Your shopping cart is empty!
Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
Catalog: | HY-N3014 |
Brand: | MCE |
CAS: | 21499-66-1 |
MDL | MFCD00221753 |
---|---|
Molecular Weight | 410.42 |
Molecular Formula | C20H26O9 |
SMILES | O[C@@]1([C@H]2O)[C@@]34[C@@]([C@@H](O)[C@H](O)[C@]1(OC4)C)([H])[C@]([C@@](C(C)=CC5=O)([H])C[C@@]3([H])OC2=O)([C@@H]5O)C |
Bruceine D is a Notch inhibitor with anti-cancer activity and induces apoptosis in several human cancer cells. Bruceine D is an effective botanical insect antifeedant with outstanding systemic properties, causing potent pest growth inhibitory activity [1] [2] . Bruceine D has strong anthelmintic activity against D. intermedius with an EC 50 value of 0.57 mg/L [3] .
Notch [1]
Bruceine D inhibits the cell viability of H460 and A549 cells in a dose-dependent manner with IC
50
values of 0.5 and 0.6 μM, respectively, at 48 h of treatment
[1]
.
Bruceine D (0.125-1.0 μM) dose-dependently promotes chromatin condensation, Annexin V-positive cell population and caspase-dependent apoptosis in H460 and A549 cells
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Solid
Room temperature in continental US; may vary elsewhere.
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
DMSO : 100 mg/mL ( 243.65 mM ; Need ultrasonic)
Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
---|
1 mM | 2.4365 mL | 12.1826 mL | 24.3653 mL |
5 mM | 0.4873 mL | 2.4365 mL | 4.8731 mL |
10 mM | 0.2437 mL | 1.2183 mL | 2.4365 mL |
Arctom is a premier supply platform offering over 600K unique items of Building Blocks, Bioactive Molecules, Natural Products, ADC PEG Linkers, Antibodies, and other Research Chemicals for global pharmaceutical, biotech, university, and industrial customers. We accelerate your research by providing better and faster purchasing experience & services.