[CAS NO. 2135304-43-5] KHK-IN-2

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PRODUCTS SPECIFICATIONS [2135304-43-5]

Catalog

HY-103478

Brand

MCE

CAS

2135304-43-5

MDL	-
Molecular Weight	372.34
Molecular Formula	C16H19F3N4O3
SMILES	N#CC1=C(C(F)(F)F)C=C(N2C[C@H](O)[C@@H](O)C2)N=C1N3CC[C@](C)(O)C3

For research use only. We do not sell to patients.

KHK-IN-2 is a potent and selective ketohexokinase (KHK) inhibitor with an IC ₅₀ of 0.45 μM.

IC50: 0.45 μM (KHK) ^[1]

Solid

Room temperature in continental US; may vary elsewhere.

In Vitro:

DMSO : 250 mg/mL ( 671.43 mM ; Need ultrasonic)

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Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.08 mg/mL (5.59 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.08 mg/mL (5.59 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.08 mg/mL (5.59 mM); Clear solution

* All of the co-solvents are available by MCE.