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[CAS NO. 1642839-27-7] GRK5-IN-2
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-136561 |
| Brand: | MCE |
| CAS: | 1642839-27-7 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 380.40 |
| Molecular Formula | C20H20N4O4 |
| SMILES | COC1=C(OC)C(OC)=CC(NC2=CC3=C(N=C(C4=CC=CO4)N3C)C=N2)=C1 |
Summary
GRK5-IN-2 (compound 707), a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor. GRK5-IN-2 regulates the expression and/or release of insulin and is useful for the metabolic disease research [1] .
IC50 & Target
GRK5 [1]
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 83.33 mg/mL ( 219.06 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.6288 mL | 13.1441 mL | 26.2881 mL |
| 5 mM | 0.5258 mL | 2.6288 mL | 5.2576 mL |
| 10 mM | 0.2629 mL | 1.3144 mL | 2.6288 mL |
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1.
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