[CAS NO. 2089-82-9] sAJM589
PRODUCTS SPECIFICATIONS [2089-82-9]
DESCRIPTION [2089-82-9]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 246.26 |
| Molecular Formula | C16H10N2O |
| SMILES | OC1=CC2=NC3=CC=CC=C3N=C2C4=CC=CC=C41 |
1 Publications Citing Use of MCE
Summary
sAJM589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC 50 of 1.8 μM [1] .
IC50 & Target
IC50: 1.8 μM (Myc) [1]
In Vitro
sAJM589 potently disrupts the Myc-Max heterodimer to reduce Myc protein levels in a dose dependent manner, with an IC
50
of 1.8 μM
[1]
.
sAJM589 suppresses cellular proliferation in diverse Myc-dependent cancer cell lines and anchorage independent growth of Raji cells
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 5 mg/mL ( 20.30 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 4.0607 mL | 20.3037 mL | 40.6075 mL |
| 5 mM | 0.8121 mL | 4.0607 mL | 8.1215 mL |
| 10 mM | 0.4061 mL | 2.0304 mL | 4.0607 mL |