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[CAS NO. 2143452-22-4] TSHRantagonistS37b
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-129995 |
| Brand: | MCE |
| CAS: | 2143452-22-4 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 460.57 |
| Molecular Formula | C25H20N2O3S2 |
| SMILES | O=C(N1)SC([C@@H]2C3=CC=CC=C3)=C1S[C@]([C@]2([H])[C@]4([H])[C@]56[H])([H])[C@@](C4)([H])[C@@]6([H])C(N(C7=CC=CC=C7)C5=O)=O |
Summary
TSHR antagonist S37b is the less effective enantiomer of TSHR antagonist S37a (HY-129995A). TSHR antagonist S37b shows only a minor effect for thyrotropin receptor (TSHR) inhibition. TSHR antagonist S37b can be used for the research of thyroid function [1] .
IC50 & Target
TSHR [1]
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 217.12 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.1712 mL | 10.8561 mL | 21.7122 mL |
| 5 mM | 0.4342 mL | 2.1712 mL | 4.3424 mL |
| 10 mM | 0.2171 mL | 1.0856 mL | 2.1712 mL |
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