[CAS NO. 216974-75-3] Bevacizumab

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Catalog:	HY-P9906
Brand:	MCE
CAS:	216974-75-3

Overview

MDL	-
Molecular Weight	149 kDa(Average)
Molecular Formula	-
SMILES	[Bevacizumab]

For research use only. We do not sell to patients.

15 Publications Citing Use of MCE

[1]J Extracell Vesicles. 2019 Jun 17;8(1):1629865.
[2]Cell Death Dis. 2020 Jan 23;11(1):55.
[3]PLoS Pathog. 2023 Jan 18;19(1):e1011077.
[4]Anal Chim Acta. 2021, 338306.
[5]EBioMedicine. 2019 Sep.
[6]Mol Carcinog. 2019 Dec;58(12):2316-2326.
[7]Nucleic Acid Ther. 2020 Dec;30(6):365-378.
[8]Int J Biol Sci. 2022; 18(3): 942-955.
[9]Int J Biol Sci. 2022; 18(3):942-955.
[10]Vascul Pharmacol. 2022 Nov 6;147:107126.
[11]Sci Rep. 2019 Nov 18;9(1):16954.
[12]J Ethnopharmacol. 2021 Sep 28;114667.
[13]J Pharmaceut Biomed. 2021, 114015.
[14]Research Square Print. 2022 Jun.
[15]Research Square Preprint. 2020 Jun.

Summary

Bevacizumab, a humanized IgG1 monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity.

IC50 & Target

VEGF ^[1]

In Vitro

Bevacizumab, a humanized monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity, and inhibits its interaction with VEGFR-1 and VEGFR-2 ^[1] . Experimental analysis shows that the EC ₅₀ of Bevacizumab to bind VEGF analyzed by ELISA is 0.18 μg/mL. Binding kinetics assays show similar results that Bevacizumab inhibits the VEGF-induced proliferation of HUVEC with an IC ₅₀ value of 0.047±0.0081 μg/mL ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

It is demonstrated that the subconjunctival administration of FD006 and Bevacizumab can significantly inhibit CoNV in NaOH cauterized rats compared with the control group (p < 0.01) ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase
NCT00482495	Mayo Clinic\|National Cancer Institute (NCI)	Multiple Myeloma and Plasma Cell Neoplasm	April 2006	Phase 2
NCT04843943	Fudan University	Hepatocellular Carcinoma	May 1, 2021	Phase 1\|Phase 2
NCT03476798	University of Oklahoma\|Clovis Oncology, Inc.	Cervical Cancer\|Endometrial Cancer	June 29, 2018	Phase 2
NCT04230187	Yanhong Deng\|Sun Yat-sen University	Colorectal Cancer	June 1, 2020	Phase 3
NCT00445848	Southwest Oncology Group\|National Cancer Institute (NCI)	Lung Cancer	July 2007	Phase 2
NCT03890952	Ulrik Lassen\|Herlev Hospital\|University of Copenhagen\|Rigshospitalet, Denmark	Recurrent Adult Brain Tumor	October 1, 2018	Phase 2
NCT02069704	mAbxience Research S.L.\|Laboratorio Elea Phoenix S.A.\|Libbs Farmacêutica LTDA	Metastatic Colorectal Cancer (mCRC)	October 29, 2014	Phase 1
NCT00602329	Abramson Cancer Center of the University of Pennsylvania\|National Cancer Institute (NCI)	Colorectal Cancer	February 2006	Phase 2
NCT01256580	Massachusetts Eye and Ear Infirmary	Choroidal Neovascularization\|Myopia\|Punctate Inner Choroidopathy (PIC)\|Multifocal Choroiditis\|Ocular Histoplasmosis Syndrome\|Central Serous Chorioretinopathy (CSC)\|Angioid Streaks\|Trauma, or Hereditary Eye Diseases	August 2010	Not Applicable
NCT01526837	Brain & Spine Surgeons of New York	Glioblastoma Multiforme	October 2011	Phase 1
NCT00741221	Hellenic Oncology Research Group	Non-small-cell Lung Cancer	June 2008	Phase 2
NCT00762034	Eli Lilly and Company	Non-small Cell Lung Cancer	December 2008	Phase 3
NCT00250978	Memorial Sloan Kettering Cancer Center	Carcinoma, Non-Small-Cell Lung	November 2005	Phase 1
NCT01891747	Vanderbilt-Ingram Cancer Center	Malignant Glioma	July 2013	Phase 1
NCT00479674	Duke University\|Genentech, Inc.\|Celgene Corporation	Breast Cancer	May 2007	Phase 2
NCT01506167	Hoffmann-La Roche	Colorectal Cancer	July 6, 2012
NCT00745498	Seoul National University Bundang Hospital	Proliferative Diabetic Retinopathy\|Vitreous Hemorrhage	June 2008	Not Applicable
NCT03394885	Duke University\|Johns Hopkins University\|Genentech, Inc.	Ovarian Cancer\|Ovarian Neoplasms	June 19, 2018	Phase 1\|Phase 2
NCT00703976	University of Pittsburgh\|Eli Lilly and Company\|Genentech, Inc.	Cancer	October 2008	Phase 2
NCT01010126	National Cancer Institute (NCI)	Adult Hepatocellular Carcinoma\|Advanced Adult Hepatocellular Carcinoma\|Endometrial Serous Adenocarcinoma\|Localized Non-Resectable Adult Liver Carcinoma\|Lung Carcinoid Tumor\|Malignant Pancreatic Gastrinoma\|Malignant Pancreatic Glucagonoma\|Malignant Pancreatic Insulinoma\|Malignant Pancreatic Somatostatinoma\|Metastatic Digestive System Neuroendocrine Tumor G1\|Ovarian Carcinosarcoma\|Ovarian Endometrioid Adenocarcinoma\|Ovarian Seromucinous Carcinoma\|Ovarian Serous Surface Papillary Adenocarcinoma\|Pancreatic Alpha Cell Adenoma\|Pancreatic Beta Cell Adenoma\|Pancreatic Delta Cell Adenoma\|Pancreatic G-Cell Adenoma\|Pancreatic Polypeptide Tumor\|Recurrent Adult Liver Carcinoma\|Recurrent Digestive System Neuroendocrine Tumor G1\|Recurrent Fallopian Tube Carcinoma\|Recurrent Ovarian Carcinoma\|Recurrent Pancreatic Neuroendocrine Carcinoma\|Recurrent Primary Peritoneal Carcinoma\|Recurrent Uterine Corpus Carcinoma\|Regional Digestive System Neuroendocrine Tumor G1\|Stage IIIA Fallopian Tube Cancer\|Stage IIIA Ovarian Cancer\|Stage IIIA Primary Peritoneal Cancer\|Stage IIIA Uterine Corpus Cancer\|Stage IIIB Fallopian Tube Cancer\|Stage IIIB Ovarian Cancer\|Stage IIIB Primary Peritoneal Cancer\|Stage IIIB Uterine Corpus Cancer\|Stage IIIC Fallopian Tube Cancer\|Stage IIIC Ovarian Cancer\|Stage IIIC Primary Peritoneal Cancer\|Stage IIIC Uterine Corpus Cancer\|Stage IV Fallopian Tube Cancer\|Stage IV Ovarian Cancer\|Stage IV Primary Peritoneal Cancer\|Stage IVA Uterine Corpus Cancer\|Stage IVB Uterine Corpus Cancer\|Uterine Carcinosarcoma	September 8, 2009	Phase 2
NCT01661283	Sarcoma Alliance for Research through Collaboration\|Novartis Pharmaceuticals\|Genentech, Inc.\|United States Department of Defense	Malignant Peripheral Nerve Sheath Tumors\|MPNST\|Sarcoma	September 2012	Phase 2
NCT00700102	Hoffmann-La Roche	Colorectal Cancer	February 2006	Phase 3
NCT02310295	University of Sao Paulo	Diabetic Macular Edema	January 2009	Not Applicable
NCT01219205	Hallym University Medical Center	Macular Edema	March 2008	Not Applicable
NCT01966003	Amgen\|Actavis Inc.	Non-small Cell Lung Cancer Metastatic	November 11, 2013	Phase 3
NCT05410301	Varun Monga, MD\|University of Iowa	Glioblastoma\|Recurrent Glioblastoma	April 2023	Not Applicable
NCT02330783	Peking University Cancer Hospital & Institute	Metastatic Renal Cell Carcinoma	December 2014	Phase 2
NCT00906685	Anders Kvanta\|St. Erik Eye Hospital	Central Retinal Vein Occlusion	May 2009	Phase 3
NCT00217672	Translational Oncology Research International\|University of California, Los Angeles	Breast Cancer	May 2005	Phase 2
NCT00240071	University of Alabama at Birmingham\|Genentech, Inc.	Metastatic Breast Cancer	October 2005	Phase 2
NCT01677884	Gustave Roussy, Cancer Campus, Grand Paris	Colorectal Neoplasms	November 2012	Phase 2
NCT00307736	Massachusetts General Hospital\|Beth Israel Deaconess Medical Center\|Dana-Farber Cancer Institute\|Genentech, Inc.	Rectal Cancer\|Adenocarcinoma of the Rectum	May 2006	Phase 1\|Phase 2
NCT00577031	Hoffmann-La Roche	Colorectal Cancer	February 2008	Phase 4
NCT05271240	Northwell Health	Glioblastoma\|Glioblastoma Multiforme\|Glioma, Malignant\|GBM\|Brain Cancer\|Glioblastoma, IDH-wildtype\|Glioblastoma Multiforme, Adult	April 27, 2022	Phase 3
NCT05062317	M.D. Anderson Cancer Center	Liver Metastases	April 26, 2022	Phase 2
NCT03872947	Toray Industries, Inc	Solid Tumor\|Colorectal Cancer\|Cholangiocarcinoma\|Bladder Cancer\|Ovarian Cancer\|Gastric Cancer\|Palpable Subcutaneous Malignant Lesions\|Renal Cell Carcinoma\|Melanoma\|Epithelial Ovarian Cancer\|Primary Peritoneal Cancer\|Fallopian Tube Cancer	April 26, 2019	Phase 1
NCT02086656	Fondazione IRCCS Istituto Nazionale dei Tumori, Milano	Colorectal Cancer Liver Metastases	June 2013	Phase 2
NCT01075464	Genentech, Inc.	Solid Cancers	February 2010	Phase 1
NCT00440973	The Methodist Hospital Research Institute\|Genentech, Inc.	Carcinoma, Renal Cell	October 2006	Phase 2
NCT00898417	ECOG-ACRIN Cancer Research Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Lung Cancer	March 14, 2008
NCT01081262	National Cancer Institute (NCI)\|NRG Oncology	Borderline Ovarian Mucinous Tumor\|Ovarian Mucinous Cystadenocarcinoma\|Recurrent Fallopian Tube Carcinoma\|Recurrent Ovarian Carcinoma\|Stage IA Fallopian Tube Cancer AJCC v6 and v7\|Stage IA Ovarian Cancer AJCC v6 and v7\|Stage IB Fallopian Tube Cancer AJCC v6 and v7\|Stage IB Ovarian Cancer AJCC v6 and v7\|Stage IC Fallopian Tube Cancer AJCC v6 and v7\|Stage IC Ovarian Cancer AJCC v6 and v7\|Stage IIA Fallopian Tube Cancer AJCC v6 and v7\|Stage IIA Ovarian Cancer AJCC V6 and v7\|Stage IIB Fallopian Tube Cancer AJCC v6 and v7\|Stage IIB Ovarian Cancer AJCC v6 and v7\|Stage IIC Fallopian Tube Cancer AJCC v6 and v7\|Stage IIC Ovarian Cancer AJCC v6 and v7\|Stage IIIA Fallopian Tube Cancer AJCC v7\|Stage IIIA Ovarian Cancer AJCC v6 and v7\|Stage IIIB Fallopian Tube Cancer AJCC v7\|Stage IIIB Ovarian Cancer AJCC v6 and v7\|Stage IIIC Fallopian Tube Cancer AJCC v7\|Stage IIIC Ovarian Cancer AJCC v6 and v7\|Stage IV Fallopian Tube Cancer AJCC v6 and v7\|Stage IV Ovarian Cancer AJCC v6 and v7	October 12, 2010	Phase 3
NCT03577743	Assiut University	Metastatic Triple Negative Breast Cancer\|Safety Issues\|Efficacy	July 1, 2018	Phase 2
NCT02853318	Roswell Park Cancer Institute	Fallopian Tube Clear Cell Adenocarcinoma\|Fallopian Tube Endometrioid Adenocarcinoma\|Fallopian Tube Mucinous Adenocarcinoma\|Fallopian Tube Serous Adenocarcinoma\|Ovarian Clear Cell Adenocarcinoma\|Ovarian Endometrioid Adenocarcinoma\|Ovarian Mucinous Adenocarcinoma\|Ovarian Serous Adenocarcinoma\|Primary Peritoneal Serous Adenocarcinoma\|Recurrent Fallopian Tube Carcinoma\|Recurrent Ovarian Carcinoma\|Recurrent Primary Peritoneal Carcinoma\|Undifferentiated Fallopian Tube Carcinoma\|Undifferentiated Ovarian Carcinoma	September 1, 2016	Phase 2
NCT03176264	Novartis Pharmaceuticals\|Novartis	Metastatic Colorectal Cancer	September 25, 2017	Phase 1
NCT02659384	European Organisation for Research and Treatment of Cancer - EORTC	Ovarian Neoplasms	December 2016	Phase 2
NCT00061178	Genentech, Inc.	Renal Cell Cancer		Phase 3
NCT00403442	Vitreous -Retina- Macula Consultants of New York\|QLT Inc.	Macular Degeneration	September 2006	Phase 1
NCT03721653	Gruppo Oncologico del Nord-Ovest\|Roche Pharma AG	Metastatic Colorectal Cancer	November 30, 2018	Phase 2
NCT00942331	National Cancer Institute (NCI)	Advanced Urothelial Carcinoma\|Metastatic Bladder Urothelial Carcinoma\|Metastatic Prostate Carcinoma\|Metastatic Renal Pelvis Urothelial Carcinoma\|Metastatic Ureter Urothelial Carcinoma\|Metastatic Urethral Urothelial Carcinoma\|Metastatic Urothelial Carcinoma\|Stage IV Bladder Urothelial Carcinoma AJCC v7\|Stage IV Prostate Cancer AJCC v7\|Stage IV Renal Pelvis Cancer AJCC v7\|Stage IV Ureter Cancer AJCC v7\|Stage IV Urethral Cancer AJCC v7\|Unresectable Urothelial Carcinoma	July 15, 2009	Phase 3
NCT03186326	Federation Francophone de Cancerologie Digestive	Metastatic Colorectal Cancer\|MSI	April 24, 2018	Phase 2
NCT00601900	National Cancer Institute (NCI)	Invasive Breast Carcinoma\|Recurrent Breast Carcinoma\|Stage III Breast Cancer AJCC v6\|Stage IV Breast Cancer AJCC v6 and v7	May 15, 2008	Phase 3
NCT01139723	Genentech, Inc.	Solid Cancers	June 2010	Phase 1
NCT00344617	Singapore National Eye Centre	Choroidal Neovascularisation\|Polypoidal Choroidal Vasculopathy	June 2006	Phase 3
NCT01399918	Memorial Sloan Kettering Cancer Center\|Novartis Pharmaceuticals	Renal Cell Carcinoma	July 2011	Phase 2
NCT04683965	The First Affiliated Hospital with Nanjing Medical University\|Jiangsu Hansoh Pharmaceutical Co., Ltd.	Colorectal Neoplasms	January 1, 2021	Phase 2
NCT05007132	Dominik Paul Modest\|Charite University, Berlin, Germany	Metastatic Colorectal Cancer	December 17, 2021	Phase 2
NCT02921269	National Cancer Institute (NCI)	Cervical Adenocarcinoma\|Cervical Adenosquamous Carcinoma\|Cervical Squamous Cell Carcinoma, Not Otherwise Specified\|Recurrent Cervical Carcinoma\|Stage IV Cervical Cancer AJCC v6 and v7\|Stage IVA Cervical Cancer AJCC v6 and v7\|Stage IVB Cervical Cancer AJCC v6 and v7	March 10, 2017	Phase 2
NCT00294359	Australasian Gastro-Intestinal Trials Group	Metastatic Colorectal Cancer	June 2005	Phase 2\|Phase 3
NCT04854668	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.	Metastatic Colorectal Cancer	May 27, 2021	Phase 3
NCT04776655	Azienda Unità Sanitaria Locale Reggio Emilia\|Istituto Di Ricerche Farmacologiche Mario Negri\|Istituto Nazionale Tumori IRCCS - Fondazione G. Pascale	Colorectal Cancer\|Metastatic Colorectal Cancer\|RAS Mutation	April 30, 2021	Phase 3
NCT00463073	Rigshospitalet, Denmark\|Aalborg University Hospital\|Odense University Hospital	Malignant Gliomas	August 2006	Phase 2
NCT01614509	Yeungnam University College of Medicine	Branch Retinal Vein Occlusion	January 2012	Not Applicable
NCT01051583	Cairo University\|AL-Nour Eye Hospital\|Kasr El Aini Hospital	Neovascular Glaucoma	January 2006	Phase 2
NCT03743428	Shenzhen People´s Hospital	Colorectal Neoplasms	October 22, 2020	Not Applicable
NCT00113230	M.D. Anderson Cancer Center\|Genentech, Inc.	Rectal Cancer	February 2005	Phase 2
NCT03095001	Chinese PLA General Hospital	Peritoneal Adhesion	June 1, 2017	Phase 2
NCT00022048	Stanford University\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	August 2001	Phase 1\|Phase 2
NCT00868192	Washington University School of Medicine\|Columbia University	Ovarian Carcinoma\|Primary Peritoneal Carcinoma	May 2008	Phase 2
NCT01397695	University of California, San Diego	Hereditary Hemorrhagic Telangiectasia (HHT)	June 2009	Phase 2
NCT01847677	Grupo Español de Investigación en Cáncer de Ovario\|Roche Pharma AG	Cancer, Ovarian	May 6, 2013	Phase 2
NCT04607421	Pfizer\|Ono Pharmaceutical Co. Ltd\|Merck KGaA, Darmstadt, Germany	Neoplasms	December 21, 2020	Phase 3
NCT01375816	GERCOR - Multidisciplinary Oncology Cooperative Group	Colorectal Cancer	May 2011	Phase 2
NCT00255762	National Cancer Institute (NCI)	Recurrent Melanoma\|Stage IV Melanoma	December 2005	Phase 2
NCT01327222	IRCCS San Raffaele	Age Related Macular Degeneration	February 2011	Phase 3
NCT03878524	OHSU Knight Cancer Institute\|Oregon Health and Science University	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Anatomic Stage IV Breast Cancer AJCC v8\|Anemia\|Ann Arbor Stage III Hodgkin Lymphoma\|Ann Arbor Stage III Non-Hodgkin Lymphoma\|Ann Arbor Stage IV Hodgkin Lymphoma\|Ann Arbor Stage IV Non-Hodgkin Lymphoma\|Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative\|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Castration-Resistant Prostate Carcinoma\|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Hematopoietic and Lymphoid System Neoplasm\|Locally Advanced Pancreatic Adenocarcinoma\|Metastatic Breast Carcinoma\|Metastatic Malignant Solid Neoplasm\|Metastatic Pancreatic Adenocarcinoma\|Myelodysplastic+Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Primary Myelofibrosis\|Recurrent Acute Lymphoblastic Leukemia\|Recurrent Acute Myeloid Leukemia\|Recurrent Chronic Lymphocytic Leukemia\|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Recurrent Hematologic Malignancy\|Recurrent Hodgkin Lymphoma\|Recurrent Myelodysplastic Syndrome\|Recurrent Myelodysplastic+Myeloproliferative Neoplasm\|Recurrent Myeloproliferative Neoplasm\|Recurrent Non-Hodgkin Lymphoma\|Recurrent Plasma Cell Myeloma\|Recurrent Small Lymphocytic Lymphoma\|Refractory Acute Lymphoblastic Leukemia\|Refractory Acute Myeloid Leukemia\|Refractory Chronic Lymphocytic Leukemia\|Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Refractory Chronic Myelomonocytic Leukemia\|Refractory Hematologic Malignancy\|Refractory Hodgkin Lymphoma\|Refractory Malignant Solid Neoplasm\|Refractory Myelodysplastic Syndrome\|Refractory Myelodysplastic+Myeloproliferative Neoplasm\|Refractory Non-Hodgkin Lymphoma\|Refractory Plasma Cell Myeloma\|Refractory Primary Myelofibrosis\|Refractory Small Lymphocytic Lymphoma\|Stage II Pancreatic Cancer AJCC v8\|Stage III Pancreatic Cancer AJCC v8\|Stage IV Pancreatic Cancer AJCC v8\|Stage IV Prostate Cancer AJCC v8\|Unresectable Pancreatic Adenocarcinoma	April 1, 2020	Phase 1
NCT01860144	Peking University	Metastatic Colorectal Cancer	June 2012
NCT00265850	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)\|Southwest Oncology Group\|Bristol-Myers Squibb\|Aptuit Inc.	Colorectal Cancer	November 2005	Phase 3
NCT00884741	National Cancer Institute (NCI)\|Radiation Therapy Oncology Group\|NRG Oncology	Glioblastoma\|Gliosarcoma\|Supratentorial Glioblastoma	April 15, 2009	Phase 3
NCT00662129	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Breast Cancer	November 2008	Phase 2
NCT04305106	Qilu Hospital of Shandong University\|Renmin Hospital of Wuhan University\|Ialy Moriggia Pelascini Gravedona Hospital S.p.A\|Wuhan University\|Jiangbei Union Hospital of Huazhong University of science and technology\|Shandong Provincial Chest Hospital	COVID-19 Pneumonia	March 17, 2020	Not Applicable
NCT00193622	SCRI Development Innovations, LLC\|Genentech, Inc.	Neoplasms, Unknown Primary	April 2004	Phase 2
NCT04175470	Vejle Hospital	Ovarian Cancer Recurrent	October 29, 2019	Phase 2
NCT00473590	Genentech, Inc.	Multiple Myeloma	June 2007	Phase 2
NCT00989651	National Cancer Institute (NCI)\|NRG Oncology	Fallopian Tube Carcinoma\|Fallopian Tube Carcinosarcoma\|Fallopian Tube Clear Cell Adenocarcinoma\|Fallopian Tube Endometrioid Adenocarcinoma\|Fallopian Tube Mucinous Adenocarcinoma\|Fallopian Tube Serous Neoplasm\|Fallopian Tube Transitional Cell Carcinoma\|Fallopian Tube Undifferentiated Carcinoma\|Ovarian Brenner Tumor\|Ovarian Carcinoma\|Ovarian Carcinosarcoma\|Ovarian Clear Cell Adenocarcinoma\|Ovarian Endometrioid Adenocarcinoma\|Ovarian Mucinous Adenocarcinoma\|Ovarian Seromucinous Tumor\|Ovarian Serous Adenocarcinoma\|Ovarian Transitional Cell Carcinoma\|Ovarian Undifferentiated Carcinoma\|Primary Peritoneal Carcinoma\|Primary Peritoneal Serous Adenocarcinoma\|Stage IIA Fallopian Tube Cancer AJCC v6 and v7\|Stage IIA Ovarian Cancer AJCC V6 and v7\|Stage IIB Fallopian Tube Cancer AJCC v6 and v7\|Stage IIB Ovarian Cancer AJCC v6 and v7\|Stage IIC Fallopian Tube Cancer AJCC v6 and v7\|Stage IIC Ovarian Cancer AJCC v6 and v7\|Stage IIIA Fallopian Tube Cancer AJCC v7\|Stage IIIA Ovarian Cancer AJCC v6 and v7\|Stage IIIA Primary Peritoneal Cancer AJCC v7\|Stage IIIB Fallopian Tube Cancer AJCC v7\|Stage IIIB Ovarian Cancer AJCC v6 and v7\|Stage IIIB Primary Peritoneal Cancer AJCC v7\|Stage IIIC Fallopian Tube Cancer AJCC v7\|Stage IIIC Ovarian Cancer AJCC v6 and v7\|Stage IIIC Primary Peritoneal Cancer AJCC v7\|Stage IV Fallopian Tube Cancer AJCC v6 and v7\|Stage IV Ovarian Cancer AJCC v6 and v7\|Stage IV Primary Peritoneal Cancer AJCC v7	October 28, 2009	Phase 1
NCT05603039	Qilu Pharmaceutical Co., Ltd.	Advanced Liver Cancer	July 1, 2021	Phase 1\|Phase 2
NCT02648711	NewLink Genetics Corporation\|Lumos Pharma	Solid Tumors	October 2015	Phase 1
NCT05180006	Gustave Roussy, Cancer Campus, Grand Paris\|Hoffmann-La Roche	Breast Cancer	February 24, 2022	Phase 2
NCT00383812	Asan Medical Center	Polypoidal Choroidal Vasculopathy	May 2006	Not Applicable
NCT00369551	National Cancer Institute (NCI)	Adenocarcinoma of the Lung\|Bronchoalveolar Cell Lung Cancer\|Large Cell Lung Cancer\|Stage II Non-small Cell Lung Cancer\|Stage IIIA Non-small Cell Lung Cancer\|Stage IIIB Non-small Cell Lung Cancer	June 2006	Phase 1
NCT03925233	Xijing Hospital	Breast Cancer Organoids	January 2, 2019
NCT01490866	SCRI Development Innovations, LLC\|Pfizer	Colorectal Cancer	January 2012	Phase 2
NCT03083990	Innovent Biologics (Suzhou) Co. Ltd.	Healthy	March 9, 2017	Phase 1
NCT05363722	Shanghai Zhongshan Hospital	Hepatocellular Carcinoma	May 2022	Phase 1
NCT04761614	Ning Jin\|Ohio State University Comprehensive Cancer Center	Metastatic Colorectal Carcinoma\|Stage IV Colorectal Cancer AJCC v8\|Stage IVA Colorectal Cancer AJCC v8\|Stage IVB Colorectal Cancer AJCC v8\|Stage IVC Colorectal Cancer AJCC v8	April 2, 2021	Phase 1
NCT00370721	Shahid Beheshti University of Medical Sciences	Diabetic Retinopathy	March 2006	Phase 3
NCT00613028	Duke University\|Genentech, Inc.	Glioblastoma\|Gliosarcoma	April 2008	Phase 2
NCT05068206	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.	Unresectable Metastatic Colorectal Cancer	October 8, 2021	Phase 2
NCT00992849	Chang Gung Memorial Hospital	Corneal Neovascularization	May 2009	Phase 2
NCT00492089	National Cancer Institute (NCI)	Adult Anaplastic Astrocytoma\|Adult Anaplastic Ependymoma\|Adult Anaplastic Meningioma\|Adult Anaplastic Oligodendroglioma\|Adult Brain Stem Glioma\|Adult Central Nervous System Germ Cell Tumor\|Adult Choroid Plexus Tumor\|Adult Diffuse Astrocytoma\|Adult Ependymoma\|Adult Grade II Meningioma\|Adult Grade III Meningioma\|Adult Malignant Hemangiopericytoma\|Adult Mixed Glioma\|Adult Oligodendroglioma\|Adult Papillary Meningioma\|Adult Pineocytoma\|Malignant Neoplasm\|Meningeal Melanocytoma\|Radiation Toxicity\|Recurrent Adenoid Cystic Carcinoma of the Oral Cavity\|Recurrent Adult Brain Tumor\|Recurrent Basal Cell Carcinoma of the Lip\|Recurrent Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity\|Recurrent Inverted Papilloma of the Paranasal Sinus and Nasal Cavity\|Recurrent Lymphoepithelioma of the Nasopharynx\|Recurrent Lymphoepithelioma of the Oropharynx\|Recurrent Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity\|Recurrent Mucoepidermoid Carcinoma of the Oral Cavity\|Recurrent Salivary Gland Cancer\|Recurrent Squamous Cell Carcinoma of the Hypopharynx\|Recurrent Squamous Cell Carcinoma of the Larynx\|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity\|Recurrent Squamous Cell Carcinoma of the Nasopharynx\|Recurrent Squamous Cell Carcinoma of the Oropharynx\|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity\|Recurrent Verrucous Carcinoma of the Larynx\|Recurrent Verrucous Carcinoma of the Oral Cavity\|Stage I Adenoid Cystic Carcinoma of the Oral Cavity\|Stage I Basal Cell Carcinoma of the Lip\|Stage I Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity\|Stage I Inverted Papilloma of the Paranasal Sinus and Nasal Cavity\|Stage I Lymphoepithelioma of the Nasopharynx\|Stage I Lymphoepithelioma of the Oropharynx\|Stage I Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity\|Stage I Mucoepidermoid Carcinoma of the Oral Cavity\|Stage I Salivary Gland Cancer\|Stage I Squamous Cell Carcinoma of the Hypopharynx\|Stage I Squamous Cell Carcinoma of the Larynx\|Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity\|Stage I Squamous Cell Carcinoma of the Nasopharynx\|Stage I Squamous Cell Carcinoma of the Oropharynx\|Stage I Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity\|Stage I Verrucous Carcinoma of the Larynx\|Stage I Verrucous Carcinoma of the Oral Cavity\|Stage III Adenoid Cystic Carcinoma of the Oral Cavity\|Stage III Basal Cell Carcinoma of the Lip\|Stage III Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity\|Stage III Inverted Papilloma of the Paranasal Sinus and Nasal Cavity\|Stage III Lymphoepithelioma of the Nasopharynx\|Stage III Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity\|Stage III Mucoepidermoid Carcinoma of the Oral Cavity\|Stage III Salivary Gland Cancer\|Stage III Squamous Cell Carcinoma of the Hypopharynx\|Stage III Squamous Cell Carcinoma of the Larynx\|Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity\|Stage III Squamous Cell Carcinoma of the Nasopharynx\|Stage III Squamous Cell Carcinoma of the Oropharynx\|Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity\|Stage III Verrucous Carcinoma of the Larynx\|Stage III Verrucous Carcinoma of the Oral Cavity\|Stage IV Adenoid Cystic Carcinoma of the Oral Cavity\|Stage IV Basal Cell Carcinoma of the Lip\|Stage IV Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity\|Stage IV Inverted Papilloma of the Paranasal Sinus and Nasal Cavity\|Stage IV Lymphoepithelioma of the Nasopharynx\|Stage IV Lymphoepithelioma of the Oropharynx\|Stage IV Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity\|Stage IV Mucoepidermoid Carcinoma of the Oral Cavity\|Stage IV Salivary Gland Cancer\|Stage IV Squamous Cell Carcinoma of the Hypopharynx\|Stage IV Squamous Cell Carcinoma of the Larynx\|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity\|Stage IV Squamous Cell Carcinoma of the Nasopharynx\|Stage IV Squamous Cell Carcinoma of the Oropharynx\|Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity\|Stage IV Verrucous Carcinoma of the Larynx\|Stage IV Verrucous Carcinoma of the Oral Cavity	June 2007	Phase 2
NCT01295112	Texas Retina Associates	Non-Ischemic Central Retinal Vein Occlusion	May 2011	Phase 2\|Phase 3
NCT05540275	Henan Provincial People´s Hospital	Recurrent Glioblastoma	November 1, 2022	Phase 2
NCT05112861	Outlook Therapeutics, Inc.	Age-Related Macular Degeneration\|Neovascular Age-related Macular Degeneration\|Wet Macular Degeneration\|BRVO - Branch Retinal Vein Occlusion\|Diabetic Macular Edema	November 15, 2021	Phase 3
NCT05488522	Abramson Cancer Center of the University of Pennsylvania	Hepatocellular Carcinoma	September 1, 2022	Phase 1
NCT01996306	Epidemiological and Clinical Research Information Network	Colorectal Neoplasms\|Neoplasm Metastasis\|Intestinal Neoplasms\|Gastrointestinal Neoplasms\|Digestive System Neoplasms	December 2, 2013	Phase 3
NCT01727089	National Cancer Institute (NCI)	Clear Cell Renal Cell Carcinoma\|Recurrent Renal Cell Carcinoma\|Stage IV Renal Cell Cancer\|Type 1 Papillary Renal Cell Carcinoma\|Type 2 Papillary Renal Cell Carcinoma	November 1, 2012	Phase 2
NCT00618657	University of California, Irvine\|National Institutes of Health (NIH)\|National Cancer Institute (NCI)	Breast Cancer\|HER2-negative Breast Cancer\|HER2-positive Breast Cancer\|Recurrent Breast Cancer\|Stage IA Breast Cancer\|Stage IB Breast Cancer\|Stage II Breast Cancer\|Stage IIIA Breast Cancer\|Stage IIIB Breast Cancer\|Stage IIIC Breast Cancer	February 2008	Phase 2
NCT00911170	Amgen	Cancer\|Colon Cancer\|Colorectal Cancer\|Fever\|Locally Advanced\|Metastatic Colorectal Cancer\|Neutropenia\|Rectal Cancer	November 3, 2009	Phase 3
NCT00737971	Rubens Belfort Jr.\|Federal University of São Paulo	Diabetic Macular Edema	August 2008	Phase 4
NCT01635790	Prof. dr. R.O. Schlingemann\|University Medical Center Groningen\|Free University Medical Center\|Erasmus Medical Center\|Radboud University Medical Center\|Leiden University Medical Center\|UMC Utrecht\|Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	Diabetic Macular Edema	June 2012	Phase 2\|Phase 3
NCT02139579	Sun Yat-sen University\|First Affiliated Hospital, Sun Yat-Sen University\|Second Affiliated Hospital, Sun Yat-Sen University	Lung, Carcinoma	May 2014	Phase 2
NCT00162669	Gustave Roussy, Cancer Campus, Grand Paris\|Hoffmann-La Roche	Hepatocellular Carcinoma	May 2005	Phase 2
NCT00700570	Hoffmann-La Roche	Colorectal Cancer	August 2008	Phase 2
NCT01187199	M.D. Anderson Cancer Center	Advanced Cancer	August 2010	Phase 1
NCT03141684	National Cancer Institute (NCI)	Metastatic Alveolar Soft Part Sarcoma\|Unresectable Alveolar Soft Part Sarcoma	March 3, 2017	Phase 2
NCT01588431	The University of Texas Health Science Center at San Antonio	Carcinoma, Squamous Cell of Head and Neck	December 2011	Phase 2
NCT01871571	University of Southern California\|National Cancer Institute (NCI)	Mucinous Adenocarcinoma of the Rectum\|Signet Ring Adenocarcinoma of the Rectum\|Stage IIA Rectal Cancer\|Stage IIB Rectal Cancer\|Stage IIC Rectal Cancer\|Stage IIIA Rectal Cancer\|Stage IIIB Rectal Cancer\|Stage IIIC Rectal Cancer	August 2, 2013	Phase 2
NCT00776698	Hoffmann-La Roche	Non-Squamous Non-Small Cell Lung Cancer	April 2009	Phase 1
NCT02093000	Hoffmann-La Roche	Lung Adenocarcinoma	November 30, 2014
NCT04158258	Hoffmann-La Roche\|Latin American Cooperative Oncology Group	Breast Cancer	February 21, 2020
NCT01695772	Hoffmann-La Roche	Colorectal Cancer	October 16, 2012	Phase 4
NCT02840409	The Hospital for Sick Children\|Hoffmann-La Roche	Low Grade Glioma	August 2016	Phase 2
NCT00992121	GlaxoSmithKline	Carcinoma, Renal Cell	November 18, 2009	Phase 1
NCT01802749	National Cancer Institute, Naples\|Mario Negri Institute for Pharmacological Research	Recurrent Ovarian Cancer	November 2013	Phase 3
NCT00976677	National Cancer Institute (NCI)	Recurrent Non-small Cell Lung Cancer\|Stage IIIB Non-small Cell Lung Cancer\|Stage IV Non-small Cell Lung Cancer	January 2010	Phase 2
NCT00887536	NSABP Foundation Inc\|Genentech, Inc.\|US Oncology Research	Breast Cancer	May 2009	Phase 3
NCT01303497	Centre Oscar Lambret\|French Sarcoma Group\|Study Group of Bone Tumors	Angiosarcoma	September 10, 2010	Phase 2
NCT01767545	Ludwig-Maximilians - University of Munich	Macular Edema Caused by Retinal Vein Occlusion	September 2010	Phase 4
NCT00524069	Roswell Park Cancer Institute\|National Cancer Institute (NCI)	Pancreatic Cancer	January 2007	Not Applicable
NCT03414983	Bristol-Myers Squibb\|Ono Pharmaceutical Co. Ltd	Colorectal Cancer	February 20, 2018	Phase 2\|Phase 3
NCT00499369	National Cancer Institute (NCI)\|North Central Cancer Treatment Group\|Cancer and Leukemia Group B\|Eastern Cooperative Oncology Group\|NCIC Clinical Trials Group	Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer	June 2007	Phase 3
NCT03425292	Saint John´s Cancer Institute	Newly Diagnosed High Grade Glioma	March 1, 2018	Phase 1
NCT00276055	New Mexico Cancer Care Alliance	Sarcoma	November 2005	Phase 1
NCT00681876	Hellenic Oncology Research Group\|University Hospital of Crete	Colorectal Cancer	April 2008	Phase 2
NCT04275414	Qilu Hospital of Shandong University\|Renmin Hospital of Wuhan University\|Moriggia-Pelascini Gravedona Hospital	Coronavirus Infections	February 15, 2020	Phase 2
NCT02226289	Sixth Affiliated Hospital, Sun Yat-sen University	Neoplasm\|Colorectal Cancer\|Metastatic Neoplasm	September 2020	Phase 2
NCT04721132	M.D. Anderson Cancer Center	Resectable Hepatocellular Carcinoma\|Stage I Hepatocellular Carcinoma AJCC v8\|Stage IA Hepatocellular Carcinoma AJCC v8\|Stage IB Hepatocellular Carcinoma AJCC v8\|Stage II Hepatocellular Carcinoma AJCC v8	February 10, 2021	Phase 2
NCT01399190	Hoffmann-La Roche	Colorectal Cancer	July 2011
NCT01967810	Angiochem Inc	Glioma\|Glioblastoma\|Brain Tumor, Recurrent	October 2013	Phase 2
NCT00809133	Boehringer Ingelheim	Neoplasms	May 2007	Phase 1
NCT00720512	Gruppo Oncologico del Nord-Ovest	Colorectal Cancer	June 2008	Phase 3
NCT00417833	Asociación para Evitar la Ceguera en México	Diabetic Proliferative Retinopathy\|Vascular Vein Oclussion\|Choroidal Neovascularization	December 2005	Phase 2\|Phase 3
NCT03462251	iOMEDICO AG\|Novartis Pharmaceuticals	Breast Cancer\|Hormone Receptor Positive Tumor\|HER 2 Negative Breast Cancer	May 24, 2018	Phase 3
NCT02015351	University of Sao Paulo\|Fundação de Amparo à Pesquisa do Estado de São Paulo	Choroidal Neovascularization	September 2012	Not Applicable
NCT01459380	National Cancer Institute (NCI)\|NRG Oncology	Ovarian Clear Cell Cystadenocarcinoma\|Ovarian Endometrioid Adenocarcinoma\|Ovarian Seromucinous Carcinoma\|Ovarian Serous Cystadenocarcinoma\|Recurrent Fallopian Tube Carcinoma\|Recurrent Ovarian Carcinoma\|Recurrent Primary Peritoneal Carcinoma\|Undifferentiated Ovarian Carcinoma	October 11, 2011	Phase 1
NCT01996826	Reza Dana, MD\|United States Department of Defense\|Bascom Palmer Eye Institute\|New York Presbyterian Hospital\|Massachusetts Eye and Ear Infirmary	Corneal Neovascularization\|Corneal Graft Failure	April 2014	Phase 1\|Phase 2
NCT01072357	Reza Dana, MD\|Massachusetts Eye and Ear Infirmary	Corneal Neovascularization\|Corneal Graft Failure	December 2009	Phase 1\|Phase 2
NCT00378573	Sanofi	Non-small Cell Lung Cancer	January 2007	Phase 2
NCT00559754	Hoffmann-La Roche	Breast Cancer	December 2007	Phase 2
NCT01648348	National Cancer Institute (NCI)	Adult Anaplastic Astrocytoma\|Adult Anaplastic Oligodendroglioma\|Adult Giant Cell Glioblastoma\|Adult Glioblastoma\|Adult Gliosarcoma\|Adult Mixed Glioma\|Recurrent Adult Brain Neoplasm	November 2012	Phase 1\|Phase 2
