical University\|Guangdong Provincial People´s Hospital\|Cancer Hospital of Guangxi Medical University\|Meizhou People´s Hospital\|Henan Cancer Hospital\|Affiliated Cancer Hospital of Shantou University Medical College\|Hubei Cancer Hospital\|The First Affiliated Hospital of Kunming Medical College\|Longyan City First Hospital\|Shengjing Hospital\|Zhejiang Cancer Hospital\|Jiangmen Central Hospital\|West China Hospital\|The Third Affiliated Hospital of Kunming Medical College.	Rectal Neoplasms	August 13, 2014	Phase 3
NCT00176787	University of Michigan Rogel Cancer Center\|Hoffmann-La Roche	Rectal Cancer	October 2000	Phase 2
NCT00524069	Roswell Park Cancer Institute\|National Cancer Institute (NCI)	Pancreatic Cancer	January 2007	Not Applicable
NCT00658840	National Cancer Center, Korea	Pancreatic Cancer	June 2006	Phase 2
NCT00634751	University of Wisconsin, Madison\|Bayer\|Sanofi	Pancreatic Neoplasms\|Bile Duct Neoplasms	February 2008	Phase 1\|Phase 2
NCT00543842	M.D. Anderson Cancer Center\|Genentech, Inc.	Rectal Cancer	December 2007	Phase 1
NCT05288777	University of Virginia	Breast Cancer\|Breast Cancer Stage I\|Breast Cancer Stage II\|Breast Cancer Stage III	May 2022	Phase 2\|Phase 3
NCT00493636	Accelerated Community Oncology Research Network\|Amgen	Breast Cancer	June 2007	Phase 2
NCT01295086	Odense University Hospital\|Aalborg University Hospital\|Aarhus University Hospital\|Rigshospitalet, Denmark	Adenocarcinoma	March 2011	Not Applicable
NCT00447330	Duke University\|Hoffmann-La Roche\|Sanofi\|Genentech, Inc.	Esophageal Neoplasms\|Stomach Neoplasms\|Neoplasm Metastasis	February 2007	Phase 2
NCT03563144	ImmunityBio, Inc.	Metastatic Pancreatic Cancer	August 2018	Phase 2
NCT02335411	Merck Sharp & Dohme LLC	Gastric Adenocarcinoma\|Gastroesophageal Junction Adenocarcinoma	February 3, 2015	Phase 2
NCT05249101	CG Pharmaceuticals, Inc	Metastatic Pancreatic Adenocarcinoma	July 1, 2022	Phase 1\|Phase 2
NCT02565641	Hoffmann-La Roche	Pancreatic Cancer	March 2003	Phase 2
NCT04940546	Sun Yat-sen University	Colorectal Cancer Metastatic	June 16, 2021	Phase 1\|Phase 2
NCT00486356	University of Nebraska\|National Cancer Institute (NCI)	Extrahepatic Bile Duct Cancer\|Gallbladder Cancer\|Gastric Cancer\|Liver Cancer\|Unspecified Adult Solid Tumor, Protocol Specific	October 2004	Phase 1
NCT02491697	The First People´s Hospital of Changzhou	Breast Cancer	February 2016	Phase 2
NCT01290718	Hoffmann-La Roche	Breast Cancer	December 2011	Phase 2
NCT04340401	Peking University Cancer Hospital & Institute	Rectal Cancer	May 25, 2020	Phase 2
NCT00070213	Medical Research Council\|University of Leeds	Colorectal Cancer	September 2003	Phase 3
NCT00634088	R-Pharm\|GlaxoSmithKline	Locally Advanced or Metastatic Breast Cancer	June 2008	Phase 1
NCT01774786	Hoffmann-La Roche	Gastric Cancer	June 10, 2013	Phase 3
NCT05062317	M.D. Anderson Cancer Center	Liver Metastases	April 26, 2022	Phase 2
NCT04564898	Gruppo Oncologico del Nord-Ovest	Colorectal Cancer Metastatic	January 25, 2022	Phase 1\|Phase 2
NCT01718873	National Cancer Institute, Naples	Colorectal Cancer	May 2012	Phase 3
NCT05342792	Sun Yat-sen University\|Tongji Hospital\|Wuhan Union Hospital, China\|Xiangya Hospital of Central South University\|Affiliated Cancer Hospital of Guizhou Medical University\|Cancer Hospital of Guangxi Medical University\|First People´s Hospital of Foshan\|Chongqing University Cancer Hospital\|Hubei Cancer Hospital\|Hunan Cancer Hospital\|The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School\|Fifth Affiliated Hospital, Sun Yat-Sen University\|Shandong Provincial Hospital	Nasopharyngeal Carcinoma	April 17, 2022	Phase 3
NCT00446290	Asan Medical Center	Stomach Cancer	March 2006	Phase 1
NCT04395989	Fudan University	TNBC - Triple-Negative Breast Cancer	May 15, 2020	Phase 2
NCT03684863	Shandong Cancer Hospital and Institute	HER2-positive Breast Cancer	October 2018	Phase 2
NCT00684216	The Netherlands Cancer Institute	Breast Cancer	April 2008	Phase 2\|Phase 3
NCT00235235	Hoosier Cancer Research Network\|United States Department of Defense\|Indiana University School of Medicine\|Walther Cancer Institute	Breast Cancer	September 2005
NCT01498458	German Breast Group	Metastatic Breast Cancer	October 2010	Phase 1
NCT00270491	ARCAGY+ GINECO GROUP	Breast Cancer\|Neoplasm Metastasis	December 2005	Phase 2
NCT00483366	University of Nebraska\|National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	August 2006	Phase 1
NCT00435409	Pfizer	Breast Neoplasms	February 2007	Phase 3
NCT00037609	M.D. Anderson Cancer Center\|Cell Pathways	Breast Neoplasms\|Metastases, Neoplasm	January 2001	Phase 1\|Phase 2
NCT01591733	Massachusetts General Hospital\|National Cancer Institute (NCI)	Pancreatic Cancer	May 2012	Phase 2
