[CAS NO. 20559-16-4] LysoPC(14:0/0:0)

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PRODUCTS SPECIFICATIONS [20559-16-4]

Catalog

HY-113123

Brand

MCE

CAS

20559-16-4

DESCRIPTION [20559-16-4]

Overview

MDL	MFCD00036902
Molecular Weight	467.58
Molecular Formula	C22H46NO7P
SMILES	CCCCCCCCCCCCCC(OC[C@@H](O)COP(OCC[N+](C)(C)C)([O-])=O)=O

For research use only. We do not sell to patients.

Summary

LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect ^[1] .

IC50 & Target

Human Endogenous Metabolite

In Vivo

Of the saturated fatty acid-containing L-α-lysolecithins (LPC), palmitoyl-LPC shows the strongest antispasmodic effect against acetylcholine- or histamine-induced guinea pig ileum contraction; the order of potency of the others is (LysoPC(14:0/0:0)) myristoyl- > stearoyl-, lauroyl- > decanoyl-LPC. Incorporation of a cis-double bond into the C18 fatty acid chain of LPC resulted in a slight decrease of the antispasmodic effect ^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

Ethanol : 50 mg/mL ( 106.93 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1387 mL	10.6934 mL	21.3867 mL
5 mM	0.4277 mL	2.1387 mL	4.2773 mL
10 mM	0.2139 mL	1.0693 mL	2.1387 mL

* Please refer to the solubility information to select the appropriate solvent.

References

[1] Tsukatani H, et al.Comparison of antispasmodic effect of synthetic lysolecithins with various fatty acid moieties on guinea pig ileum.J Pharmacobiodyn. 1984 Jun;7(6):400-6.

Synonyms

3,5,9-Trioxa-4-phosphatricosan-1-aminium, 4,7-dihydroxy-N,N,N-trimethyl-10-oxo-, inner salt, 4-oxide, (7R)-

Choline, hydroxide, dihydrogen phosphate, inner salt, 3-ester with 1-monomyristin, L-

3,5,9-Trioxa-4-phosphatricosan-1-aminium, 4,7-dihydroxy-N,N,N-trimethyl-10-oxo-, inner salt, 4-oxide, (R)-

Myristin, 1-mono-, 3-(dihydrogen phosphate), monoester with choline hydroxide, inner salt, L-

Myristoyl L-α-lysolecithin

L-α-Myristoyllysophosphatidylcholine

1-Tetradecanoyl-sn-glycero-3-phosphorylcholine

1-Myristoyl-L-α-phosphorylcholine

1-Myristoyl-sn-glycero-3-phosphatidylcholine

Myristoyl L-α-lysophosphatidylcholine

1-Myristoyl-sn-glycero-3-phosphocholine

Coatsome MC 40H

M-LysoPC

1-Myristoyl-2-hydroxy-sn-glycero-3-phosphocholine

1-Tetradecanoyl-sn-glycero-3-phosphocholine

Lysophosphatidylcholine (14:0)

LysoPC(14:0)

Lysophosphatidylcholine C14:0

LPC 14:0

[(2R)-2-Hydroxy-3-tetradecanoyloxypropyl] 2-(trimethylazaniumyl)ethyl phosphate