NCT00101686	Pfizer	Colorectal Neoplasms	February 2003	Phase 3
NCT05546879	University Hospital, Grenoble\|NETRIS Pharma	Hepatocellular Carcinoma	November 2022	Phase 1
NCT03451370	Istituto Oncologico Veneto IRCCS	Elderly Metastatic Colorectal Cancer Patients	November 1, 2017
NCT00874744	Universidade Federal de Goias	Diabetic Macular Edema	March 2008	Phase 2
NCT00290810	National Cancer Institute (NCI)	B-cell Chronic Lymphocytic Leukemia\|Refractory Chronic Lymphocytic Leukemia	December 2005	Phase 2
NCT01229943	National Cancer Institute (NCI)	Advanced Pancreatic Neuroendocrine Tumor\|Locally Advanced Pancreatic Neuroendocrine Tumor\|Pancreatic Gastrinoma\|Pancreatic Neuroendocrine Tumor G1\|Pancreatic Neuroendocrine Tumor G2\|Pancreatic Vipoma	October 15, 2010	Phase 2
NCT00411593	M.D. Anderson Cancer Center\|Millennium Pharmaceuticals, Inc.\|Genentech, Inc.	Lung Cancer	November 2006	Phase 1\|Phase 2
NCT00892710	SCRI Development Innovations, LLC\|Genentech, Inc.	Non Small Cell Lung Cancer	June 2009	Phase 2
NCT05263947	Tianjin Medical University Cancer Institute and Hospital	Carcinoma, Non-Small-Cell Lung\|Bevacizumab\|EGF-R Positive Non-Small Cell Lung Cancer\|Tyrosine Kinase Inhibitor	August 30, 2021	Phase 3
NCT05035381	Tianjin Medical University Cancer Institute and Hospital	MSI-H Advanced Colorectal Cancer	January 1, 2019	Phase 2
NCT05582577	Shahid Beheshti University of Medical Sciences	Diabetic Macular Edema	October 15, 2022	Phase 2\|Phase 3
NCT00121199	National Cancer Institute (NCI)	Contiguous Stage II Adult Diffuse Large Cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma\|Stage III Adult Diffuse Large Cell Lymphoma\|Stage IV Adult Diffuse Large Cell Lymphoma	June 2005	Phase 2
NCT05314673	University Hospital Fattouma Bourguiba	Pterygium	January 1, 2019	Phase 4
NCT00819780	Amgen	Colon Cancer\|Colorectal Cancer\|Rectal Cancer\|Metastatic Colorectal Cancer	April 24, 2009	Phase 2
NCT03698461	Asan Medical Center\|Hoffmann-La Roche	Colorectal Neoplasms\|Neoplasm Metastasis\|Colonic Neoplasms\|Rectal Neoplasms	May 15, 2019	Phase 2
NCT00600262	Asociación para Evitar la Ceguera en México	Severe Nonproliferative\|Proliferative Diabetic Retinopathy\|Active Photocoagulated Diabetic Retinopathy	December 2005	Phase 2\|Phase 3
NCT00717990	University Hospital of Crete	Metastatic Colorectal Cancer	April 2008	Phase 2
NCT00369070	Amgen	Advanced Non-squamous NSCLC	January 31, 2007	Phase 2
NCT03834753	Outlook Therapeutics, Inc.	Age-related Macular Degeneration\|Neovascular Age-related Macular Degeneration\|Wet Macular Degeneration	June 25, 2019	Phase 3
NCT04730999	Gruppo Oncologico Italiano di Ricerca Clinica\|Roche Pharma, Italy\|YGHEA, CRO Division of Ecol Studio spa\|Dr. Luca Boni U.O. Epidemiologia Clinica, IRCCS Ospedale Policlinico San Martino - IST NORD CBA	Small Cell Lung Cancer	July 1, 2020	Phase 2
NCT00729846	California Retina Consultants\|Novartis	Age Related Macular Degeneration\|Choroidal Neovascularization\|Macular Edema	May 2006	Phase 2
NCT01236560	National Cancer Institute (NCI)	Brain Stem Glioma\|Cerebral Astrocytoma\|Childhood Cerebellar Anaplastic Astrocytoma\|Childhood Cerebral Anaplastic Astrocytoma\|Childhood Spinal Cord Neoplasm	November 15, 2010	Phase 2\|Phase 3
NCT01837251	AGO Research GmbH\|Arbeitsgemeinschaft Gynaekologische Onkologie Austria\|ARCAGY+ GINECO GROUP\|Australia New Zealand Gynaecological Oncology Group\|Scottish Gynaecological Cancer Study Group	Recurrent Platinum-sensitive Ovarian Cancer	May 2013	Phase 3
NCT01293942	Ottawa Hospital Research Institute\|Hoffmann-La Roche\|Sanofi	Metastatic Colorectal Cancer	March 2011	Phase 2
NCT04245085	ETOP IBCSG Partners Foundation\|Roche Pharma AG	EGFRmutant Stage IIIB+C or IV Non-squamous NSCLC	September 29, 2020	Phase 2
NCT03654833	University of Leicester\|British Lung Foundation\|Clovis Oncology, Inc.\|Eli Lilly and Company\|Merck Sharp & Dohme LLC\|BerGenBio ASA\|Roche Pharma AG\|University Hospitals, Leicester\|The Christie NHS Foundation Trust\|GlaxoSmithKline	Mesothelioma, Malignant	January 28, 2019	Phase 2
NCT00296062	Case Comprehensive Cancer Center\|National Cancer Institute (NCI)	Colorectal Cancer\|Unspecified Adult Solid Tumor, Protocol Specific	March 2006	Phase 1
NCT02857920	Fuda Cancer Hospital, Guangzhou\|Shenzhen Hank Bioengineering Institute	Malignant Solid Tumour	August 1, 2016	Phase 1\|Phase 2
NCT01836536	Center Eugene Marquis	Glioblastoma\|Glioma	September 2012	Not Applicable
NCT03161041	Hospices Civils de Lyon	Colorectal Carcinomatosis	September 21, 2018	Phase 2
NCT00114179	National Cancer Institute (NCI)\|NRG Oncology	Adenocarcinoma of the Pancreas\|Stage II Pancreatic Cancer\|Stage III Pancreatic Cancer	January 2005	Phase 2
NCT00548197	Iran University of Medical Sciences	Intravitreal Bevacizumab Injection\|Pars Plana Vitrectomy\|Tractional Retinal Detachment\|Diabetic Retinopathy	February 2007	Phase 1
NCT01686529	Instituto de Oftalmología Fundación Conde de Valenciana	Pterygium	March 2010	Phase 1
NCT00625651	Amgen	Metastatic Colorectal Cancer\|Colon Cancer\|Colorectal Cancer\|Rectal Cancer	October 2007	Phase 1\|Phase 2
NCT04138420	Federico II University	Exudative Age-related Macular Degeneration	January 25, 2017
NCT00727753	University of Zurich	Macular Degeneration	July 2008
NCT00804921	University of Sao Paulo	Macular Edema\|Diabetic Retinopathy\|Macular Degeneration		Phase 2
NCT01724385	Khon Kaen University	Vitreous Hemorrhage\|Proliferative Diabetic Retinopathy	August 2012	Phase 4
NCT04164069	Anne Noonan\|Ohio State University Comprehensive Cancer Center	Advanced Colorectal Carcinoma\|Metastatic Colorectal Carcinoma\|Stage IV Colorectal Cancer AJCC v8\|Stage IVA Colorectal Cancer AJCC v8\|Stage IVB Colorectal Cancer AJCC v8\|Stage IVC Colorectal Cancer AJCC v8\|Stage II Colon Cancer\|Stage II Rectal Cancer\|Stage III Colon Cancer\|Stage III Rectal Cancer\|Esophageal Cancer\|Pancreatic Cancer\|Bile Duct Cancer\|Gastric Cancer\|Gall Bladder Cancer\|Small Bowel Adenocarcinoma	September 2, 2020	Phase 1
NCT01051934	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Non-Small Cell Lung Cancer\|Adenocarcinoma	December 29, 2009	Phase 1
NCT02641873	Sumitomo Pharma Co., Ltd.	Metastatic Colorectal Cancer	December 2015	Phase 1
NCT00541099	Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Lung Cancer	January 2008	Phase 2
NCT03732235	Giammaria Fiorentini\|International Group of Endovascular Oncology	Liver Metastasis Colon Cancer	October 1, 2018
NCT03616691	Samsung Medical Center	Non Small Cell Lung Cancer	August 1, 2018	Phase 2
NCT04194203	Hoffmann-La Roche	Carcinoma, Non-Small-Cell Lung	April 9, 2020	Phase 3
NCT00574769	University of Southern California\|Novartis\|Genentech, Inc.	Prostate Cancer	February 17, 2010	Phase 1\|Phase 2
NCT00350753	Rigshospitalet, Denmark\|Aarhus University Hospital	Cholangiocarcinoma\|Gallbladder Cancer	June 2006	Phase 2
NCT00426998	Retinal Consultants Medical Group	Choroidal Neovascularization\|Macular Degeneration	April 2006	Phase 2
NCT01290263	Dana-Farber Cancer Institute\|Amgen	Glioblastoma Multiforme	December 2010	Phase 1\|Phase 2
NCT00611793	SCRI Development Innovations, LLC\|Novartis	Refractory Malignancy\|Advanced Malignancies	October 2004	Phase 1
NCT04101877	Vastra Gotaland Region	Neovascular Age-related Macular Degeneration	September 3, 2020	Phase 2
NCT01507480	Hospices Civils de Lyon	Rendu Osler Disease\|Telangiectasia, Hereditary Hemorrhagic	October 2011	Phase 1
NCT03115762	Jiangsu Aosaikang Pharmaceutical Co., Ltd.	Healthy	June 2017	Phase 1
NCT01656304	Barbara Ann Karmanos Cancer Institute\|Genentech, Inc.	Adenocarcinoma of the Prostate\|Recurrent Prostate Cancer\|Stage I Prostate Cancer\|Stage IIA Prostate Cancer\|Stage IIB Prostate Cancer\|Stage III Prostate Cancer	May 2007	Phase 2
NCT02847559	Northwestern University\|NovoCure Ltd.\|National Cancer Institute (NCI)	Anaplastic (Malignant) Meningioma\|Atypical Meningioma\|Grade II Meningioma\|Grade III Meningioma\|Recurrent Meningioma\|Supratentorial Meningioma	August 2016	Phase 2
NCT04181060	National Cancer Institute (NCI)	Advanced Lung Non-Squamous Non-Small Cell Carcinoma\|Metastatic Lung Non-Squamous Non-Small Cell Carcinoma\|Recurrent Lung Non-Squamous Non-Small Cell Carcinoma\|Stage IIIB Lung Cancer AJCC v8\|Stage IV Lung Cancer AJCC v8\|Stage IVA Lung Cancer AJCC v8\|Stage IVB Lung Cancer AJCC v8	October 22, 2020	Phase 3
NCT00499694	Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Prostate Cancer	October 2007	Not Applicable
NCT01069796	ARCAGY+ GINECO GROUP	Triple Negative Metastatic Breast Cancer	April 2010	Phase 2
NCT01200121	AIO-Studien-gGmbH	Malignant Ascites\|Gastrointestinal Cancers	February 2010	Phase 2
NCT02339116	Gruppo Oncologico del Nord-Ovest	Metastatic Colorectal Cancer	February 26, 2015	Phase 3
NCT02416999	Hebei Yanda Hospital\|Beijing Tiantan Hospital	Recurrent High-grade Glioma	May 2015	Not Applicable
NCT04109924	Roswell Park Cancer Institute\|National Comprehensive Cancer Network	Advanced Colorectal Carcinoma\|Metastatic Colon Adenocarcinoma\|Metastatic Rectal Adenocarcinoma\|Recurrent Colon Adenocarcinoma\|Recurrent Colorectal Adenocarcinoma\|Recurrent Rectal Adenocarcinoma\|Stage III Colon Cancer AJCC v8\|Stage III Colorectal Cancer AJCC v8\|Stage III Rectal Cancer AJCC v8\|Stage IIIA Colon Cancer AJCC v8\|Stage IIIA Colorectal Cancer AJCC v8\|Stage IIIB Colorectal Cancer AJCC v8\|Stage IIIB Rectal Cancer AJCC v8\|Stage IIIC Colon Cancer AJCC v8\|Stage IIIC Colorectal Cancer AJCC v8\|Stage IV Colon Cancer AJCC v8\|Stage IVA Colorectal Cancer AJCC v8\|Stage IVA Rectal Cancer AJCC v8\|Stage IVB Colon Cancer AJCC v8\|Stage IVB Colorectal Cancer AJCC v8\|Stage IVB Rectal Cancer AJCC v8\|Stage IVC Colon Cancer AJCC v8\|Stage IVC Colorectal Cancer AJCC v8\|Stage IVC Rectal Cancer AJCC v8\|Unresectable Colon Adenocarcinoma\|Unresectable Colorectal Carcinoma\|Unresectable Rectal Adenocarcinoma	December 27, 2019	Phase 2
NCT01024504	Hellenic Oncology Research Group\|University Hospital of Crete	Metastatic Colorectal Cancer	March 2006	Phase 2
NCT00753909	Hellenic Oncology Research Group	Non Small Cell Lung Cancer	November 2008	Phase 2
NCT00203411	Translational Oncology Research International\|Genentech, Inc.	Colorectal Cancer	March 2006	Phase 2
NCT00392704	SCRI Development Innovations, LLC\|Genentech, Inc.	Head and Neck Cancer	December 2006	Phase 2
NCT00442507	Washington University School of Medicine	Esophageal Neoplasms\|Esophageal Diseases	March 2007	Phase 2
NCT00393861	Indiana University\|Genentech, Inc.	Neoplasms, Germ Cell and Embryonal	October 2006	Phase 2
NCT04832776	Fudan University	Liver Metastasis Colon Cancer	April 17, 2021	Phase 2
NCT01214720	Hoffmann-La Roche	Pancreatic Cancer	July 2005	Phase 3
NCT03607643	Leaf Vertical Inc.	Cancer of Pancreas\|Cancer of Liver\|Cancer of Rectum\|Cancer of Colon\|Cancer, Gall Bladder\|Myeloma Multiple\|Glioblastoma Multiforme	January 15, 2019	Phase 1\|Phase 2
NCT00288015	Northwestern University\|Genentech, Inc.	Sarcoma	October 2005	Phase 2
NCT00403130	George Albert Fisher\|Genentech, Inc.\|Eli Lilly and Company\|Stanford University	Breast Cancer\|Metastatic Breast Cancer	February 2006	Phase 2
NCT04067856	Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center\|Allergan\|Doheny Image Reading Center	Diabetic Macular Edema\|Cataract	January 1, 2020	Not Applicable
NCT00467012	Chugai Pharmaceutical	Metastatic Breast Cancer	April 2007	Phase 2
NCT00281528	Celgene	Breast Neoplasms\|Neoplasm Metastasis	February 1, 2006	Phase 2
NCT01202032	Centre Leon Berard	Metastatic Renal Cell Carcinoma\|Advanced Refractory Solid Tumors Histologically or Cytologically Confirmed	July 2010	Phase 1
NCT01442649	UNICANCER	Colorectal Cancer	December 2010	Phase 2
NCT01243359	National Cancer Institute (NCI)	Clear Cell Renal Cell Carcinoma\|Recurrent Renal Cell Cancer\|Stage I Renal Cell Cancer\|Stage II Renal Cell Cancer\|Stage III Renal Cell Cancer\|Stage IV Renal Cell Cancer\|Unspecified Adult Solid Tumor, Protocol Specific	October 2010	Phase 1
NCT03961698	Infinity Pharmaceuticals, Inc.\|Roche Pharma AG	Breast Cancer\|Renal Cell Carcinoma	December 17, 2019	Phase 2
NCT00388700	Galectin Therapeutics Inc.	Colorectal Cancer	October 2006	Phase 2
NCT00588237	Memorial Sloan Kettering Cancer Center\|Genentech, Inc.	Ovarian Cancer\|Primary PERITONEUM\|Fallopian Tube Cancer	August 2006	Phase 2
NCT04725448	Sichuan Cancer Hospital and Research Institute	Pulmonary Sarcomatoid Carcinoma\|Non-small Cell Lung Cancer\|Lung Diseases\|Thoracic Neoplasms	April 6, 2021	Phase 2
NCT01623102	Sichuan Cancer Hospital and Research Institute	Lung Cancer	February 2013	Phase 2
NCT01441388	Pfizer	Carcinoma, Renal Cell\|Glioblastoma\|Carcinoma, Hepatocellular	December 2011	Phase 1
NCT02394834	Takeda	Colorectal Cancer	May 29, 2015	Phase 3
NCT00403026	Narayana Nethralaya	Wet AMD\|Macular Oedema\|Proliferative Diabetic Retinopathy	August 2006	Not Applicable
NCT00524875	Shahid Beheshti University of Medical Sciences	Diabetic Retinopathy	January 2007	Not Applicable
NCT05480306	Leap Therapeutics, Inc.	Colorectal Cancer\|Colorectal Adenocarcinoma\|Colo-rectal Cancer\|Colorectal Cancer Metastatic	August 30, 2022	Phase 2
NCT00052390	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Sarcoma	October 2002	Phase 2
NCT00352521	Duke University\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors	April 2006	Phase 2
NCT01048554	Mt. Sinai Medical Center, Miami\|Northern California Melanoma Center	Melanoma	November 2009	Phase 2
NCT01256762	Geron Corporation	Locally Recurrent or Metastatic Breast Cancer	November 2010	Phase 2
NCT05530785	Yongchang Zhang\|Hunan Province Tumor Hospital	Hepatocellular Carcinoma Non-resectable	August 1, 2022	Not Applicable
NCT00755157	University Hospital of Crete	Small Cell Lung Cancer	April 2008	Phase 2
NCT00754650	Hoffmann-La Roche	Lymphocytic Leukemia, Chronic	September 2008	Phase 2
NCT03387085	ImmunityBio, Inc.	Triple Negative Breast Cancer	March 16, 2018	Phase 1\|Phase 2
NCT00049088	National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	August 2002	Phase 1
NCT05113511	First Affiliated Hospital of Zhejiang University\|Sinocelltech Ltd.	Healthy	May 9, 2018	Phase 1
NCT00451906	Hoffmann-La Roche	Non-Squamous Non-Small Cell Lung Cancer	August 2006	Phase 4
NCT00107315	Roswell Park Cancer Institute	Colorectal Cancer	July 2004	Phase 2
NCT00909987	Grupo Espanol Multidisciplinario del Cancer Digestivo\|Royal Marsden NHS Foundation Trust	Rectum Cancer	March 2009	Phase 2
NCT00074308	National Cancer Institute (NCI)	Recurrent Melanoma\|Stage III Melanoma\|Stage IV Melanoma\|Unspecified Adult Solid Tumor, Protocol Specific	October 2003	Phase 1\|Phase 2
NCT04556071	Xiaoxiang Chen\|Jiangsu Cancer Institute & Hospital	Ovarian Neoplasms\|Fallopian Tube Neoplasms\|Endocrine Gland Neoplasms\|Neoplasms by Site\|Neoplasms\|Genital Neoplasms, Female\|Urogenital Neoplasms\|Neoplasms, Glandular and Epithelial\|Neoplasms by Histologic Type\|Carcinoma, Ovarian Epithelial\|Ovarian Diseases\|Adnexal Diseases\|Genital Diseases, Female\|Endocrine System Diseases\|Gonadal Disorders\|Carcinoma\|Bevacizumab\|Enzyme Inhibitors\|Antineoplastic Agents\|Molecular Mechanisms of Pharmacological Action\|Angiogenesis\|BRCA1 Mutation\|BRCA2 Mutation\|Homologous Recombination Deficiency	November 6, 2020	Phase 2
NCT00843440	Hospices Civils de Lyon	Hemorrhagic Hereditary Telangiectasia	March 2009	Phase 2
NCT04107168	CCTU- Cancer Theme\|Microbiotica Ltd\|Cambridge University Hospitals NHS Foundation Trust	Melanoma\|Renal Cancer\|Lung Cancer	July 8, 2020
NCT00781846	Merck Sharp & Dohme LLC\|Ariad Pharmaceuticals	Solid Tumor	October 2008	Phase 1
NCT02521051	Massachusetts General Hospital\|Genentech, Inc.	Non-Small Cell Lung Cancer (NSCLC)	October 2015	Phase 1\|Phase 2
NCT00667277	Ronald Hoffman\|Myeloproliferative Disorders-Research Consortium\|National Cancer Institute (NCI)\|Icahn School of Medicine at Mount Sinai	Myelofibrosis	March 2008	Phase 2
NCT03181100	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Metastatic Thyroid Gland Carcinoma\|Poorly Differentiated Thyroid Gland Carcinoma\|Stage IVA Thyroid Gland Anaplastic Carcinoma AJCC v8\|Stage IVB Thyroid Gland Anaplastic Carcinoma AJCC v8\|Stage IVC Thyroid Gland Anaplastic Carcinoma AJCC v8\|Thyroid Gland Anaplastic Carcinoma\|Unresectable Thyroid Gland Carcinoma	July 27, 2017	Phase 2
NCT00804206	Asociación para Evitar la Ceguera en México	Macular Edema	July 2008	Phase 4
NCT01013285	Jonsson Comprehensive Cancer Center	Brain and Central Nervous System Tumors	June 2006	Phase 2
NCT02036424	Raj K. Maturi, MD\|Allergan\|Maturi, Raj K., M.D., P.C.	Diabetic Macular Edema	January 2014	Phase 4
NCT01288404	Ramathibodi Hospital	Pterygium of the Conjunctiva and Cornea	January 2008	Not Applicable
NCT01012297	National Cancer Institute (NCI)\|NRG Oncology	Recurrent Uterine Corpus Sarcoma\|Stage IIIA Uterine Sarcoma\|Stage IIIB Uterine Sarcoma\|Stage IIIC Uterine Sarcoma\|Stage IVA Uterine Sarcoma\|Stage IVB Uterine Sarcoma\|Uterine Corpus Leiomyosarcoma	November 2009	Phase 3
NCT01113398	Katy Peters\|Amgen\|Duke University	Glioblastoma Multiforme\|Gliosarcoma	August 2010	Phase 2
NCT00807573	Memorial Sloan Kettering Cancer Center	Lung Cancer	December 2008	Phase 2
NCT01878422	Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori	Metastatic Colorectal Cancer	November 2007	Phase 3
NCT00116506	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital\|Beth Israel Deaconess Medical Center\|Genentech, Inc.\|Sanofi-Synthelabo	Colorectal Cancer\|Neoplasm Metastasis	January 2005	Phase 2
NCT01635803	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)\|Leiden University Medical Center\|Free University Medical Center\|Erasmus Medical Center\|Radboud University Medical Center\|UMC Utrecht\|University Medical Center Groningen	Retinal Vein Occlusion	June 2012	Phase 2\|Phase 3
NCT01390948	Hoffmann-La Roche	High Grade Glioma	October 18, 2011	Phase 2
NCT01022541	Royal Marsden NHS Foundation Trust\|Roche Pharma AG	Metastatic Colorectal Cancer	June 2006	Phase 2
NCT00755118	University Hospital of Crete	Colorectal Cancer	October 2008	Phase 2
NCT04619303	Lions Eye Institute, Perth, Western Australia\|Lions Outback Vision\|Allergan	Diabetic Macular Edema\|Diabetic Retinopathy	February 7, 2017	Phase 4
NCT02555800	Centro de Investigación en. Enfermedades Infecciosas, Mexico	Recurrent Respiratory Papillomatosis	December 2014	Phase 2
NCT01834014	EPS Corporation	Liver Metastasis\|Colorectal Cancer	May 2013	Not Applicable
NCT00959647	Genentech, Inc.	Ovarian Cancer\|Basal Cell Carcinoma\|Metastatic Colorectal Cancer	September 2009	Phase 2
NCT02217956	Gustave Roussy, Cancer Campus, Grand Paris	Ovarian Adenocarcinoma\|Fallopian Tube Adenocarcinoma\|Primary Peritoneal Carcinoma	June 2011	Phase 1
NCT04605796	Shanghai Junshi Bioscience Co., Ltd.	Advanced Hepatocellular Carcinoma (HCC)	April 10, 2020	Phase 2
NCT00321685	National Cancer Institute (NCI)	Rectal Adenocarcinoma\|Stage II Rectal Cancer AJCC v7\|Stage III Rectal Cancer AJCC v7	July 25, 2006	Phase 2
NCT03912415	Biocad	Cervical Cancer	October 1, 2019	Phase 3
NCT02681549	Yale University	Melanoma\|Non-small Cell Lung Cancer\|Brain Metastasis	May 2016	Phase 2
NCT00462423	Lynn E. Spitler, MD\|Celgene Corporation\|Genentech, Inc.\|Northern California Melanoma Center	Metastatic Malignant Melanoma	April 2007	Phase 2
NCT00533429	Eli Lilly and Company\|Genentech, Inc.	Non-small Cell Lung Cancer	October 2007	Phase 2
NCT01478321	Northwestern University	Adult Anaplastic Astrocytoma\|Adult Anaplastic Ependymoma\|Adult Anaplastic Oligodendroglioma\|Adult Giant Cell Glioblastoma\|Adult Glioblastoma	December 14, 2011	Phase 2
NCT02005549	Hoffmann-La Roche	Breast Cancer	February 2006	Phase 2
NCT00354978	M.D. Anderson Cancer Center\|Genentech, Inc.\|Pfizer	Colorectal Cancer	January 2005	Phase 2
NCT00591734	SCRI Development Innovations, LLC\|Genentech, Inc.\|Novartis	Metastatic Melanoma	January 2008	Phase 2
NCT01349660	SCRI Development Innovations, LLC\|Novartis	Glioblastoma Multiforme	December 2011	Phase 1\|Phase 2
NCT00354679	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Esophageal Cancer	April 2006	Phase 2
NCT00436332	Southwest Oncology Group\|National Cancer Institute (NCI)	Lung Cancer	July 2007	Phase 2
NCT01182350	Karen D. Wright MD\|Boston Children´s Hospital\|University of California, San Francisco\|Ann & Robert H Lurie Children´s Hospital of Chicago\|Children´s Healthcare of Atlanta\|Children´s Hospital Colorado\|Children´s Hospital Los Angeles\|Children´s Hospital of Michigan\|Children´s Hospitals and Clinics of Minnesota\|Cook Children´s Medical Center\|OHSU Doernbecher Children´s Hospital\|Duke University\|Johns Hopkins University\|Nicklaus Children´s Hospital f+k+a Miami Children´s Hospital\|Nemours Children´s Clinic\|New York University\|Milton S. Hershey Medical Center\|Seattle Children´s Hospital\|Lucile Packard Children´s Hospital\|University of Louisville\|Children´s National Research Institute\|Washington University School of Medicine\|Phoenix Children´s Hospital\|Medical University of South Carolina\|Dana-Farber Cancer Institute	Diffuse Intrinsic Pontine Glioma	September 2011	Phase 2
NCT04175158	Genor Biopharma Co., Ltd.	Non-small Cell Lung Cancer	April 24, 2017	Phase 1
NCT03169777	ImmunityBio, Inc.	Colorectal Cancer	August 2018	Phase 1\|Phase 2
NCT00800202	Hoffmann-La Roche	Non-Small Cell Lung Cancer	April 2009	Phase 2
NCT00567554	German Breast Group\|AGO Study Group	Breast Cancer	October 2007	Phase 3
NCT01359397	The Netherlands Cancer Institute	Metastatic Gastric Cancer\|Adenocarcinoma of the Gastro-oesophageal Junction	March 2011	Phase 2
NCT01197170	M.D. Anderson Cancer Center	Solid Tumors\|Advanced Cancer	September 7, 2010	Phase 1
NCT00974389	Osaka Medical College\|National Cancer Institute (NCI)	Colorectal Cancer	July 2009	Phase 2
NCT00980239	M.D. Anderson Cancer Center	Liver Cancer\|Advanced Cancer	September 2009	Phase 1
NCT01428388	Barnes Retina Institute\|Retina Associates of Florida, P.A.\|Illinois Retina Associates\|Kresge Eye Institute\|Long Island Vitreoretinal Consultants\|Mid Atlantic Retina\|Retina Associates, Kansas City\|Massachusetts Eye and Ear Infirmary	Retinal Vein Occlusion\|Macular Edema	September 2011	Not Applicable
NCT00536640	Aktion Bronchialkarzinom e.V.\|Roche Pharma AG	Carcinoma, Non-Small-Cell Lung	November 2007	Phase 2
NCT02060305	National Taiwan University Hospital	Hemophilia\|Synovitis	February 1, 2014	Phase 1
NCT01501760	University Hospital, Limoges	Corneal Newvessels	May 13, 2012	Phase 3
NCT03635489	Hoffmann-La Roche	Ovarian Cancer\|Fallopian Tube Cancer\|Primary Peritoneal Cancer	August 15, 2018	Phase 3
NCT00361231	Massachusetts General Hospital\|Genentech, Inc.\|Sanofi\|Beth Israel Deaconess Medical Center\|Brigham and Women´s Hospital\|Dana-Farber Cancer Institute	Biliary Tract Cancer\|Gallbladder Adenocarcinoma	May 2006	Phase 2
NCT01213238	M.D. Anderson Cancer Center	Advanced Cancers	September 30, 2010	Phase 1
NCT05030493	Takeda	Colorectal Cancer	August 31, 2021
NCT01095809	Hospital Clinic of Barcelona	Uveitis	April 2010	Phase 3
NCT05355155	The First Affiliated Hospital with Nanjing Medical University	Post-orthotopic Liver Transplantation\|Hepatocellular Carcinoma Recurrent	May 1, 2022	Phase 2
NCT00569790	Taiho Pharmaceutical Co., Ltd.	Colorectal Cancer	October 2007	Phase 2
NCT05609370	BeiGene	Unresectable or Metastatic Microsatellite Stable+Mismatch Repair Proficient Colorectal Cancer	November 2022	Phase 1\|Phase 2
NCT00900172	ECOG-ACRIN Cancer Research Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Lung Cancer	March 15, 2008
NCT01652560	LiNanlin,Ph.D, Chief Physician,Clinical Professor\|Roche Pharma AG\|Xijing Hospital	Breast Cancer\|Bevacizumab\|Neoadjuvant Chemotherapy\|Molecular Targeted Therapy	June 2012
NCT01910610	GERCOR - Multidisciplinary Oncology Cooperative Group\|Hoffmann-La Roche	Colorectal Cancer Metastatic	October 30, 2013	Phase 3
NCT04126044	Pfizer	Pharmacokinetics	January 22, 2021	Phase 1
NCT03661723	Dana-Farber Cancer Institute\|Merck Sharp & Dohme LLC	Glioblastoma	September 28, 2018	Phase 2
NCT01159236	M.D. Anderson Cancer Center	Breast Cancer	September 2010	Not Applicable
NCT03227263	Hospices Civils de Lyon	Rendu Osler Disease\|Telangiectasia, Hereditary Hemorrhagic	September 28, 2017	Phase 3
NCT04224636	Ludwig-Maximilians - University of Munich	Hepatocellular Carcinoma Non-resectable	April 6, 2020	Phase 2
NCT03351296	Gustave Roussy, Cancer Campus, Grand Paris\|National Cancer Institute, France	Pancreatic Cancer	February 9, 2018	Phase 2
NCT00886691	GOG Foundation\|National Cancer Institute (NCI)	Recurrent Fallopian Tube Carcinoma\|Recurrent Ovarian Carcinoma\|Recurrent Primary Peritoneal Carcinoma	December 27, 2010	Phase 2
NCT03743662	Memorial Sloan Kettering Cancer Center	Glioblastoma	November 12, 2018	Phase 2
NCT02768389	Case Comprehensive Cancer Center\|University of Cincinnati\|OhioHealth Research Institute	Glioblastoma\|Brain Tumor	September 6, 2016	Early Phase 1
NCT05238831	OHSU Knight Cancer Institute\|Oregon Health and Science University\|Genentech, Inc.	Anatomic Stage III Breast Cancer AJCC v8\|Anatomic Stage IV Breast Cancer AJCC v8\|Locally Advanced Breast Carcinoma\|Locally Advanced Malignant Solid Neoplasm\|Locally Advanced Ovarian Carcinoma\|Metastatic Breast Carcinoma\|Metastatic Malignant Solid Neoplasm\|Metastatic Ovarian Carcinoma\|Refractory Breast Carcinoma\|Refractory Malignant Solid Neoplasm\|Refractory Ovarian Carcinoma\|Stage III Ovarian Cancer AJCC v8\|Stage IV Ovarian Cancer AJCC v8\|Unresectable Malignant Solid Neoplasm\|Unresectable Ovarian Carcinoma	December 1, 2022	Phase 2
NCT01159171	Hoffmann-La Roche	Colorectal Cancer	January 2006	Phase 2
NCT01627249	Jaeb Center for Health Research\|National Eye Institute (NEI)\|Genentech, Inc.\|Regeneron Pharmaceuticals	Diabetic Macular Edema	August 2012	Phase 3
NCT01621880	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Nasopharyngeal Carcinoma\|Adverse Effect of Radiation Therapy\|Brain Necrosis	June 2012	Phase 2
NCT00891527	Boston Children´s Hospital	Pulmonary Veno Occlusive Disease	October 2008	Phase 1\|Phase 2
NCT00600301	Asociación para Evitar la Ceguera en México	Diffuse Diabetic Macular Edema		Phase 3
NCT00262067	Genentech, Inc.	Metastatic Breast Cancer	December 2005	Phase 3
NCT00055913	National Cancer Institute (NCI)	Recurrent Squamous Cell Carcinoma of the Hypopharynx\|Recurrent Squamous Cell Carcinoma of the Larynx\|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity\|Recurrent Squamous Cell Carcinoma of the Nasopharynx\|Recurrent Squamous Cell Carcinoma of the Oropharynx\|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity\|Salivary Gland Squamous Cell Carcinoma\|Stage IV Squamous Cell Carcinoma of the Hypopharynx\|Stage IV Squamous Cell Carcinoma of the Larynx\|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity\|Stage IV Squamous Cell Carcinoma of the Nasopharynx\|Stage IV Squamous Cell Carcinoma of the Oropharynx\|Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity	March 2003	Phase 1\|Phase 2
NCT00915603	SCRI Development Innovations, LLC\|Novartis	Metastatic Breast Cancer	July 2009	Phase 2
NCT00217503	National Cancer Institute (NCI)	Lymphoma	July 2005	Phase 2
NCT04008030	Bristol-Myers Squibb\|Ono Pharmaceutical Co. Ltd	Metastatic Colorectal Cancer	August 5, 2019	Phase 3
NCT00924820	M.D. Anderson Cancer Center\|Genentech, Inc.	Neoplastic Meningitis	June 2009	Phase 1\|Phase 2
NCT00387751	National Cancer Institute (NCI)	Recurrent Melanoma\|Stage III Skin Melanoma\|Stage IV Skin Melanoma	August 2006	Phase 2
NCT00803062	National Cancer Institute (NCI)\|NRG Oncology	Cervical Adenocarcinoma\|Cervical Adenosquamous Carcinoma\|Cervical Squamous Cell Carcinoma\|Recurrent Cervical Carcinoma\|Stage IVB Cervical Cancer	April 2009	Phase 3
NCT05239741	Merck Sharp & Dohme LLC	Colorectal Neoplasms	April 2, 2022	Phase 3
NCT01212822	Fox Chase Cancer Center\|National Cancer Institute (NCI)	Adenocarcinoma of the Esophagus\|Adenocarcinoma of the Gastroesophageal Junction\|Diffuse Adenocarcinoma of the Stomach\|Intestinal Adenocarcinoma of the Stomach\|Mixed Adenocarcinoma of the Stomach\|Squamous Cell Carcinoma of the Esophagus\|Stage IA Esophageal Cancer\|Stage IA Gastric Cancer\|Stage IB Esophageal Cancer\|Stage IB Gastric Cancer\|Stage IIA Esophageal Cancer\|Stage IIA Gastric Cancer\|Stage IIB Esophageal Cancer\|Stage IIB Gastric Cancer\|Stage IIIA Esophageal Cancer\|Stage IIIA Gastric Cancer\|Stage IIIB Esophageal Cancer\|Stage IIIB Gastric Cancer\|Stage IIIC Esophageal Cancer\|Stage IIIC Gastric Cancer	April 27, 2011	Phase 2
NCT01417494	Federation Francophone de Cancerologie Digestive\|Roche Pharma AG	Colorectal Cancer	July 2011	Phase 2
NCT01004172	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital\|Beth Israel Deaconess Medical Center\|Genentech, Inc.	Metastatic Breast Cancer\|Breast Cancer\|Progressive Breast Cancer	November 2009	Phase 2
NCT02594423	University of Nottingham	Corneal Neovascularisation	December 2015	Phase 4
NCT00709657	Medical University of Vienna	Macular Degeneration\|Regional Blood Flow\|Vascular Endothelial Growth Factor	March 2008	Not Applicable
NCT00278889	AstraZeneca	Colorectal Cancer	January 2006	Phase 2
NCT05438108	Huazhong University of Science and Technology	Metastatic Colorectal Cancer	July 1, 2022	Phase 2
NCT02314377	University of California, San Francisco	Brain Arteriovenous Malformation	June 2016	Phase 1
NCT02272413	Boehringer Ingelheim	Carcinoma, Non-Small-Cell Lung	July 8, 2015	Phase 3
NCT00335829	Yale University\|National Cancer Institute (NCI)\|Northwestern University	Liver Cancer	May 2006	Phase 2
NCT01831089	PharmaMar	Breast Cancer\|Ovarian Cancer\|Gynecological Cancer\|Head and Neck Carcinoma\|Non-small Cell Lung Cancer\|Small Cell Lung Cancer\|Non-squamous Cell Lung Cancer	September 2013	Phase 1
NCT01860586	Wills Eye	Retinal Detachment\|Vitreoretinopathy Proliferative	June 2013	Not Applicable
NCT00368992	National Cancer Institute (NCI)	Adenocarcinoma of the Lung\|Adenosquamous Cell Lung Cancer\|Bronchoalveolar Cell Lung Cancer\|Large Cell Lung Cancer\|Recurrent Non-small Cell Lung Cancer\|Squamous Cell Lung Cancer\|Stage IIIB Non-small Cell Lung Cancer\|Stage IV Non-small Cell Lung Cancer	August 2006	Phase 2
NCT02299999	UNICANCER\|Fondation ARC\|AstraZeneca	Metastatic Breast Cancer	April 7, 2014	Phase 2
NCT05462613	Centre Hospitalier Universitaire de Besancon	Metastatic Colorectal Cancer	November 2022	Phase 2\|Phase 3
NCT03631836	Assistance Publique Hopitaux De Marseille	Glioblastoma	January 1, 2019	Phase 1
NCT02312245	Mayo Clinic\|National Cancer Institute (NCI)	Recurrent Fallopian Tube Carcinoma\|Recurrent Ovarian Carcinoma\|Recurrent Primary Peritoneal Carcinoma	July 21, 2015	Phase 2
NCT01089413	Hoffmann-La Roche	Colorectal Cancer	January 2010
NCT01164189	European Organisation for Research and Treatment of Cancer - EORTC\|Hoffmann-La Roche	Central Nervous System Tumors	February 2011	Phase 2
NCT05303038	Fudan University	Metastatic Breast Cancer in the Liver	May 1, 2022	Phase 2
NCT04988191	Peking University	Colorectal Carcinoma	December 24, 2020	Phase 1\|Phase 2
NCT00973609	AIO-Studien-gGmbH\|Roche Pharma AG	Colorectal Neoplasms	August 2009	Phase 3
NCT00735241	Sirtex Medical	Colorectal Carcinoma\|Liver Metastases	July 2008	Phase 2\|Phase 3
NCT02292758	Academic and Community Cancer Research United\|National Cancer Institute (NCI)	Colorectal Adenocarcinoma\|RAS Wild Type\|Stage IV Colorectal Cancer AJCC v7\|Stage IVA Colorectal Cancer AJCC v7\|Stage IVB Colorectal Cancer AJCC v7	December 12, 2014	Phase 2
NCT00883688	M.D. Anderson Cancer Center\|CERN Foundation - Collaborative Ependymoma Research Network	Brain Cancer\|Pediatric Cancers	July 2009	Phase 2
NCT00621686	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors	September 2008	Phase 2
NCT04486352	Alliance Foundation Trials, LLC.\|Genentech, Inc.\|Foundation Medicine\|Pfizer	Endometrial Cancer	October 20, 2021	Phase 1\|Phase 2
NCT00234052	Northwestern University\|National Cancer Institute (NCI)	Lung Cancer	July 28, 2005	Phase 2
NCT00126490	National Cancer Institute (NCI)	Recurrent Renal Cell Carcinoma\|Stage IV Renal Cell Cancer	March 2005	Phase 2
