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[CAS NO. 1609281-86-8] AZD3264
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-19362 |
| Brand: | MCE |
| CAS: | 1609281-86-8 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 441.50 |
| Molecular Formula | C21H23N5O4S |
| SMILES | O=C(C1=C(NC(N)=O)SC(C2=CC=C(C3=C(C)ON=C3C)C=C2O[C@@H]4CNCC4)=C1)N |
2 Publications Citing Use of MCE
Summary
AZD3264 is a selective IkB-kinase IKK2 inhibitor.
IC50 & Target
|
IKK2
|
In Vivo
AZD3264 is a selective IkB-kinase IKK2 inhibitor, which is currently in preclinical development for the potential treatment of chronic pulmonary obstructive disorder (COPD) and asthma [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : ≥ 48 mg/mL ( 108.72 mM )
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.2650 mL | 11.3250 mL | 22.6501 mL |
| 5 mM | 0.4530 mL | 2.2650 mL | 4.5300 mL |
| 10 mM | 0.2265 mL | 1.1325 mL | 2.2650 mL |
-
1.
-
2.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.5 mg/mL (5.66 mM); Clear solution
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