[CAS NO. 185517-21-9] Arundic Acid

Ships within

Stock

Price

Qty

Total

$0.00

Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis

request a quote

If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [185517-21-9]

Catelog

HY-107661

Brand

MCE

CAS

185517-21-9

DESCRIPTION [185517-21-9]

Overview

MDL	MFCD08458423
Molecular Weight	186.29
Molecular Formula	C11H22O2
SMILES	CCCCCC[C@H](C(O)=O)CCC

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE

[1]Int Immunopharmacol. 2021 May 26;97:107792.

Summary

Arundic acid (ONO-2506) is an astrocyte-modulating agent, which delays the expansion of cerebral infarcts by modulating the activation of astrocytes through inhibition of S-100β synthesis. Arundic acid has the potential for stroke and Alzheimer’s disease research ^[1] ^[2] ^[3] .

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase
NCT00229177	Ono Pharmaceutical Co. Ltd	Stroke	September 2005	Phase 2\|Phase 3
NCT00046761	Ono Pharma USA Inc\|Ono Pharmaceutical Co. Ltd	Cerebrovascular Accident	November 2002	Phase 2\|Phase 3

Appearance

Liquid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 150 mg/mL ( 805.20 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.3680 mL	26.8399 mL	53.6797 mL
5 mM	1.0736 mL	5.3680 mL	10.7359 mL
10 mM	0.5368 mL	2.6840 mL	5.3680 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: 3.75 mg/mL (20.13 mM); Suspended solution; Need ultrasonic
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 3.75 mg/mL (20.13 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 3.75 mg/mL (20.13 mM); Clear solution

* All of the co-solvents are available by MCE.