NCT00327093	Hospices Civils de Lyon	Colorectal Cancer\|Neoplasm Metastasis	May 2006	Phase 4
NCT01684397	Roswell Park Cancer Institute\|GlaxoSmithKline	Clear Cell Renal Cell Carcinoma\|Stage IV Renal Cell Cancer	November 21, 2012	Phase 1\|Phase 2
NCT04487067	Hoffmann-La Roche	Carcinoma, Hepatocellular	August 25, 2020	Phase 3
NCT00658697	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Beth Israel Deaconess Medical Center\|Genentech, Inc.	Prostate Cancer	June 2008	Phase 2
NCT05160896	Second Affiliated Hospital, School of Medicine, Zhejiang University	Advanced Metastatic Colorectal Cancer	November 12, 2021	Phase 2
NCT04541173	Aiwu Ruth He, MD\|Georgetown University\|Genentech, Inc.\|Hoosier Cancer Research Network	Hepatocellular Carcinoma	November 30, 2020	Phase 2
NCT02655536	National Taiwan University Hospital	Carcinoma, Non-Small-Cell Lung\|Brain Neoplasms	August 1, 2017	Phase 2
NCT00307723	Massachusetts General Hospital\|Dana-Farber Cancer Institute\|Beth Israel Deaconess Medical Center\|Genentech, Inc.\|Sanofi	Pancreatic Cancer\|Pancreatic Ductal Adenocarcinoma	May 2006	Phase 1\|Phase 2
NCT03698162	University of Southern California\|National Cancer Institute (NCI)	Brain Metastases\|Glioma of Brain\|Brain Tumor\|Metastatic Melanoma	April 13, 2021	Not Applicable
NCT00406744	Asociación para Evitar la Ceguera en México	Age Related Macular Degeneration\|Choroidal Neovascularization	May 2006	Phase 3
NCT03832179	Bay Area Retina Associates\|Allergan	Diabetic Macular Edema\|Cataract	November 15, 2018	Phase 4
NCT00609765	H. Lee Moffitt Cancer Center and Research Institute\|Genentech, Inc.	Pancreatic Cancer	August 2007	Phase 2
NCT01183663	M.D. Anderson Cancer Center\|Celgene	Advanced Cancers	August 2010	Phase 1
NCT03647956	The University of Hong Kong	NSCLC Stage IIIB\|NSCLC Stage IV\|EGFR Activating Mutation	October 1, 2018	Phase 2
NCT00416494	Herbert Hurwitz, MD\|National Cancer Institute (NCI)\|Duke University	Colorectal Cancer	September 2003	Phase 2
NCT03271255	Shenzhen People´s Hospital	Colorectal Neoplasms\|Intestinal Neoplasms\|Gastrointestinal Neoplasms\|Digestive System Neoplasms	May 23, 2018	Phase 2
NCT05273814	Tianjin Medical University Cancer Institute and Hospital	Non-Small Cell Lung Cancer	August 1, 2022	Phase 1
NCT00118105	Southwest Oncology Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Colorectal Cancer\|Metastatic Cancer	November 2006	Phase 2
NCT03167164	ImmunityBio, Inc.	Merkel Cell Carcinoma	December 2017	Phase 1\|Phase 2
NCT00774241	Hoffmann-La Roche	Breast Cancer	January 2010	Phase 4
NCT05173298	CHA University\|Boryung Pharmaceutical Co., Ltd	Advanced Hepatocellular Carcinoma	August 2, 2021
NCT03511963	Shanghai Henlius Biotech	Metastatic Colorectal Cancer (mCRC)	April 9, 2018	Phase 3
NCT00467194	National Cancer Centre, Singapore	Liver Cancer	December 2006	Phase 1
NCT04796025	Sun Yat-sen University	Hepatocellular Carcinoma	September 23, 2021	Phase 2
NCT01399684	Genentech, Inc.	Metastatic Colorectal Cancer	November 2011	Phase 2
NCT01067469	M.D. Anderson Cancer Center	Brain Cancer\|Glioblastoma	January 2010	Phase 2
NCT02794571	Genentech, Inc.	Advanced+Metastatic Tumors	May 23, 2016	Phase 1
NCT05070104	Cornerstone Pharmaceuticals	C04.588.274.476.411.307	March 30, 2023	Phase 1
NCT04952571	Beijing Sanbo Brain Hospital	Recurrent Glioblastoma	May 1, 2021	Phase 2
NCT01144988	Medical University Innsbruck\|Roche, Austria	Recurrent Malignant Glioma	March 2010	Phase 2
NCT00656435	National Taiwan University Hospital	Proliferative Diabetic Retinopathy	December 2006	Phase 3
NCT02350530	Sun Yat-sen University	Metastatic Colorectal Cancer	January 2015	Phase 2
NCT05065021	University Health Network, Toronto\|GlaxoSmithKline	Ovarian Cancer\|Fallopian Tube Cancer\|Primary Peritoneal Cancer\|High Grade Serous Cancer\|High Grade Endometrioid Cancer	June 6, 2022	Phase 2
NCT00407563	Accelerated Community Oncology Research Network\|Genentech, Inc.\|Celgene Corporation	Epithelial Ovarian Cancer\|Primary Peritoneal Carcinoma	January 2007	Phase 2
NCT01093235	Cambridge University Hospitals NHS Foundation Trust\|National Cancer Institute (NCI)	Breast Cancer\|Cardiac Toxicity\|Perioperative+Postoperative Complications	April 2009	Phase 3
NCT05571267	IVERIC bio, Inc.	Macular Degeneration	October 20, 2016	Phase 2
NCT00445406	Swiss Group for Clinical Cancer Research	Breast Cancer	December 2006	Phase 2
NCT02414165	Tocagen Inc.	Glioblastoma Multiforme\|Anaplastic Astrocytoma	November 30, 2015	Phase 2\|Phase 3
NCT01209442	University of Colorado, Denver\|Genentech, Inc.	Glioblastoma Multiforme	September 16, 2010	Phase 2
NCT00365365	Sanofi	Breast Cancer	August 2006	Phase 2
NCT00828672	Universitaire Ziekenhuizen KU Leuven	Locally Advanced Rectal Cancer	June 2009	Phase 2
NCT01640405	Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)\|Roche Pharma AG	Metastatic Colorectal Cancer	July 2012	Phase 3
NCT01664182	National Cancer Institute (NCI)	Advanced Renal Cell Carcinoma\|Advanced Sarcomatoid Renal Cell Carcinoma\|Stage III Renal Cell Cancer AJCC v7\|Stage IV Renal Cell Cancer AJCC v7	August 1, 2012	Phase 2
NCT04705519	Peking University\|Qilu Pharmaceutical Co., Ltd.	Neuroendocrine Carcinoma	January 5, 2021	Phase 2
NCT00670982	Harold J. Burstein, MD, PhD\|Brigham and Women´s Hospital\|Beth Israel Deaconess Medical Center\|Massachusetts General Hospital\|Genentech, Inc.\|New Hampshire Oncology-Hematology PA\|Lowell General Hospital\|Hartford Hospital\|Dana-Farber Cancer Institute	Breast Cancer	May 2008	Phase 2
NCT04356729	Elizabeth Buchbinder\|Genentech, Inc.\|Dana-Farber Cancer Institute	Clinical Stage III Cutaneous Melanoma AJCC v8\|Stage IV Melanoma\|Unresectable Stage III Cutaneous Melanoma\|Unresectable Stage IV Cutaneous Melanoma	August 6, 2020	Phase 2
NCT00434356	Genentech, Inc.	Metastatic Breast Cancer	March 2007	Phase 2
NCT00203372	Translational Oncology Research International\|Genentech, Inc.	Breast Cancer	May 2005	Phase 2
NCT01164007	Hoffmann-La Roche	Malignant Melanoma	June 30, 2006	Phase 2
NCT00280007	Medical University of Vienna	Hepatocellular Carcinoma	January 2006	Phase 2
NCT00423696	UNICANCER	Colorectal Cancer	March 23, 2006	Phase 2
NCT01722162	Washington University School of Medicine	Colorectal Neoplasms	April 2013	Phase 2
NCT05537402	University of Texas Southwestern Medical Center\|Genentech, Inc.	Hepatocellular Carcinoma	January 1, 2023	Phase 2
NCT05440708	Tvardi Therapeutics, Incorporated	Hepatocellular Carcinoma	November 2022	Phase 1\|Phase 2
NCT00525525	University of California, San Francisco	Glioblastoma\|Gliosarcoma	September 2007	Phase 2
NCT01392209	Memorial Sloan Kettering Cancer Center\|Genentech, Inc.\|Columbia University\|University of California, San Francisco	Brain Cancer\|MALIGNANT GLIOMA\|Glioblastoma\|Anaplastic Astrocytoma (AA)\|Anaplastic Oligodendroglioma (AO)\|Anaplastic Oligo-astrocytoma (AOA)\|Anaplastic Mixed Gliomas\|Malignant Glioma NOS	July 8, 2011	Phase 1
NCT01788280	University of Utah	Glioblastoma Multiforme (GBM)	January 2018	Phase 2
NCT03587311	National Cancer Institute (NCI)	Fallopian Tube Endometrioid Adenocarcinoma\|Fallopian Tube High Grade Serous Adenocarcinoma\|Ovarian Endometrioid Adenocarcinoma\|Ovarian High Grade Serous Adenocarcinoma\|Platinum-Resistant Fallopian Tube Carcinoma\|Platinum-Resistant Ovarian Carcinoma\|Platinum-Resistant Primary Peritoneal Carcinoma\|Primary Peritoneal High Grade Serous Adenocarcinoma	June 29, 2018	Phase 2
NCT00590681	University of Chicago\|Genentech, Inc.	Glioblastoma Multiforme	February 2007	Phase 2
NCT00546156	Ian E. Krop, MD, PhD\|Genentech, Inc.\|Massachusetts General Hospital\|Brigham and Women´s Hospital\|New Hampshire Oncology-Hematology PA\|Dana-Farber Cancer Institute	Breast Cancer	October 2007	Phase 2
NCT00854529	Rabin Medical Center	Bleb Vascularity\|Bleb Fibrosis\|Trabeculectomy Failure	April 2009	Phase 2
NCT00970957	Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA	Macular Edema\|Retinal Vein Occlusion	September 2009	Phase 3
NCT00773188	Hoffmann-La Roche	Non-Squamous Non-Small Cell Lung Cancer	December 2008	Phase 1
NCT00418431	Asociación para Evitar la Ceguera en México	Central Serous Chorioretinopathy	April 2006	Phase 2\|Phase 3
NCT01191697	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital\|Genentech, Inc.	Esophageal Cancer\|Gastric Cancer	February 2011	Phase 2
NCT05386524	Fudan University	Breast Cancer	June 15, 2022	Phase 2
NCT03387098	ImmunityBio, Inc.	Pancreatic Cancer	January 2, 2018	Phase 1\|Phase 2
NCT01738646	Duke University\|Genentech, Inc.\|Merck Sharp & Dohme LLC	Recurrent Glioblastoma Multiforme\|Malignant Glioma\|Adult Brain Tumor	January 2013	Phase 2
NCT02024607	Sumitomo Pharma Oncology, Inc.	Advanced Gastrointestinal Cancer	January 2014	Phase 1\|Phase 2
NCT02623621	Azienda Ospedaliero, Universitaria Pisana	Metastatic Colorectal Cancer	November 2015
NCT03303495	Sun Yat-sen University	Colorectal Neoplasms\|Neoplasm Metastasis\|Intestinal Neoplasms\|Gastrointestinal Neoplasms\|Digestive System Neoplasms	November 14, 2011	Phase 3
NCT00623233	Eli Lilly and Company\|Genentech, Inc.	Metastatic Breast Cancer\|Locally Advanced Breast Cancer	March 2008	Phase 2
NCT01198158	National Cancer Institute (NCI)	Clear Cell Renal Cell Carcinoma\|Recurrent Renal Cell Carcinoma\|Stage III Renal Cell Cancer AJCC v7\|Stage IV Renal Cell Cancer AJCC v7	September 15, 2010	Phase 3
NCT01015222	M.D. Anderson Cancer Center	Advanced Cancer	November 2009	Phase 1
NCT00497497	Genentech, Inc.	Colorectal Cancer	October 2007	Phase 1
NCT02314182	Hospices Civils de Lyon	Rectal Adenocarcinoma	November 20, 2014	Phase 3
NCT04449874	Genentech, Inc.	Non-Small Cell Lung Cancer\|Colorectal Cancer\|Advanced Solid Tumors	July 29, 2020	Phase 1
NCT00345696	Unidad Integral de Investigación en Oncología S.L.\|Hoffmann-La Roche	Metastatic Colorectal Cancer	June 2006	Phase 2
NCT00659022	Radboud University Medical Center	Colorectal Neoplasms\|Liver Neoplasms	July 2008	Phase 2
NCT01206530	Abramson Cancer Center of the University of Pennsylvania	Rectal Cancer\|Colon Cancer\|Metastasis\|Adenocarcinoma	September 2010	Phase 1\|Phase 2
NCT03556839	Grupo Español de Investigación en Cáncer de Ovario\|Hoffmann-La Roche\|ARCAGY+ GINECO GROUP\|Multicenter Italian Trials in Ovarian cancer and gynecologic malignancies\|MaNGO\|NSGO\|Japanese Gynecologic Oncology Group\|Gynecologic Oncology Group Foundation\|AGO Study Group	Carcinoma of the Cervix, Stage IVB	September 25, 2018	Phase 3
NCT02959749	Qingdao Central Hospital	Progression Free Survival	August 2015	Phase 2\|Phase 3
NCT02488330	Hoffmann-La Roche	Solid Tumor	August 27, 2015	Phase 3
NCT02497157	Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan\|Hiroshima Prefectural Hospital\|National Hospital Organization Shikoku Cancer Center	Metastatic Colorectal Cancer	May 21, 2015	Phase 2
NCT00480831	Genentech, Inc.	Non-Small Cell Lung Cancer	June 2007	Phase 2
NCT00404404	Premiere Oncology\|National Cancer Institute (NCI)	Breast Cancer	October 2006	Phase 2
NCT00348998	Virginia Mason Hospital+Medical Center\|National Cancer Institute (NCI)	Prostate Cancer	April 2006	Phase 2
NCT03806049	Nordic Society of Gynaecological Oncology - Clinical Trials Unit	Ovarian Cancer	December 2019	Phase 3
NCT00876993	Johns Hopkins All Children´s Hospital\|The V Foundation\|Brain Tumor Alliance	Central Nervous System Tumors	September 2008	Phase 1
NCT00318136	Genentech, Inc.	Non-small Cell Lung Cancer	September 2005	Phase 2
NCT02582970	Hoffmann-La Roche	Colorectal Cancer	May 2005	Phase 4
NCT00015951	University of Maryland, Baltimore\|National Cancer Institute (NCI)\|University of Maryland Greenebaum Cancer Center	Leukemia\|Myelodysplastic Syndromes	April 2001	Phase 2
NCT04466917	Amgen\|Parexel	Metastatic Non-small Cell Lung Cancer (NSCLC)\|Non-squamous NSCLC	May 15, 2021	Phase 3
NCT04938583	CanariaBio Inc.\|Korean Cancer Study Group	Ovarian Cancer by FIGO Stage\|Ovarian Cancer Stage III\|Ovarian Cancer Stage IV	March 17, 2021	Phase 1\|Phase 2
NCT00409565	National Cancer Institute (NCI)	Head and Neck Cancer\|Squamous Cell Carcinoma	September 2006	Phase 2
NCT00268450	Medical University of South Carolina	Bladder Cancer	September 21, 2005	Phase 2
NCT01306591	Peking University People´s Hospital	Exudative Age-related Macular Degeneration	January 2008	Not Applicable
NCT01622543	Canadian Cancer Trials Group\|Oncolytics Biotech	Colorectal Cancer	June 11, 2012	Phase 2
NCT02698254	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Recurrent Brain Neoplasm	July 20, 2016	Not Applicable
NCT00853073	Wills Eye	Glaucoma	February 2009	Phase 2\|Phase 3
NCT00643565	Hoffmann-La Roche	Sarcoma	July 29, 2008	Phase 2
NCT01858649	Cliniques universitaires Saint-Luc- Université Catholique de Louvain\|Grand Hôpital de Charleroi	Metastatic Colorectal Cancer	May 2013	Phase 2
NCT03240549	Beijing Hospital	Non-small Cell Lung Cancer Metastatic	August 2017	Phase 2
NCT00468429	Grewal Eye Institute	Glaucoma	May 2007	Phase 4
NCT03367182	Yonsei University	Ovarian Cancer	September 1, 2017
NCT00317200	Hoosier Cancer Research Network\|Genentech, Inc.\|Walther Cancer Institute	Small Cell Lung Cancer	April 2006	Phase 2
NCT00642577	Hoffmann-La Roche	Colorectal Cancer	July 2007	Phase 3
NCT03321513	Jaeb Center for Health Research	Diabetic Macular Edema	December 7, 2017	Phase 3
NCT00376701	Lawson Health Research Institute\|QLT Inc.\|Canadian Retinal Trials Group	Age Related Macular Degeneration	September 2006	Phase 2
NCT03694262	Medical College of Wisconsin\|Genentech, Inc.\|Clovis Oncology, Inc.	Endometrial Cancer\|Uterine Carcinosarcoma	July 19, 2019	Phase 2
NCT00550537	Vanderbilt-Ingram Cancer Center\|National Cancer Institute (NCI)	Lung Cancer	October 2007	Phase 2
NCT00126503	National Cancer Institute (NCI)	Chromophobe Renal Cell Carcinoma\|Clear Cell Renal Cell Carcinoma\|Papillary Renal Cell Carcinoma\|Recurrent Renal Cell Carcinoma\|Sarcomatoid Renal Cell Carcinoma\|Stage IV Renal Cell Cancer	May 2005	Phase 1\|Phase 2
NCT00027599	National Cancer Institute (NCI)	Prostate Cancer	December 2001	Phase 2
NCT00661778	Hoffmann-La Roche	Non-small Cell Lung Cancer	July 2007	Phase 2
NCT00417976	Tony Bekaii-Saab\|Genentech, Inc.\|Ohio State University Comprehensive Cancer Center	Pancreatic Cancer	December 2006	Phase 2
NCT00879437	Baylor College of Medicine\|Cook Children´s Medical Center\|University of Oklahoma\|University of Texas, Southwestern Medical Center at Dallas\|The University of Texas Health Science Center at San Antonio\|M.D. Anderson Cancer Center	Glial Cell Tumors\|Malignant Gliomas\|Glioblastoma Multiforme\|Anaplastic Astrocytoma\|Gliomatosis Cerebri\|Gliosarcoma\|Brainstem Glioma\|Diffuse Intrinsic Pontine Glioma	September 1, 2009	Phase 2
NCT01014468	Instituto de Olhos de Goiania	Age Related Macular Degeneration	March 2009	Phase 3
NCT02250599	Sun Yat-sen University	Nasopharyngeal Neoplasms	August 2014	Phase 2
NCT00631371	Pfizer	Renal Cell Carcinoma	April 2008	Phase 3
NCT00705874	Progen Pharmaceuticals	Cancer	May 2006	Phase 1
NCT04425187	Fudan University	PFS	June 8, 2020	Phase 2
NCT05191784	Genexine, Inc.	Recurrent Glioblastoma	January 26, 2022	Phase 2
NCT00805649	Johann Wolfgang Goethe University Hospital	Age-Related Macular Degeneration	January 2006	Phase 4
NCT02187302	NewLink Genetics Corporation\|Lumos Pharma	Metastatic Renal Cell Carcinoma	July 2014	Phase 2
NCT01305213	National Cancer Institute (NCI)\|NRG Oncology	Recurrent Fallopian Tube Carcinoma\|Recurrent Ovarian Carcinoma\|Recurrent Primary Peritoneal Carcinoma	March 21, 2011	Phase 2
NCT02925234	The Netherlands Cancer Institute\|Amgen\|AstraZeneca\|Bayer\|Bristol-Myers Squibb\|Novartis\|Roche Pharma AG\|Merck Sharp & Dohme LLC\|Boehringer Ingelheim\|Ipsen\|Eisai Inc.\|Pfizer\|Clovis Oncology, Inc.\|Eli Lilly and Company\|Janssen, LP	Cancer\|Tumors\|Neoplasm\|Neoplasia	August 2016	Phase 2
NCT00530907	M.D. Anderson Cancer Center	Advanced Cancer	June 2007	Phase 1
NCT01792934	Radboud University Medical Center\|Erasmus Medical Center	Multi-organ Metastatic Colorectal Cancer	May 2013	Not Applicable
NCT01314274	Medical University of Vienna	HHT\|Morbus Osler\|Epistaxis	March 2011	Phase 2
NCT01765582	Hoffmann-La Roche	Colorectal Neoplasms	January 23, 2013	Phase 2
NCT00381797	National Cancer Institute (NCI)	Childhood Cerebral Anaplastic Astrocytoma\|Childhood Oligodendroglioma\|Childhood Spinal Cord Neoplasm\|Recurrent Childhood Brain Stem Glioma\|Recurrent Childhood Ependymoma\|Recurrent Childhood Medulloblastoma	August 2006	Phase 2
NCT03452579	Case Comprehensive Cancer Center	Glioblastoma	May 21, 2018	Phase 2
NCT00252564	US Oncology Research\|Bristol-Myers Squibb\|Memorial Sloan Kettering Cancer Center\|Prologue Research International	Metastatic Colorectal Cancer	September 2005	Phase 3
NCT03082209	AbbVie	Advanced Solid Tumors\|Cancer\|Hematologic Malignancies	March 20, 2017	Phase 1
NCT00620971	Hellenic Oncology Research Group\|University Hospital of Crete	Non Small Cell Lung Cancer	January 2008	Phase 2
NCT05318443	Shanghai Institute Of Biological Products\|Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Non-squamous Non-small-cell Lung Cancer	April 17, 2020	Phase 3
NCT01232777	Vision Research Foundation	Retinopathy of Prematurity	June 2012	Phase 2
NCT05616390	Tianjin Medical University Cancer Institute and Hospital	Hepatocellular Carcinoma	November 2022	Phase 2
NCT00121134	Harold J. Burstein, MD, PhD\|Genentech, Inc.\|Beth Israel Deaconess Medical Center\|Indiana University School of Medicine\|University of California, San Francisco\|University of North Carolina\|Dana-Farber Cancer Institute	Breast Cancer	June 2005	Not Applicable
NCT00745511	Ora Bio Ltd.	Macular Degeneration	March 2009	Phase 1\|Phase 2
NCT00666692	Abbott	Non-small Cell Lung Cancer	April 2008	Phase 1
NCT04393220	Fuda Cancer Hospital, Guangzhou	Progress Free Survival (PFS) and Overall Survival (OS)	May 11, 2020	Phase 2
NCT01115491	Hoffmann-La Roche	Glioblastoma Multiforme	June 2010	Phase 2
NCT02698280	Huashan Hospital	Glioblastoma	July 2015	Phase 2
NCT00786669	Children´s Hospital Medical Center, Cincinnati	Solid Tumor	October 2008	Phase 1
NCT00365144	University of California, San Francisco	Pancreatic Cancer	February 2006	Phase 2
NCT04524871	Hoffmann-La Roche\|Sanofi\|Tempest Therapeutics	Advanced Liver Cancers	November 2, 2020	Phase 1\|Phase 2
NCT01706120	National Cancer Institute, Naples\|Mario Negri Institute for Pharmacological Research	Ovarian Cancer	October 2012	Phase 4
NCT02305758	AbbVie	Untreated Metastatic Colorectal Cancer	December 2, 2014	Phase 2
NCT01731158	Central European Society for Anticancer Drug Research	Metastatic Renal Cell Carcinoma	October 2012	Phase 2
NCT00815594	Capital Medical University	Bleb Vascularity\|Conjunctival Scarring	December 2008	Phase 4
NCT03897192	Changhua Christian Hospital	Punctate Inner Choroidopathy	October 1, 2018
NCT01745757	UNICANCER	Metastatic\|Breast Cancer	June 2012
NCT00766246	Pharmatech\|Genentech, Inc.\|Sanofi	Non-small Cell Lung Cancer Stage IIIB\|Non-small Cell Lung Cancer Stage IV	October 2008	Phase 2
NCT01115517	The University of Texas Health Science Center, Houston\|Hermann Eye Center	Pterygium	October 2010	Phase 2
NCT04601688	He Eye Hospital	Branch Retinal Vein Occlusion	October 31, 2020	Not Applicable
NCT05044871	Tongji Hospital\|Qilu Hospital of Shandong University\|Hubei Cancer Hospital\|Hunan Cancer Hospital\|Peking University Cancer Hospital & Institute\|Obstetrics and Gynecology Hospital of Zhejiang University\|Sun Yat-sen University\|Anhui Provincial Cancer Hospital\|Jilin Provincial Tumor Hospital\|First Affiliated Hospital, Sun Yat-Sen University\|Affiliated Hospital of Jiangnan University	Ovarian Cancer	January 1, 2023	Phase 2
NCT00924209	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	NSCLC\|Stage IIIA (N2)	March 2009	Phase 2
NCT00118755	Hoffmann-La Roche	Colorectal Cancer	July 2005	Phase 2
NCT00025233	National Cancer Institute (NCI)\|Gynecologic Oncology Group	Cervical Squamous Cell Carcinoma\|Recurrent Cervical Cancer	April 2002	Phase 2
NCT01912443	Sun Yat-sen University\|Proswell Medical Corporation	Metastatic Colorectal Cancer	August 2013
NCT01705002	Lipomedix Pharmaceuticals Inc.	Cancer\|Solid Tumor\|Metastatic Colorectal Cancer (mCRC)	October 2012	Phase 1
NCT00536939	Eli Lilly and Company\|Genentech, Inc.	Breast Cancer	November 2007	Phase 2
NCT00378066	Asan Medical Center	Metastatic Colorectal Cancer	August 2006	Phase 2
NCT02354612	Tracon Pharmaceuticals Inc.	Solid Tumors
NCT01920984	National Taiwan University Hospital	Proliferative Diabetic Retinopathy	January 2005	Not Applicable
NCT01823081	Shahid Beheshti University of Medical Sciences	Diabetic Macular Edema	January 2013	Phase 3
NCT00898794	Kantonsspital Graubuenden\|National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific\|Unspecified Childhood Solid Tumor, Protocol Specific	October 2007
NCT00690768	University of Sao Paulo	Diabetic Retinopathy\|Retinal Detachment	March 2008	Phase 2
NCT00694200	Hellenic Oncology Research Group\|University Hospital of Crete	Breast Cancer	April 2008	Phase 2
NCT05446870	Merck Sharp & Dohme LLC	High-grade Serous Ovarian Carcinoma\|Ovarian Carcinoma	July 25, 2022	Phase 2
NCT01206049	Vejle Hospital	Cholangiocarcinoma	September 2010	Phase 2
NCT00879359	The Cleveland Clinic\|Genentech, Inc.	Endometrial Carcinoma	December 2007	Phase 2
NCT00890786	Children´s Hospital Medical Center, Cincinnati\|Genentech, Inc.	Newly Diagnosed High-Grade Gliomas\|Diffuse Intrinsic Pontine Glioma	May 2009	Early Phase 1
NCT00098787	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Colorectal Cancer	July 2005	Phase 2
NCT00140556	David M. Brizel, MD\|Genentech, Inc.\|OSI Pharmaceuticals\|Duke University	Head and Neck Cancer\|Pharynx Cancer	August 2005	Early Phase 1
NCT02669173	Case Comprehensive Cancer Center	Glioblastoma	October 11, 2016	Phase 1
NCT02715531	Hoffmann-La Roche	Solid Tumor	April 6, 2016	Phase 1
NCT00559715	Klinikum Bremen-Mitte, gGmbH\|Kompetenzzentrum für Klinische Studien, Bremen	Age-Related Neovascular Macular Degeneration	August 2008	Phase 3
NCT00671372	Genentech, Inc.	Colorectal Cancer	July 2006	Phase 1
NCT00868634	iOMEDICO AG\|Arbeitsgemeinschaft fur Internistische Onkologie\|Arbeitskreis Klinische Studien\|Roche Pharma AG	Metastatic Breast Cancer	February 2009	Phase 3
NCT00885326	New Approaches to Neuroblastoma Therapy Consortium\|National Cancer Institute (NCI)	Neuroblastoma	December 2009	Phase 1
NCT00142467	Massachusetts General Hospital\|Dana-Farber Cancer Institute\|Beth Israel Deaconess Medical Center\|Brigham and Women´s Hospital\|Genentech, Inc.\|Sanofi-Synthelabo\|Eli Lilly and Company	Hepatocellular Carcinoma	April 2004	Phase 2
NCT00359164	University of British Columbia	Macular Degeneration	July 2006	Phase 2
NCT01107626	ECOG-ACRIN Cancer Research Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Lung Cancer	August 12, 2010	Phase 3
NCT00749567	Hellenic Oncology Research Group\|University Hospital of Crete	Non-small-cell Lung Cancer	July 2008	Phase 2
NCT00254592	University of California, Irvine	Breast Cancer	October 2005	Phase 2
NCT01311050	King Faisal Specialist Hospital & Research Center	Metastatic Colorectal Cancer	January 2009
NCT03434379	Hoffmann-La Roche	Carcinoma, Hepatocellular	March 15, 2018	Phase 3
NCT00096278	National Cancer Institute (NCI)\|NSABP Foundation Inc	Colon Adenocarcinoma\|Stage IIA Colon Cancer AJCC v7\|Stage IIB Colon Cancer AJCC v7\|Stage IIC Colon Cancer AJCC v7\|Stage IIIA Colon Cancer AJCC v7\|Stage IIIB Colon Cancer AJCC v7\|Stage IIIC Colon Cancer AJCC v7	September 15, 2004	Phase 3
NCT01389505	Instituto do Coracao\|Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.	Proliferative Diabetic Retinopathy	February 2011	Phase 2
NCT02590094	Panhandle Eye Group, LLP	Diabetic Retinopathy	October 2015	Not Applicable
NCT02158520	Academic and Community Cancer Research United\|National Cancer Institute (NCI)	Metastatic Melanoma\|Mucosal Melanoma\|Stage IV Cutaneous Melanoma AJCC v6 and v7\|Stage IV Uveal Melanoma AJCC v7\|Unresectable Melanoma	October 18, 2013	Phase 2
NCT01193595	Sanofi	Neoplasms, Malignant	September 2010	Phase 1
NCT00025389	University of Chicago\|National Cancer Institute (NCI)	Lung Cancer	November 2001	Phase 2
NCT03693573	Hoffmann-La Roche	Renal Cell Carcinoma	January 11, 2019	Phase 3
NCT00354549	Swiss Group for Clinical Cancer Research	Lung Cancer	January 2006	Phase 2
NCT05118776	Ascletis Pharmaceuticals Co., Ltd.	Recurrent Glioblastoma	January 21, 2022	Phase 3
NCT01189240	National Cancer Institute (NCI)	Adult Anaplastic Astrocytoma\|Adult Anaplastic Oligodendroglioma\|Adult Giant Cell Glioblastoma\|Adult Glioblastoma\|Adult Gliosarcoma\|Recurrent Adult Brain Tumor	December 2010	Phase 1\|Phase 2
NCT01203306	University of Turin, Italy	Neuroendocrine Carcinomas	January 2006	Phase 2
NCT00675259	Ohio State University Comprehensive Cancer Center\|Celgene Corporation\|Genentech, Inc.	Breast Cancer	July 2008	Phase 2
NCT00203424	Translational Oncology Research International\|Genentech, Inc.	Prostate Cancer	January 2006	Phase 2
NCT00537901	King Faisal Specialist Hospital & Research Center	Colonic Neoplasms\|Rectal Neoplasms	October 2007	Not Applicable
NCT04553692	IGM Biosciences, Inc.	Solid Tumor\|Colorectal Cancer\|Non Hodgkin Lymphoma\|Sarcoma\|Chondrosarcoma\|Small Lymphocytic Lymphoma\|Chronic Lymphocytic Leukemia\|Acute Myeloid Leukemia	September 23, 2020	Phase 1
NCT02195336	Karl Kölbeck\|Karolinska University Hospital	Non-small Cell Lung Cancer	August 2014	Not Applicable
NCT02988843	Masonic Cancer Center, University of Minnesota	Germ Cell Tumor	March 29, 2017	Phase 2
NCT05305131	National University Hospital, Singapore	Nasopharyngeal Cancer	March 28, 2022	Phase 2
NCT00604461	H. Lee Moffitt Cancer Center and Research Institute\|Genentech, Inc.	Mesothelioma	October 2007	Phase 1\|Phase 2
NCT02393898	Hoffmann-La Roche	Ovarian Cancer	April 23, 2015
NCT00797303	Instituto de Olhos de Goiania	Corneal Neovascularization	January 2006	Phase 4
NCT03390686	Prestige Biopharma Limited	Lung Cancer\|Non-small Cell Lung Cancer	November 15, 2019	Phase 3
NCT00513266	Centre Hospitalier Universitaire Vaudois\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	June 2007	Phase 2
NCT01061515	Washington University School of Medicine	Carcinoma	May 10, 2011	Phase 1
NCT00088998	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Breast Cancer	December 2004	Phase 2
NCT03647592	Hunan Province Tumor Hospital	Non Small Cell Lung Cancer	June 1, 2018
NCT01832415	ARCAGY+ GINECO GROUP\|Roche Pharma AG	Epithelial Ovarian Cancer	April 2013
NCT00337389	Mast Therapeutics, Inc.	Metastatic Colorectal Cancer\|Colon Cancer\|Rectal Cancer	May 2006	Phase 3
NCT01818973	Sun Yat-sen University	Rectal Cancer	March 2013	Phase 2
NCT01468844	National Eye Institute (NEI)\|National Institutes of Health Clinical Center (CC)	Retinal Vein Occlusion	December 21, 2011	Phase 1\|Phase 2
NCT00438737	European Organisation for Research and Treatment of Cancer - EORTC\|National Cancer Institute (NCI)	Colorectal Cancer\|Metastatic Cancer	January 2007	Phase 2
NCT01580969	University of Utah	Recurrent Glioma	July 6, 2012	Phase 1\|Phase 2
NCT00265824	GERCOR - Multidisciplinary Oncology Cooperative Group	Colorectal Cancer	May 2005	Phase 3
NCT02078648	Stemline Therapeutics, Inc.	Adult Brain Glioblastoma\|Glioblastoma Multiforme	May 2014	Phase 1\|Phase 2
NCT00370786	Shahid Beheshti University of Medical Sciences	Choroidal Neovascularization	November 2005	Phase 3
NCT01125943	Radboud University Medical Center\|Dutch Cancer Society	Hypertension\|Cancer\|Endothelial Dysfunction	June 2010	Not Applicable
NCT01151722	University of Sao Paulo	Recurrent\|Hemorrhage	December 2009	Phase 2
NCT00541125	Federation Francophone de Cancerologie Digestive	Colorectal Cancer	November 2007	Phase 2
NCT02017717	Bristol-Myers Squibb	Recurrent Glioblastoma	February 7, 2014	Phase 3
NCT00217282	Mt. Sinai Medical Center, Miami\|Sanofi-Synthelabo\|Genentech, Inc.	Non-Small Cell Lung Cancer	June 2004	Phase 2
NCT00531336	The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery	Macular Degeneration	July 2006	Phase 2
NCT03197584	ImmunityBio, Inc.	Ovarian Cancer	December 2017	Phase 1\|Phase 2
NCT00782275	Beth Israel Deaconess Medical Center\|Genentech, Inc.\|Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Vanderbilt University Medical Center	Renal Cell Carcinoma\|Kidney Cancer	April 2009	Phase 2
NCT02898012	Assistance Publique - Hôpitaux de Paris\|Roche Pharma AG	Glioblastoma Multiforme\|Primary Brain Tumor	October 2010	Phase 2
NCT00416637	Herbert Hurwitz, MD\|National Cancer Institute (NCI)\|Duke University	Unspecified Adult Solid Tumor, Protocol Specific	January 2004	Phase 1
NCT02390531	Jaeb Center for Health Research\|Pediatric Eye Disease Investigator Group\|National Eye Institute (NEI)	Retinopathy of Prematurity	April 28, 2015	Phase 1
NCT04525326	Fudan University	Colorectal Cancer\|Liver Metastases	October 1, 2020	Phase 3
NCT05394233	Sichuan Cancer Hospital and Research Institute	Non-squamous Non-small Cell Lung Cancer\|EGFR Gene Mutation	June 1, 2022	Phase 2
NCT00576901	Hoffmann-La Roche	Breast Cancer	November 2007	Phase 2
NCT02515734	Japan Clinical Cancer Research Organization	Colorectal Cancer	August 2015	Phase 2
NCT04929223	Hoffmann-La Roche	Metastatic Colorectal Cancer	October 22, 2021	Phase 1
NCT05523440	University of Oklahoma\|GlaxoSmithKline	Recurrent Endometrial Carcinoma\|Recurrent Ovarian Carcinoma\|ARID1A Gene Mutation	January 2023	Phase 2
NCT00451763	University of Sao Paulo\|Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.	Retina\|Telangiectasis	January 2006	Phase 3
NCT00570531	University of Michigan Rogel Cancer Center\|Genentech, Inc.	Loco-regional Esophageal Cancer	June 2007	Phase 2
NCT04416035	Zhejiang Teruisi Pharmaceutical Inc.	Advanced Non-squamous Non-small-cell Lung Cancer	August 17, 2020	Phase 3
NCT00055692	National Cancer Institute (NCI)	Adult Primary Hepatocellular Carcinoma\|Localized Unresectable Adult Primary Liver Cancer\|Recurrent Adult Primary Liver Cancer	February 2003	Phase 2
NCT00682539	Medical University of Vienna	Diabetic Macular Edema	October 2007	Phase 4
NCT01190345	Institut Paoli-Calmettes	Breast Cancer	May 2010	Phase 2
NCT05192798	First Affiliated Hospital Bengbu Medical College	Triple-negative Breast Cancer	January 14, 2022	Phase 2
NCT01041690	Cairo University	Proliferative Diabetic Retinopathy	June 2007	Not Applicable
NCT00364611	Sanofi	Breast Cancer	August 2006	Phase 2
NCT01068977	Genentech, Inc.	Solid Cancers	August 2007	Phase 1
NCT00723255	National Cancer Institute (NCI)\|NRG Oncology	Recurrent Endometrial Carcinoma	September 2008	Phase 2
NCT01976923	J. Fernando Arevalo, MD FACS\|Pan American Collaborative Retina Study Group\|King Khaled Eye Specialist Hospital	Tractional Retinal Detachment Secondary to Proliferative Diabetic Retinopathy	November 2013	Phase 3
NCT00323869	Stanford University\|Eli Lilly and Company\|Genentech, Inc.	Lung Cancer\|Non-small Cell Lung Cancer (NSCLC)	June 2006	Phase 2
NCT04940546	Sun Yat-sen University	Colorectal Cancer Metastatic	June 16, 2021	Phase 1\|Phase 2
NCT01471054	Arman Mashayekhi\|Allergan\|Wills Eye	Macular Edema\|Cystoid Macular Edema\|Uveal Melanoma\|Radiation Maculopathy\|Radiation Retinopathy	April 2014	Phase 2
NCT01120158	Hellenic Oncology Research Group\|University Hospital of Crete	Breast Cancer	September 2009	Phase 2
NCT02734004	AstraZeneca\|Iqvia Pty Ltd	Ovarian\|Breast\|SCLC\|Gastric Cancers	March 17, 2016	Phase 1\|Phase 2
NCT03353324	Shahid Beheshti University of Medical Sciences	Retinal Vein Occlusion With Macular Edema	November 1, 2017	Phase 2\|Phase 3
NCT02250118	Institut Curie\|Henri Mondor University Hospital	Pleural Effusion, Malignant\|Breast Cancer	December 9, 2014	Phase 1
NCT03175432	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	BRAF V600 Wild Type\|Clinical Stage IV Cutaneous Melanoma AJCC v8\|Intracranial Melanoma\|Metastatic Malignant Neoplasm in the Brain\|Metastatic Melanoma\|Pathologic Stage IV Cutaneous Melanoma AJCC v8\|Refractory Melanoma	June 15, 2017	Phase 2
NCT00436215	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Ovarian Neoplasm\|Fallopian Tube Cancer\|Primary Peritoneal Cancer	December 12, 2006	Phase 2
