[CAS NO. 155521-45-2] Alisol F

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PRODUCTS SPECIFICATIONS [155521-45-2]

Catalog

HY-N0854

Brand

MCE

CAS

155521-45-2

DESCRIPTION [155521-45-2]

Overview

MDL	-
Molecular Weight	488.70
Molecular Formula	C30H48O5
SMILES	C[C@]1(C(C[C@@H]2O)=C([C@@H]3C)[C@](O[C@@]([C@@H](O)C(C)(O)C)([H])C3)([H])C1)[C@]([C@]2([H])[C@]4(CCC5=O)C)(CC[C@@]4([H])C5(C)C)C

For research use only. We do not sell to patients.

Summary

Alisol F is a triterpene isolated from Alisma orinentale , has immunosuppressive and anti-virus functions. Alisol F exhibits inhibitory activity in vitro on hepatitis B virus (HBV) surface antigen (HBsAg) secretion of the HepG2.2.15 cell line with an IC ₅₀ of 0.6 μM ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 204.62 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0462 mL	10.2312 mL	20.4625 mL
5 mM	0.4092 mL	2.0462 mL	4.0925 mL
10 mM	0.2046 mL	1.0231 mL	2.0462 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (5.12 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (5.12 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (5.12 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Zhi-Yong Jiang, et al. A new triterpene and anti-hepatitis B virus active compounds from Alisma orientalis.Planta Med