[CAS NO. 1849616-42-7]  ALC-0159

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PRODUCTS SPECIFICATIONS [1849616-42-7]

Catalog
HY-138300
Brand
MCE
CAS
1849616-42-7

DESCRIPTION [1849616-42-7]

Overview

MDL-
Molecular Weight-
Molecular Formula(C2H4O)nC31H63NO2
SMILESCCCCCCCCCCCCCCN(C(COCCOC)=O)CCCCCCCCCCCCCC.[n]

For research use only. We do not sell to patients.

Summary

ALC-0159, a polyethylene glycol (PEG) lipid conjugate, could be used as vaccine excipient [1] .


In Vitro

ALC-0159, which contributes to nanoparticle stabilization by a steric mechanism through its poly(ethylene glycol) (PEG) moiety [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (Need ultrasonic)

Ethanol : ≥ 50 mg/mL

* "≥" means soluble, but saturation unknown.

In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (Infinity mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (Infinity mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (Infinity mM); Clear solution

* All of the co-solvents are available by MCE.