NCT00801866	Asociación para Evitar la Ceguera en México	Macular Edema		Phase 4
NCT00077298	National Cancer Institute (NCI)	Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer	December 2003	Phase 2
NCT01091259	NYU Langone Health\|Genentech, Inc.	Ovarian Cancer\|Fallopian Tube Cancer\|Primary Peritoneal Carcinoma	March 2010	Phase 2
NCT01743950	University of Wisconsin, Madison\|Genentech, Inc.\|National Cancer Institute (NCI)	Glioma	December 3, 2012	Phase 2
NCT00447330	Duke University\|Hoffmann-La Roche\|Sanofi\|Genentech, Inc.	Esophageal Neoplasms\|Stomach Neoplasms\|Neoplasm Metastasis	February 2007	Phase 2
NCT00636610	Genentech, Inc.	Metastatic Colorectal Cancer	May 2008	Phase 2
NCT04072198	Gruppo Oncologico Italiano di Ricerca Clinica	Colorectal Cancer	September 26, 2019	Phase 2
NCT00845884	Rabin Medical Center	Advanced Gastric Cancer	February 2009	Phase 1\|Phase 2
NCT01274273	University of Aarhus\|Danish Renal Cancer Study Group	Metastatic Renal Cell Carcinoma	October 2009	Phase 2
NCT02627144	Hoffmann-La Roche	Renal Cell Cancer	January 2008
NCT04868708	Akeso	Recurrent or Metastatic Cervical Cancer	April 1, 2021	Phase 2
NCT00021060	National Cancer Institute (NCI)	Adenocarcinoma of the Lung\|Bronchoalveolar Cell Lung Cancer\|Large Cell Lung Cancer\|Recurrent Non-small Cell Lung Cancer\|Stage IIIB Non-small Cell Lung Cancer\|Stage IV Non-small Cell Lung Cancer	August 2002	Phase 2\|Phase 3
NCT00667485	University of Chicago\|Genentech, Inc.	Advanced Cancer\|Metastatic Cancer	April 2008	Phase 1
NCT02942043	Peking University Cancer Hospital & Institute\|Peking University First Hospital\|Peking University Third Hospital	Malignant Pleural Effusion	October 2016	Phase 2
NCT02623673	Retina Clinic, Sao Paulo, Brazil	Macular Edema	September 2015
NCT00705315	Hellenic Oncology Research Group	Breast Cancer	May 2008	Phase 1\|Phase 2
NCT03307785	Tesaro, Inc.	Neoplasms\|Metastatic Cancer\|Advanced Cancer\|Solid Tumor\|Non Small Cell Lung Cancer Metastatic\|Non Small Cell Lung Cancer Stage IIIB\|Non Small Cell Lung Cancer	October 12, 2017	Phase 1
NCT00741988	SCRI Development Innovations, LLC\|Bristol-Myers Squibb\|Genentech, Inc.	Non-Small Cell Lung Cancer	September 2008	Phase 2
NCT02606305	ImmunoGen, Inc.	Epithelial Ovarian Cancer\|Primary Peritoneal Cancer\|Fallopian Tube Cancer	December 2015	Phase 1\|Phase 2
NCT01005329	National Cancer Institute (NCI)\|Radiation Therapy Oncology Group	Endometrial Adenocarcinoma\|Endometrial Adenosquamous Carcinoma\|Endometrial Clear Cell Adenocarcinoma\|Endometrial Serous Adenocarcinoma\|Stage IA Uterine Corpus Cancer AJCC v7\|Stage IB Uterine Corpus Cancer AJCC v7\|Stage II Uterine Corpus Cancer AJCC v7\|Stage IIIA Uterine Corpus Cancer AJCC v7\|Stage IIIB Uterine Corpus Cancer AJCC v7\|Stage IIIC Uterine Corpus Cancer AJCC v7\|Stage IVA Uterine Corpus Cancer AJCC v7\|Stage IVB Uterine Corpus Cancer AJCC v7	November 6, 2009	Phase 2
NCT02413853	University of Southern California\|National Cancer Institute (NCI)\|Prism Pharma Co., Ltd.	Colorectal Adenocarcinoma\|Stage IVA Colorectal Cancer\|Stage IVB Colorectal Cancer	November 2015	Phase 2
NCT05197504	CHA University	Hepatocellular Carcinoma	December 20, 2021
NCT00257608	Genentech, Inc.	Non-Small Cell Lung Cancer	January 2006	Phase 3
NCT01069627	Hoffmann-La Roche	Malignant Melanoma	December 2006	Phase 2
NCT00328497	CASI Pharmaceuticals, Inc.	Carcinoid Tumor	May 2006	Phase 2
NCT00681603	National Taiwan University Hospital	Lipid Keratopathy\|Penetrating Keratoplasty\|Herpetic Keratopathy\|Rosacea	August 2007	Not Applicable
NCT01327612	Amgen	Advanced Solid Tumors\|Carcinoid\|Colorectal Cancer\|Locally Advanced\|Lymphoma\|Metastatic Cancer\|Non-Small Cell Lung Cancer\|Sarcoma\|Solid Tumors	March 3, 2011	Phase 2
NCT00423917	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Breast Cancer	August 2007	Phase 2
NCT00444041	Austrian Society Of Surgical Oncology	Metastatic Colorectal Cancer	January 2007	Phase 1\|Phase 2
NCT00545792	Dana-Farber Cancer Institute\|Genentech, Inc.\|Brigham and Women´s Hospital\|Beth Israel Deaconess Medical Center\|Massachusetts General Hospital\|Lowell General Hospital\|Saint Anne´s Hospital	Cervical Cancer\|Endometrial Cancer\|Ovarian Cancer\|Vaginal Cancer\|Carcinoma of the Vulva	May 2007	Phase 2
NCT02839707	National Cancer Institute (NCI)\|NRG Oncology	Fallopian Tube High Grade Serous Adenocarcinoma\|Ovarian High Grade Serous Adenocarcinoma\|Ovarian Seromucinous Carcinoma\|Primary Peritoneal High Grade Serous Adenocarcinoma\|Recurrent Fallopian Tube Carcinoma\|Recurrent Fallopian Tube Clear Cell Adenocarcinoma\|Recurrent Fallopian Tube Endometrioid Adenocarcinoma\|Recurrent Fallopian Tube Undifferentiated Carcinoma\|Recurrent Ovarian Carcinoma\|Recurrent Ovarian Clear Cell Adenocarcinoma\|Recurrent Ovarian Endometrioid Adenocarcinoma\|Recurrent Ovarian Undifferentiated Carcinoma\|Recurrent Platinum-Resistant Fallopian Tube Carcinoma\|Recurrent Platinum-Resistant Ovarian Carcinoma\|Recurrent Platinum-Resistant Primary Peritoneal Carcinoma\|Recurrent Primary Peritoneal Carcinoma\|Recurrent Primary Peritoneal Clear Cell Adenocarcinoma\|Recurrent Primary Peritoneal Endometrioid Adenocarcinoma\|Recurrent Primary Peritoneal Undifferentiated Carcinoma	May 12, 2017	Phase 2\|Phase 3
NCT01632228	Hoffmann-La Roche	Glioblastoma	June 29, 2012	Phase 2
NCT01767792	University of Alabama at Birmingham\|Genentech, Inc.	Neurofibromatosis Type 2\|Progressive Vestibular Schwannomas	May 15, 2013	Phase 2
NCT00268359	Duke University\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors	May 2005	Phase 2
NCT05009082	AGO Study Group\|European Network of Gynaecological Oncological Trial Groups (ENGOT)	Ovarian Cancer\|Fallopian Tube Cancer\|Peritoneal Cancer	September 13, 2022	Phase 3
NCT04426825	Hoffmann-La Roche	Carcinoma, Non-Small-Cell Lung	September 9, 2020	Phase 2
NCT03093155	Yale University\|R-Pharm-US, LLC	Epithelial Ovarian Cancer\|Fallopian Tube Cancer\|Primary Peritoneal Cancer	April 3, 2017	Phase 2
NCT04633564	Mylan Pharmaceuticals Inc\|Viatris Inc.	NSCLC Stage IV	January 21, 2017	Phase 3
NCT00614653	M.D. Anderson Cancer Center\|Genentech, Inc.	Pancreatic Cancer	January 2008	Phase 1
NCT00734890	National Institutes of Health Clinical Center (CC)\|National Cancer Institute (NCI)	Lung Cancer\|Lymphoma\|Lymphoproliferative Disorder\|Small Intestine Cancer\|Unspecified Adult Solid Tumor, Protocol Specific	March 2008	Phase 1
NCT02343549	Wake Forest University Health Sciences\|NovoCure Ltd.	Cancer of Brain and Nervous System	January 2015	Phase 2
NCT01146795	Jason D. Wright\|Genentech, Inc.\|Columbia University	Epithelial Ovarian Cancer\|Primary Peritoneal Cancer\|Fallopian Tube Cancer	May 17, 2010	Phase 2
NCT00161291	University of Alabama at Birmingham\|Genentech, Inc.	Breast Cancer	June 2005	Phase 2
NCT04456699	Merck Sharp & Dohme LLC	Metastatic Colorectal Cancer	August 19, 2020	Phase 3
NCT03196986	Beijing Mabworks Biotech Co., Ltd.\|Betta Pharmaceuticals Co., Ltd.	Non-small Cell Lung Cancer	August 15, 2017	Phase 3
NCT00222729	University of Pittsburgh\|Eli Lilly and Company\|Genentech, Inc.	Cancer	November 2005	Phase 2
NCT01940887	Ophthotech Corporation\|IVERIC bio, Inc.	Age-Related Macular Degeneration	May 2014	Phase 3
NCT02759588	Genelux Corporation	Ovarian Cancer\|Peritoneal Carcinomatosis\|Fallopian Tube Cancer	May 2016	Phase 1\|Phase 2
NCT00710229	The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery\|Krankenanstalt Rudolfstiftung\|Medical University of Vienna\|Medical University of Graz\|Medical University Innsbruck\|Krankenhaus der Barmherzigen Brüder Linz\|Universitätsaugenklinik Salzburg\|Hospital Hietzing\|Hanuschkrankenhaus	Age Related Macular Degeneration	July 2008	Phase 3
NCT00028834	National Cancer Institute (NCI)	Adenocarcinoma of the Pancreas\|Recurrent Pancreatic Cancer\|Stage III Pancreatic Cancer\|Stage IV Pancreatic Cancer	February 2002	Phase 2
NCT00016107	National Cancer Institute (NCI)	Adenocarcinoma of the Prostate\|Hormone-resistant Prostate Cancer\|Recurrent Prostate Cancer\|Stage IV Prostate Cancer	June 2001	Phase 2
NCT01777412	Johns Hopkins University\|Genentech, Inc.\|Guthy Jackson Charitable Foundation	Neuromyelitis Optica\|Neuromyelitis Optica Spectrum Disorder	June 2013	Phase 1
NCT00334763	Northwestern University\|National Cancer Institute (NCI)	Lung Cancer	May 2006	Phase 2
NCT01462890	AGO Study Group\|ARCAGY+ GINECO GROUP\|Nordic Society of Gynaecological Oncology - Clinical Trials Unit	Genital Diseases, Female\|Ovarian Diseases\|Ovarian Neoplasms\|Fallopian Tube Neoplasms\|Peritoneal Neoplasms	November 2011	Phase 3
NCT00615056	Pfizer	Colorectal Neoplasms	March 2008	Phase 2
NCT01046279	University of Zurich	Glioma Patients	January 2010
NCT00592176	University of Alabama at Birmingham	Pterygium	August 2007	Phase 2
NCT00403403	Genentech, Inc.	Small Cell Lung Cancer	March 2007	Phase 2
NCT00428922	Bhuvaneswari Ramaswamy\|Genentech, Inc.\|Case Comprehensive Cancer Center\|University of Pittsburgh\|Ohio State University Comprehensive Cancer Center	Breast Cancer	June 14, 2007	Phase 2
NCT05396937	Fudan University\|Roche Pharma AG	Hepatocellular Carcinoma	January 12, 2022	Phase 2
NCT05075993	M.D. Anderson Cancer Center\|Lyvgen Biopharma Holdings Limited	Metastatic Esophageal\|Gastric Cancer\|Metastatic Head and Neck Carcinoma\|Metastatic Hepatocellular Carcinoma\|Metastatic HPV Related Solid Tumors\|Metastatic Ovarian Carcinoma\|Metastatic Soft Tissue Sarcoma\|Metastatic Uveal Melanoma	November 12, 2021	Phase 1
NCT01133990	Eisai Inc.\|PharmaBio Development Inc.	Colorectal Cancer	April 2010	Phase 1\|Phase 2
NCT05146687	Novartis Pharmaceuticals\|Novartis	Age-related Macular Degeneration (AMD)	July 15, 2020
NCT00786643	Accelerated Community Oncology Research Network\|InterMune	Colorectal Cancer	February 2006	Phase 2
NCT04215731	Yanhong Deng\|Sun Yat-sen University	Rectal Cancer	March 27, 2020	Phase 3
NCT04217954	Peking University	Advanced Biliary Tract Cancer	July 28, 2020	Phase 2
NCT01332929	Centre Francois Baclesse\|National Cancer Institute, France\|Roche Pharma AG\|Institut Curie	Metastatic Malignant Neoplasm to Brain	June 2010	Phase 1
NCT00517361	University of Chicago\|Genentech, Inc.	Metastatic Breast Cancer	August 2007	Phase 2
NCT01338558	Hoffmann-La Roche	Colorectal Cancer	June 2011	Phase 3
NCT00846612	NYU Langone Health\|Genentech, Inc.\|University of New Mexico Cancer Center	Ovarian Cancer	January 2008	Phase 1
NCT00394433	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital\|Genentech, Inc.	Esophageal Cancer\|Stomach Cancer	September 2006	Phase 2
NCT00960960	Genentech, Inc.	Breast Cancer	August 2009	Phase 1
NCT04952753	Novartis Pharmaceuticals\|Novartis	Metastatic Colorectal Cancer	November 15, 2021	Phase 2
NCT00578149	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital	Non-Small Cell Lung Cancer	May 2006	Phase 2
NCT05039801	M.D. Anderson Cancer Center	Advanced Endometrial Carcinoma\|Advanced Head and Neck Squamous Cell Carcinoma\|Advanced Malignant Solid Neoplasm\|Advanced Melanoma\|Advanced Ovarian Clear Cell Adenocarcinoma\|Chondrosarcoma\|Clinical Stage III Cutaneous Melanoma AJCC v8\|Clinical Stage IV Cutaneous Melanoma AJCC v8\|Pathologic Stage III Cutaneous Melanoma AJCC v8\|Pathologic Stage IIIA Cutaneous Melanoma AJCC v8\|Pathologic Stage IIIB Cutaneous Melanoma AJCC v8\|Pathologic Stage IIIC Cutaneous Melanoma AJCC v8\|Pathologic Stage IIID Cutaneous Melanoma AJCC v8\|Pathologic Stage IV Cutaneous Melanoma AJCC v8\|Refractory Endometrial Carcinoma\|Refractory Head and Neck Squamous Cell Carcinoma\|Refractory High Grade Ovarian Serous Adenocarcinoma\|Refractory Melanoma\|Refractory Ovarian Clear Cell Adenocarcinoma\|Stage III Ovarian Cancer AJCC v8\|Stage III Uterine Corpus Cancer AJCC v8\|Stage IIIA Ovarian Cancer AJCC v8\|Stage IIIA Uterine Corpus Cancer AJCC v8\|Stage IIIA1 Ovarian Cancer AJCC v8\|Stage IIIA2 Ovarian Cancer AJCC v8\|Stage IIIB Ovarian Cancer AJCC v8\|Stage IIIB Uterine Corpus Cancer AJCC v8\|Stage IIIC Ovarian Cancer AJCC v8\|Stage IIIC Uterine Corpus Cancer AJCC v8\|Stage IIIC1 Uterine Corpus Cancer AJCC v8\|Stage IIIC2 Uterine Corpus Cancer AJCC v8\|Stage IV Ovarian Cancer AJCC v8\|Stage IV Uterine Corpus Cancer AJCC v8\|Stage IVA Ovarian Cancer AJCC v8\|Stage IVA Uterine Corpus Cancer AJCC v8\|Stage IVB Ovarian Cancer AJCC v8\|Stage IVB Uterine Corpus Cancer AJCC v8	September 9, 2021	Phase 1
NCT00391144	University of Trieste	Choroidal Neovascularization Secondary to Pattern Dystrophy	July 2006	Phase 2\|Phase 3
NCT01514123	Circadian Technologies Ltd.	Neoplasms\|Cancer	December 29, 2011	Phase 1
NCT01582152	M.D. Anderson Cancer Center\|Cortice Biosciences, Inc.	Brain Neoplasms\|Central Nervous System Neoplasms	July 2012	Phase 1\|Phase 2
NCT00312728	Genentech, Inc.	Non-Small Cell Lung Cancer\|Brain Neoplasms	March 2006	Phase 2
NCT01759238	Universitätsklinikum Hamburg-Eppendorf	Colorectal Cancer\|Metastases	May 2013	Phase 2
NCT00797485	Southern Italy Cooperative Oncology Group\|National Cancer Institute (NCI)	Colorectal Cancer	July 2008	Phase 3
NCT04446793	Cardiff Oncology	Metastatic Colorectal Cancer\|KRAS Gene Mutation
NCT00851045	Bristol-Myers Squibb	Colorectal Cancer (CRC)	October 2009	Phase 2
NCT01403610	The University of Texas Health Science Center at San Antonio	HIGH GRADE GLIOMA	June 2011	Phase 2
NCT00130728	Genentech, Inc.	Non-Small Cell Lung Cancer	June 8, 2005	Phase 3
NCT02802098	Centro Nacional de Investigaciones Oncologicas CARLOS III\|Fundacion CRIS de Investigación para Vencer el Cáncer	Metastatic Breast Cancer\|Bevacizumab-alone Maintenance Treatment Progression	May 2016	Early Phase 1
NCT00881504	Georgetown University\|Sanofi	Biliary Tract Cancer	June 2009	Phase 2
NCT01169558	Hoffmann-La Roche	Colorectal Cancer	May 2006	Phase 3
NCT00066846	National Cancer Institute (NCI)	Colorectal Cancer	August 2003	Phase 2
NCT00309998	University of Rochester	Lung Cancer	September 2005	Phase 2
NCT00607113	M.D. Anderson Cancer Center\|Novartis\|Genentech, Inc.	Neuroendocrine Carcinoma	January 2008	Phase 2
NCT00089609	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Prostatic Neoplasms	April 19, 2005	Phase 2
NCT02023710	Peking University Cancer Hospital & Institute	Melanoma	December 2013	Phase 2
NCT01735071	Mario Negri Institute for Pharmacological Research\|PharmaMar\|Hoffmann-La Roche	Ovarian Epithelial Cancer Recurrent	July 2013	Phase 2
NCT03424005	Hoffmann-La Roche\|Seagen Inc.\|Gilead Sciences	Triple Negative Breast Cancer	April 2, 2018	Phase 1\|Phase 2
NCT00127920	Gynecologic Oncology Associates\|Genentech, Inc.	Ovarian Neoplasms	August 2004	Phase 2
NCT01063010	Beth Israel Deaconess Medical Center\|The Cooper Health System\|Carolinas Medical Center	Septic Shock	February 2010	Not Applicable
NCT01700400	Cancer Research and Biostatistics Clinical Trials Consortium\|University of Arizona\|Providence Cancer Center, Earle A. Chiles Research Institute\|Novartis Pharmaceuticals	Non Small Cell Lung Cancer	September 2012	Phase 1
NCT00203905	University of Chicago	Head and Neck Cancer	January 2004	Phase 2
NCT02946359	Chinese PLA General Hospital	Lung Adenocarcinoma Metastatic	July 2016	Phase 2
NCT01290939	European Organisation for Research and Treatment of Cancer - EORTC\|Hoffmann-La Roche	Glioblastoma Multiforme\|Cognition Disorders\|Disability Evaluation	October 2011	Phase 3
NCT00667342	St. Jude Children´s Research Hospital\|Genentech, Inc.	Osteosarcoma\|Malignant Fibrous Histiocytoma (MFH) of Bone	June 3, 2008	Phase 2
NCT00055237	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Kaposi´s Sarcoma\|HIV Infections\|HIV Seronegativity	February 26, 2003	Phase 2
NCT00557713	Associacio catalana per a la recerca oncologica i les seves implicacions sanitaries i socials\|Hoffmann-La Roche	Rectal Neoplasms\|Locally Advanced Rectal Adenocarcinoma	February 2007	Phase 2
NCT00203502	University of Arkansas\|Genentech, Inc.	Breast Cancer	September 2005	Phase 2
NCT00537173	Hoosier Cancer Research Network\|United States Department of Defense\|Indiana University School of Medicine\|University of Colorado, Denver\|Baylor University\|McGill University	Breast Cancer	September 2007
NCT01113476	M.D. Anderson Cancer Center	Advanced Cancer	April 27, 2010	Phase 1
NCT01418222	Genentech, Inc.\|SCRI Development Innovations, LLC	Colorectal Cancer	September 14, 2011	Phase 2
NCT01770171	Catholic University of the Sacred Heart	Stage III-IV or Recurrent Endometrial Cancer	April 2012	Phase 2
NCT00948675	Eli Lilly and Company	Advanced Non-Small Cell Lung Cancer	September 1, 2009	Phase 3
NCT00920868	Herbert Hurwitz, MD\|Bristol-Myers Squibb\|Duke University	Solid Tumor\|Metastatic Colorectal Cancer	May 2009	Phase 1
NCT00945139	New Mexico Cancer Care Alliance\|Genentech, Inc.\|NYU Langone Health	Ovarian Cancer	March 2007	Phase 2
NCT05407155	Fudan University	Non-small Cell Lung Cancer Metastatic	June 2022	Not Applicable
NCT02761070	Kyorin University\|Japan Clinical Oncology Group	Glioblastoma\|Recurrence\|Progression	July 11, 2016	Phase 3
NCT04097444	Chugai Pharmaceutical	Metastatic Colorectal Cancer	October 11, 2019	Phase 2
NCT00365391	National Cancer Institute (NCI)	Adult Primary Hepatocellular Carcinoma\|Advanced Adult Primary Liver Cancer\|Localized Unresectable Adult Primary Liver Cancer\|Recurrent Adult Primary Liver Cancer	August 2006	Phase 2
NCT02866903	Hospices Civils de Lyon	Peritoneal Carcinosis	May 18, 2017	Phase 1\|Phase 2
NCT00351039	H. Lee Moffitt Cancer Center and Research Institute\|Genentech, Inc.\|Eli Lilly and Company	Non-Small Cell Lung Cancer	July 2006	Phase 1\|Phase 2
NCT04405674	Shanghai Chest Hospital	Non Small Cell Lung Cancer	July 15, 2020	Phase 2
NCT00710268	AstraZeneca	Neoplasm Metastasis	June 2008	Phase 1
NCT01274624	Oncolytics Biotech\|Montefiore Medical Center	KRAS Mutant Metastatic Colorectal Cancer	December 2010	Phase 1
NCT02705274	Marashi Eye Clinic	Proliferative Diabetic Retinopathy	February 2016	Phase 2\|Phase 3
NCT00735306	Duke University\|Genentech, Inc.	Pancreatic Cancer	July 2008	Phase 1
NCT00130780	Memorial Sloan Kettering Cancer Center	Carcinoma, Non-Small-Cell Lung	August 2005	Phase 2
NCT00345163	Genentech, Inc.	Glioblastoma	July 2006	Phase 2
NCT02022917	Chang Gung Memorial Hospital\|Hoffmann-La Roche\|Asian Gynecologic Oncology Group\|Taiwanese Gynecolgic Oncology Group	Epithelial Ovarian Cancer	March 2014	Phase 2
NCT00861705	National Cancer Institute (NCI)	Male Breast Carcinoma\|Stage IIA Breast Cancer AJCC v6 and v7\|Stage IIB Breast Cancer AJCC v6 and v7\|Stage IIIA Breast Cancer AJCC v7\|Triple-Negative Breast Carcinoma	May 15, 2009	Phase 2
NCT00027885	Case Comprehensive Cancer Center\|National Cancer Institute (NCI)	Breast Cancer	November 2001	Phase 2
NCT00977574	National Cancer Institute (NCI)\|NRG Oncology	Endometrial Adenocarcinoma\|Endometrial Adenosquamous Carcinoma\|Endometrial Clear Cell Adenocarcinoma\|Endometrial Serous Adenocarcinoma\|Recurrent Uterine Corpus Cancer\|Stage IIIA Uterine Corpus Cancer AJCC v7\|Stage IIIB Uterine Corpus Cancer AJCC v7\|Stage IIIC Uterine Corpus Cancer AJCC v7\|Stage IVA Uterine Corpus Cancer AJCC v7\|Stage IVB Uterine Corpus Cancer AJCC v7	September 14, 2009	Phase 2
NCT01443676	University of Zurich	Glioblastoma	October 2011	Phase 2
NCT00597506	Herbert Hurwitz\|Novartis Pharmaceuticals\|Genentech, Inc.\|Duke University	Colorectal Adenocarcinoma	October 2007	Phase 2
NCT05448677	University Hospital, Grenoble\|Genoscience Pharma	Hepatocellular Carcinoma	October 2022	Phase 2
NCT00826800	Memorial Sloan Kettering Cancer Center\|Genentech, Inc.	Colon Cancer	February 2009	Not Applicable
NCT01661790	Chinese PLA General Hospital\|Roche Pharma AG	Malignant Pleural Effusion	August 2009	Phase 3
NCT04944069	Second Affiliated Hospital of Nanchang University\|Jiangsu Hansoh Pharmaceutical Co., Ltd.	NSCLC\|Leptomeningeal Metastasis\|EGFR Activating Mutation	July 2021	Not Applicable
NCT00406380	Asociación para Evitar la Ceguera en México	Telangiectasis	September 2006	Phase 3
NCT01523314	King Saud University	Diabetic Macular Edema	March 2012	Phase 2\|Phase 3
NCT01298076	University of Sydney\|National Health and Medical Research Council, Australia	Diabetic Retinopathy\|Macular Edema	October 2010	Phase 2
NCT00811135	Hoffmann-La Roche	Breast Cancer	December 2008	Phase 2
NCT00640640	Sheba Medical Center\|Universitaire Ziekenhuizen KU Leuven	Neovascular Age Related Macular Degeneration	August 2007	Not Applicable
NCT00072046	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)\|NCIC Clinical Trials Group	Kidney Cancer	October 2003	Phase 3
NCT00874107	HiberCell, Inc.	Non-Small Cell Lung Cancer	June 2009	Phase 2
NCT00761644	M.D. Anderson Cancer Center	Advanced Cancer	August 21, 2008	Phase 1
NCT05310344	Lei Li\|Peking Union Medical College Hospital	Ovarian Carcinoma\|Platinum-resistant Ovarian Cancer\|Recurrent Ovarian Carcinoma\|Albumin-bound Paclitaxel\|Bevacizumab\|Survival Outcomes\|Adverse Events	March 27, 2022	Phase 2
NCT01217931	M.D. Anderson Cancer Center\|Novartis	Kidney Cancer	January 19, 2011	Phase 2
NCT02313272	H. Lee Moffitt Cancer Center and Research Institute\|Merck Sharp & Dohme LLC	Malignant Glioma	July 28, 2015	Phase 1
NCT00433381	National Cancer Institute (NCI)\|American College of Radiology Imaging Network\|Radiation Therapy Oncology Group	Adult Glioblastoma\|Adult Gliosarcoma\|Recurrent Adult Brain Neoplasm	March 1, 2007	Phase 2
NCT00421512	Memorial Sloan Kettering Cancer Center	Metastatic Renal Cell Carcinoma\|Kidney Cancer	March 2006	Phase 1
NCT00626561	M.D. Anderson Cancer Center\|Genentech, Inc.	Cervical Cancer\|Uterine Cancer	February 2008	Phase 2
NCT00780494	Pamela L. Kunz\|Genentech, Inc.\|Stanford University	Stomach Cancer\|Gastric (Stomach) Cancer\|Neoplasm of Cardioesophageal Junction\|Gastrointestinal Stromal Tumor (GIST)	February 2009	Phase 2
NCT00390156	University of California, San Francisco\|Novartis	Unspecified Adult Solid Tumor	August 2006	Phase 1
NCT00079430	National Cancer Institute (NCI)\|Gynecologic Oncology Group	Brenner Tumor\|Fallopian Tube Cancer\|Ovarian Clear Cell Cystadenocarcinoma\|Ovarian Endometrioid Adenocarcinoma\|Ovarian Mixed Epithelial Carcinoma\|Ovarian Mucinous Cystadenocarcinoma\|Ovarian Serous Cystadenocarcinoma\|Ovarian Undifferentiated Adenocarcinoma\|Primary Peritoneal Cavity Cancer\|Stage II Ovarian Epithelial Cancer\|Stage III Ovarian Epithelial Cancer\|Stage IV Ovarian Epithelial Cancer	June 2004	Phase 1
NCT03250832	Tesaro, Inc.\|GlaxoSmithKline	Neoplasms	August 8, 2017	Phase 1
NCT04634578	Jaeb Center for Health Research\|Pediatric Eye Disease Investigator Group\|National Eye Institute (NEI)	Retinopathy of Prematurity	May 18, 2022	Phase 2
NCT00501891	Duke University\|Genentech, Inc.\|Schering-Plough	Glioblastoma Multiforme	July 2007	Phase 2
NCT01047293	University of Utah\|Novartis	Colorectal Cancer	May 2010	Phase 1\|Phase 2
NCT01736449	Arrowhead Regional Medical Center	Pterygium	April 2011	Phase 4
NCT02308644	University of Sao Paulo	Diabetic Macular Edema	February 2009	Phase 3
NCT01746238	Massachusetts General Hospital	Sarcoma	March 2013	Phase 1
NCT01445509	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Solid Tumors	December 29, 2008	Phase 1
NCT00084604	National Cancer Institute (NCI)	Adenocarcinoma of the Gastroesophageal Junction\|Diffuse Adenocarcinoma of the Stomach\|Intestinal Adenocarcinoma of the Stomach\|Mixed Adenocarcinoma of the Stomach\|Recurrent Gastric Cancer\|Stage IIIA Gastric Cancer\|Stage IIIB Gastric Cancer\|Stage IIIC Gastric Cancer\|Stage IV Gastric Cancer	April 2004	Phase 2
NCT03744806	Medical University of Lublin	Exudative Age-related Macular Degeneration	January 2015
NCT01025934	University of Campania Luigi Vanvitelli\|Napoli CTO Hospital	Proliferative Diabetic Retinopathy		Phase 4
NCT03821168	Shahid Beheshti University of Medical Sciences	Refractory Diabetic Macular Edema	March 1, 2019	Phase 2\|Phase 3
NCT02387957	Ophthotech Corporation\|Ophthotech	Age-Related Macular Degeneration	April 26, 2016	Phase 2
NCT05525767	Hebei Medical University Fourth Hospital	Solid Tumor	March 31, 2022	Phase 4
NCT00097019	Genentech, Inc.	Ovarian Cancer	February 2005	Phase 2
NCT00343044	Benaroya Research Institute\|GlaxoSmithKline\|Genentech, Inc.	Ovarian Cancer\|Fallopian Tube Cancer\|Peritoneal Cancer	June 2006	Phase 2
NCT02934529	Ludwig-Maximilians - University of Munich	Metastatic Colorectal Cancer	March 2015	Phase 3
NCT01838538	Chinese PLA General Hospital	Ovarian Cancer With Malignant Ascites	June 2011	Phase 2
NCT00308529	SCRI Development Innovations, LLC\|Genentech, Inc.	Carcinoma, Small Cell Lung\|Lung Cancer	March 2006	Phase 2
NCT01811498	Northwell Health\|Feinstein Institute for Medical Research	Glioblastoma Multiforme\|Brain Tumor	February 2013	Phase 1\|Phase 2
NCT04227028	City of Hope Medical Center\|National Cancer Institute (NCI)	Locally Advanced Lung Non-Small Cell Carcinoma\|Metastatic Lung Non-Small Cell Carcinoma\|Recurrent Lung Non-Small Cell Carcinoma\|Stage III Lung Cancer AJCC v8\|Stage IIIA Lung Cancer AJCC v8\|Stage IIIB Lung Cancer AJCC v8\|Stage IIIC Lung Cancer AJCC v8\|Stage IV Lung Cancer AJCC v8\|Stage IVA Lung Cancer AJCC v8\|Stage IVB Lung Cancer AJCC v8	March 9, 2020	Phase 1
NCT00447031	Yonsei University	Macular Degeneration	March 2007	Not Applicable
NCT00908219	Baylor College of Medicine\|Genentech, Inc.	Malignant Ascites	July 2009	Phase 2
NCT00109239	Genentech, Inc.	Breast Cancer	November 2000	Phase 3
NCT04245865	Vejle Hospital	Colorectal Cancer Metastatic	June 26, 2020	Phase 2
NCT02661815	Dana-Farber Cancer Institute\|Celgene Corporation	Ovarian Cancer\|Fallopian Tube Cancer\|Primary Peritoneal Carcinoma	June 15, 2016	Phase 1
NCT00571142	Asociación para Evitar la Ceguera en México	* Diffuse Diabetic Macular Edema	November 2007	Phase 3
NCT00227019	Heather Wakelee\|Eli Lilly and Company\|Genentech, Inc.\|Stanford University	Non-small Cell Lung Cancer (NSCLC)\|Lung Cancer\|Neoplasm Metastasis	March 2006	Phase 2
NCT00953121	Annick Desjardins\|Duke University	Malignant Glioma	September 2009	Phase 2
NCT00865189	Hoffmann-La Roche	Rectal Cancer	October 23, 2007	Phase 2
NCT01712347	Hoffmann-La Roche	Colorectal Cancer	October 11, 2012
NCT01217398	Institut Curie\|National Cancer Institute (NCI)	Intraocular Melanoma	October 2009	Phase 2
NCT00997191	University of Sao Paulo\|Fundação de Amparo à Pesquisa do Estado de São Paulo	Diabetic Macular Edema	October 2009	Phase 3
NCT05083689	Shahid Beheshti University of Medical Sciences	Diabetic Macular Edema	October 6, 2021	Phase 2\|Phase 3
NCT02923739	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Fallopian Tube Adenocarcinoma\|Fallopian Tube Clear Cell Adenocarcinoma\|Fallopian Tube Endometrioid Adenocarcinoma\|Fallopian Tube Mucinous Adenocarcinoma\|Fallopian Tube Serous Adenocarcinoma\|Fallopian Tube Transitional Cell Carcinoma\|Fallopian Tube Undifferentiated Carcinoma\|Malignant Ovarian Brenner Tumor\|Ovarian Adenocarcinoma\|Ovarian Clear Cell Adenocarcinoma\|Ovarian Endometrioid Adenocarcinoma\|Ovarian Mucinous Adenocarcinoma\|Ovarian Seromucinous Carcinoma\|Ovarian Serous Adenocarcinoma\|Ovarian Transitional Cell Carcinoma\|Ovarian Undifferentiated Carcinoma\|Primary Peritoneal Serous Adenocarcinoma\|Recurrent Fallopian Tube Carcinoma\|Recurrent Ovarian Carcinoma\|Recurrent Primary Peritoneal Carcinoma	May 5, 2017	Phase 2
NCT00356122	Sanofi\|Genentech, Inc.	Non-Small Cell Lung Cancer	July 2006	Phase 2
NCT04147351	National Taiwan University Hospital	NSCLC Stage IIIB~IV	April 10, 2020	Phase 2
NCT00806169	Johann Wolfgang Goethe University Hospital	Macular Edema\|Diabetic Retinopathy	April 2006	Phase 3
NCT00531960	Hoffmann-La Roche	Non-Small Cell Lung Cancer	January 2008	Phase 2
NCT00887809	Memorial Sloan Kettering Cancer Center\|Genentech, Inc.	Sarcoma\|Leiomyosarcoma\|Malignant Fibrous\|Histiocytoma\|Angiosarcoma	April 2009	Phase 2
NCT00619268	Centre Leon Berard	Metastatic Renal Cell Carcinoma	February 2008	Phase 2
NCT00370370	Shahid Beheshti University of Medical Sciences	Neovascular Age-Related Macular Degeneration	November 2005	Phase 3
NCT00017394	National Cancer Institute (NCI)	Male Breast Cancer\|Recurrent Breast Cancer\|Stage IV Breast Cancer	March 2001	Phase 2
NCT05588388	Kamya Sankar\|Genentech, Inc.\|University of Michigan\|VA Ann Arbor Healthcare System\|Cedars-Sinai Medical Center	Extensive-stage Small-cell Lung Cancer\|Liver Metastases	February 1, 2023	Phase 2
NCT01205022	City of Hope Medical Center\|National Cancer Institute (NCI)	Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage IV Colon Cancer\|Stage IV Rectal Cancer	April 2011	Phase 1
NCT00043823	M.D. Anderson Cancer Center\|Genentech, Inc.\|Vanderbilt-Ingram Cancer Center	Lung Cancer	August 1, 2002	Phase 1\|Phase 2
NCT02348255	University of California, Davis\|National Cancer Institute (NCI)\|NovoCure Ltd.	Adult Brain Glioblastoma\|Recurrent Adult Brain Neoplasm	January 2016	Phase 2
NCT01189643	Memorial Sloan Kettering Cancer Center\|Genentech, Inc.	Sarcoma\|Desmoplastic Small Round Cell Tumor (DSRCT)	August 2010	Early Phase 1
NCT02162563	Dutch Colorectal Cancer Group	Colorectal Cancer\|Liver Metastases	July 2014	Phase 3
NCT03872661	Sun Yat-sen University	Lung Cancer Stage III	March 1, 2019	Phase 2
NCT02759614	Guangdong Association of Clinical Trials	NSCLC	April 1, 2016	Phase 3
NCT01270438	National Cancer Institute (NCI)	Adenocarcinoma of the Colon\|Adenocarcinoma of the Rectum\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer	December 2010	Phase 2
NCT03280563	Hoffmann-La Roche	Breast Neoplasms	December 26, 2017	Phase 1\|Phase 2
NCT04973293	Ruijin Hospital	Lung Neoplasm Malignant	July 20, 2021	Not Applicable
NCT00744718	Vejle Hospital	Ovarian Cancer	August 2008	Phase 2
NCT01405430	Centre Leon Berard\|UMR-S Inserm 1036	Colorectal Cancer\|Metastasis	May 2010	Not Applicable
NCT01331616	West Penn Allegheny Health System	Glioblastoma\|Optic Neuropathy	March 2011	Early Phase 1
NCT00393497	Indiana University School of Medicine\|Indiana University	Breast Cancer\|Lymphedema	April 2007	Phase 1
NCT02337491	Dana-Farber Cancer Institute	Glioblastoma	February 9, 2015	Phase 2
NCT00101348	National Cancer Institute (NCI)	Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma\|Recurrent Adenoid Cystic Carcinoma of the Oral Cavity\|Recurrent Basal Cell Carcinoma of the Lip\|Recurrent Colon Cancer\|Recurrent Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity\|Recurrent Inverted Papilloma of the Paranasal Sinus and Nasal Cavity\|Recurrent Lymphoepithelioma of the Nasopharynx\|Recurrent Lymphoepithelioma of the Oropharynx\|Recurrent Metastatic Squamous Neck Cancer With Occult Primary\|Recurrent Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity\|Recurrent Mucoepidermoid Carcinoma of the Oral Cavity\|Recurrent Non-small Cell Lung Cancer\|Recurrent Pancreatic Cancer\|Recurrent Rectal Cancer\|Recurrent Salivary Gland Cancer\|Recurrent Squamous Cell Carcinoma of the Hypopharynx\|Recurrent Squamous Cell Carcinoma of the Larynx\|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity\|Recurrent Squamous Cell Carcinoma of the Nasopharynx\|Recurrent Squamous Cell Carcinoma of the Oropharynx\|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity\|Recurrent Verrucous Carcinoma of the Larynx\|Recurrent Verrucous Carcinoma of the Oral Cavity\|Stage III Adenoid Cystic Carcinoma of the Oral Cavity\|Stage III Basal Cell Carcinoma of the Lip\|Stage III Colon Cancer\|Stage III Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity\|Stage III Inverted Papilloma of the Paranasal Sinus and Nasal Cavity\|Stage III Lymphoepithelioma of the Nasopharynx\|Stage III Lymphoepithelioma of the Oropharynx\|Stage III Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity\|Stage III Mucoepidermoid Carcinoma of the Oral Cavity\|Stage III Pancreatic Cancer\|Stage III Rectal Cancer\|Stage III Salivary Gland Cancer\|Stage III Squamous Cell Carcinoma of the Hypopharynx\|Stage III Squamous Cell Carcinoma of the Larynx\|Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity\|Stage III Squamous Cell Carcinoma of the Nasopharynx\|Stage III Squamous Cell Carcinoma of the Oropharynx\|Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity\|Stage III Verrucous Carcinoma of the Larynx\|Stage III Verrucous Carcinoma of the Oral Cavity\|Stage IIIB Non-small Cell Lung Cancer\|Stage IV Adenoid Cystic Carcinoma of the Oral Cavity\|Stage IV Basal Cell Carcinoma of the Lip\|Stage IV Colon Cancer\|Stage IV Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity\|Stage IV Inverted Papilloma of the Paranasal Sinus and Nasal Cavity\|Stage IV Lymphoepithelioma of the Nasopharynx\|Stage IV Lymphoepithelioma of the Oropharynx\|Stage IV Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity\|Stage IV Mucoepidermoid Carcinoma of the Oral Cavity\|Stage IV Non-small Cell Lung Cancer\|Stage IV Pancreatic Cancer\|Stage IV Rectal Cancer\|Stage IV Renal Cell Cancer\|Stage IV Salivary Gland Cancer\|Stage IV Squamous Cell Carcinoma of the Hypopharynx\|Stage IV Squamous Cell Carcinoma of the Larynx\|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity\|Stage IV Squamous Cell Carcinoma of the Nasopharynx\|Stage IV Squamous Cell Carcinoma of the Oropharynx\|Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity\|Stage IV Verrucous Carcinoma of the Larynx\|Stage IV Verrucous Carcinoma of the Oral Cavity\|Untreated Metastatic Squamous Neck Cancer With Occult Primary	January 2005	Phase 1\|Phase 2
