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[CAS NO. 1670-87-7] SD-169
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-W015445 |
| Brand: | MCE |
| CAS: | 1670-87-7 |
Overview
| MDL | MFCD07779486 |
|---|---|
| Molecular Weight | 160.18 |
| Molecular Formula | C9H8N2O |
| SMILES | O=C(C1=CC2=C(NC=C2)C=C1)N |
Summary
IC50 & Target
|
p38α MAPK 3.2 nM (IC 50 ) |
p38β MAPK 122 nM (IC 50 ) |
In Vitro
SD-169 significantly reduces p38 and HSP60 expression in T cells of the pancreatic beta islets
[1]
.
SD-169 demonstrates 38-fold potency against p38α MAP kinase (IC
50
=3.2 nM) than p38β MAP kinase (IC
50
=122 nM)
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL ( 624.30 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 6.2430 mL | 31.2149 mL | 62.4298 mL |
| 5 mM | 1.2486 mL | 6.2430 mL | 12.4860 mL |
| 10 mM | 0.6243 mL | 3.1215 mL | 6.2430 mL |
Synonyms
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