NCT00787787	University of Washington\|National Cancer Institute (NCI)	Adult Primary Hepatocellular Carcinoma\|Advanced Adult Primary Liver Cancer\|Localized Unresectable Adult Primary Liver Cancer\|Recurrent Adult Primary Liver Cancer	September 2008	Phase 2
NCT02008656	Memorial Sloan Kettering Cancer Center\|Colon and Rectal Surgery Inc.\|The Cleveland Clinic\|John Muir Health\|Oregon Health and Science University\|St. Joseph Hospital of Orange\|University of California, Irvine\|University of California, San Francisco\|University of Chicago\|University of South Florida\|University of Vermont\|University of Washington\|Medstar Health Research Institute\|Washington University School of Medicine\|Creighton University Medical Center\|The Methodist Hospital Research Institute\|University of Rochester\|University of Virginia\|St. Paul´s Hospital\|St. Joseph, Florida\|Cleveland Clinic Florida\|University of Colorado, Denver\|University of Michigan	Rectal Cancer	November 2013	Phase 2
NCT00732810	Merck Sharp & Dohme LLC	Breast Neoplasms\|Carcinoma, Non-Small-Cell Lung	July 2008	Phase 2
NCT02216149	Heikki Joensuu\|Helsinki University Central Hospital	Esophagus Cancer\|Stomach Cancer\|Small Bowel Cancer\|Colon Cancer\|Rectum Cancer	January 2015	Phase 2
NCT04787354	Hallym University Medical Center	Gastric Cancer	November 1, 2021	Phase 3
NCT00016926	Gynecologic Oncology Group\|National Cancer Institute (NCI)\|GOG Foundation	Cervical Cancer	April 2001	Phase 2
NCT00062426	Prologue Research International\|National Cancer Institute (NCI)	Colorectal Cancer	May 2003	Phase 3
NCT04366713	Puma Biotechnology, Inc.	HER2 Amplified Breast Cancer	June 30, 2020	Phase 2
NCT05507658	Xijing Hospital	Locally Advanced Gastric Adenocarcinoma	July 18, 2022	Phase 2
NCT01245582	Sanofi	Hepatic Neoplasm Malignant	July 2011	Phase 3
NCT00321685	National Cancer Institute (NCI)	Rectal Adenocarcinoma\|Stage II Rectal Cancer AJCC v7\|Stage III Rectal Cancer AJCC v7	July 25, 2006	Phase 2
NCT02595424	ECOG-ACRIN Cancer Research Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Gastric Neuroendocrine Carcinoma\|Intestinal Neuroendocrine Carcinoma\|Pancreatic Neuroendocrine Carcinoma	November 6, 2015	Phase 2
NCT00477711	Peking University\|Merck Sharp & Dohme LLC	Gastric Cancer	March 2007	Phase 2
NCT00423696	UNICANCER	Colorectal Cancer	March 23, 2006	Phase 2
NCT00733616	Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)\|Sanofi\|Hoffmann-La Roche	Gastric Cancer	November 2008	Phase 2
NCT05484375	Affiliated Cancer Hospital & Institute of Guangzhou Medical University\|Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University\|Hunan Cancer Hospital	Metastatic Nasopharyngeal Carcinoma	September 2022	Phase 2
NCT02199236	Memorial Sloan Kettering Cancer Center	Rectal or Anal Cancer	July 2014	Phase 1
NCT01534637	Wake Forest University Health Sciences\|National Cancer Institute (NCI)\|Merck Sharp & Dohme LLC	Extrahepatic Bile Duct Cancer\|Nausea\|Vomiting\|Stage II Pancreatic Cancer\|Stage III Pancreatic Cancer\|Stage IV Pancreatic Cancer	August 2006	Phase 2
NCT00337103	Eisai Inc.	Metastatic Breast Cancer	September 20, 2006	Phase 3
NCT01064999	Fudan University\|Zhejiang Cancer Hospital\|First People Hospital of Zhejiang\|RenJi Hospital	Rectal Cancer	March 2010	Phase 2\|Phase 3
NCT04922008	Fudan University	Breast Cancer	July 1, 2021	Phase 2
NCT03472365	Jiangsu HengRui Medicine Co., Ltd.	Gastric Cancer\|GastroEsophageal Cancer	April 2, 2018	Phase 2
NCT01804790	UNICANCER	Cancer of the Rectum	January 2012	Phase 3
NCT04158258	Hoffmann-La Roche\|Latin American Cooperative Oncology Group	Breast Cancer	February 21, 2020
NCT03435666	Qilu Pharmaceutical Co., Ltd.	Colon Cancer\|Breast Cancer	May 2018	Phase 1
NCT01267240	National Cancer Institute (NCI)	Paranasal Sinus Squamous Cell Carcinoma\|Recurrent Hypopharyngeal Squamous Cell Carcinoma\|Recurrent Laryngeal Squamous Cell Carcinoma\|Recurrent Oral Cavity Squamous Cell Carcinoma\|Recurrent Oropharyngeal Squamous Cell Carcinoma\|Stage IVA Hypopharyngeal Squamous Cell Carcinoma\|Stage IVA Laryngeal Squamous Cell Carcinoma\|Stage IVA Oral Cavity Squamous Cell Carcinoma\|Stage IVA Oropharyngeal Squamous Cell Carcinoma\|Stage IVB Hypopharyngeal Squamous Cell Carcinoma\|Stage IVB Laryngeal Squamous Cell Carcinoma\|Stage IVB Oral Cavity Squamous Cell Carcinoma\|Stage IVB Oropharyngeal Squamous Cell Carcinoma\|Stage IVC Hypopharyngeal Squamous Cell Carcinoma\|Stage IVC Laryngeal Squamous Cell Carcinoma\|Stage IVC Oral Cavity Squamous Cell Carcinoma\|Stage IVC Oropharyngeal Squamous Cell Carcinoma	December 2010	Phase 2
NCT01683422	Loma Linda University	Pancreatic Cancer	January 2, 2013	Not Applicable