NCT00571740	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Colorectal Cancer		Phase 2
NCT02399592	Vejle Hospital	Ovarian Cancer	March 2015	Phase 2
NCT04138992	Air Force Military Medical University, China	Disease Free Survival	August 1, 2020	Phase 2\|Phase 3
NCT04984980	Fudan University	Biliary Tract Carcinoma\|Initially Unresectable	August 1, 2020	Phase 2
NCT02530801	University of Nottingham	Recurrent Pterygium	January 2017	Phase 4
NCT04074785	University of Texas Southwestern Medical Center	GBM\|Glioblastoma\|Brain Tumor\|Brain Tumor, Recurrent	December 13, 2019	Early Phase 1
NCT04238169	Xinqiao Hospital of Chongqing	Non-Small-Cell Lung Cancer Stage IV	September 1, 2020	Phase 2
NCT05299476	Chinese PLA General Hospital	Advanced Gastroesophageal Adenocarcinoma\|First-line Therapy\|PDL1 CPS < 5	April 16, 2022	Phase 2
NCT05200364	Sutro Biopharma, Inc.	Ovarian Cancer\|Ovarian Carcinoma\|Ovary Cancer\|Fallopian Tube Cancer\|Primary Peritoneal Carcinoma	March 22, 2022	Phase 1
NCT00873756	Genentech, Inc.	Metastatic Colorectal Cancer	May 2009	Phase 1
NCT05440578	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Ovarian Neoplasms	June 2022
NCT01860638	Hoffmann-La Roche	Glioblastoma	August 19, 2013	Phase 2
NCT00365417	NSABP Foundation Inc\|Genentech, Inc.\|Hoffmann-La Roche\|International Drug Development Institute	Breast Cancer	August 2006	Phase 2
NCT00596362	Memorial Sloan Kettering Cancer Center	Uveal Melanoma	April 2007	Not Applicable
NCT05231122	Roswell Park Cancer Institute\|National Cancer Institute (NCI)	Ovarian Clear Cell Adenocarcinoma\|Platinum-Sensitive Ovarian Carcinoma\|Recurrent Endometrial Serous Adenocarcinoma\|Recurrent Fallopian Tube Carcinoma\|Recurrent Fallopian Tube Endometrioid Adenocarcinoma\|Recurrent Fallopian Tube Serous Adenocarcinoma\|Recurrent Ovarian Carcinoma\|Recurrent Ovarian Clear Cell Adenocarcinoma\|Recurrent Ovarian Endometrioid Adenocarcinoma\|Recurrent Ovarian Serous Adenocarcinoma\|Recurrent Platinum-Resistant Ovarian Carcinoma\|Recurrent Primary Peritoneal Carcinoma\|Recurrent Primary Peritoneal Clear Cell Adenocarcinoma\|Recurrent Primary Peritoneal Endometrioid Adenocarcinoma\|Recurrent Primary Peritoneal Serous Adenocarcinoma	November 30, 2022	Phase 2
NCT01663727	Hoffmann-La Roche	Metastatic Breast Cancer	August 27, 2012	Phase 3
NCT03904563	Sun Yat-sen University	Lung Adenocarcinoma	January 1, 2019	Phase 2
NCT00776594	Dana-Farber Cancer Institute\|Genentech, Inc.\|Beth Israel Deaconess Medical Center\|Brigham and Women´s Hospital\|Rutgers Cancer Institute of New Jersey	Prostate Cancer	October 2008	Phase 2
NCT01730950	Radiation Therapy Oncology Group\|National Cancer Institute (NCI)	Adult Giant Cell Glioblastoma\|Adult Glioblastoma\|Adult Gliosarcoma\|Recurrent Adult Brain Tumor	December 20, 2012	Phase 2
NCT00586508	Eli Lilly and Company\|Genentech, Inc.	Recurrent Glioblastoma	November 2007	Phase 2
NCT00476827	Duke University\|Genentech, Inc.	Breast Cancer	May 2007	Phase 2
NCT00468351	University of Sao Paulo	Diabetic Macular Edema	April 2006	Phase 1
NCT05468359	St. Jude Children´s Research Hospital	Refractory Solid Tumor\|Hepatocellular Carcinoma\|Malignant Solid Tumor\|Pediatric Cancer\|Pediatric Solid Tumor	November 2022	Phase 1\|Phase 2
NCT00940303	Hoffmann-La Roche	Colorectal Cancer	June 2009	Phase 2
NCT04973904	Peking Union Medical College Hospital	Cervical Cancer	August 1, 2021	Phase 2
NCT00720356	Northwestern University\|M.D. Anderson Cancer Center	Brain and Central Nervous System Tumors	July 7, 2009	Phase 2
NCT00193492	SCRI Development Innovations, LLC\|Genentech, Inc.	Lymphoma, Follicular	September 2005	Phase 2
NCT00367601	Nasser Hanna, M.D.\|Genentech, Inc.\|Walther Cancer Institute\|Hoosier Cancer Research Network	Lung Cancer	August 2006	Phase 2
NCT00267696	Ohio State University Comprehensive Cancer Center\|Genentech, Inc.\|Eli Lilly and Company	Ovarian Cancer\|Fallopian Tube Cancer\|Peritoneal Cancer	November 2005	Phase 2
NCT00295503	University of Texas Southwestern Medical Center\|University of Chicago\|Columbia University\|Duke University	Mesothelioma	February 2006	Phase 2
NCT01201265	Hoffmann-La Roche	Breast Cancer	February 2011	Phase 2
NCT00287222	University of Arkansas\|Genentech, Inc.	Hepatocellular Carcinoma	February 2006	Phase 2
NCT00407121	Asociación para Evitar la Ceguera en México	Vogt Koyanagi Harada Disease\|Serpiginous Choroiditis\|Multifocal Choroiditis	August 2006	Phase 3
NCT00449163	University of Miami	Colorectal Cancer	March 1, 2006	Phase 2
NCT00095706	Translational Oncology Research International\|Genentech, Inc.	Breast Cancer	June 2003	Phase 1\|Phase 2
NCT00828009	ECOG-ACRIN Cancer Research Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Lung Cancer	December 22, 2010	Phase 2
NCT00845104	Fred Hutchinson Cancer Research Center+University of Washington Cancer Consortium\|Fred Hutchinson Cancer Center	B-cell Chronic Lymphocytic Leukemia\|Refractory Chronic Lymphocytic Leukemia	January 2009	Phase 2
NCT04659382	Federation Francophone de Cancerologie Digestive	Metastatic Colorectal Cancer\|pMMR\|MSS\|Immune Checkpoint Inhibitor\|Internal Radiotherapy	October 7, 2020	Phase 2
NCT00193154	SCRI Development Innovations, LLC\|AstraZeneca\|Genentech, Inc.	Kidney Cancer	February 2003	Phase 2
NCT00112840	National Cancer Institute (NCI)	Clear Cell Renal Cell Carcinoma\|Recurrent Renal Cell Cancer\|Stage IV Renal Cell Cancer	May 2005	Phase 1\|Phase 2
NCT00569699	Taiho Pharmaceutical Co., Ltd.	Colorectal Cancer	October 2007	Phase 2
NCT00506155	M.D. Anderson Cancer Center\|Genentech, Inc.	Bladder Cancer	June 2007	Phase 2
NCT00423059	Yonsei University	Diabetic Retinopathy	December 2006	Not Applicable
NCT03843853	The First Affiliated Hospital with Nanjing Medical University\|Jiangsu HanSoh Tharmaceutical Group Co., Ltd	Colorectal Neoplasms	May 1, 2019	Phase 2
NCT00504257	H. Lee Moffitt Cancer Center and Research Institute\|National Cancer Institute (NCI)\|Genentech, Inc.\|Sanofi	Fallopian Tube Cancer\|Ovarian Cancer\|Malignant Tumor of Peritoneum	March 2007	Phase 2
NCT00294931	SCRI Development Innovations, LLC\|Genentech, Inc.	Carcinoma, Small Cell Lung	February 2006	Phase 2
NCT00336648	M.D. Anderson Cancer Center\|Genentech, Inc.	Pancreatic Neoplasms	June 2006	Phase 2
NCT01131078	Hoffmann-La Roche	Colorectal Cancer	June 2005	Phase 2
NCT00318513	Premiere Oncology of Arizona\|Genentech, Inc.	Lymphedema		Phase 1
NCT01995188	Genentech, Inc.	Non-Squamous Non-Small Cell Lung Cancer	December 16, 2013	Phase 1
NCT04954339	Tae Won Kim\|Asan Medical Center	Hepatocellular Carcinoma	October 29, 2021	Phase 2
NCT00798603	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Lung Cancer	December 2008	Phase 2
NCT00394082	Celgene	Metastatic Breast Cancer	June 1, 2006	Phase 2
NCT01984242	Hoffmann-La Roche	Renal Cell Carcinoma	January 8, 2014	Phase 2
NCT03063762	Hoffmann-La Roche	Renal Cell Carcinoma	March 27, 2017	Phase 1
NCT01426074	Abramson Cancer Center of the University of Pennsylvania	Rectal Cancer Patients	August 2011	Phase 2
NCT01366131	Genentech, Inc.	Non-Squamous Non-Small Cell Lung Cancer	June 2011	Phase 2
NCT01439178	Seoul St. Mary´s Hospital	Complications of Diabetes Mellitus	August 2011	Not Applicable
NCT00424840	University of Massachusetts, Worcester\|Millennium Pharmaceuticals, Inc.\|Genentech, Inc.	Lung Cancer	June 2006	Phase 1
NCT00227617	University of California, San Francisco\|Genentech, Inc.\|Sanofi	Gastrointestinal Carcinoid Tumor\|Islet Cell Tumor\|Lung Cancer\|Neoplastic Syndrome\|Neuroendocrine Tumor	June 8, 2005	Phase 2\|Phase 3
NCT05445778	ImmunoGen, Inc.\|GOG Foundation	Ovarian Cancer\|Peritoneal Cancer\|Fallopian Tube Cancer	November 2022	Phase 3
NCT01474239	Hoffmann-La Roche	Glioblastoma Multiforme	November 2011	Phase 2
NCT02119026	Prof. Dr. Werner Scheithauer\|Medical University of Vienna	Metastatic Colorectal Cancer	February 2011	Phase 2
NCT04857684	Massachusetts General Hospital\|Genentech, Inc.	Hepatocellular Carcinoma\|Resectable Hepatocellular Carcinoma	June 18, 2021	Early Phase 1
NCT03847428	AstraZeneca	Hepatocellular Carcinoma	April 29, 2019	Phase 3
NCT05551208	Chongqing University Cancer Hospital	Ovarian Cancer	August 15, 2022	Phase 2
NCT02885753	Federation Francophone de Cancerologie Digestive	Colorectal Neoplasms	December 2016	Phase 3
NCT00486759	Hoffmann-La Roche\|Genentech, Inc.	B-cell Lymphoma	July 26, 2007	Phase 3
NCT00934440	University of Kansas Medical Center\|Celgene	Renal Cell Carcinoma	June 2009	Phase 1\|Phase 2
NCT04404881	Hanny Al-Samkari, MD\|Massachusetts General Hospital	Hereditary Hemorrhagic Telangiectasia	November 23, 2020	Phase 2
NCT00785291	National Cancer Institute (NCI)	Estrogen Receptor Negative\|Estrogen Receptor Positive\|HER2+Neu Negative\|HER2+Neu Positive\|Progesterone Receptor Negative\|Progesterone Receptor Positive\|Recurrent Breast Carcinoma\|Stage IIIC Breast Cancer AJCC v6\|Stage IV Breast Cancer AJCC v6 and v7	October 13, 2008	Phase 3
NCT05096715	Massachusetts General Hospital\|Genentech, Inc.	Unresectable Hepatocellular Carcinoma	January 2022	Phase 1
NCT00653939	Mateon Therapeutics	Tumors	March 2008	Phase 2
NCT05337137	Bristol-Myers Squibb	Carcinoma, Hepatocellular	May 5, 2022	Phase 1\|Phase 2
NCT01248949	MedImmune LLC	Advanced Solid Tumors\|Advanced Recurrent Ovarian Tumors	October 2010	Phase 1
NCT00567372	Asociación para Evitar la Ceguera en México	Diffuse Diabetic Macular Edema	June 2008	Phase 4
NCT00280150	UNC Lineberger Comprehensive Cancer Center\|Genentech, Inc.\|Eli Lilly and Company	Lung Cancer	January 2006	Phase 1\|Phase 2
NCT05468242	Sun Yat-sen University	Stage III Non-small Cell Lung Cancer	February 1, 2022	Phase 2
NCT05476341	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.	Rectal Cancer\|Lung Cancer\|Ovarian Cancer\|Cervical Cancer\|Glioblastoma	April 6, 2017	Phase 1
NCT04303988	Fudan University	Breast Cancer	March 30, 2020	Phase 2
NCT00308516	SCRI Development Innovations, LLC\|Genentech, Inc.	Rectal Cancer\|Cancer of the Rectum\|Colorectal Cancer	March 2006	Phase 2
NCT00193258	SCRI Development Innovations, LLC\|Genentech, Inc.\|Novartis	Clear Cell Renal Cell Carcinoma	June 2004	Phase 1\|Phase 2
NCT00756340	St. Jude Children´s Research Hospital\|Novartis Pharmaceuticals	Recurrent or Refractory Solid Tumors\|CNS Malignancies	July 2008	Phase 1
NCT02285959	Global Neurosciences Institute	Glioblastoma Multiforme	June 2014	Phase 1
NCT00851136	Genentech, Inc.	Metastatic Colorectal Cancer	May 2009	Phase 1
NCT00856492	Southwest Oncology Group\|National Cancer Institute (NCI)	Breast Cancer	April 2010	Phase 2
NCT00321100	Fox Chase Cancer Center	Colorectal Neoplasms	April 12, 2006	Phase 2
NCT00881751	Medical University of South Carolina	Liver Cancer	March 2009	Phase 2
NCT03368859	AbbVie	Cancer	March 20, 2018	Phase 2
NCT04862949	CHA University\|Hoffmann-La Roche	Advanced Hepatocellular Carcinoma	May 1, 2021
NCT00545870	Ursula Schmidt-Erfurth, M.D.\|Medical University of Vienna	Diabetic Retinopathy\|Diabetic Macular Edema\|Proliferative Diabetic Retinopathy	June 2008	Phase 3
NCT01814813	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)\|Agenus Inc.	Recurrent Glioblastoma\|Recurrent Adult Brain Tumor\|Gliosarcoma	May 2013	Phase 2
NCT02229175	University of California, San Francisco	Diabetic Macular Edema	January 1, 2021	Phase 2\|Phase 3
NCT02743923	The Netherlands Cancer Institute\|Dutch Society of Physicians for Pulmonology and Tuberculosis	Carcinoma, Non-Small Cell Lung	April 2016	Phase 3
NCT03074513	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Appendix Adenocarcinoma\|Human Papillomavirus-Related Anal Squamous Cell Carcinoma\|Human Papillomavirus-Related Cervical Squamous Cell Carcinoma\|Human Papillomavirus-Related Squamous Cell Carcinoma of the Penis\|Human Papillomavirus-Related Vulvar Squamous Cell Carcinoma\|Neuroendocrine Carcinoma\|Pancreatic Neuroendocrine Tumor\|Recurrent Merkel Cell Carcinoma\|Recurrent Nasopharynx Carcinoma\|Recurrent Peritoneal Malignant Mesothelioma\|Recurrent Pleural Malignant Mesothelioma\|Stage III Merkel Cell Carcinoma AJCC v7\|Stage III Nasopharyngeal Carcinoma AJCC v7\|Stage III Pleural Malignant Mesothelioma AJCC v7\|Stage IV Merkel Cell Carcinoma AJCC v7\|Stage IV Nasopharyngeal Carcinoma AJCC v7\|Stage IV Pleural Malignant Mesothelioma AJCC v7\|Stage IVA Nasopharyngeal Carcinoma AJCC v7\|Stage IVB Nasopharyngeal Carcinoma AJCC v7\|Stage IVC Nasopharyngeal Carcinoma AJCC v7\|Vaginal Squamous Cell Carcinoma, Not Otherwise Specified	March 3, 2017	Phase 2
NCT01933815	Cortice Biosciences, Inc.	Glioblastoma Multiforme	August 2013	Phase 1\|Phase 2
NCT04737187	Taiho Oncology, Inc.\|Institut de Recherches Internationales Servier	Refractory Metastatic Colorectal Cancer	November 25, 2020	Phase 3
NCT00976456	PD Dr. med. Wolfgang Schuette\|Roche Pharma AG\|Eli Lilly and Company\|Martha-Maria Krankenhaus Halle-Dölau gGmbH	Non-squamous Non-small Cell Lung Cancer	September 2009	Phase 3
NCT00960297	SCRI Development Innovations, LLC\|Genentech, Inc.	Non-Small Cell Lung Cancer	August 2009	Phase 2
NCT01167712	National Cancer Institute (NCI)\|NRG Oncology	Fallopian Tube Endometrioid Adenocarcinoma\|Fallopian Tube Mucinous Adenocarcinoma\|Fallopian Tube Transitional Cell Carcinoma\|Ovarian Brenner Tumor\|Ovarian Clear Cell Adenocarcinofibroma\|Ovarian Endometrioid Adenocarcinoma\|Ovarian Mucinous Adenocarcinoma\|Ovarian Seromucinous Carcinoma\|Ovarian Serous Adenocarcinoma\|Ovarian Transitional Cell Carcinoma\|Ovarian Undifferentiated Carcinoma\|Primary Peritoneal Serous Adenocarcinoma\|Stage IIA Fallopian Tube Cancer AJCC v6 and v7\|Stage IIA Ovarian Cancer AJCC V6 and v7\|Stage IIB Fallopian Tube Cancer AJCC v6 and v7\|Stage IIB Ovarian Cancer AJCC v6 and v7\|Stage IIC Fallopian Tube Cancer AJCC v6 and v7\|Stage IIC Ovarian Cancer AJCC v6 and v7\|Stage IIIA Fallopian Tube Cancer AJCC v7\|Stage IIIA Ovarian Cancer AJCC v6 and v7\|Stage IIIA Primary Peritoneal Cancer AJCC v7\|Stage IIIB Fallopian Tube Cancer AJCC v7\|Stage IIIB Ovarian Cancer AJCC v6 and v7\|Stage IIIB Primary Peritoneal Cancer AJCC v7\|Stage IIIC Fallopian Tube Cancer AJCC v7\|Stage IIIC Ovarian Cancer AJCC v6 and v7\|Stage IIIC Primary Peritoneal Cancer AJCC v7\|Stage IV Fallopian Tube Cancer AJCC v6 and v7\|Stage IV Ovarian Cancer AJCC v6 and v7\|Stage IV Primary Peritoneal Cancer AJCC v7	September 27, 2010	Phase 3
NCT04803994	Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest	Hepatocellular Carcinoma	July 6, 2021	Phase 3
NCT00049322	Jonsson Comprehensive Cancer Center\|National Cancer Institute (NCI)\|Genentech, Inc.	Liver Cancer	June 2003	Phase 2
NCT00110214	National Cancer Institute (NCI)	Adenocarcinoma of the Prostate\|Hormone-resistant Prostate Cancer\|Recurrent Prostate Cancer\|Stage IV Prostate Cancer	April 2005	Phase 3
NCT00612586	Eli Lilly and Company\|Roche Pharma AG	Colorectal Cancer	February 2008	Phase 2
NCT02162537	Centre Hospitalier Intercommunal Creteil\|Groupe Francais De Pneumo-Cancerologie	Non-small Cell Lung Cancer Metastatic\|Non-small Cell Lung Cancer\|Adenocarcinoma of Lung Metastatic to Brain\|Cerebral Metastases	December 2013	Phase 3
NCT00054132	National Cancer Institute (NCI)	Recurrent Breast Carcinoma\|Stage IV Breast Cancer	December 2002	Phase 2
NCT03511183	Harbin Medical University\|Cancer Institute and Hospital, Chinese Academy of Medical Sciences\|Fudan University\|Sun Yat-sen University\|First Affiliated Hospital of Harbin Medical University\|The Second Affiliated Hospital of Harbin Medical University\|Liaoning Tumor Hospital & Institute\|Shengjing Hospital\|The First Hospital of Jilin University\|The First Affiliated Hospital of Dalian Medical University\|Jilin Provincial Tumor Hospital\|The First People´s Hospital of Jingzhou	Colorectal Neoplasms\|Chemotherapy	March 1, 2018	Phase 2
NCT03211741	University Hospital, Ghent	Retinal Neovascularization\|Macular Edema	November 22, 2013	Phase 4
NCT00450827	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Neuroblastoma	August 2006	Phase 1
NCT05620771	Northwestern University\|National Cancer Institute (NCI)	Hepatocellular Carcinoma	November 25, 2022	Phase 2
NCT04102098	Hoffmann-La Roche	Carcinoma, Hepatocellular	December 31, 2019	Phase 3
NCT03401294	University of Saskatchewan	Metastatic Colorectal Cancer	January 1, 2023	Phase 2
NCT01572350	Hospital Universitario de Canarias	Diabetic Macular Edema	October 2010	Phase 3
NCT03334513	San Ni Chen\|Changhua Christian Hospital	Retinopathy of Prematurity	April 1, 2011
NCT05093608	H. Lee Moffitt Cancer Center and Research Institute\|Karyopharm Therapeutics Inc	Hepatocellular Carcinoma	November 3, 2021	Phase 1
NCT00462501	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)\|Genentech, Inc.	Colorectal Cancer	March 2007	Not Applicable
NCT05001880	National Cancer Institute (NCI)	Peritoneal Malignant Mesothelioma	October 15, 2021	Phase 2
NCT00425646	University of Washington\|National Cancer Institute (NCI)	Lung Cancer	November 2006	Phase 2
NCT02096874	King Khaled Eye Specialist Hospital	Non-proliferative Diabetic Retinopathy\|Proliferative Diabetic Retinopathy\|Diabetic Macular Edema	June 2013	Phase 4
NCT05507606	Tianjin Medical University Cancer Institute and Hospital	Non Small Cell Lung Cancer	August 1, 2021	Phase 2
NCT05431582	M.D. Anderson Cancer Center\|Zentalis Pharmaceuticals	Tumors\|Ovarian Cancer\|Breast Cancer\|Lung Cancer\|Pancreatic Cancer	December 30, 2022	Phase 1
NCT03532295	Washington University School of Medicine\|Incyte Corporation	Glioma\|Glioblastoma	April 20, 2020	Phase 2
NCT00819754	Ottawa Hospital Research Institute\|Hoffmann-La Roche\|Pfizer\|Sanofi\|Ottawa Regional Cancer Foundation	Metastatic Colorectal Cancer	November 2003	Phase 1\|Phase 2
NCT02819479	Norton Healthcare\|University of Kentucky	Radiation Necrosis	November 23, 2016	Phase 2
NCT01332604	Genentech, Inc.	Solid Cancers	July 2011	Phase 1
NCT03363867	Peter MacCallum Cancer Centre, Australia	Ovarian Cancer\|Fallopian Tube Cancer\|Primary Peritoneal Carcinoma	July 10, 2018	Phase 2
NCT02843230	Massachusetts General Hospital	Glioblastoma	August 1, 2016
NCT01219777	Ritu Salani\|Genentech, Inc.\|Ohio State University Comprehensive Cancer Center	Ovarian Cancer\|Primary Peritoneal Cancer\|Fallopian Tube Cancer	September 2010	Phase 1
NCT01339039	Patrick Y. Wen, MD\|Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital\|Genzyme, a Sanofi Company	High Grade Glioma: Glioblastoma (GBM)\|High Grade Glioma: Gliosarcoma\|Anaplastic Astrocytoma (AA)\|Anaplastic Oligodendroglioma (AO)\|Mixed Anaplastic Oligoastrocytoma (AOA)	December 2011	Phase 1
NCT02246049	EPS Corporation	Colorectal Neoplasms	May 2014	Phase 2
NCT01571232	Retina Macula Institute\|Allergan	Diabetic Macular Edema\|Non-proliferative Diabetic Retinopathy\|Proliferative Diabetic Retinopathy	April 2012	Phase 2
NCT04389073	Cancer Institute and Hospital, Chinese Academy of Medical Sciences\|Beijing Huanxing Cancer Hospital	Metastatic Breast Cancer	April 1, 2020	Phase 2
NCT04723004	Shanghai Junshi Bioscience Co., Ltd.	Advanced Hepatocellular Carcinoma (HCC)	October 15, 2020	Phase 3
NCT00405938	SCRI Development Innovations, LLC\|Genentech, Inc.\|AstraZeneca	Breast Cancer\|Breast Neoplasms	November 2006	Phase 2
NCT05378867	Zhejiang Teruisi Pharmaceutical Inc.	Metastatic Colorectal Cancer (CRC)	August 1, 2022	Phase 3
NCT02596958	Hoffmann-La Roche	Non-Squamous Non-Small Cell Lung Cancer	September 2007
NCT01270542	University of Southern California	Retinal Detachment\|Diabetic Retinopathy	June 2009	Not Applicable
NCT01239732	Hoffmann-La Roche	Ovarian Cancer	December 2010	Phase 3
NCT03937830	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Hepatocellular Cancer\|Hepatocellular Carcinoma\|Metastatic Hepatocellular Carcinoma	March 10, 2021	Phase 2
NCT02210117	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Clear Cell Renal Cell Carcinoma\|Metastatic Kidney Carcinoma\|Stage IV Renal Cell Cancer AJCC v7	November 25, 2014	Early Phase 1
NCT02036723	Biocad	Wet Age-related Macular Degeneration		Phase 3
NCT01063283	University of Chicago\|Genentech, Inc.	Advanced Non-squamous Non-Small Cell Lung Cancer	March 2010	Not Applicable
NCT00762255	H. Lee Moffitt Cancer Center and Research Institute\|Merck Sharp & Dohme LLC	Glioblastoma	September 2008	Phase 1
NCT00450203	Professor David Cunningham\|Cancer Research UK\|Roche Pharma AG\|GlaxoSmithKline\|Medical Research Council	Oesophagogastric Cancer	October 2007	Phase 2\|Phase 3
NCT01481545	National Cancer Institute, Naples	Rectal Cancer	December 2006	Phase 2
NCT03247673	Celltrion	Healthy	August 7, 2017	Phase 1
NCT00305877	National Cancer Institute (NCI)	Stage IA Pancreatic Cancer\|Stage IB Pancreatic Cancer\|Stage IIA Pancreatic Cancer\|Stage IIB Pancreatic Cancer	February 2006	Phase 2
NCT00463203	Rigshospitalet, Denmark	Brain Neoplasms\|Glioma	March 2007	Phase 2
NCT02052648	NewLink Genetics Corporation\|Lumos Pharma	Glioblastoma Multiforme\|Glioma\|Gliosarcoma\|Malignant Brain Tumor	March 2014	Phase 1\|Phase 2
NCT00324987	National Cancer Institute (NCI)	Gastrointestinal Stromal Tumor	April 2008	Phase 3
NCT00305825	University of California, San Francisco\|National Cancer Institute (NCI)\|Memorial Sloan Kettering Cancer Center	Breast Cancer	August 2004	Phase 2
NCT01774474	Maastricht University Medical Center\|European Society of Cataract and Refractive Surgeons	Cystoid Macular Edema\|Cataract\|Diabetes Mellitus	July 10, 2013	Phase 3
NCT00398320	Pamela L. Kunz\|Stanford University	Neuroendocrine Tumors	November 2006	Phase 2
NCT00428545	M.D. Anderson Cancer Center	Advanced Malignancy\|Lymphoma\|Myeloma\|Solid Tumors	January 2007	Phase 1
NCT00469469	Dartmouth-Hitchcock Medical Center\|Genentech, Inc.	Adrenocortical Carcinoma	May 2007	Phase 2
NCT00345761	Chugai Pharmaceutical\|Yakult Honsha Co., LTD	Colorectal Cancer	February 2006	Phase 1\|Phase 2
NCT00652119	Massachusetts General Hospital\|Genentech, Inc.\|National Cancer Institute (NCI)	Ovarian Cancer\|Peritoneal Cancer\|Fallopian Tube Cancer	February 2008	Phase 1
NCT01770301	ARCAGY+ GINECO GROUP\|Roche Pharma AG	Ovarian Sex-cord Stromal Tumor	February 2013	Phase 2
NCT00387699	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Lung Cancer	October 2006	Phase 2
NCT01031381	University of Pittsburgh\|Novartis Pharmaceuticals\|Genentech, Inc.	Ovarian Cancer\|Fallopian Tube Cancer\|Primary Peritoneal Carcinoma	September 2010	Phase 2
NCT02244632	Isofol Medical AB	Colorectal Neoplasm	September 2014	Phase 1\|Phase 2
NCT00846027	Hoffmann-La Roche	Breast Cancer	January 2009	Phase 2
NCT00661154	Stanford University\|Genentech, Inc.	Colorectal Neoplasms\|Colon Cancer\|Rectal Cancer\|Anal Cancer	February 2008
NCT00755261	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Sarcoma\|Soft Tissue Sarcoma	September 2008	Phase 2
NCT00925769	Hoffmann-La Roche	Pancreatic Cancer	January 2009	Phase 1
NCT01083966	Northwell Health\|Feinstein Institute for Medical Research\|Hofstra North Shore	Vestibular Schwannoma	August 2011	Phase 1
NCT00545077	Spanish Breast Cancer Research Group\|Hoffmann-La Roche\|German Breast Group	Breast Cancer	November 6, 2007	Phase 3
NCT02394795	Takeda	Colorectal Cancer	May 29, 2015	Phase 3
NCT03912402	Biocad	Cervical Cancer\|Cervical Cancer Metastatic\|Cervical Cancer Recurrent	December 25, 2018	Phase 2
NCT01836653	EPS Corporation	Liver Only Metastasis From KRAS Exon 2 Wild Type (Under Protocol 1.0-1.2 Edition) and RAS Wild Type (Under Protocol 2.0 Edition) Colorectal Cancer	May 2013	Phase 2
NCT01871766	St. Jude Children´s Research Hospital	Rhabdomyosarcoma	December 4, 2013	Phase 2
NCT02930954	Caicun Zhou\|Tongji University	Non-small-cell Lung Cancer	November 2016	Phase 2
NCT04733963	Second Affiliated Hospital, School of Medicine, Zhejiang University	Colorectal Cancer	March 1, 2021	Phase 2
NCT04042558	Centre Francois Baclesse\|GFPC	NSCLC Stage IIIB\|NSCLC Stage IV\|EGFR Gene Mutation\|ALK Gene Rearrangement Positive\|ROS1 Gene Mutation	September 26, 2019	Phase 2
NCT01202890	New Mexico Cancer Care Alliance\|Celgene Corporation	Ovarian Cancer\|Epithelial Ovarian Cancer\|Fallopian Tube Carcinoma\|Primary Peritoneal Carcinoma	September 2010	Phase 1
NCT00667394	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Glioblastoma\|Gliosarcoma\|Anaplastic Astrocytoma\|Anaplastic Oligodendroglioma\|Anaplastic Mixed Oligoastrocytoma	April 2008	Phase 2
NCT00568048	Swiss Group for Clinical Cancer Research	Melanoma (Skin)	December 2007	Phase 2
NCT00565851	National Cancer Institute (NCI)\|NRG Oncology	Clear Cell Adenocarcinoma\|Fallopian Tube Clear Cell Adenocarcinoma\|Fallopian Tube Endometrioid Adenocarcinoma\|Fallopian Tube Mucinous Adenocarcinoma\|Fallopian Tube Serous Adenocarcinoma\|Fallopian Tube Transitional Cell Carcinoma\|Fallopian Tube Undifferentiated Carcinoma\|Mucinous Adenocarcinoma\|Ovarian Brenner Tumor\|Ovarian Clear Cell Adenocarcinofibroma\|Ovarian Clear Cell Adenocarcinoma\|Ovarian Endometrioid Adenocarcinoma\|Ovarian Seromucinous Carcinoma\|Ovarian Serous Adenocarcinoma\|Ovarian Transitional Cell Carcinoma\|Ovarian Undifferentiated Carcinoma\|Primary Peritoneal Clear Cell Adenocarcinoma\|Primary Peritoneal Endometrioid Adenocarcinoma\|Primary Peritoneal Serous Adenocarcinoma\|Primary Peritoneal Transitional Cell Carcinoma\|Primary Peritoneal Undifferentiated Carcinoma\|Recurrent Fallopian Tube Carcinoma\|Recurrent Ovarian Carcinoma\|Recurrent Primary Peritoneal Carcinoma\|Undifferentiated Carcinoma	December 6, 2007	Phase 3
NCT02090322	Universidad Autonoma de San Luis Potosí	Retinopathy of Prematurity	September 2013	Not Applicable
NCT00626405	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Melanoma (Skin)	August 2008	Phase 2
NCT00576199	Hoffmann-La Roche	Liver Cancer	February 2008	Phase 2
NCT02833701	University of Nebraska\|National Cancer Institute (NCI)	Glioblastoma\|Glioma	March 2016	Phase 1
NCT01880385	Association Tunisienne de lutte Contre le Cancer\|Hoffmann-La Roche\|Sanofi	Inflammatory Breast Cancer	March 2011	Phase 1
NCT03597581	Inspirna, Inc.	Gastrointestinal Cancer\|Gastrointestinal Neoplasms\|Colorectal Cancer\|Colorectal Neoplasms\|Colorectal Carcinoma\|Gastric Cancer\|Gastric Neoplasm\|KRAS Mutation-Related Tumors\|CRC\|Colorectal Cancer Metastatic	June 5, 2018	Phase 1
NCT00795665	University of California, Davis\|National Cancer Institute (NCI)\|Genentech, Inc.	Glioma	June 2008	Phase 2
NCT02296567	East Florida Eye Institute\|Genentech, Inc.	Age Related Macular Degeneration	December 2014	Phase 2\|Phase 3
NCT03659305	R-Pharm\|Almedis	Healthy	July 10, 2018	Phase 1
NCT00368875	National Cancer Institute (NCI)	Male Breast Cancer\|Stage IIIB Breast Cancer\|Stage IIIC Breast Cancer\|Stage IV Breast Cancer	July 2006	Phase 1\|Phase 2
NCT00496587	M.D. Anderson Cancer Center\|Eli Lilly and Company	Renal Cell Carcinoma\|Kidney Cancer	July 2007	Phase 2
NCT05281471	Genelux Corporation\|GOG Foundation	Platinum-resistant Ovarian Cancer\|Platinum-refractory Ovarian Cancer\|Fallopian Tube Cancer\|Primary Peritoneal Cancer\|High-grade Serous Ovarian Cancer\|Endometrioid Ovarian Cancer\|Ovarian Clear Cell Carcinoma	August 31, 2022	Phase 3
NCT00308607	University of Turku	Metastatic Melanoma	August 2005	Phase 2
NCT00528567	Hoffmann-La Roche	Breast Cancer	December 2007	Phase 3
NCT05284643	University of Miami	Recurrent Glioblastoma	September 30, 2022	Not Applicable
NCT01279681	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)\|Cancer and Leukemia Group B	Cognitive+Functional Effects\|Colorectal Cancer\|Neurotoxicity	January 2011	Phase 3
NCT01057212	Providence Health & Services\|Genentech, Inc.\|Bristol-Myers Squibb	Non-squamous Non-small Cell Lung Cancer	February 2010	Phase 2
NCT00618826	Barbara Ann Karmanos Cancer Institute\|Eli Lilly and Company\|Genentech, Inc.	Metastatic Breast Cancer	November 2006	Phase 2
NCT00114946	Genentech, Inc.	Colorectal Cancer	May 2005	Phase 4
NCT02354131	Nordic Society of Gynaecological Oncology - Clinical Trials Unit\|European Network of Gynaecological Oncological Trial Groups (ENGOT)\|Gynecologic Cancer Intergroup (GCIG)\|University of Utah\|Massachusetts General Hospital\|Myriad Genetics, Inc.	Ovarian Cancer	February 15, 2015	Phase 1\|Phase 2
NCT03746041	University of Rochester	Myelodysplastic Syndromes\|Chronic Myelomonocytic Leukemia	February 14, 2019	Phase 1
NCT00408694	National Cancer Institute (NCI)\|Radiation Therapy Oncology Group	Stage II Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7\|Stage III Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7\|Stage III Nasopharyngeal Undifferentiated Carcinoma AJCC v7\|Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7\|Stage IV Nasopharyngeal Undifferentiated Carcinoma AJCC v7	December 13, 2006	Phase 2
NCT01149850	Jonsson Comprehensive Cancer Center\|Genentech, Inc.	Giant Cell Glioblastoma\|Glioblastoma\|Gliosarcoma	April 28, 2010	Phase 2
NCT02291289	Hoffmann-La Roche	Colorectal Cancer	April 17, 2015	Phase 2
NCT01222715	National Cancer Institute (NCI)	Adult Rhabdomyosarcoma\|Childhood Alveolar Rhabdomyosarcoma\|Childhood Pleomorphic Rhabdomyosarcoma\|Childhood Rhabdomyosarcoma With Mixed Embryonal and Alveolar Features\|Previously Treated Childhood Rhabdomyosarcoma\|Recurrent Adult Soft Tissue Sarcoma\|Recurrent Childhood Rhabdomyosarcoma	October 2010	Phase 2
NCT03203525	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Advanced Malignant Neoplasm\|Colorectal Carcinoma Metastatic in the Liver\|Metastatic Malignant Neoplasm in the Liver\|Refractory Malignant Neoplasm	June 23, 2020	Phase 1
NCT04180072	National Health Research Institutes, Taiwan\|National Taiwan University Hospital\|Taipei Veterans General Hospital, Taiwan\|Mackay Memorial Hospital\|Changhua Christian Hospital\|China Medical University Hospital\|National Cheng-Kung University Hospital\|Kaohsiung Medical University Chung-Ho Memorial Hospital\|Taichung Veterans General Hospital	Carcinoma, Hepatocellular	March 12, 2020	Not Applicable
NCT00410605	National Cancer Institute (NCI)	Multiple Myeloma in Relapse\|Stage II Multiple Myeloma\|Stage III Multiple Myeloma	November 2006	Phase 2
NCT00696592	University of Padova\|Department of Ophthalmology, Conegliano Hospital, Treviso, Italy	Neovascular Age-Related Macular Degeneration	January 2007	Phase 2
NCT01540435	University of Regensburg\|University of Halle Medical Faculty	Colon Cancer Liver Metastasis	September 2012	Phase 2
