[CAS NO. 2139348-63-1] Pomalidomide4'-PEG5-acid
PRODUCTS SPECIFICATIONS [2139348-63-1]
DESCRIPTION [2139348-63-1]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 565.57 |
| Molecular Formula | C26H35N3O11 |
| SMILES | O=C(O)CCOCCOCCOCCOCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O |
Summary
IC50 & Target
|
Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
H 2 O : 50 mg/mL ( 88.41 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.7681 mL | 8.8406 mL | 17.6813 mL |
| 5 mM | 0.3536 mL | 1.7681 mL | 3.5363 mL |
| 10 mM | 0.1768 mL | 0.8841 mL | 1.7681 mL |