[CAS NO. 1998705-62-6]  HCV-IN-31

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PRODUCTS SPECIFICATIONS [1998705-62-6]

Catalog
HY-138305
Brand
MCE
CAS
1998705-62-6

DESCRIPTION [1998705-62-6]

Overview

MDL-
Molecular Weight312.30
Molecular FormulaC12H17FN6O3
SMILESOC[C@@H]1[C@@H](O)[C@](F)(C)[C@H](N2C3=NC(N)=NC(NC)=C3N=C2)O1

For research use only. We do not sell to patients.

Summary

HCV-IN-31 (compound 4) is a HCV inhibitor, with an EC 50 /EC 95 of 15.7 μM for HCV replicon [1] .


IC50 & Target

EC50/EC95: 15.7 μM (HCV replicon) [1] .


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 60 mg/mL ( 192.12 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2020 mL 16.0102 mL 32.0205 mL
5 mM 0.6404 mL 3.2020 mL 6.4041 mL
10 mM 0.3202 mL 1.6010 mL 3.2020 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (8.01 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (8.01 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (8.01 mM); Clear solution

* All of the co-solvents are available by MCE.