NCT02364713	Mayo Clinic\|National Cancer Institute (NCI)	Fallopian Tube Carcinosarcoma\|Fallopian Tube Clear Cell Adenocarcinoma\|Fallopian Tube Endometrioid Adenocarcinoma\|Fallopian Tube Mucinous Adenocarcinoma\|Fallopian Tube Serous Adenocarcinoma\|Fallopian Tube Transitional Cell Carcinoma\|Fallopian Tube Undifferentiated Carcinoma\|Ovarian Carcinosarcoma\|Ovarian Clear Cell Adenocarcinoma\|Ovarian Endometrioid Adenocarcinoma\|Ovarian Mucinous Adenocarcinoma\|Ovarian Seromucinous Carcinoma\|Ovarian Serous Adenocarcinoma\|Ovarian Transitional Cell Carcinoma\|Ovarian Undifferentiated Carcinoma\|Platinum-Resistant Fallopian Tube Carcinoma\|Platinum-Resistant Ovarian Carcinoma\|Platinum-Resistant Primary Peritoneal Carcinoma\|Primary Peritoneal Carcinosarcoma\|Primary Peritoneal Clear Cell Adenocarcinoma\|Primary Peritoneal Endometrioid Adenocarcinoma\|Primary Peritoneal Serous Adenocarcinoma\|Primary Peritoneal Transitional Cell Carcinoma\|Primary Peritoneal Undifferentiated Carcinoma\|Recurrent Fallopian Tube Carcinoma\|Recurrent Ovarian Carcinoma\|Recurrent Primary Peritoneal Carcinoma	March 13, 2015	Phase 2
NCT00738530	Hoffmann-La Roche	Renal Cell Cancer	June 2004	Phase 3
NCT00719264	Novartis Pharmaceuticals\|Roche Pharma AG\|Novartis	Carcinoma\|Adenocarcinoma\|Renal Cell\|Nephroid Carcinoma\|Hypernephroid	November 12, 2008	Phase 2
NCT01578551	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|National Cancer Institute (NCI)	Carcinoma, Non-Small-Cell Lung\|Lung Adenocarcinoma	May 2012	Phase 2
NCT02450981	Biocad	Neovascular Age-related Macular Degeneration		Phase 1
NCT04687631	Fudan University	Colorectal Cancer\|Liver Metastases	January 14, 2021	Phase 3
NCT02803203	Memorial Sloan Kettering Cancer Center\|AstraZeneca\|Genentech, Inc.	Non-small Cell Lung Cancer\|EGFR-mutant Lung Cancers	June 29, 2016	Phase 1\|Phase 2
NCT00544700	Swiss Group for Clinical Cancer Research	Colorectal Cancer	November 26, 2007	Phase 3
NCT00888043	Herbert Hurwitz, MD\|Centocor, Inc.\|Genentech, Inc.\|Duke University	Solid Tumors	March 2009	Phase 1
NCT03892434	Yeungnam University College of Medicine	Branch Retinal Vein Occlusion With Macular Edema	March 18, 2019	Phase 4
NCT00016549	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Breast Cancer	May 13, 2001	Phase 2
NCT01309633	National University Hospital, Singapore	Nasopharyngeal Carcinoma	September 2, 2011	Phase 2
NCT01200212	German Breast Group	Breast Cancer	July 2009	Phase 3
NCT04446416	NaviFUS Corporation\|Chang Gung Memorial Hospital	Glioblastoma Multiforme\|Glioblastoma\|Glioma\|Brain Tumor\|Neoplasms\|Neoplasms, Nerve Tissue	July 21, 2020	Not Applicable
NCT00184015	University of Southern California	Renal Cell Cancer	August 18, 2005	Phase 1\|Phase 2
NCT03326193	Tesaro, Inc.	Ovarian Neoplasms	December 12, 2017	Phase 2
NCT03126071	Jiangsu Cancer Institute & Hospital	Advanced Colorectal Cancer	February 15, 2017	Phase 2
NCT03288987	AryoGen Pharmed Co.	Metastatic Colorectal Cancer	October 4, 2016	Phase 3
NCT04250064	Tata Memorial Centre	DIPG	February 4, 2020	Phase 2
NCT01493843	Genentech, Inc.	Non-Small Cell Lung Cancer	January 20, 2012	Phase 2
NCT00911820	Dana-Farber Cancer Institute\|Massachusetts General Hospital\|SCRI Development Innovations, LLC\|Texas Oncology Cancer Center\|Genentech, Inc.	Esophageal Cancer\|Gastric Cancer\|Stomach Cancer	July 2009	Phase 2
NCT03798626	Novartis Pharmaceuticals\|Novartis	Colorectal Cancer\|Gastroesophageal Cancer\|Renal Cell Carcinoma	May 22, 2019	Phase 1
NCT00356681	Amgen	Breast Neoplasms\|Breast Tumors\|Breast Cancer\|Locally Recurrent and Metastatic Breast Cancer	December 2006	Phase 2
NCT03950154	Tianjin Medical University Cancer Institute and Hospital	Colorectal Cancer	June 1, 2019	Phase 3
NCT03175666	ImmunityBio, Inc.	Triple Negative Breast Cancer	December 2017	Phase 1\|Phase 2
NCT00605722	Hoffmann-La Roche	Liver Cancer	March 2008	Phase 2
NCT05266846	Hunan Province Tumor Hospital	ALK Gene Mutation\|Lung Adenocarcinoma\|Immunotherapy	September 20, 2022	Phase 2
NCT01127360	Oslo University Hospital	Exudative Age-related Macular Degeneration	March 2009	Phase 4
NCT01969708	The Emmes Company, LLC\|National Eye Institute (NEI)\|Milton S. Hershey Medical Center\|University of Wisconsin, Madison	Central Retinal Vein Occlusion	September 2014	Phase 3
NCT01718873	National Cancer Institute, Naples	Colorectal Cancer	May 2012	Phase 3
NCT02120287	Ajay Niranjan\|Genentech, Inc.\|University of Pittsburgh	Glioblastoma Multiforme\|Glioblastoma - Category	May 2014	Phase 2
NCT01609790	National Cancer Institute (NCI)\|NRG Oncology	Giant Cell Glioblastoma\|Glioblastoma\|Gliosarcoma\|Oligodendroglioma\|Recurrent Brain Neoplasm\|Recurrent Glioblastoma	June 4, 2012	Phase 2
NCT01368848	Arbeitsgemeinschaft medikamentoese Tumortherapie\|Sanofi\|Roche Pharma AG	NSCLC	April 2010	Phase 2
NCT00100841	National Cancer Institute (NCI)	Adenocarcinoma of the Rectum\|Mucinous Adenocarcinoma of the Colon\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Signet Ring Adenocarcinoma of the Colon\|Stage IV Colon Cancer\|Stage IV Rectal Cancer	November 2004	Phase 2
NCT00365547	Masonic Cancer Center, University of Minnesota	Lung Cancer	September 2006	Phase 2
NCT01283048	Toni Choueiri, MD\|Beth Israel Deaconess Medical Center\|Dana-Farber Cancer Institute	Renal Cell Carcinoma	September 2011	Phase 1
NCT01332721	Tracon Pharmaceuticals Inc.	Adult Solid Tumor	April 2011	Phase 1
NCT01250379	Hoffmann-La Roche	Breast Cancer	February 2011	Phase 3
NCT01531595	Pia Osterlund\|Helsinki University Central Hospital	Metastatic Colorectal Cancer	February 2012	Phase 2
NCT01086345	Case Comprehensive Cancer Center	Glioblastoma\|Gliosarcoma\|Brain Tumor	February 2010	Early Phase 1
NCT00193375	SCRI Development Innovations, LLC\|Genentech, Inc.\|Pharmacia and Upjohn	Lung Cancer	August 2003	Phase 2
NCT02065466	University of Arizona	Metastatic Melanoma\|Brain Metastases	July 2014	Phase 1\|Phase 2
NCT00998166	Columbia University	Non-Small Cell Lung Cancer	June 2007	Phase 2
NCT00434226	Genentech, Inc.	Non-Small Cell Lung Cancer	March 2007	Phase 2
NCT01989780	Japan Breast Cancer Research Group\|Chugai Pharmaceutical	Metastatic Breast Cancer	January 2014	Phase 2
NCT03169790	ImmunityBio, Inc.	Non Hodgkin Lymphoma	December 2017	Phase 1\|Phase 2
NCT00106054	Pfizer	Colorectal Neoplasms\|Liver Neoplasms	January 2006	Phase 2
NCT02884648	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Malignant Neoplasms of Female Genital Organs\|Ovarian Cancer\|Fallopian Tube Cancer\|Primary Peritoneal Cancer	November 2016	Phase 2
NCT00600340	Central European Cooperative Oncology Group	Metastatic Breast Cancer	April 2008	Phase 3
NCT03463265	Aadi Bioscience, Inc.	High Grade Recurrent Glioma and Newly Diagnosed Glioblastoma	August 1, 2018	Phase 2
NCT02672995	National Taiwan University Hospital	Brain Neoplasm	January 2018	Phase 1
NCT05005455	Innovent Biologics (Suzhou) Co. Ltd.	Healthy Male Subjects	July 30, 2021	Phase 1
NCT01802645	Technische Universität Dresden	Colorectal Cancer	March 2013	Phase 2
NCT02121990	Memorial Sloan Kettering Cancer Center\|AstraZeneca\|Genentech, Inc.	Ovarian Cancer\|Primary Peritoneal Cancer\|Fallopian Tube Cancer	April 21, 2014	Phase 1
NCT00268489	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Lung Cancer	May 2006	Phase 2
NCT00303628	ECOG-ACRIN Cancer Research Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Adenocarcinoma of the Rectum\|Stage II Rectal Cancer\|Stage III Rectal Cancer	February 17, 2006	Phase 3
NCT00559845	Hoffmann-La Roche	Breast Cancer	February 2008	Phase 2
NCT01208103	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Ampulla of Vater Adenocarcinoma\|Small Intestinal Adenocarcinoma\|Stage III Ampulla of Vater Cancer AJCC v8\|Stage III Small Intestinal Adenocarcinoma AJCC v8\|Stage IIIA Ampulla of Vater Cancer AJCC v8\|Stage IIIA Small Intestinal Adenocarcinoma AJCC v8\|Stage IIIB Ampulla of Vater Cancer AJCC v8\|Stage IIIB Small Intestinal Adenocarcinoma AJCC v8\|Stage IV Ampulla of Vater Cancer AJCC v8\|Stage IV Small Intestinal Adenocarcinoma AJCC v8	May 6, 2011	Phase 2
NCT01125046	Northwestern University	Acoustic Schwannoma\|Adult Anaplastic Meningioma\|Adult Ependymoma\|Adult Grade I Meningioma\|Adult Grade II Meningioma\|Adult Meningeal Hemangiopericytoma\|Adult Papillary Meningioma\|Neurofibromatosis Type 1\|Neurofibromatosis Type 2\|Recurrent Adult Brain Tumor	June 17, 2010	Phase 2
NCT03085992	Azienda Ospedaliero, Universitaria Pisana	Rectal Cancer	March 2012	Phase 2
NCT01020747	Massachusetts General Hospital	Recurrent Respiratory Papillomatosis	November 2009	Phase 1
NCT04813913	University Hospital, Rouen	Oncology	May 5, 2019	Phase 4
NCT00081861	M.D. Anderson Cancer Center\|Genentech, Inc.	Lymphoma	March 2004	Phase 2
NCT00593450	University of Pennsylvania\|National Eye Institute (NEI)	Age Related Macular Degeneration	February 2008	Phase 3
NCT02767219	Moorfields Eye Hospital NHS Foundation Trust	Glaucoma	May 2016	Phase 3
NCT02519348	MedImmune LLC	Hepatocellular Carcinoma	October 19, 2015	Phase 2
NCT01015300	Dartmouth-Hitchcock Medical Center\|Genentech, Inc.	Hemangioblastomas\|Von Hippel Lindau Disease	December 2009	Early Phase 1
NCT00942578	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Metastatic Prostate Cancer	July 16, 2009	Phase 2
NCT05010434	Sun Yat-sen University\|Innovent Biologics (Suzhou) Co. Ltd.	Recurrent Hepatocellular Carcinoma	August 16, 2021	Phase 2
NCT03197571	ImmunityBio, Inc.	Urothelial Carcinoma	December 2017	Phase 1\|Phase 2
NCT02179567	Hellenic Oncology Research Group	NSCLC	March 2010	Phase 2
NCT03382886	University of Utah\|Bristol-Myers Squibb	Hepatocellular Carcinoma	April 11, 2018	Phase 1
NCT04601701	He Eye Hospital	Central Retinal Vein Occlusion	October 17, 2020	Not Applicable
NCT00610493	M.D. Anderson Cancer Center	Advanced Cancer	January 25, 2008	Phase 1
NCT00805961	SCRI Development Innovations, LLC\|Genentech, Inc.\|Novartis	Glioblastoma Multiforme	January 2009	Phase 2
NCT00491738	Genentech, Inc.	Renal Cell Carcinoma	August 2007	Phase 2
NCT03563144	ImmunityBio, Inc.	Metastatic Pancreatic Cancer	August 2018	Phase 2
NCT00673673	Yale University\|Genentech, Inc.	Gastroesophageal Cancer\|Gastric Cancer	May 2008	Phase 2
NCT01215123	Hoffmann-La Roche	Breast Cancer	January 2010
NCT00538005	San Diego Pacific Oncology & Hematology Associates\|National Cancer Institute (NCI)	Melanoma (Skin)	May 2007	Phase 1\|Phase 2
NCT03952403	Shanghai Henlius Biotech	Carcinoma\|Non-Small-Cell Lung	December 2, 2019	Phase 3
NCT00873236	Mount Vernon Cancer Centre at Mount Vernon Hospital\|National Cancer Institute (NCI)	Kidney Cancer	April 2008	Phase 2
NCT04003792	Rabin Medical Center	Liver Metastasis Colon Cancer	January 1, 2020	Phase 2
NCT00217737	National Cancer Institute (NCI)	Colon Mucinous Adenocarcinoma\|Colon Signet Ring Cell Adenocarcinoma\|Lynch Syndrome\|Stage IIA Colon Cancer AJCC v7\|Stage IIB Colon Cancer AJCC v7\|Stage IIC Colon Cancer AJCC v7	August 4, 2005	Phase 3
NCT02456857	M.D. Anderson Cancer Center	Invasive Breast Carcinoma\|Triple-Negative Breast Carcinoma	January 12, 2016	Phase 2
NCT03136406	ImmunityBio, Inc.	Pancreatic Cancer	August 14, 2017	Phase 1\|Phase 2
NCT01156961	Hoffmann-La Roche	Breast Cancer	October 2010	Phase 4
NCT00177307	University of Pittsburgh\|Genentech, Inc.	Cancer	January 2005	Phase 2
NCT01263782	M.D. Anderson Cancer Center\|Eli Lilly and Company\|Genentech, Inc.	Lung Cancer	May 17, 2011	Phase 2
NCT04121455	TME Pharma AG	Glioblastoma	September 12, 2019	Phase 1\|Phase 2
NCT04739202	Hospices Civils de Lyon	Gastric Adenocarcinoma\|Metastatic Gastric Cancer\|Metastatic Adenocarcinoma\|Advanced Gastric Carcinoma	March 19, 2021	Phase 2
NCT00458731	National Cancer Institute (NCI)	Adult Grade III Lymphomatoid Granulomatosis\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Childhood Burkitt Lymphoma\|Childhood Diffuse Large Cell Lymphoma\|Childhood Grade III Lymphomatoid Granulomatosis\|Childhood Immunoblastic Large Cell Lymphoma\|Childhood Nasal Type Extranodal NK+T-cell Lymphoma\|Cutaneous B-cell Non-Hodgkin Lymphoma\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Hepatosplenic T-cell Lymphoma\|Intraocular Lymphoma\|Nodal Marginal Zone B-cell Lymphoma\|Noncutaneous Extranodal Lymphoma\|Peripheral T-cell Lymphoma\|Progressive Hairy Cell Leukemia, Initial Treatment\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Childhood Anaplastic Large Cell Lymphoma\|Recurrent Childhood Large Cell Lymphoma\|Recurrent Childhood Lymphoblastic Lymphoma\|Recurrent Childhood Small Noncleaved Cell Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent+Refractory Childhood Hodgkin Lymphoma\|Refractory Hairy Cell Leukemia\|Small Intestine Lymphoma\|Splenic Marginal Zone Lymphoma\|Stage IV Adult Burkitt Lymphoma\|Stage IV Adult Diffuse Large Cell Lymphoma\|Stage IV Adult Diffuse Mixed Cell Lymphoma\|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma\|Stage IV Adult Hodgkin Lymphoma\|Stage IV Adult Immunoblastic Large Cell Lymphoma\|Stage IV Adult Lymphoblastic Lymphoma\|Stage IV Adult T-cell Leukemia+Lymphoma\|Stage IV Childhood Anaplastic Large Cell Lymphoma\|Stage IV Childhood Hodgkin Lymphoma\|Stage IV Childhood Large Cell Lymphoma\|Stage IV Childhood Lymphoblastic Lymphoma\|Stage IV Childhood Small Noncleaved Cell Lymphoma\|Stage IV Grade 1 Follicular Lymphoma\|Stage IV Grade 2 Follicular Lymphoma\|Stage IV Grade 3 Follicular Lymphoma\|Stage IV Mantle Cell Lymphoma\|Stage IVA Mycosis Fungoides+Sezary Syndrome\|Stage IVB Mycosis Fungoides+Sezary Syndrome\|T-cell Large Granular Lymphocyte Leukemia\|Testicular Lymphoma\|Unspecified Adult Solid Tumor, Protocol Specific\|Unspecified Childhood Solid Tumor, Protocol Specific\|Waldenström Macroglobulinemia	May 2007	Phase 1
NCT00137774	Dana-Farber Cancer Institute\|Massachusetts General Hospital\|Beth Israel Deaconess Medical Center\|Brigham and Women´s Hospital\|Genentech, Inc.\|Schering-Plough	Neuroendocrine Tumors	November 2004	Phase 2
NCT00112528	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Pancreatic Cancer	June 2005	Phase 2
NCT01171170	Dutch Society of Physicians for Pulmonology and Tuberculosis	Non Small Cell Lung Cancer	January 2011	Phase 2
NCT00456261	SCRI Development Innovations, LLC\|Genentech, Inc.\|Eli Lilly and Company	Lung Cancer	March 2007	Phase 2
NCT00455975	SCRI Development Innovations, LLC\|Genentech, Inc.	Renal Cancer\|Kidney Cancer	February 2007	Phase 2
NCT01916447	Taiho Oncology, Inc.	Advanced Gastrointestinal Tumors	September 2013	Phase 1
NCT02396511	Tracon Pharmaceuticals Inc.	Choriocarcinoma	January 2015	Phase 2
NCT00119262	National Cancer Institute (NCI)	Male Breast Cancer\|Stage II Breast Cancer\|Stage IIIA Breast Cancer\|Stage IIIB Breast Cancer	October 2005	Phase 2
NCT03940690	Fondation Ophtalmologique Adolphe de Rothschild	Retinal Telangiectasis\|Coats Disease	October 24, 2019	Phase 3
NCT00436709	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Breast Cancer	July 2006	Not Applicable
NCT00055809	National Cancer Institute (NCI)	Metastatic Gastrointestinal Carcinoid Tumor\|Recurrent Gastrointestinal Carcinoid Tumor\|Regional Gastrointestinal Carcinoid Tumor	January 2003	Phase 2
NCT00129727	Massachusetts General Hospital\|Women and Infants Hospital of Rhode Island	Ovarian Cancer	June 2005	Phase 2
NCT00142480	Massachusetts General Hospital\|Dana-Farber Cancer Institute\|Beth Israel Deaconess Medical Center\|Brigham and Women´s Hospital\|Genentech, Inc.\|Sanofi-Synthelabo\|Hoffmann-La Roche	Biliary Tract Cancer\|Gallbladder Adenocarcinoma	December 2004	Phase 2
NCT05585814	Shanghai Changzheng Hospital	Locally Advanced Colorectal Cancer	October 2022	Phase 2
NCT03117049	Ono Pharmaceutical Co. Ltd\|Bristol-Myers Squibb	Non-Small Cell Lung Cancer	June 13, 2017	Phase 3
NCT01085734	Maturi, Raj K., M.D., P.C.	Retinal Vein Occlusions	March 2010	Phase 4
NCT04727307	University Hospital, Montpellier	Hepatocellular Carcinoma	January 26, 2021	Phase 2
NCT00408408	NSABP Foundation Inc\|National Cancer Institute (NCI)	Breast Cancer	November 2006	Phase 3
NCT01135498	Hoffmann-La Roche	Colorectal Cancer	November 2006	Phase 2
NCT00025337	National Cancer Institute (NCI)	Adenocarcinoma of the Colon\|Adenocarcinoma of the Rectum\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage III Colon Cancer\|Stage III Rectal Cancer\|Stage IV Colon Cancer\|Stage IV Rectal Cancer	September 2001	Phase 3
NCT03533127	Luye Pharma Group Ltd.	Non Small Cell Lung Cancer\|Non Small Cell Lung Cancer Metastatic\|Non Small Cell Lung Cancer Recurrent	November 27, 2017	Phase 3
NCT00717405	Hoffmann-La Roche	Breast Cancer	October 2008	Phase 2
NCT00932152	University of Pittsburgh	Non-small Cell Lung Cancer\|Postmenopausal Women	September 2010	Phase 2
NCT00022607	California Cancer Consortium\|National Cancer Institute (NCI)	Multiple Myeloma and Plasma Cell Neoplasm	January 2002	Phase 2
NCT02654639	Georgetown University	Metastatic Colorectal Cancer	February 2016	Phase 2
NCT02467907	Hoffmann-La Roche	Cervical Cancer	July 28, 2015	Phase 2
NCT01562028	ETOP IBCSG Partners Foundation\|Spanish Lung Cancer Group	Lung Cancer	June 2012	Phase 2
NCT00556205	Massachusetts General Hospital\|Beth Israel Deaconess Medical Center\|Pfizer	Renal Cell Carcinoma	September 2009	Phase 2
NCT02971501	National Cancer Institute (NCI)	Metastatic Lung Non-Small Cell Carcinoma\|Metastatic Malignant Neoplasm in the Brain\|Stage IV Lung Non-Small Cell Cancer AJCC v7	June 23, 2017	Phase 2
NCT00964704	Hoffmann-La Roche	Breast Cancer	March 2011	Phase 2
NCT00460174	Northwestern University\|National Cancer Institute (NCI)	Pancreatic Cancer	October 10, 2005	Phase 2
NCT00336323	Jaeb Center for Health Research\|National Eye Institute (NEI)	Diabetic Retinopathy	June 2006	Phase 2
NCT04017455	The Netherlands Cancer Institute\|Hoffmann-La Roche	Rectal Cancer	October 22, 2019	Phase 2
NCT03818061	Centre Leon Berard	Head and Neck Neoplasms	March 26, 2019	Phase 2
NCT01763645	Biocad	Non-small Cell Lung Cancer	October 2012	Phase 3
NCT00109226	Genentech, Inc.	Colorectal Cancer	August 2000	Phase 2
NCT01044329	Shahid Beheshti University of Medical Sciences\|Labbafinejad Medical Center	Branch Retinal Vein Occlusion	January 2010	Phase 2
NCT01170767	Hospices Civils de Lyon	Age Related Macular Degeneration	June 2009	Phase 3
NCT00511459	Amgen	Locally Recurrent and Metastatic Breast Cancer	July 2007	Phase 2
NCT04682210	Sun Yat-sen University	HCC\|Adjuvant Therapy\|Immunotherapy	December 2020	Phase 3
NCT05540951	Fudan University	Colorectal Cancer	June 1, 2018	Phase 3
NCT00392665	Massachusetts General Hospital\|Dana-Farber Cancer Institute\|Emory University\|University of North Carolina, Chapel Hill\|Genentech, Inc.\|OSI Pharmaceuticals	Squamous Cell Carcinoma of the Head and Neck (SCCHN)	October 2006	Phase 2
NCT05444374	Sichuan Cancer Hospital and Research Institute	Cervical Cancer	October 1, 2022	Phase 2
NCT00806923	Hoffmann-La Roche	Non-Squamous Non-Small Cell Lung Cancer	February 2005	Phase 3
NCT01166594	Sunnybrook Health Sciences Centre\|Glaucoma Research Society of Canada	Glaucoma\|Optic Neuropathy\|Fibrosis	June 2010	Phase 4
NCT02620800	Celgene	Metastatic Pancreas Adenocarcinoma	January 18, 2016	Phase 1
NCT00027703	National Cancer Institute (NCI)	Advanced Malignant Mesothelioma\|Epithelial Mesothelioma\|Localized Malignant Mesothelioma\|Recurrent Malignant Mesothelioma\|Sarcomatous Mesothelioma	October 2001	Phase 2
NCT03635021	Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)\|Amgen	Colorectal Cancer	October 15, 2018	Phase 3
NCT03203447	Clearside Biomedical, Inc.	Macular Edema\|Retinal Vein Occlusion	March 5, 2018	Phase 3
NCT01946529	St. Jude Children´s Research Hospital\|University of Tennessee Health Science Center\|University of Florida\|Nemours Children´s Clinic	Desmoplastic Small Round Cell Tumor\|Ewing Sarcoma of Bone or Soft Tissue\|Localized Ewing Sarcoma+Peripheral Primitive Neuroectodermal Tumor\|Metastatic Ewing Sarcoma+Peripheral Primitive Neuroectodermal Tumor	December 27, 2013	Phase 2
NCT00925652	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Beth Israel Deaconess Medical Center\|Translational Breast Cancer Research Consortium\|Genentech, Inc.	Breast Cancer	September 2010	Phase 2
NCT01102595	Grupo Español de Investigación en Neurooncología	Glioblastomas	December 2009	Phase 2
NCT02174172	Hoffmann-La Roche	Solid Cancers	August 18, 2014	Phase 1
NCT05087992	Boehringer Ingelheim	Gastrointestinal Cancer, Metastatic	November 24, 2021	Phase 1
NCT02175446	Consorzio Oncotech\|Clinical Research Technology S.r.l.	Metastatic Breast Cancer\|Human Epidermal Growth Factor 2 Negative Carcinoma of Breast	September 2014	Phase 2
NCT02496286	Eastern Regional Medical Center	Malignant Ascites	June 2015	Phase 1
NCT01588184	Hoffmann-La Roche	Neoplasms	July 13, 2012	Phase 4
NCT02873962	Dana-Farber Cancer Institute\|Bristol-Myers Squibb	Peritoneal Cancer\|Ovarian Cancer\|Fallopian Tube Cancer	November 10, 2016	Phase 2
NCT00062426	Prologue Research International\|National Cancer Institute (NCI)	Colorectal Cancer	May 2003	Phase 3
NCT00775073	Gerhard Treiber\|Crolll Gmbh\|Estimate, GmbH\|Janssen Diagnostics, LLC\|Treiber, Gerhard	Hepatocellular Carcinoma	October 2008	Phase 2
NCT00222469	University of Oklahoma\|Genentech, Inc.\|Sanofi\|M.D. Anderson Cancer Center	Metastatic Pancreatic Cancer	August 2005	Phase 2
NCT04527068	Second Affiliated Hospital, School of Medicine, Zhejiang University\|Qilu Pharmaceutical Co., Ltd.\|Shanghai Junshi Bioscience Co., Ltd.	Refractory Metastatic Colorectal Cancer\|pMMR\|MSS	September 20, 2020	Phase 2
NCT01303926	Gruppo Oncologico Italia Meridionale	Non-squamous Nonsmall Cell Neoplasm of Lung	January 2010	Phase 3
NCT00081614	Genentech, Inc.	Renal Cell Carcinoma\|Metastases	March 2004	Phase 2
NCT03337698	Hoffmann-La Roche	Carcinoma, Non-Small-Cell Lung	January 2, 2018	Phase 1\|Phase 2
NCT02663141	Tehran University of Medical Sciences\|Farabi Eye Hospital	Diabetic Macular Edema	June 2015	Phase 2
NCT01057264	M.D. Anderson Cancer Center	Advanced Cancers	January 2010	Phase 1
NCT04421378	Karyopharm Therapeutics Inc	Glioblastoma Multiforme	June 8, 2020	Phase 1\|Phase 2
NCT02821559	Centre Hospitalier Universitaire de Besancon\|Hospira, now a wholly owned subsidiary of Pfizer	Metastatic Colorectal Cancer	July 2012	Phase 2
NCT01454102	Bristol-Myers Squibb	Non-small Cell Lung Cancer	December 16, 2011	Phase 1
NCT01763671	Intergroupe Francophone de Cancerologie Thoracique	Non-squamous Non-small Cell Lung Cancer	May 2013	Phase 3
NCT03690739	AGO Research GmbH	Recurrent Ovarian Carcinoma	August 9, 2019	Phase 3
NCT02192970	University of Wisconsin, Madison	Retinal Detachment\|Proliferative Vitreoretinopathy	January 21, 2015	Phase 2
NCT00401817	Weill Medical College of Cornell University	Untreated Mantle Cell Lymphoma	November 2007	Phase 2
NCT01408953	Tirgan, Michael H., M.D.	Keloid	February 2012	Phase 2
NCT00234494	Christopher Sweeney, MBBS\|Genentech, Inc.\|Eli Lilly and Company\|Walther Cancer Institute\|Hoosier Cancer Research Network	Bladder Cancer	November 2005	Phase 2
NCT01383707	Hoffmann-La Roche	Colorectal Cancer	August 12, 2011	Phase 2
NCT01950390	National Cancer Institute (NCI)	Stage IIIC Cutaneous Melanoma AJCC v7\|Stage IV Cutaneous Melanoma AJCC v6 and v7\|Unresectable Melanoma	December 13, 2013	Phase 2
NCT00937560	Hoffmann-La Roche	Ovarian Cancer	June 25, 2009	Phase 2
NCT04861948	Innovent Biologics (Suzhou) Co. Ltd.	Solid Tumors\|Lung Adenocarcinoma\|Osteosarcoma	May 25, 2021	Phase 1
NCT00564148	Ophthalmological Association Edelweiss	Retinal Neovascularization	July 2007	Phase 2
NCT01374425	Genentech, Inc.	Colorectal Cancer	August 2011	Phase 2
NCT02754882	Samsung Bioepis Co., Ltd.	Lung Cancer\|Non-small Cell Lung Cancer	July 5, 2016	Phase 3
NCT02891824	ARCAGY+ GINECO GROUP\|Hoffmann-La Roche	Ovarian Cancer	September 22, 2016	Phase 3
NCT03387111	ImmunityBio, Inc.	Squamous Cell Carcinoma	January 13, 2018	Phase 1\|Phase 2
NCT02919371	King Faisal Specialist Hospital & Research Center	Renal Cell Carcinoma	December 2014	Phase 1\|Phase 2
NCT01422018	Seoul St. Mary´s Hospital	Diabetes Complications	August 2011	Not Applicable
NCT01435395	Emory University\|Schering-Plough\|Genentech, Inc.\|Millennium Pharmaceuticals, Inc.	Glioblastoma Multiforme	December 2011	Phase 1
NCT00404703	Hoffmann-La Roche	Non-Small Cell Lung Cancer	August 2006	Phase 2
NCT00531024	The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery	Macular Degeneration	August 2005	Phase 2\|Phase 3
NCT00904839	Boehringer Ingelheim	Colorectal Neoplasms	May 2009	Phase 2
NCT05052099	University Hospital, Essen	Biliary Tract Cancer	October 2021	Phase 1\|Phase 2
NCT02436993	University of California, Irvine	Breast Carcinoma	April 2015	Phase 2
NCT01972490	Xu jianmin\|Fudan University	Colorectal Neoplasms	October 2013	Phase 4
NCT02363751	UNICANCER	Collecting Duct Carcinoma (Kidney)	December 2014	Phase 2
NCT00378638	Chap, Linnea I., M.D.\|Genentech, Inc.	Breast Cancer	June 2006	Phase 2
NCT00113217	M.D. Anderson Cancer Center\|Genentech, Inc.	Renal Cell Carcinoma\|Kidney Cancer	February 2005	Phase 2
NCT01032109	Kumamoto University	Age-related Macular Degeneration	October 2006	Not Applicable
NCT03329248	ImmunityBio, Inc.	Pancreatic Cancer	November 6, 2017	Phase 1\|Phase 2
NCT00577109	Hoffmann-La Roche\|Merck KGaA, Darmstadt, Germany	Colorectal Cancer	December 2007	Phase 2
NCT02835833	University of Alabama at Birmingham\|Boehringer Ingelheim	Renal Cell Carcinoma\|Colorectal Adenocarcinoma\|Non-squamous Non-small Cell Lung Cancer\|Platinum-refractory Ovarian Carcinoma\|Cervical Carcinoma	June 9, 2016	Phase 1
NCT04262687	Federation Francophone de Cancerologie Digestive	Colorectal Cancer Metastatic\|High Immune Infiltrate\|Microsatellite Stable	April 6, 2021	Phase 2
NCT03272217	Arjun Balar, MD\|Roche-Genentech\|Hoosier Cancer Research Network	Urothelial Carcinoma	September 13, 2017	Phase 2
NCT01380678	Khon Kaen University	Pterygium\|Inflammation	January 2009	Phase 3
NCT00326911	Eli Lilly and Company	Metastatic Pancreatic Cancer	May 2006	Phase 2
NCT05330065	The First Affiliated Hospital of Zhengzhou University	Malignant Pleural Effusion	August 1, 2022	Phase 1\|Phase 2
NCT04660812	Arcus Biosciences, Inc.\|Gilead Sciences	Metastatic Colorectal Cancer	May 10, 2021	Phase 1\|Phase 2
NCT01608087	Boehringer Ingelheim	Healthy	May 1, 2012	Phase 1
NCT05593328	Cardiff Oncology	Colorectal Cancer\|Metastatic Colorectal Cancer	November 2022	Phase 2
NCT01229202	Nova Scotia Health Authority	Glaucoma	July 2008	Phase 4
NCT01487629	University of Sao Paulo\|Fundação de Amparo à Pesquisa do Estado de São Paulo	Diabetic Retinopathy\|Macular Edema	April 2010	Phase 2
NCT00023959	National Cancer Institute (NCI)	Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma\|Recurrent Adenoid Cystic Carcinoma of the Oral Cavity\|Recurrent Basal Cell Carcinoma of the Lip\|Recurrent Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity\|Recurrent Inverted Papilloma of the Paranasal Sinus and Nasal Cavity\|Recurrent Lymphoepithelioma of the Nasopharynx\|Recurrent Lymphoepithelioma of the Oropharynx\|Recurrent Metastatic Squamous Neck Cancer With Occult Primary\|Recurrent Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity\|Recurrent Mucoepidermoid Carcinoma of the Oral Cavity\|Recurrent Salivary Gland Cancer\|Recurrent Squamous Cell Carcinoma of the Hypopharynx\|Recurrent Squamous Cell Carcinoma of the Larynx\|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity\|Recurrent Squamous Cell Carcinoma of the Nasopharynx\|Recurrent Squamous Cell Carcinoma of the Oropharynx\|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity\|Recurrent Verrucous Carcinoma of the Larynx\|Recurrent Verrucous Carcinoma of the Oral Cavity\|Stage III Adenoid Cystic Carcinoma of the Oral Cavity\|Stage III Basal Cell Carcinoma of the Lip\|Stage III Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity\|Stage III Inverted Papilloma of the Paranasal Sinus and Nasal Cavity\|Stage III Lymphoepithelioma of the Nasopharynx\|Stage III Lymphoepithelioma of the Oropharynx\|Stage III Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity\|Stage III Mucoepidermoid Carcinoma of the Oral Cavity\|Stage III Salivary Gland Cancer\|Stage III Squamous Cell Carcinoma of the Hypopharynx\|Stage III Squamous Cell Carcinoma of the Larynx\|Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity\|Stage III Squamous Cell Carcinoma of the Nasopharynx\|Stage III Squamous Cell Carcinoma of the Oropharynx\|Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity\|Stage III Verrucous Carcinoma of the Larynx\|Stage III Verrucous Carcinoma of the Oral Cavity\|Stage IV Adenoid Cystic Carcinoma of the Oral Cavity\|Stage IV Basal Cell Carcinoma of the Lip\|Stage IV Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity\|Stage IV Inverted Papilloma of the Paranasal Sinus and Nasal Cavity\|Stage IV Lymphoepithelioma of the Nasopharynx\|Stage IV Lymphoepithelioma of the Oropharynx\|Stage IV Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity\|Stage IV Mucoepidermoid Carcinoma of the Oral Cavity\|Stage IV Salivary Gland Cancer\|Stage IV Squamous Cell Carcinoma of the Hypopharynx\|Stage IV Squamous Cell Carcinoma of the Larynx\|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity\|Stage IV Squamous Cell Carcinoma of the Nasopharynx\|Stage IV Squamous Cell Carcinoma of the Oropharynx\|Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity\|Stage IV Verrucous Carcinoma of the Larynx\|Stage IV Verrucous Carcinoma of the Oral Cavity\|Untreated Metastatic Squamous Neck Cancer With Occult Primary	July 2001	Phase 1
NCT01917877	Qingdao Central Hospital	Pulmonary Fibrosis	August 2013	Phase 2
NCT00976911	Hoffmann-La Roche	Ovarian Cancer	October 29, 2009	Phase 3
NCT04872582	XIANG YANQUN\|Sun Yat-sen University	Recurrent Nasopharyngeal Carcinoma\|Metastatic Nasopharyngeal Carcinoma\|Chemotherapy Effect	July 29, 2021	Phase 2
NCT00600210	Leo W. Jenkins Cancer Center\|Genentech, Inc.	Cervical Cancer	January 2008	Phase 2
NCT01128699	Vanak Eye Surgery Center	Refractory Glaucoma	May 2010	Phase 3
NCT00402883	SCRI Development Innovations, LLC\|Genentech, Inc.\|Eli Lilly and Company	Lung Cancer	November 2006	Phase 2
NCT00281697	Genentech, Inc.	Metastatic Breast Cancer	February 2006	Phase 3
NCT00434252	Genentech, Inc.	Melanoma	February 2007	Phase 2
NCT00019539	National Cancer Institute (NCI)	Stage IV Renal Cell Cancer\|Recurrent Renal Cell Cancer	November 1998	Phase 2
NCT00434642	Genentech, Inc.	Ovarian Cancer	April 2007	Phase 3
NCT03169738	ImmunityBio, Inc.	Non-small Cell Lung Cancer	February 2018	Phase 1\|Phase 2
NCT00520013	Dana-Farber Cancer Institute\|Genentech, Inc.\|Beth Israel Deaconess Medical Center\|Brigham and Women´s Hospital\|Massachusetts General Hospital	Ovarian Cancer\|Fallopian Tube Cancer\|Primary Peritoneal Cancer\|Papillary Serous Mullerian Tumor\|Clear Cell Mullerian Tumor	August 2007	Phase 2
NCT03554707	SynerGene Therapeutics, Inc.	Childhood CNS Tumor	June 2022	Early Phase 1
NCT00566761	Asociación para Evitar la Ceguera en México	Macular Edema\|Central Retinal Vein Occlusion	June 2007	Phase 4
NCT00126542	National Cancer Institute (NCI)	Fallopian Tube Cancer\|Primary Peritoneal Cavity Cancer\|Recurrent Ovarian Epithelial Cancer\|Stage IV Ovarian Epithelial Cancer	April 2005	Phase 2
NCT04510584	University Health Network, Toronto	Ovarian Endometrioid Tumor\|Fallopian Tube Cancer\|Primary Peritoneal Cancer\|TP53 Mutation	July 16, 2021	Phase 2
NCT01507740	Medical University Innsbruck	Hepatocellular Cancer\|Non-small Cell Lung Cancer\|Renal Cell Cancer\|Colorectal Cancer	July 2009
NCT01091792	Dartmouth-Hitchcock Medical Center\|Genentech, Inc.	Glioblastoma Multiforme	March 2010	Early Phase 1
NCT01043484	Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)\|Hoffmann-La Roche	Rectal Cancer	December 2009	Phase 2
NCT05132413	Suzhou Suncadia Biopharmaceuticals Co., Ltd.	Advanced or Metastatic Non-squamous Non-small-cell Lung Cancer	December 30, 2021	Phase 3
NCT02901236	Athens Vision Eye Institute	Glaucoma	January 2014	Phase 2\|Phase 3
NCT00595322	Memorial Sloan Kettering Cancer Center\|Weill Medical College of Cornell University\|Genentech, Inc.	Brain Cancer\|Recurrent Malignant Gliomas\|Primary Brain Tumor	December 2005	Not Applicable
NCT03220932	Hospices Civils de Lyon	Ovarian Epithelial Cancer	November 30, 2019	Phase 3
NCT00913913	Dartmouth-Hitchcock Medical Center\|National Cancer Institute (NCI)	Metastatic Renal Cell Carcinoma	February 2009	Phase 2
NCT00347165	Asociación para Evitar la Ceguera en México	Age Related Macular Degeneration	September 2005	Phase 2
NCT00410956	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Liver Cancer	May 2007	Phase 2