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL ( 695.70 mM ; Need ultrasonic)

H ₂ O : ≥ 33.33 mg/mL ( 92.75 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7828 mL	13.9140 mL	27.8280 mL
5 mM	0.5566 mL	2.7828 mL	5.5656 mL
10 mM	0.2783 mL	1.3914 mL	2.7828 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: PBS

Solubility: 25 mg/mL (69.57 mM); Clear solution; Need ultrasonic
2.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.08 mg/mL (5.79 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.08 mg/mL (5.79 mM); Clear solution
4.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.08 mg/mL (5.79 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] PharmD CM, et al. Capecitabine: A review. Clinical Therapeutics. 2005 Jan; 27(1): 23-44.
[2] Guichard SM, et al. Gene expression predicts differential capecitabine metabolism, impacting on both pharmacokinetics and antitumour activity. Eur J Cancer. 2008 Jan;44(2):310-7.

Synonyms

Cytidine, 5′-deoxy-5-fluoro-N-[(pentyloxy)carbonyl]-

Carbamic acid, [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl]-, pentyl ester

5′-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine

Ro 09-1978/000

Capecitabine

Ro 09-1978

5′-Deoxy-5-fluoro-N⁴-(pentyloxycarbonyl)cytidine

Xeloda

Capecitibine

Capecytabine

Capiibine

Captabin

N⁴-Pentyloxycarbonyl-5′-deoxy-5-fluorocytidine

Capacetrine

Ecansya

Capecitabine Medac

Capecitabine Accord

Capecitabine Teva

Capecitabine SUN

Xeltabin

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