[CAS NO. 16330-92-0] Tetrathiomolybdate
PRODUCTS SPECIFICATIONS [16330-92-0]
DESCRIPTION [16330-92-0]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 224.22 |
| Molecular Formula | MoS42- |
| SMILES | S=[Mo-2](=S)(=S)=S |
1 Publications Citing Use of MCE
Summary
Tetrathiomolybdate, an orally active anti-copper agent, reduces copper levels in the body. Tetrathiomolybdate has a protective effect on collagen-induced arthritis in mice. Tetrathiomolybdate also reduces blood sugar, but has no effect on mice with hereditary diabetes (db/db). Tetrathiomolybdate inhibit angiogenesis, also shows antiangiogenic effects in malignant pleural mesothelioma [1] [2] [3] .
In Vivo
Tetrathiomolybdate (0.2 mg/mouse/day; p.o.; for 10 weeks) protects mice from collagen-induced arthritis with preventive effect
[1]
.
Tetrathiomolybdate (0.03 mg/mL; medicined in water; p.o.; 8 weeks) inhibits the progress of collagen-induced arthritis in mice by reducing swelling and erythema
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
| Animal Model: | Collagen-induced arthritis model in mice [1] |
| Dosage: | 0.2 mg/mouse/day or 0.03 mg/mL, added in water |
| Administration: | Oral gavage, for 10 weeks; Collagen injected at weeks 2 |
| Result: | Showed significant preventive effect and protective effect in mice. |
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Synonyms