NCT00137826	Dana-Farber Cancer Institute\|Massachusetts General Hospital\|University of Chicago	Mesothelioma	February 2004	Phase 2
NCT03246152	Cairo University	Diabetic Macular Edema\|Ischemic Maculopathy	October 23, 2017	Phase 4
NCT01722968	Theodoros Foukakis\|Karolinska University Hospital	Breast Cancer	November 2012	Phase 2
NCT01152203	M.D. Anderson Cancer Center\|Cephalon\|National Comprehensive Cancer Network	Advanced Cancer	June 2010	Phase 1
NCT03737643	AstraZeneca\|European Network of Gynaecological Oncological Trial Groups (ENGOT)\|GOG Foundation, Inc. (GOG Foundation)\|Myriad Genetic Laboratories, Inc.	Advanced Ovarian Cancer	January 4, 2019	Phase 3
NCT03713944	Nasser Hanna\|Genentech, Inc.\|Big Ten Cancer Research Consortium	NSCLC Stage IV\|NSCLC, Recurrent	November 15, 2018	Phase 2
NCT00651456	Intergroupe Francophone de Cancerologie Thoracique\|University Hospital, Caen\|Groupe Francais De Pneumo-Cancerologie	Mesothelioma	February 2008	Phase 2\|Phase 3
NCT00773695	Hoffmann-La Roche\|Norwegian Radium Hospital	Breast Cancer	November 7, 2008	Phase 2
NCT05214339	Sun Yat-sen University\|Third Affiliated Hospital, Sun Yat-Sen University\|Nanfang Hospital of Southern Medical University\|Xiangya Hospital of Central South University	Unresectable Hepatocellular Carcinoma\|Hepatocellular Carcinoma by BCLC Stage	March 16, 2022	Phase 2
NCT04299880	Sumitomo Pharma Oncology, Inc.	Oncology	February 24, 2020	Phase 1
NCT00118261	Case Comprehensive Cancer Center\|National Cancer Institute (NCI)	Colorectal Cancer	March 2005	Phase 1
NCT00537823	Washington University School of Medicine	Colorectal Cancer\|Metastases	June 2007	Phase 2
NCT01004874	Duke University\|Genentech, Inc.\|GlaxoSmithKline	Malignant Glioma\|Glioblastoma\|Gliosarcoma	December 30, 2009	Phase 2
NCT00370630	Shahid Beheshti University of Medical Sciences	Retinovascular Disease	August 2006	Phase 2
NCT02031991	Pfizer	Healthy	January 2014	Phase 1
NCT00047710	M.D. Anderson Cancer Center\|Genentech, Inc.	Pancreatic Cancer	September 2002	Phase 1
NCT02640365	GERCOR - Multidisciplinary Oncology Cooperative Group\|Merrimack Pharmaceuticals	Unresectable Advanced Cancer	November 18, 2015	Phase 1
NCT01498328	Celldex Therapeutics	Glioblastoma\|Small Cell Glioblastoma\|Giant Cell Glioblastoma\|Gliosarcoma\|Glioblastoma With Oligodendroglial Component\|Recurrent Glioblastoma\|Relapsed Glioblastoma	December 2011	Phase 2
NCT00553800	Fox Chase Cancer Center\|Genentech, Inc.\|OSI Pharmaceuticals	Carcinoma, Non-Small-Cell Lung	July 5, 2007	Phase 2
NCT02574078	Bristol-Myers Squibb	Non-Small Cell Lung Cancer	November 23, 2015	Phase 1\|Phase 2
NCT04310176	National Cancer Institute, Naples	Ras-mutated Metastatic Colorectal Cancer	May 24, 2019	Phase 2
NCT00957125	Thomas Hatschek\|Karolinska University Hospital	Breast Cancer	September 2008	Phase 2
NCT00357318	National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	June 2006	Phase 1
NCT04991350	Cairo University	Diabetic Macular Edema\|Macular Ischemia\|Diabetic Retinopathy\|Vascular Endothelial Growth Factor Overexpression	November 26, 2021	Phase 4
NCT00262847	National Cancer Institute (NCI)\|NRG Oncology	Fallopian Tube Clear Cell Adenocarcinoma\|Fallopian Tube Endometrioid Adenocarcinoma\|Fallopian Tube Mucinous Adenocarcinoma\|Fallopian Tube Serous Adenocarcinoma\|Fallopian Tube Transitional Cell Carcinoma\|Malignant Ovarian Mixed Epithelial Tumor\|Ovarian Brenner Tumor\|Ovarian Clear Cell Adenocarcinoma\|Ovarian Endometrioid Adenocarcinoma\|Ovarian Mucinous Adenocarcinoma\|Ovarian Serous Adenocarcinoma\|Ovarian Transitional Cell Carcinoma\|Primary Peritoneal Serous Adenocarcinoma\|Stage IIIA Fallopian Tube Cancer\|Stage IIIA Ovarian Cancer\|Stage IIIA Primary Peritoneal Cancer\|Stage IIIB Fallopian Tube Cancer\|Stage IIIB Ovarian Cancer\|Stage IIIB Primary Peritoneal Cancer\|Stage IIIC Fallopian Tube Cancer\|Stage IIIC Ovarian Cancer\|Stage IIIC Primary Peritoneal Cancer\|Stage IV Fallopian Tube Cancer\|Stage IV Ovarian Cancer\|Stage IV Primary Peritoneal Cancer\|Undifferentiated Fallopian Tube Carcinoma\|Undifferentiated Ovarian Carcinoma	September 2005	Phase 3
NCT00384631	Shahid Beheshti University of Medical Sciences	Neovascular\|Glaucoma	April 2006	Not Applicable
NCT02420821	Hoffmann-La Roche	Renal Cell Carcinoma	May 20, 2015	Phase 3
NCT02810457	Centus Biotherapeutics Limited	Carcinoma, Non-Small-Cell Lung	September 7, 2016	Phase 3
NCT00324805	National Cancer Institute (NCI)\|Cancer and Leukemia Group B\|NCIC Clinical Trials Group\|North Central Cancer Treatment Group\|Southwest Oncology Group	Stage IB Lung Non-Small Cell Carcinoma AJCC v7\|Stage IIA Lung Non-Small Cell Carcinoma AJCC v7\|Stage IIB Lung Non-Small Cell Carcinoma AJCC v7\|Stage IIIA Lung Non-Small Cell Cancer AJCC v7	June 1, 2007	Phase 3
NCT03555149	Hoffmann-La Roche	Colorectal Cancer	September 27, 2018	Phase 1\|Phase 2
NCT03050814	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Colorectal Tumors\|Colorectal Neoplasms\|Colorectal Carcinoma\|Colorectal Adenocarcinoma\|Colorectal Cancer	April 5, 2017	Phase 2
NCT00130520	University of Arizona\|Genentech, Inc.	Ovarian Neoplasms	June 2005	Phase 2
NCT00417716	Asociación para Evitar la Ceguera en México	Diabetes Mellitus Type 2\|Diabetic Macular Edema	September 2005	Phase 3
NCT01552434	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Advanced Malignant Neoplasm\|Castleman Disease\|Digestive System Carcinoma\|Erdheim-Chester Disease\|Lip and Oral Cavity Carcinoma\|Lymphangioleiomyomatosis\|Malignant Endocrine Neoplasm\|Malignant Female Reproductive System Neoplasm\|Malignant Male Reproductive System Neoplasm\|Malignant Neoplasm\|Malignant Respiratory Tract Neoplasm\|Malignant Thoracic Neoplasm\|Malignant Urinary System Neoplasm\|Mesothelial Neoplasm\|Metastatic Malignant Neoplasm\|Metastatic Urothelial Carcinoma\|Neurofibromatosis Type 2\|Recurrent Adult Soft Tissue Sarcoma\|Recurrent Breast Carcinoma\|Recurrent Childhood Soft Tissue Sarcoma\|Recurrent Digestive System Carcinoma\|Recurrent Female Reproductive System Carcinoma\|Recurrent Male Reproductive System Carcinoma\|Recurrent Malignant Neoplasm\|Recurrent Pharyngeal Carcinoma\|Recurrent Thyroid Gland Carcinoma\|Refractory Malignant Neoplasm\|Soft Tissue Neoplasm\|Stage III Breast Cancer AJCC v7\|Stage III Pharyngeal Cancer\|Stage IIIA Breast Cancer AJCC v7\|Stage IIIB Breast Cancer AJCC v7\|Stage IIIC Breast Cancer AJCC v7\|Stage IV Breast Cancer AJCC v6 and v7\|Stage IV Pharyngeal Cancer\|Stage IVA Pharyngeal Cancer\|Stage IVB Pharyngeal Cancer\|Stage IVC Pharyngeal Cancer\|Thyroid Gland Neoplasm	March 16, 2012	Phase 1
NCT02033031	Medical University of Vienna	Branch Retinal Vein Occlusion	August 2012	Phase 3
NCT01588990	Hoffmann-La Roche	Colorectal Neoplasms	June 26, 2012	Phase 4
NCT01201850	University of Colorado, Denver\|Genentech, Inc.	Radiation Necrosis	June 28, 2010	Not Applicable
NCT01937715	Pfizer	Metastatic Colorectal Carcinoma	February 2014	Phase 1\|Phase 2
NCT00323011	University of Southern California\|Pfizer	Colorectal Cancer	May 2006	Phase 2
NCT02389959	Stanford University	HHT\|Hereditary Hemorrhagic Telangiectasia\|Epistaxis\|Nose Bleeds\|Nasal Bleeding	August 4, 2014	Phase 4
NCT00533585	M.D. Anderson Cancer Center\|Bayer	Lung Cancer	May 2006	Phase 1
NCT00952029	Federation Francophone de Cancerologie Digestive	Colorectal Cancer	March 2010	Phase 2\|Phase 3
NCT01249521	Austin Health	Metastatic Colorectal Cancer	November 2010	Phase 2
NCT04974944	Sun Yat-sen University	Stage IVB Cervical Cancer\|Recurrent Cervical Cancer\|Persistent Cervical Cancer	July 30, 2021	Phase 2
NCT00399750	Sanofi	Colorectal Cancer	November 2002	Phase 2
NCT00095459	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Neoplasms	November 2, 2004	Phase 1
NCT01083368	Case Comprehensive Cancer Center	Prostate Cancer	January 2009	Phase 1\|Phase 2
NCT00974584	Genentech, Inc.	Non-Squamous Non-Small Cell Lung Cancer	October 2009	Phase 1
NCT01525082	Shaheen Shagufta\|National Cancer Institute (NCI)\|Stanford University	Gastrinoma\|Glucagonoma\|Insulinoma\|Pancreatic Polypeptide Tumor\|Recurrent Islet Cell Carcinoma\|Recurrent Pancreatic Cancer\|Somatostatinoma\|Stage III Pancreatic Cancer\|Stage IV Pancreatic Cancer	December 2012	Phase 2
NCT00967330	Hoffmann-La Roche	Glioblastoma Multiforme	June 2010	Phase 2
NCT00088894	National Cancer Institute (NCI)	Adenocarcinoma of the Pancreas\|Recurrent Pancreatic Cancer\|Stage II Pancreatic Cancer\|Stage III Pancreatic Cancer\|Stage IV Pancreatic Cancer	June 2004	Phase 3
NCT02743078	RTOG Foundation, Inc.\|NovoCure Ltd.	Glioblastoma\|Glioma\|Gliosarcoma	May 9, 2017	Phase 2
NCT05525858	Seoul National University Bundang Hospital\|Korean Cancer Study Group\|Roche Pharma AG	Solid Tumor\|Advanced Solid Tumor\|Metastatic Cancer	September 28, 2022
NCT01900717	Centre Hospitalier Universitaire Dijon	Metastatic Colorectal Adenocarcinoma	July 2011	Phase 2
NCT03376659	Georgetown University\|Mayo Clinic\|Indiana University\|Emory University\|National Cancer Institute (NCI)\|George Mason University\|Thomas Jefferson University\|MedImmune LLC\|Bavarian Nordic	Metastatic Colorectal Cancer\|Colorectal Adenocarcinoma\|Pancreatic Adenocarcinoma\|Metastatic Pancreatic Cancer	August 8, 2018	Phase 1\|Phase 2
NCT03038100	Hoffmann-La Roche\|GOG Foundation\|European Network of Gynaecological Oncological Trial Groups (ENGOT)	Ovarian Cancer\|Fallopian Tube Cancer\|Peritoneal Neoplasms	March 8, 2017	Phase 3
NCT00625898	NSABP Foundation Inc\|Cancer International Research Group (CIRG)\|Hoffmann-La Roche\|Genentech, Inc.	Breast Cancer	April 2008	Phase 3
NCT03037736	University of California, San Francisco	Pterygium of Conjunctiva and Cornea	March 1, 2020	Phase 4
NCT00323739	SCRI Development Innovations, LLC\|Genentech, Inc.\|Novartis	Kidney Cancer	May 2006	Phase 2
NCT00515684	Yonsei University	Corneal Neovascularization	May 2007	Not Applicable
NCT05303259	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Brain Injuries	November 1, 2021	Phase 2
NCT01658033	Fudan University	Metastatic Breast Cancer	May 2012	Phase 2
NCT00026221	National Cancer Institute (NCI)	Recurrent Melanoma\|Stage IV Skin Melanoma	November 2001	Phase 2
NCT01320683	City of Hope Medical Center\|National Cancer Institute (NCI)	Liver Metastases\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer	March 2011	Phase 2
NCT00867321	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Liver Cancer	April 2009	Phase 1\|Phase 2
NCT01047059	University of Cologne	Non-Small-Cell Lung Carcinoma	January 2010	Phase 2
NCT00378703	National Cancer Institute (NCI)	Clear Cell Renal Cell Carcinoma\|Recurrent Renal Cell Carcinoma\|Stage IV Renal Cell Cancer AJCC v7	September 14, 2007	Phase 2
NCT00321828	NSABP Foundation Inc\|National Cancer Institute (NCI)	Colorectal Cancer	March 2006	Phase 2
NCT00370422	Shahid Beheshti University of Medical Sciences	Diabetic Macular Edema	November 2005	Phase 3
NCT01105702	NYU Langone Health\|Genentech, Inc.\|Atlantic Health System	Brain Cancer	May 2010	Phase 2
NCT02342379	The University of Texas Health Science Center at San Antonio	Glioblastoma	May 2015	Phase 2
NCT00816595	Mayo Clinic\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	February 2009	Phase 2
NCT01898130	Northwestern University\|Genentech, Inc.	Metastatic Cancer\|Unspecified Adult Solid Tumor, Protocol Specific	November 27, 2013	Phase 2
NCT00741195	Hellenic Oncology Research Group	Non-small-cell Lung Cancer	April 2008	Phase 2
NCT05109052	University of Rochester	Hepatocellular Carcinoma\|Cancer of Liver	September 20, 2022	Phase 1\|Phase 2
NCT00320541	Eli Lilly and Company\|Genentech, Inc.	Breast Cancer	May 2006	Phase 2
NCT04732286	Hoffmann-La Roche	Carcinoma, Hepatocellular	May 4, 2021	Phase 3
NCT01763450	Liaoning Tumor Hospital & Institute	Liver Metastases\|Colorectal Cancer	September 2012	Phase 2
NCT03990103	China Medical University, China	Metastatic Gastric Adenocarcinoma	November 1, 2017	Phase 2
NCT01229813	Lund University Hospital\|Hoffmann-La Roche	Colorectal Cancer	October 2010	Phase 3
NCT01551745	Gradalis, Inc.	Stage III Ovarian Cancer\|Stage IV Ovarian Cancer	March 2012	Phase 2
NCT00460603	Pfizer	Colorectal Neoplasms	January 2006	Phase 1\|Phase 2
NCT00397982	National Cancer Institute (NCI)\|Fox Chase Cancer Center	Recurrent Melanoma\|Stage IIIB Skin Melanoma\|Stage IIIC Skin Melanoma\|Stage IV Skin Melanoma	January 2008	Phase 2
NCT00407719	Johns Hopkins University	Choroidal Neovascularization\|Degenerative Myopia\|Pathological Myopia	June 2005	Phase 1
NCT03169764	ImmunityBio, Inc.	Head and Neck Squamous Cell Carcinoma	December 2017	Phase 1\|Phase 2
NCT01414153	Lpath, Inc.	Exudative Age-related Macular Degeneration	August 2012	Phase 2
NCT02072720	Amsterdam UMC, location VUmc\|Noordwest Ziekenhuisgroep\|Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	Primary Esophageal Carcinoma	February 2014	Early Phase 1
NCT00588770	National Cancer Institute (NCI)	Neck Squamous Cell Carcinoma of Unknown Primary\|Recurrent Hypopharyngeal Squamous Cell Carcinoma\|Recurrent Laryngeal Squamous Cell Carcinoma\|Recurrent Laryngeal Verrucous Carcinoma\|Recurrent Lip and Oral Cavity Squamous Cell Carcinoma\|Recurrent Neck Squamous Cell Carcinoma of Unknown Primary\|Recurrent Oral Cavity Verrucous Carcinoma\|Recurrent Oropharyngeal Squamous Cell Carcinoma\|Recurrent Salivary Gland Carcinoma\|Recurrent Sinonasal Squamous Cell Carcinoma\|Salivary Gland Squamous Cell Carcinoma\|Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7\|Stage IV Major Salivary Gland Cancer AJCC v7\|Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7\|Stage IVA Laryngeal Verrucous Carcinoma AJCC v7\|Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7\|Stage IVA Major Salivary Gland Cancer AJCC v7\|Stage IVA Oral Cavity Cancer AJCC v6 and v7\|Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7\|Stage IVA Sinonasal Squamous Cell Carcinoma AJCC v7\|Stage IVB Laryngeal Squamous Cell Carcinoma AJCC v7\|Stage IVB Laryngeal Verrucous Carcinoma AJCC v7\|Stage IVB Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7\|Stage IVB Major Salivary Gland Cancer AJCC v7\|Stage IVB Oral Cavity Cancer AJCC v6 and v7\|Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7\|Stage IVB Sinonasal Squamous Cell Carcinoma AJCC v7\|Stage IVC Laryngeal Squamous Cell Carcinoma AJCC v7\|Stage IVC Laryngeal Verrucous Carcinoma AJCC v7\|Stage IVC Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7\|Stage IVC Major Salivary Gland Cancer AJCC v7\|Stage IVC Oral Cavity Cancer AJCC v6 and v7\|Stage IVC Oropharyngeal Squamous Cell Carcinoma AJCC v7\|Stage IVC Sinonasal Squamous Cell Carcinoma AJCC v7\|Tongue Carcinoma	August 8, 2008	Phase 3
NCT01007552	Roswell Park Cancer Institute\|Genentech, Inc.	Cholangiocarcinoma	December 2009	Phase 2
NCT00301964	National Cancer Institute (NCI)\|Gynecologic Oncology Group	Recurrent Endometrial Carcinoma	March 2006	Phase 2
NCT01442935	UNICANCER	Colorectal Cancer	February 2011	Phase 2
NCT02079519	Hoffmann-La Roche	Multiple Myeloma	May 2006	Phase 2
NCT04788381	Second Affiliated Hospital, School of Medicine, Zhejiang University	Colorectal Cancer\|Lung Cancer\|Operation Wound; Infection\|Bevacizumab	April 1, 2021
NCT05211323	National Cancer Institute (NCI)	Combined Hepatocellular Carcinoma and Cholangiocarcinoma\|Stage III Liver Cancer\|Stage IV Liver Cancer	February 11, 2022	Phase 2
NCT03844074	Outlook Therapeutics, Inc.	Age-related Macular Degeneration\|Neovascular Age-related Macular Degeneration\|Wet Macular Degeneration	October 1, 2018	Phase 3
NCT01633970	Genentech, Inc.	Cancer	July 11, 2012	Phase 1
NCT00337207	Northwestern University\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors	March 2006	Phase 2
NCT05063552	National Cancer Institute (NCI)	Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8\|Metastatic Head and Neck Squamous Cell Carcinoma\|Metastatic Hypopharyngeal Squamous Cell Carcinoma\|Metastatic Laryngeal Squamous Cell Carcinoma\|Metastatic Lip and Oral Cavity Carcinoma\|Metastatic Nasal Cavity Squamous Cell Carcinoma\|Metastatic Nasopharyngeal Squamous Cell Carcinoma\|Metastatic Pharyngeal Squamous Cell Carcinoma\|Metastatic Sinonasal Squamous Cell Carcinoma\|Recurrent Head and Neck Squamous Cell Carcinoma\|Recurrent Hypopharyngeal Squamous Cell Carcinoma\|Recurrent Laryngeal Squamous Cell Carcinoma\|Recurrent Lip and Oral Cavity Squamous Cell Carcinoma\|Recurrent Nasopharyngeal Squamous Cell Carcinoma\|Recurrent Pharyngeal Squamous Cell Carcinoma\|Recurrent Sinonasal Squamous Cell Carcinoma\|Stage IV Hypopharyngeal Carcinoma AJCC v8\|Stage IV Laryngeal Cancer AJCC v8\|Stage IV Lip and Oral Cavity Cancer AJCC v8\|Stage IV Nasopharyngeal Carcinoma AJCC v8\|Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8\|Stage IV Sinonasal Cancer AJCC v8	December 16, 2021	Phase 2\|Phase 3
NCT03793400	Changhua Christian Hospital	Choroidal Neovascularization\|Punctate Inner Choroidopathy	March 13, 2018
NCT03896074	Fondazione Ricerca Traslazionale	Non-small-cell Lung Cancer Patients	May 2019	Phase 2
NCT00866723	Beth Israel Deaconess Medical Center\|Dana-Farber Cancer Institute\|Massachusetts General Hospital\|Genentech, Inc.	Ovarian Cancer\|Primary Peritoneal Serous Cancer\|Fallopian Tube Cancer	March 2009	Phase 2
NCT00856180	Dana-Farber Cancer Institute\|Massachusetts General Hospital\|Brigham and Women´s Hospital\|Genentech, Inc.	Ovarian Cancer\|Peritoneal Cancer\|Fallopian Tube Cancer	February 2009	Phase 2
NCT00796757	Hoffmann-La Roche	Renal Cell Cancer	December 2008	Phase 2
NCT00999791	Shahid Beheshti University of Medical Sciences	Diffuse Diabetic Macular Edema	July 2009	Phase 1
NCT00698516	GlaxoSmithKline	Recurrent Small-cell Lung Cancer (SCLC)\|Lung Cancer, Small Cell	July 2008	Phase 2
NCT00929058	Radboud University Medical Center	Hypertension\|Cancer	June 2009	Not Applicable
NCT02613208	Hoffmann-La Roche	Breast Cancer	December 9, 2015
NCT01309451	Maturi, Raj K., M.D., P.C.	Diabetic Macular Edema	March 2011	Phase 4
NCT01344824	UNC Lineberger Comprehensive Cancer Center\|National Cancer Institute (NCI)	Lung Cancer	March 2010	Phase 2
NCT01220154	David O´Malley\|Genentech, Inc.\|Ohio State University Comprehensive Cancer Center	Ovarian Cancer\|Fallopian Tube Cancer\|Primary Peritoneal Cancer\|No Prior Chemotherapy	October 2010	Phase 1
NCT00970970	University Medical Center Groningen\|VHL Alliance	Von Hippel-Lindau Disease\|Hemangioblastoma\|Renal Cell Carcinoma\|Pheochromocytoma\|Pancreatic Neuroendocrine Tumor	September 2009
NCT00949247	Case Comprehensive Cancer Center	Breast Cancer	December 2009	Early Phase 1
NCT00532909	Branimir Sikic\|AstraZeneca\|Stanford University	Anal, Colon, and Rectal Cancers\|Colorectal Neoplasms\|Colon+Rectal Cancer	July 2006	Phase 1
NCT02048540	Chinese PLA General Hospital	Locally Advanced Gastric Carcinoma	February 2009	Phase 1\|Phase 2
NCT02054052	Haihong Yang, MD, Pricipal investigator\|Guangzhou Medical University	Non-small Cell Lung Cancer\|Malignant Pleural Effusion	January 2014	Phase 2
NCT01661946	Queen´s University\|The Physicians´ Services Incorporated Foundation	Diabetic Macular Edema	August 2012	Phase 3
NCT04670978	Shandong University	Objective Response Rate	March 31, 2021	Phase 2
NCT02829931	H. Lee Moffitt Cancer Center and Research Institute	Malignant Glioma	August 22, 2016	Phase 1
NCT01504724	Kyungpook National University Hospital	Diabetic Retinopathy	August 2011	Phase 4
NCT02633189	National Cancer Institute, Naples	Non-squamous Non-small Cell Lung Cancer	April 2016	Phase 3
NCT01966913	Assistance Publique - Hôpitaux de Paris	Germ Cell Tumor	April 2012	Phase 1\|Phase 2
NCT04812002	Women´s Hospital School Of Medicine Zhejiang University	Gestational Trophoblastic Neoplasia	April 15, 2021	Phase 2
NCT01894061	Case Comprehensive Cancer Center\|NovoCure Ltd.\|National Cancer Institute (NCI)	Adult Giant Cell Glioblastoma\|Adult Glioblastoma\|Adult Gliosarcoma\|Recurrent Adult Brain Tumor	June 12, 2013	Phase 2
NCT02366143	Hoffmann-La Roche	Carcinoma, Non-Small-Cell Lung	March 31, 2015	Phase 3
NCT00120172	Geriatric Oncology Consortium\|Sanofi	Colorectal Cancer\|Neoplasm Metastasis	May 2005	Phase 2
NCT01260506	Vascular Biogenics Ltd. operating as VBL Therapeutics	Glioblastoma Multiforme	December 2010	Phase 1\|Phase 2
NCT01679327	Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Colorectal Cancer	March 2012	Phase 2
NCT02399410	University Hospital, Ghent	Colorectal Neoplasms	December 2015	Phase 2
NCT01195298	South Eastern European Research Oncology Group\|Roche Pharma AG	Breast Cancer\|Metastasis	May 2010	Phase 2
NCT02985619	University of Sao Paulo	Diabetic Macular Edema	July 21, 2016	Phase 2\|Phase 3
NCT04425681	Second Affiliated Hospital of Nanchang University\|Nanchang University	Leptomeningeal Metastasis\|Non-small Cell Lung Cancer\|EGFR Activating Mutation	October 1, 2017	Phase 2
NCT02848443	Institut de Recherches Internationales Servier\|ADIR, a Servier Group company\|Servier	Metastatic Colorectal Cancer	May 2016	Phase 1
NCT00850577	Bristol-Myers Squibb	Non-small Cell Lung Cancer (NSCLC)	June 2009	Phase 2
NCT00820547	UNICANCER	Breast Cancer	January 2009	Phase 2
NCT01936974	Western Regional Medical Center	Ovarian Carcinoma\|Fallopian Tube Carcinoma\|Peritoneal Carcinoma	September 2013	Phase 2
NCT03353831	AGO Research GmbH\|Hoffmann-La Roche	Recurrent Ovarian Carcinoma	September 11, 2018	Phase 3
NCT00091026	National Cancer Institute (NCI)	Adenocarcinoma of the Pancreas\|Recurrent Pancreatic Cancer\|Stage II Pancreatic Cancer\|Stage III Pancreatic Cancer\|Stage IV Pancreatic Cancer	July 2004	Phase 2
NCT00392392	SCRI Development Innovations, LLC\|Celgene Corporation\|Genentech, Inc.	Breast Cancer	October 2006	Phase 2
NCT01402531	University of California, San Diego	Hereditary Hemorrhagic Telangiectasia (HHT)	July 22, 2010	Phase 2
NCT00043004	European Organisation for Research and Treatment of Cancer - EORTC\|Arbeitsgruppe Lebermetastasen und Tumoren\|Institute of Cancer Research, United Kingdom	Colorectal Cancer\|Metastatic Cancer	May 2002	Phase 2
NCT00588666	Memorial Sloan Kettering Cancer Center	Myeloproliferative Disorder\|Urothelial Carcinoma\|Cancer	May 2006	Phase 2
NCT02806817	Centro Nacional de Investigaciones Oncologicas CARLOS III\|Fundacion CRIS de Investigación para Vencer el Cáncer	Breast Cancer\|Human Epidermal Growth Factor 2 Negative Carcinoma of Breast\|Early-Stage Breast Carcinoma	July 2016	Early Phase 1
NCT04787289	British Columbia Cancer Agency	Ovarian Cancer\|Platinum-resistant Ovarian Cancer	September 2021	Phase 2
NCT00433511	National Cancer Institute (NCI)\|Cancer and Leukemia Group B\|Eastern Cooperative Oncology Group\|North Central Cancer Treatment Group	Breast Adenocarcinoma	November 2, 2007	Phase 3
NCT00418093	Dana-Farber Cancer Institute\|Massachusetts General Hospital\|Brigham and Women´s Hospital\|Eli Lilly and Company\|Sanofi-Synthelabo\|Genentech, Inc.	Ovarian Cancer\|Fallopian Tube Cancer\|Primary Peritoneal Cancer	September 2006	Phase 2
NCT00069095	Hoffmann-La Roche	Colorectal Cancer	July 2003	Phase 3
NCT00517595	Accelerated Community Oncology Research Network\|Eli Lilly and Company\|Genentech, Inc.	Non-Small Cell Lung Cancer	August 2007	Phase 2
NCT05357417	Henan Cancer Hospital	Breast Cancer	April 29, 2022	Phase 2
NCT00408772	University of California, Davis\|Sanofi	Colorectal Cancer\|Metastatic Cancer	June 2007	Phase 2
NCT01137968	Geron Corporation	Non-small Cell Lung Cancer	May 2010	Phase 2
NCT02039674	Merck Sharp & Dohme LLC	Non-small Cell Lung Carcinoma	February 21, 2014	Phase 1\|Phase 2
NCT00870636	Children´s Hospital Los Angeles	Retinopathy of Prematurity
NCT00446030	Sanofi	Breast Neoplasms	March 2007	Phase 2
NCT00127036	H. Lee Moffitt Cancer Center and Research Institute\|Roche Pharma AG	Adenocarcinoma\|Colon Cancer	October 2003	Phase 2
NCT00444535	Novartis Pharmaceuticals\|Novartis	Neoplasms, Breast	February 27, 2007	Phase 2
NCT00369122	National Cancer Institute (NCI)\|Radiation Therapy Oncology Group	Cervical Adenocarcinoma\|Cervical Adenosquamous Carcinoma\|Cervical Squamous Cell Carcinoma, Not Otherwise Specified\|Stage IB Cervical Cancer AJCC v6 and v7\|Stage IIA Cervical Cancer AJCC v7\|Stage IIB Cervical Cancer AJCC v6 and v7\|Stage III Cervical Cancer AJCC v6 and v7	August 11, 2006	Phase 2
NCT01312376	Abramson Cancer Center of the University of Pennsylvania	Ovarian Carcinoma\|Fallopian Tube Cancer\|Primary Peritoneal Cancer	March 2011	Phase 1
NCT02754362	NYU Langone Health\|MOUNT SINAI HOSPITAL	Glioblastoma\|Glioma	November 2016	Phase 2
NCT02982694	Vall d´Hebron Institute of Oncology\|European Organisation for Research and Treatment of Cancer - EORTC	MSI\|ColoRectal Cancer\|Chemotherapy\|Resistance, APC	November 24, 2017	Phase 2
NCT02954172	Innovent Biologics (Suzhou) Co. Ltd.\|WuXi CDS Clinical Research (Shanghai) Co.Ltd.	NSCLC	November 28, 2016	Phase 3
NCT00923936	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Sarcoma, Kaposi	April 23, 2009	Phase 2
NCT01163396	Gruppo Oncologico del Nord-Ovest	Colorectal Cancer Metastatic	July 2007	Phase 2
NCT01782976	M.D. Anderson Cancer Center\|Brain Tumor Trials Collaborative\|EMD Serono	Glioblastoma	June 2013	Phase 2
NCT00343291	Eli Lilly and Company	Non-Small Cell Lung Cancer	December 2006	Phase 2
NCT02106520	Hospices Civils de Lyon	Hereditary Hemorrhagic Telangiectasia\|Epistaxis	April 2014	Phase 2\|Phase 3
NCT01280643	Fox Chase Cancer Center\|National Cancer Institute (NCI)	Metastatic Colorectal Cancer	March 2010	Not Applicable
NCT00601926	Paul Monk\|Genentech, Inc.\|Ohio State University Comprehensive Cancer Center	Kidney Cancer	February 2008	Phase 2
NCT00072566	National Cancer Institute (NCI)	Primary Peritoneal Carcinoma\|Recurrent Ovarian Carcinoma\|Stage IV Ovarian Cancer	December 2003	Phase 2
NCT01266031	National Cancer Institute (NCI)\|M.D. Anderson Cancer Center\|Genentech, Inc.\|Merck Sharp & Dohme LLC\|Brain Tumor Trials Collaborative\|Ohio State University Wexner Medical Center\|Northwestern University Feinberg School of Medicine\|UF Health Cancer Center at Orlando Health\|Baylor Health Care System\|MUSC Hollings Cancer Center\|University of Utah Health System\|University of Washington\|Henry Ford Health System\|Columbia University\|Rush University Medical Center\|NorthShore University HealthSystem\|The Cleveland Clinic\|University of North Carolina, Chapel Hill\|Washington University School of Medicine\|Texas Oncology-Austin\|National Institutes of Health Clinical Center (CC)	Malignant Glioma\|Recurrent Glioblastoma	July 12, 2011	Phase 1\|Phase 2
NCT03127124	NantPharma, LLC	Pancreatic Adenocarcinoma Metastatic	February 27, 2018	Phase 1\|Phase 2
NCT04188145	Centre Hospitalier Universitaire Dijon	Metastatic Colorectal Cancer	January 27, 2020	Phase 3
NCT00393094	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	High-Grade Gliomas	September 2006	Phase 2
NCT00608972	Rutgers, The State University of New Jersey\|Rutgers Cancer Institute of New Jersey\|National Cancer Institute (NCI)	Metastatic Breast Cancer	May 2008	Phase 2
NCT00651482	Sandy Srinivas\|Genentech, Inc.\|Novartis\|Stanford University	Kidney Neoplasms\|Kidney (Renal Cell) Cancer	August 2008	Phase 2
NCT01264341	Hellenic Cooperative Oncology Group	Kidney Cancer	December 2010	Phase 2
NCT02054078	Tang-Du Hospital	Malignant Pleural Effusion	January 2012	Phase 2
NCT01564914	Tracon Pharmaceuticals Inc.\|The Cleveland Clinic\|Case Comprehensive Cancer Center	Glioblastoma\|Glioblastoma Multiforme	May 2012	Phase 2
NCT00484939	Hoffmann-La Roche	Colorectal Cancer	July 2007	Phase 3
NCT02013830	Hoffmann-La Roche	Liver Cancer	May 2005	Phase 2
NCT00483834	University Health Network, Toronto\|Hoffmann-La Roche	Colorectal Cancer	December 2006	Phase 2
NCT00165568	Dana-Farber Cancer Institute\|Massachusetts General Hospital\|Brigham and Women´s Hospital	Colorectal Cancer\|Neoplasm Metastasis	July 2005	Phase 2
NCT00702819	Vision Research Foundation	Retinopathy of Prematurity	June 2008	Phase 1
NCT00370669	Shahid Beheshti University of Medical Sciences	Diabetic Macular Edema	November 2005	Phase 3
NCT00523809	M.D. Anderson Cancer Center	Breast Cancer\|Ovarian Cancer	August 2007	Phase 2
NCT03395899	Queen Mary University of London\|Kliniken Essen-Mitte\|MedSIR\|Asan Medical Center\|Hoffmann-La Roche	Breast Cancer\|Estrogen Receptor-positive Breast Cancer	December 21, 2017	Phase 2
NCT05491811	Sun Yat-sen University\|First Affiliated Hospital of Wenzhou Medical University\|Second Affiliated Hospital, School of Medicine, Zhejiang University\|Liaoning Cancer Hospital & Institute\|Shenyang Chest Hospital\|Harbin Medical University\|Hebei Medical University Fourth Hospital\|Handan Central Hospital\|The First Affiliated Hospital of Soochow University\|Jiangsu Cancer Institute & Hospital\|The First Affiliated Hospital with Nanjing Medical University\|Huai´an First People´s Hospital\|Wuhan Union Hospital, China	Non-Small Cell Lung Cancer	August 2022	Phase 2
NCT04516278	Outlook Therapeutics, Inc.	Age-related Macular Degeneration\|Neovascular Age-related Macular Degeneration\|Wet Macular Degeneration\|BRVO - Branch Retinal Vein Occlusion\|Diabetic Macular Edema	October 1, 2020	Phase 3
NCT03905317	Sun Yat-sen University	Lung Adenocarcinoma	March 1, 2019	Phase 2
NCT03925662	Sherief Abd-Elsalam\|Tanta University	Colorectal Cancer	April 1, 2019	Phase 3
NCT00811993	Hoffmann-La Roche	Neoplasms	February 2009	Phase 1
NCT00555594	Asociación para Evitar la Ceguera en México\|National Council of Science and Technology, Mexico\|Universidad Nacional Autonoma de Mexico	Corneal Neovascularization	September 2006	Phase 2\|Phase 3
NCT03792074	Sinocelltech Ltd.	Non-squamous Cell Non-small Cell Lung Cancer	February 2019	Phase 3
NCT05377034	National Cancer Centre, Singapore\|Hoffmann-La Roche\|Sirtex Medical\|Singapore Clinical Research Institute	Locally Advanced Hepatocellular Carcinoma	August 25, 2022	Phase 2
NCT01918852	Dutch Colorectal Cancer Group\|Nordic Pharma SAS	Colorectal Cancer\|Metastases	December 2013	Phase 3
NCT00483782	Medical Research Council\|National Cancer Institute (NCI)	Fallopian Tube Cancer\|Ovarian Cancer\|Primary Peritoneal Cavity Cancer	April 2006	Phase 3
NCT03708536	Fujian Cancer Hospital	Colorectal Adenocarcinoma	November 2018	Phase 3
NCT03686254	Nanfang Hospital of Southern Medical University	Colorectal Neoplasms Malignant	July 16, 2018	Phase 2\|Phase 3
NCT01690325	West German Study Group\|Roche Pharma AG\|Sanofi	Breast Cancer	September 2012	Phase 2
NCT00611325	Duke University\|Millennium Pharmaceuticals, Inc.\|Genentech, Inc.	Glioblastoma\|Gliosarcoma	May 2008	Phase 2
NCT02645734	Shahid Beheshti University of Medical Sciences	Diabetic Macular Edema		Phase 2\|Phase 3
NCT00055861	National Cancer Institute (NCI)	Recurrent Breast Cancer\|Stage IV Breast Cancer	July 2002	Phase 2
NCT01295944	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Ependymoma\|Anaplastic Ependymoma	April 27, 2011	Phase 2
NCT00394251	Celgene	Breast Cancer	August 1, 2006	Phase 2
NCT02974621	National Cancer Institute (NCI)	Recurrent Glioblastoma	September 15, 2017	Phase 2
NCT00296816	Sanofi	Ovarian Cancer	March 2006	Phase 2
NCT00022659	National Cancer Institute (NCI)\|Gynecologic Oncology Group	Primary Peritoneal Cavity Cancer\|Recurrent Ovarian Epithelial Cancer\|Stage IV Ovarian Epithelial Cancer	April 2002	Phase 2
NCT02724878	Dana-Farber Cancer Institute\|Genentech, Inc.	Advanced Non-Clear Cell Kidney Cancer	July 2016	Phase 2
NCT00892177	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Glioblastoma Multiforme	October 2009	Phase 2
NCT01207687	National Cancer Institute (NCI)	Vestibular Schwannoma\|Neurofibromatosis Type 2	October 2010	Phase 2
NCT00121836	Hoffmann-La Roche	Breast Cancer	June 2005	Phase 4
NCT01625936	Abramson Cancer Center of the University of Pennsylvania	Renal Cell Carcinoma	June 2012	Phase 1
NCT05482516	Georgetown University\|Genentech, Inc.\|Natera, Inc.	Colon Adenocarcinoma\|Rectal Adenocarcinoma\|Gastric Adenocarcinoma\|Pancreatic Adenocarcinoma\|Hepatocellular Carcinoma\|Adenocarcinoma of Biliary Tract\|Gallbladder Adenocarcinoma	December 2022	Phase 3
NCT00115765	Amgen	Colorectal Cancer	June 1, 2005	Phase 3
