[CAS NO. 2101626-26-8] HPGDSinhibitor2

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PRODUCTS SPECIFICATIONS [2101626-26-8]

Catalog

HY-126134

Brand

MCE

CAS

2101626-26-8

MDL	MFCD32067944
Molecular Weight	378.41
Molecular Formula	C20H24F2N2O3
SMILES	FC(F)OC1=CC=C2C(N=CC(C(N[C@@H]3CC[C@@H](C(C)(C)O)CC3)=O)=C2)=C1

For research use only. We do not sell to patients.

HPGDS inhibitor 2 is a highly potent and selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with an IC ₅₀ of 9.9 nM ^[1] .

IC50: 9.9 nM (H-PGDS) ^[1]

Solid

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

In Vitro:

DMSO : ≥ 150 mg/mL ( 396.40 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (6.61 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (6.61 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (6.61 mM); Clear solution

* All of the co-solvents are available by MCE.