NCT01626339	University of Malaya	Age Related Macular Degeneration	April 2012	Not Applicable
NCT00993044	Children´s Hospital Los Angeles	Refractory Solid Tumors in Children	September 2009	Phase 1
NCT00085358	National Cancer Institute (NCI)\|Gynecologic Oncology Group	Brenner Tumor\|Fallopian Tube Cancer\|Ovarian Carcinosarcoma\|Ovarian Clear Cell Cystadenocarcinoma\|Ovarian Endometrioid Adenocarcinoma\|Ovarian Mixed Epithelial Carcinoma\|Ovarian Mucinous Cystadenocarcinoma\|Ovarian Serous Cystadenocarcinoma\|Ovarian Undifferentiated Adenocarcinoma\|Primary Peritoneal Cavity Cancer\|Stage II Ovarian Epithelial Cancer\|Stage III Ovarian Epithelial Cancer\|Stage IV Ovarian Epithelial Cancer	May 2004	Phase 1
NCT00557232	Instituto de Olhos de Goiania	Glaucoma\|Rubeosis Iridis	November 2006	Phase 4
NCT00347698	Asociación para Evitar la Ceguera en México	Diabetic Retinopathy	March 2006	Phase 2\|Phase 3
NCT04739670	Peter MacCallum Cancer Centre, Australia	Metastatic Triple Negative Breast Cancer	March 1, 2021	Phase 2
NCT00023920	National Cancer Institute (NCI)	Blastic Phase Chronic Myelogenous Leukemia\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive	July 2001	Phase 2
NCT00996502	Columbia University\|Genentech, Inc.	Prostate Cancer	July 2006	Phase 1\|Phase 2
NCT05141721	Gritstone bio, Inc.	Colorectal Neoplasms	February 12, 2022	Phase 2\|Phase 3
NCT00466687	Vanderbilt-Ingram Cancer Center\|National Cancer Institute (NCI)	Melanoma	September 2004	Phase 2
NCT00845910	Hoffmann-La Roche	Breast Cancer	May 2009	Phase 2
NCT01468831	National Eye Institute (NEI)\|National Institutes of Health Clinical Center (CC)	Retinal Vein Occlusion	March 28, 2012	Phase 1\|Phase 2
NCT03642132	Pfizer	Ovarian Cancer	July 19, 2018	Phase 3
NCT00600821	Pfizer	Non-Small-Cell Lung Carcinoma\|Adenocarcinoma	April 2008	Phase 2
NCT00817284	Ulrik Lassen\|Rigshospitalet, Denmark	Glioblastoma Multiforme	November 2008	Phase 2
NCT00623805	Hoffmann-La Roche	Colorectal Cancer	March 2008	Phase 3
NCT00366457	Massachusetts General Hospital\|Genentech, Inc.\|Beth Israel Deaconess Medical Center\|Dana-Farber Cancer Institute	Pancreatic Cancer\|Adenocarcinoma of the Pancreas	August 2006	Phase 2
NCT00955305	National Cancer Institute (NCI)	Large Cell Lung Carcinoma\|Lung Adenocarcinoma\|Recurrent Non-Small Cell Lung Carcinoma\|Stage IV Non-Small Cell Lung Cancer\|Bronchioloalveolar Lung Carcinoma	March 2010	Phase 2
NCT01004250	Eli Lilly and Company	Non-Small Cell Lung Cancer	October 2009	Phase 2
NCT01739218	Hoffmann-La Roche	Ovarian Cancer	February 1, 2013	Phase 2
NCT00941499	M.D. Anderson Cancer Center	Advanced Cancers	July 2009	Phase 1
NCT00556088	SCRI Development Innovations, LLC\|Novartis	Solid Tumors	December 2007	Phase 1
NCT01383343	National Cancer Institute (NCI)	Recurrent Colon Carcinoma\|Recurrent Rectal Carcinoma\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer	August 2011	Phase 1
NCT03030430	Bio-Thera Solutions	NSCLC	March 15, 2016	Phase 1
NCT00200200	Memorial Sloan Kettering Cancer Center	Hepatic Metastases\|Colon Cancer\|Rectal Cancer	November 19, 2004	Phase 2
NCT05528952	Centre Hospitalier Universitaire de Besancon\|GERCOR - Multidisciplinary Oncology Cooperative Group	Hepatocellular Carcinoma	September 27, 2022	Phase 2
NCT00347399	Asociación para Evitar la Ceguera en México	Age Related Macular Degeneration	March 2006	Phase 2
NCT02612077	Hoffmann-La Roche	Metastatic Colorectal Cancer	May 2008
NCT04741165	Taizhou Hanzhong biomedical co. LTD	Hepatocellular Carcinoma	January 7, 2021	Phase 2
NCT00883298	Center for Neurosciences, Tucson\|Genentech, Inc.	Recurrent Glioblastoma Multiforme\|Recurrent Gliosarcoma	April 2009	Phase 2
NCT00755170	Hellenic Oncology Research Group\|University Hospital of Crete	Non Small Cell Lung Cancer	November 2008	Phase 2
NCT01027468	Medical University of Vienna	Neovascular Age-related Macular Degeneration	August 2009	Not Applicable
NCT00929240	Hoffmann-La Roche	Breast Cancer	July 2009	Phase 3
NCT00569127	National Cancer Institute (NCI)	Atypical Carcinoid Tumor\|Carcinoid Tumor\|Colorectal Neuroendocrine Tumor G1\|Gastric Neuroendocrine Tumor G1\|Neuroendocrine Neoplasm	December 1, 2007	Phase 3
NCT03390673	Prestige Biopharma Limited	Healthy Volunteers	September 19, 2018	Phase 1
NCT05427305	TOT Biopharm Co., Ltd.	Efficacy	October 20, 2017	Phase 3
NCT00703235	Isfahan Ophthalmology Research Center	Macular Edema\|Diabetic Retinopathy		Phase 2\|Phase 3
NCT00100815	Roswell Park Cancer Institute	Pancreatic Cancer	August 2004	Phase 2
NCT04743661	Pediatric Brain Tumor Consortium\|National Cancer Institute (NCI)\|Memorial Sloan Kettering Cancer Center\|Y-mAbs Therapeutics, Inc	Recurrent Medulloblastoma\|Recurrent Ependymoma	April 4, 2022	Phase 2
NCT03611179	Nada Hassan Salah\|Assiut University	Advanced Ovarian Cancer	September 1, 2018	Phase 2
NCT03635567	Merck Sharp & Dohme LLC	Cervical Cancer	October 25, 2018	Phase 3
NCT01674738	Aktion Bronchialkarzinom e.V.\|Roche Pharma AG\|Eli Lilly and Company	Carcinoma, Non-Small-Cell Lung		Phase 2
NCT00862342	Asan Medical Center	Metastatic Colorectal Cancer	January 2009	Phase 2
NCT00565656	Centre Hospitalier Universitaire de Nice	Myelodysplastic Syndromes	July 2007	Phase 2
NCT00371111	Shahid Beheshti University of Medical Sciences	Resistant Cystoid Macular Edema	August 2006	Phase 1
NCT00349336	Hoffmann-La Roche	Colorectal Cancer	August 2006	Phase 3
NCT00740168	Technische Universität Dresden	Cancer	May 2007
NCT04735861	Tongji Hospital\|Union Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology\|Qilu Hospital of Shandong University\|The First Affiliated Hospital of Zhengzhou University\|Henan Cancer Hospital\|Hubei Cancer Hospital\|Shengjing Hospital\|Anhui Provincial Cancer Hospital\|Wuhan University\|Jingzhou Central Hospital\|The First People´s Hospital of Jingzhou\|Xiangyang Central Hospital	Ovarian Clear Cell Carcinoma	April 7, 2021	Phase 2
NCT02141295	Hoffmann-La Roche	Colorectal Cancer	June 30, 2014	Phase 2
NCT00802906	Johann Wolfgang Goethe University Hospital	Central Serous Chorioretinopathy	May 2007	Not Applicable
NCT02997228	National Cancer Institute (NCI)\|NRG Oncology	Metastatic Colorectal Adenocarcinoma\|Stage IV Colorectal Cancer AJCC v7\|Stage IVA Colorectal Cancer AJCC v7\|Stage IVB Colorectal Cancer AJCC v7	November 7, 2017	Phase 3
NCT03498521	Hoffmann-La Roche\|Foundation Medicine, Inc.	Cancer of Unknown Primary Site	July 10, 2018	Phase 2
NCT05330429	Gilead Sciences	Metastatic Colorectal Cancer	July 8, 2022	Phase 2
NCT01999270	Washington University School of Medicine	Astrocytoma, Oligoastrocytoma, Mixed\|Ganglioneuroma\|Glioma\|Ganglioglioma\|Glioblastoma Multiforme Glioma	April 2013	Phase 1
NCT01649947	Rutgers, The State University of New Jersey\|National Cancer Institute (NCI)\|Rutgers Cancer Institute of New Jersey	Non-small Cell Lung Cancer\|Advanced Non-small Cell Lung Cancer\|Recurrent Non-small Cell Lung Cancer	December 23, 2011	Phase 2
NCT00543842	M.D. Anderson Cancer Center\|Genentech, Inc.	Rectal Cancer	December 2007	Phase 1
NCT00360360	SCRI Development Innovations, LLC\|Genentech, Inc.	Neoplasm, Unknown Primary	July 2006	Phase 2
NCT03526432	University of Oklahoma\|Genentech, Inc.	Endometrial Cancer	August 8, 2018	Phase 2
NCT03428958	NuCana plc	Colorectal Cancer\|Colorectal Neoplasms\|Colorectal Carcinoma\|Colorectal Tumors\|Neoplasms, Colorectal	October 16, 2018	Phase 1\|Phase 2
NCT00511992	University of Oklahoma\|Genentech, Inc.	Advanced Ovarian Carcinoma\|Primary Peritoneal Carcinoma\|Ovarian Carcinosarcoma	July 2007	Phase 2
NCT05382442	Akeso	Metastatic Colorectal Cancer	July 27, 2022	Phase 2
NCT03396926	University of California, San Francisco\|Merck Sharp & Dohme LLC	Microsatellite Stable\|Mismatch Repair Protein Proficient\|Stage III Colorectal Cancer AJCC v7\|Stage IIIB Colorectal Cancer AJCC v7\|Stage IIIC Colorectal Cancer AJCC v7\|Stage IV Colorectal Cancer AJCC v7\|Stage IVA Colorectal Cancer AJCC v7\|Stage IVB Colorectal Cancer AJCC v7	April 18, 2018	Phase 2
NCT01743157	California Pacific Medical Center Research Institute	Metastatic Melanoma	December 2010	Phase 1\|Phase 2
NCT03126799	National Cancer Center, Korea\|Roche Korea co.,Ltd.	EGFR Positive Non-small Cell Lung Cancer	November 1, 2016	Phase 2
NCT00853021	Jorge A. Garcia, MD\|National Cancer Institute (NCI)\|Case Comprehensive Cancer Center	Kidney Cancer	December 2005	Phase 2
NCT01641406	Auxilio Mutuo Cancer Center	Infiltrating Duct and Lobular Carcinoma In Situ\|Invasive Lobular Breast Carcinoma\|Inflammatory Breast Carcinoma	March 2011	Phase 2
NCT01142778	Hoffmann-La Roche	Breast Cancer	May 19, 2010	Phase 2
NCT00028990	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)\|North Central Cancer Treatment Group\|NCIC Clinical Trials Group\|NSABP Foundation Inc	Breast Cancer	December 2001	Phase 3
NCT00096967	Genentech, Inc.	Breast Cancer\|Colorectal Cancer\|Metastases	October 2002	Phase 3
NCT00507585	M.D. Anderson Cancer Center	Liver Cancer\|Advanced Solid Tumors	June 2006	Phase 1
NCT01198548	Roswell Park Cancer Institute\|National Cancer Institute (NCI)	Stage IV Colon Cancer\|Stage IV Rectal Cancer	August 2010	Phase 2
NCT05314101	Fujian Cancer Hospital	Immunotherapy\|Colorectal Cancer	April 1, 2022	Phase 2
NCT03919448	Laboratorios Richmond S.A.C.I.F.\|FP Clinical Pharma S.R.L.\|Syngene International Limited	Pharmacokinetics\|Safety Issues	April 1, 2019	Phase 1
NCT01217437	National Cancer Institute (NCI)	Central Nervous System Neoplasm\|Pineoblastoma\|Recurrent Medulloblastoma\|Recurrent Primitive Neuroectodermal Tumor\|Refractory Medulloblastoma\|Refractory Peripheral Primitive Neuroectodermal Tumor	November 22, 2010	Phase 2
NCT05510427	M.D. Anderson Cancer Center\|Helsinn Healthcare	Cholangiocarcinoma\|Liver Cancer	February 28, 2023	Phase 1
NCT00137813	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital\|Beth Israel Deaconess Medical Center\|Genentech, Inc.\|Sanofi	Esophageal Cancer\|Gastric Cancer	August 2004	Phase 2
NCT04732598	Japanese Foundation for Cancer Research\|Chugai Pharmaceutical	Breast Cancer	January 21, 2021	Phase 3
NCT04344782	Assistance Publique - Hôpitaux de Paris	COVID19 Pneumonia	April 15, 2020	Phase 2
NCT03991403	Samsung Medical Center	Non-small Cell Lung Cancer	August 27, 2019	Phase 3
NCT00612430	Duke University\|Genentech, Inc.	Glioblastoma\|Gliosarcoma	March 2007	Phase 2
NCT04677504	Hoffmann-La Roche	Biliary Tract Cancer	February 23, 2021	Phase 2
NCT02796183	Neon Hospital\|Ondokuz May?s University	Diabetic Macular Edema	January 2015	Not Applicable
NCT05512351	Henan Provincial People´s Hospital	Oligodendroglioma	December 23, 2022	Phase 2
NCT03573986	Abramson Cancer Center of the University of Pennsylvania	Recurrent Glioblastoma	April 18, 2018	Phase 1
NCT05009017	Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Biosimilar	January 1, 2021
NCT00126633	University of California, San Francisco\|National Cancer Institute (NCI)	Pancreatic Cancer	April 2004	Phase 2
NCT01364012	Hoffmann-La Roche	Non-Small Cell Lung Cancer	May 23, 2011	Phase 3
NCT00208546	Dutch Colorectal Cancer Group\|Koningin Wilhelmina Fonds\|Sanofi\|Roche Pharma AG\|Immunicon	Colorectal Cancer	June 2005	Phase 3
NCT00548418	Washington University School of Medicine\|GlaxoSmithKline\|Genentech, Inc.	Cervical Cancer	February 2007	Phase 2
NCT00911716	Cancer Trials Ireland	Breast Cancer	October 2008	Not Applicable
NCT01231633	Long Island Vitreoretinal Consultants	Macular Edema\|Central Retinal Vein Occlusion	September 2010	Not Applicable
NCT00665990	St. Jude Children´s Research Hospital	Refractory Solid Tumors\|Leukemia	November 2007	Phase 1
NCT00599820	Asociación para Evitar la Ceguera en México	Angioid Streaks\|Choroidal Neovascularization	November 2005	Phase 3
NCT00544011	Hopital Jean Minjoz\|National Cancer Institute (NCI)	Colorectal Cancer	April 2007	Phase 2
NCT03795311	Centre Georges Francois Leclerc	Colorectal Cancer	November 7, 2018	Phase 1\|Phase 2
NCT00512876	Walter Reed Army Medical Center\|Massachusetts Eye and Ear Infirmary	Corneal Neovascularization	August 2007	Not Applicable
NCT01821859	OHSU Knight Cancer Institute	Ovarian Cancer\|Peritoneal Cancer	January 2010	Phase 2
NCT02138617	UNC Lineberger Comprehensive Cancer Center	Colon Cancer	May 2014	Phase 2
NCT05611645	Huashan Hospital	Glioma\|Recurrent Glioma	October 1, 2022	Phase 2
NCT00972335	SCRI Development Innovations, LLC\|Genentech, Inc.\|Novartis	Intracranial Meningioma	January 2010	Phase 2
NCT00559936	Massachusetts Eye and Ear Infirmary	Corneal Neovascularization	February 2007	Phase 1
NCT03024437	Roberto Pili\|Genentech, Inc.\|Syndax Pharmaceuticals\|Indiana University	Metastatic Cancer\|Renal Cancer	June 29, 2017	Phase 1\|Phase 2
NCT04553510	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Nasopharyngeal Carcinoma\|Adverse Effect of Radiation Therapy\|Brain Injuries	January 1, 2016	Phase 2
NCT05022927	Chugai Pharmaceutical	Hepatocellular Carcinoma (HCC)	June 1, 2021	Phase 1
NCT01954030	Annick Desjardins\|Tactical Therapeutics, Inc.\|Duke University	Malignant Glioma (WHO Grade III or IV)	October 2013	Phase 1
NCT00281840	Case Comprehensive Cancer Center\|National Cancer Institute (NCI)	Head and Neck Cancer	September 2005	Phase 2
NCT04982237	Akeso	Cervical Cancer	August 27, 2021	Phase 3
NCT04406272	Dana-Farber Cancer Institute\|Vascular Biogenics Ltd. operating as VBL Therapeutics	Glioblastoma\|Recurrent Glioblastoma	August 1, 2020	Phase 2
NCT01775644	Hoffmann-La Roche	Colorectal Cancer	December 14, 2012
NCT01496742	Genentech, Inc.	Non-Squamous Non-Small Cell Lung Cancer	April 2012	Phase 2
NCT00109057	Genentech, Inc.	Cancer	February 1998	Phase 2
NCT01167725	Walter Reed Army Medical Center\|National Cancer Institute (NCI)	Colorectal Cancer	August 2010	Phase 3
NCT00580333	Massachusetts General Hospital\|Dana-Farber Cancer Institute\|Beth Israel Deaconess Medical Center\|Brigham and Women´s Hospital\|Genentech, Inc.	Breast Cancer	September 2007	Phase 2
NCT00384176	AstraZeneca	Colorectal Cancer	August 30, 2006	Phase 2\|Phase 3
NCT00887822	Hoffmann-La Roche	Gastric Cancer	March 2009	Phase 3
NCT04034459	Ludwig-Maximilians - University of Munich	Metastatic Colorectal Cancer	November 25, 2016	Phase 2
NCT00674011	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital	Breast Cancer	January 2008
NCT01367028	Austrian Breast & Colorectal Cancer Study Group\|Hoffmann-La Roche\|Cephalon	Breast Cancer	June 2011	Phase 2
NCT00684853	Federal University of São Paulo	Macular Degeneration	November 2007	Phase 2
NCT03762018	ETOP IBCSG Partners Foundation\|Hoffmann-La Roche	Pleural Mesothelioma Malignant Advanced	April 30, 2019	Phase 3
NCT04954014	Maimónides Biomedical Research Institute of Córdoba	ARDS, Human\|Coronavirus Infection	September 1, 2020	Phase 2
NCT01434147	Austrian Breast & Colorectal Cancer Study Group\|Hoffmann-La Roche	Rectal Cancer	October 2011	Phase 2
NCT00468585	Memorial Sloan Kettering Cancer Center	Breast Cancer	June 2005	Phase 1\|Phase 2
NCT00660621	Kentuckiana Cancer Institute\|Eisai Inc.	Glioma	April 2008	Phase 2
NCT00569335	Taiho Pharmaceutical Co., Ltd.	Colorectal, Cancer	October 2007	Phase 2
NCT03869892	Institut de Recherches Internationales Servier\|ADIR, a Servier Group company\|Servier	Metastatic Colorectal Cancer	March 21, 2019	Phase 3
NCT00373256	Pfizer	Breast Neoplasms	November 2006	Phase 3
NCT01314066	Weill Medical College of Cornell University	Severe Sepsis\|Acute Respiratory Distress Syndrome	July 2010	Phase 2
NCT05512325	Henan Provincial People´s Hospital	Genetic Change	December 17, 2022
NCT00847119	Institut Català d´Oncologia\|Hoffmann-La Roche	Rectal Cancer	September 2007	Phase 2
NCT00016094	National Cancer Institute (NCI)	Anaplastic Large Cell Lymphoma\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Mantle Cell Lymphoma	April 2001	Phase 2
NCT00052559	National Cancer Institute (NCI)	Adenocarcinoma of the Rectum\|Stage II Rectal Cancer\|Stage III Rectal Cancer	August 2002	Phase 1
NCT03167177	ImmunityBio, Inc.	Melanoma	December 2017	Phase 1\|Phase 2
NCT03032484	The University of Texas Health Science Center at San Antonio	Astrocytoma	May 18, 2017	Phase 2
NCT00491855	M.D. Anderson Cancer Center	Peritoneal Cancer	June 2007	Phase 1
NCT04931342	Hoffmann-La Roche\|GOG Foundation\|European Network of Gynaecological Oncological Trial Groups (ENGOT)	Ovarian Cancer	October 7, 2021	Phase 2
NCT00733408	University of Washington\|National Cancer Institute (NCI)	Estrogen Receptor-negative Breast Cancer\|HER2-negative Breast Cancer\|Progesterone Receptor-negative Breast Cancer\|Recurrent Breast Cancer\|Stage IV Breast Cancer\|Triple-negative Breast Cancer	April 23, 2008	Phase 2
NCT00550927	Eli Lilly and Company\|National Cancer Institute (NCI)	Unspecified Adult Solid Tumor, Protocol Specific	November 2006	Phase 1
NCT05411757	Shandong Public Health Clinical Center\|Imbioray (Hangzhou) Biomedicine Co., Ltd.	Advanced Primary Liver Cancer	June 30, 2022	Early Phase 1
NCT00520403	Hoffmann-La Roche	Renal Cell Cancer	September 2007	Phase 2
NCT00271505	M.D. Anderson Cancer Center\|Genentech, Inc.	Non-Small Cell Lung Cancer	December 5, 2005	Phase 2
NCT00800917	Rigshospitalet, Denmark\|University of Copenhagen\|Wyeth is now a wholly owned subsidiary of Pfizer\|Roche, Copenhagen	Glioblastoma Multiforme	November 2008	Phase 2
NCT00324870	National Cancer Institute (NCI)	Clear Cell Renal Cell Carcinoma\|Recurrent Renal Cell Cancer\|Stage III Renal Cell Cancer\|Stage IV Renal Cell Cancer	February 2006	Phase 1\|Phase 2
NCT05007106	Merck Sharp & Dohme LLC	Uterine Cervical Neoplasms\|Endometrial Neoplasms\|Squamous Cell Carcinoma of Head and Neck\|Gallbladder Neoplasms\|Cholangiocarcinoma\|Esophageal Neoplasms\|Triple Negative Breast Neoplasms\|Hepatocellular Carcinoma\|Urinary Bladder Neoplasms\|Ovarian Neoplasms\|Stomach Neoplasms	September 16, 2021	Phase 2
NCT04837716	M.D. Anderson Cancer Center	Metastatic Lung Non-Small Cell Carcinoma\|Recurrent Lung Non-Small Cell Carcinoma\|Stage IIIC Lung Cancer AJCC v8\|Stage IV Lung Cancer AJCC v8\|Stage IVA Lung Cancer AJCC v8\|Stage IVB Lung Cancer AJCC v8	March 18, 2021	Phase 1
NCT01787669	University of Sydney\|Allergan	Diabetes\|Diabetic Macular Oedema\|Diabetic Macular Edema\|Diabetic Retinopathy	June 2013	Phase 2
NCT00804830	Region Skane	Thyroid Neoplasms\|Carcinoma\|Thyroid Cancer\|Metastatic Cancer	April 2008	Phase 2
NCT01296815	Centro de Investigación en. Enfermedades Infecciosas, Mexico	Kaposi´s Sarcoma	September 2010	Phase 2
NCT05514925	Khairallah Moncef\|University Hospital Fattouma Bourguiba	Proliferative Diabetic Retinopathy\|Vitreous Hemorrhage\|Tractional Retinal Detachment	November 21, 2017	Phase 4
NCT03668054	Laboratorio Elea Phoenix S.A.	Age-Related Macular Degeneration	February 7, 2017	Phase 3
NCT02753127	Sumitomo Pharma Oncology, Inc.	Colorectal Cancer	June 2016	Phase 3
NCT00954642	Genentech, Inc.	Solid Cancers	August 2009	Phase 1
NCT04564898	Gruppo Oncologico del Nord-Ovest	Colorectal Cancer Metastatic	January 25, 2022	Phase 1\|Phase 2
NCT00548548	Genentech, Inc.\|Hoffmann-La Roche\|Chugai Pharmaceutical	Adenocarcinoma	September 2007	Phase 3
NCT03609307	Shahid Beheshti University of Medical Sciences	Age Related Macular Degeneration	September 2018	Phase 2\|Phase 3
NCT00159432	University of Southern California\|Hoffmann-La Roche\|Genentech, Inc.	Colorectal Cancer	February 2005	Phase 2
NCT00217425	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Lymphoma	July 2006	Phase 2
NCT01437618	Azienda Ospedaliero, Universitaria Pisana	Metastatic Colorectal Cancer	June 2009
NCT00675597	Memorial Sloan Kettering Cancer Center\|Sanofi	Lung Cancer	May 2008	Not Applicable
NCT00700180	Hoffmann-La Roche	Non-Small Cell Lung Cancer	September 2008	Phase 2
NCT01803282	Gilead Sciences	Pancreatic Cancer\|Non-small Cell Lung Cancer\|Esophagogastric Cancer\|Colorectal Cancer\|Breast Cancer	March 29, 2013	Phase 1
NCT00387374	National Cancer Institute (NCI)	Adenosquamous Cell Lung Cancer\|Drug+Agent Toxicity by Tissue+Organ\|Hemoptysis\|Squamous Cell Lung Cancer\|Stage IIIB Non-small Cell Lung Cancer\|Stage IV Non-small Cell Lung Cancer	October 2006	Phase 2
NCT00875147	University of Zurich	Colorectal Liver Metastases	April 2009
NCT02271464	Azienda Ospedaliero, Universitaria Pisana	Metastatic Colorectal Cancer	March 2012	Phase 2
NCT00612339	Duke University\|Genentech, Inc.\|Schering-Plough	Glioblastoma\|Gliosarcoma	August 2007	Phase 2
NCT01186991	Genentech, Inc.\|Hoffmann-La Roche	Breast Cancer	March 2011	Phase 2
NCT01097746	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Fallopian Tube Carcinoma\|Fallopian Tube Clear Cell Adenocarcinoma\|Fallopian Tube Endometrioid Adenocarcinoma\|Fallopian Tube Mucinous Adenocarcinoma\|Fallopian Tube Serous Adenocarcinoma\|Fallopian Tube Transitional Cell Carcinoma\|Fallopian Tube Undifferentiated Carcinoma\|FIGO Stage III Ovarian Cancer\|FIGO Stage IIIA Ovarian Cancer\|FIGO Stage IIIA1 Ovarian Cancer\|FIGO Stage IIIA1(i) Ovarian Cancer\|FIGO Stage IIIA1(ii) Ovarian Cancer\|FIGO Stage IIIA2 Ovarian Cancer\|FIGO Stage IIIB Ovarian Cancer\|FIGO Stage IIIC Ovarian Cancer\|FIGO Stage IVA Ovarian Cancer\|FIGO Stage IVB Ovarian Cancer\|Malignant Ovarian Brenner Tumor\|Ovarian Clear Cell Adenocarcinoma\|Ovarian Endometrioid Adenocarcinoma\|Ovarian Mucinous Adenocarcinoma\|Ovarian Seromucinous Carcinoma\|Ovarian Serous Adenocarcinoma\|Ovarian Transitional Cell Carcinoma\|Ovarian Undifferentiated Carcinoma\|Primary Peritoneal Carcinoma\|Primary Peritoneal Serous Adenocarcinoma	April 14, 2010	Phase 2
NCT01351415	Hoffmann-La Roche	Non-Squamous Non-Small Cell Lung Cancer	June 25, 2011	Phase 3
NCT01532089	Academic and Community Cancer Research United\|National Cancer Institute (NCI)	EGFR Exon 19 Deletion Mutation\|EGFR NP_005219.2:p.L858R\|Lung Non-Squamous Non-Small Cell Carcinoma\|Stage IV Lung Non-Small Cell Cancer AJCC v7	March 16, 2012	Phase 2
NCT02336165	Ludwig Institute for Cancer Research\|MedImmune LLC\|Cancer Research Institute, New York City\|Cure Brain Cancer Foundation, Australia	Glioblastoma	February 26, 2015	Phase 2
NCT00597402	Duke University\|Genentech, Inc.\|Schering-Plough	Glioblastoma\|Gliosarcoma\|Brain Tumor	July 2007	Phase 2
NCT01262859	University of Pittsburgh\|Genentech, Inc.	Head and Neck Neoplasms	December 2010	Phase 2
NCT02076152	Massachusetts General Hospital\|National Cancer Institute (NCI)	Recurrent Glioblastoma	February 2014	Not Applicable
NCT00602602	Abramson Cancer Center of the University of Pennsylvania\|National Cancer Institute (NCI)	Pancreatic Cancer	March 2007	Phase 2
NCT01386710	Northwell Health	Glioblastoma Multiforme\|Anaplastic Astrocytoma	September 2011	Phase 1\|Phase 2
NCT01705184	Intergroupe Francophone de Cancerologie Thoracique	Non-small Cell Lung Cancer Metastatic\|Nonsquamous Nonsmall Cell Neoplasm of Lung	December 2012	Phase 2
NCT01303679	ARCAGY+ GINECO GROUP	First Line Metastatic Breast Cancer	June 2010	Phase 3
NCT02316327	Fundacion Clinic per a la Recerca Biomédica	Non-Small Cell Lung Cancer (NSCLC)	July 2013	Phase 4
NCT00448591	Hoffmann-La Roche	Breast Cancer	September 2006	Phase 3
NCT00943826	Hoffmann-La Roche	Glioblastoma	June 29, 2009	Phase 3
NCT01471470	Asan Medical Center\|Roche Pharma AG	Advanced Gastric Cancer	July 2010	Phase 2
NCT01301716	Genentech, Inc.	Solid Cancers	September 2011	Phase 1
NCT00433927	PD Dr. med. Volker Heinemann\|Merck KGaA, Darmstadt, Germany\|Ludwig-Maximilians - University of Munich	Neoplasm Metastasis\|Colorectal Cancer	January 2007	Phase 3
NCT00826540	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage IV Colon Cancer\|Stage IV Rectal Cancer	September 2009	Phase 2
NCT00070122	National Cancer Institute (NCI)	Adenocarcinoma of the Colon\|Adenocarcinoma of the Rectum\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Stage III Colon Cancer\|Stage III Rectal Cancer\|Stage IV Colon Cancer\|Stage IV Rectal Cancer	April 2004	Phase 3
NCT00242502	M.D. Anderson Cancer Center\|Genentech, Inc.	Hepatocellular Carcinoma\|Liver Cancer	October 2005	Phase 2
NCT00353262	Hoffmann-La Roche	Colorectal Cancer	July 2005	Phase 1
NCT00370851	Shahid Beheshti University of Medical Sciences	Retinal Disease	August 2006	Phase 3
NCT00217581	Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Esophageal Cancer\|Gastric Cancer	October 2004	Phase 2
NCT01473251	Vitreo-Retinal Associates, Michigan\|Van Andel Research Institute	Exudative Macular Degeneration\|Diabetic Macular Edema	November 2011	Not Applicable
NCT00503906	University of Miami	Breast Cancer	June 2007	Phase 2
NCT05110118	Shandong Boan Biotechnology Co., Ltd	Metastatic Colorectal Cancer\|Non Small Cell Lung Cancer Metastatic\|Non Small Cell Lung Cancer Recurrent	August 4, 2020	Phase 1
NCT03836157	University of Oklahoma\|ImmunoGen, Inc.	Endometrial Cancer\|Endometrial Adenocarcinoma\|Endometrial Serous Adenocarcinoma\|Endometrial Clear Cell Adenocarcinoma	May 31, 2019	Phase 2
NCT04988607	Guangdong Association of Clinical Trials	Lung Cancer	August 2021	Phase 2
NCT04781270	Fudan University	Colorectal Carcinoma\|Liver Metastases	April 15, 2021	Phase 3
NCT05253651	Seagen Inc.\|Merck Sharp & Dohme LLC	Colorectal Neoplasms	November 30, 2022	Phase 3
NCT00085111	National Cancer Institute (NCI)	Unspecified Childhood Solid Tumor, Protocol Specific	December 2003	Phase 1
NCT03367871	University of Miami\|Merck Sharp & Dohme LLC	Cervical Cancer	September 6, 2018	Phase 2
NCT02842294	Centre Hospitalier Universitaire de Besancon	Metastatic Colorectal Cancer\|Quality of Life	May 2013
NCT02248571	iOMEDICO AG\|Arbeitsgemeinschaft fur Internistische Onkologie\|Novartis Pharmaceuticals	Breast Cancer Recurrent\|HER2+Neu-negative Carcinoma of Breast\|Hormone Receptor Positive Malignant Neoplasm of Breast	August 2014	Phase 4
NCT05489211	AstraZeneca\|Daiichi Sankyo, Inc.	Endometrial Cancer\|Gastric Cancer\|Metastatic Castration-resistant Prostate Cancer\|Ovarian Cancer\|Colorectal Cancer	September 6, 2022	Phase 2
NCT03778957	AstraZeneca	Hepatocellular Carcinoma	November 30, 2018	Phase 3
NCT00778102	Hoffmann-La Roche	Colorectal Cancer	October 2008	Phase 2
NCT00253526	National Cancer Institute (NCI)	Adenocarcinoma of the Pancreas\|Recurrent Pancreatic Cancer\|Stage I Pancreatic Cancer\|Stage II Pancreatic Cancer\|Stage III Pancreatic Cancer		Phase 2
NCT01330524	Shahid Beheshti University of Medical Sciences	Acute Nonarteritic Anterior Ischemic Optic Neuropathy	January 2010	Phase 1\|Phase 2
NCT01554059	Sixth Affiliated Hospital, Sun Yat-sen University	Rectal Adenocarcinoma	March 2012	Phase 2
NCT05503667	Shanghai Pulmonary Hospital, Shanghai, China	Lung Adenocarcinoma Stage III\|Lung Adenocarcinoma Stage IV\|EGFR Gene Mutation	February 1, 2022	Phase 2
NCT00321646	Mary-Ellen Taplin, MD\|Beth Israel Deaconess Medical Center\|Duke University\|Genentech, Inc.\|Sanofi\|Dana-Farber Cancer Institute	Prostate Cancer\|Adenocarcinoma of the Prostate	June 2006	Phase 2
NCT00079040	National Cancer Institute (NCI)	Extensive Stage Small Cell Lung Cancer	January 2006	Phase 2
NCT00118235	National Cancer Institute (NCI)	Extensive Stage Small Cell Lung Cancer	December 2004	Phase 2
NCT03275506	ARCAGY+ GINECO GROUP	Ovarian Cancer Stage IV	February 26, 2018	Phase 2
NCT04091217	Hoffmann-La Roche	Melanoma	November 25, 2019	Phase 2
NCT02469987	Mylan Inc.\|Mylan GmbH\|Viatris Inc.	Healthy	April 2015	Phase 1
NCT03117972	Centre Hospitalier Universitaire de Besancon	Metastatic Colorectal Cancer	August 4, 2017	Phase 2
NCT02563002	Merck Sharp & Dohme LLC	Colorectal Carcinoma	November 30, 2015	Phase 3
NCT02591667	Medical University of Vienna	Colorectal Cancer\|Peritoneal Metastasis	March 2016	Phase 2
NCT01760746	University of British Columbia	Proliferative Diabetic Retinopathy (PDR)	July 2012
NCT04148898	Second Affiliated Hospital of Nanchang University\|Nanchang University	Leptomeningeal Metastasis\|Non-small Cell Lung Cancer\|EGFR Activating Mutation	November 1, 2019	Phase 2
NCT02386826	SCRI Development Innovations, LLC\|Novartis	Glioblastoma Multiforme\|Gliosarcoma\|Colorectal Cancer\|Renal Cell Carcinoma	September 22, 2015	Phase 1
NCT01121939	SCRI Development Innovations, LLC\|Genentech, Inc.	Neuroendocrine Carcinoma	May 2010	Phase 2
NCT00006786	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Colorectal Cancer	November 2000	Phase 2
NCT05502991	Henan Provincial People´s Hospital	Glioblastoma	December 11, 2022	Phase 2
NCT00260364	Royal Marsden NHS Foundation Trust\|Professor Cunningham´s Clinical Research Fund\|Hoffmann-La Roche	Pancreatic Cancer	November 2005	Phase 1\|Phase 2
NCT03462212	Fondazione Policlinico Universitario Agostino Gemelli IRCCS\|Istituto Di Ricerche Farmacologiche Mario Negri\|Foundation Medicine	Advanced (Stage IIIB-C-IV) Ovarian, Primary Peritoneal and Fallopian Tube Cancer	March 17, 2021	Phase 1\|Phase 2
NCT03586869	ImmunityBio, Inc.	Pancreatic Cancer	July 28, 2018	Phase 1\|Phase 2
NCT00790010	Dana-Farber Cancer Institute\|Genentech, Inc.\|Bristol-Myers Squibb	Melanoma	February 26, 2009	Phase 1
NCT04679064	Fondazione Policlinico Universitario Agostino Gemelli IRCCS\|GlaxoSmithKline	Ovarian Cancer	December 1, 2020	Phase 3
NCT01705392	Haukeland University Hospital\|The Norwegian Melanoma Group\|Norwegian Cancer Society	Metastatic Malignant Melanoma\|Unresectable Malignant Melanoma	January 2013	Phase 2
NCT03882424	Zhejiang Teruisi Pharmaceutical Inc.	Healthy	June 12, 2018	Phase 1
NCT00737243	SCRI Development Innovations, LLC\|Genentech, Inc.	Carcinoma	August 2008	Phase 2
NCT00496405	Asociación para Evitar la Ceguera en México	Diabetic Macular Edema\|Diabetic Retinopathy	April 2007	Phase 4
NCT01610557	National Eye Institute (NEI)\|The Emmes Company, LLC\|National Institutes of Health Clinical Center (CC)	Diabetic Macular Edema	May 2012	Phase 2
NCT05290948	Shahid Beheshti University of Medical Sciences	Macular Edema	March 12, 2022	Phase 2
NCT00923130	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Renal Cell Carcinoma	January 7, 2009	Phase 2
NCT02842580	Federation Francophone de Cancerologie Digestive	Colorectal Neoplasms	September 2016	Phase 2
NCT00719797	Gruppo Oncologico del Nord-Ovest	Colorectal Cancer	July 2008	Phase 3
NCT03576651	JHL Biotech, Inc.	Healthy Male Subjects	March 24, 2018	Phase 1
NCT02157103	Emory University	Glioblastoma	January 2014	Phase 2
NCT01921790	Sun Yat-sen University\|Hoffmann-La Roche\|Eli Lilly and Company	Extranodal NK+T-cell Lymphoma, Nasal Type	August 2013	Phase 2
NCT04345146	Sun Yat-sen University	Non-squamous Non-small Cell Lung Cancer	January 1, 2020	Phase 2
NCT01186406	Duke University\|Genentech, Inc.\|Eisai Inc.	Glioblastoma Multiforme\|Gliosarcoma	April 2011	Phase 2
NCT00385021	Southwestern Regional Medical Center	Colorectal Neoplasms	October 2006	Phase 2
NCT04512430	Fundación GECP	Non Small Cell Lung Cancer\|EGFR Gene Mutation	December 2, 2020	Phase 2
NCT05116189	Merck Sharp & Dohme LLC	Ovarian Cancer\|Carcinoma, Ovarian Epithelial\|Fallopian Tube Neoplasms	December 13, 2021	Phase 3
NCT02010606	Cedars-Sinai Medical Center	Glioblastoma\|Glioblastoma Multiforme\|Glioma\|Astrocytoma\|Brain Tumor	January 8, 2014	Phase 1
NCT03552770	University Hospital of Ferrara\|Regione Emilia-Romagna	Age-Related Macular Degeneration	November 23, 2014	Phase 4
NCT00673296	National Taiwan University Hospital	Diabetic Retinopathy With Premacular Hemorrhage	January 2007	Not Applicable
NCT00984438	University of Cincinnati\|Eisai Inc.	Glioblastoma Multiforme	June 2009	Phase 1\|Phase 2
NCT00728845	University of Medicine and Dentistry of New Jersey\|National Cancer Institute (NCI)\|Rutgers, The State University of New Jersey	Lung Cancer	June 16, 2008	Phase 1\|Phase 2
NCT00508625	Amgen\|Genentech, Inc.	Non-Small Cell Lung Cancer	June 2006	Phase 2
NCT04592029	Second Affiliated Hospital of Guangzhou Medical University	Hepatocellular Carcinoma Non-resectable	September 27, 2020	Phase 1
NCT01884740	Weill Medical College of Cornell University	Glioblastoma Multiforme\|Fibrillary Astrocytoma of Brain\|Glioma of Brainstem\|Anaplastic Astrocytoma\|Pilomyxoid Astrocytoma\|Mixed Oligodendroglioma-Astrocytoma\|Brain Stem Glioma\|Diffuse Intrinsic Pontine Glioma	June 2013	Phase 1\|Phase 2
NCT03596281	Gustave Roussy, Cancer Campus, Grand Paris	Ovarian Cancer	December 5, 2018	Phase 1
NCT01249638	Ludwig-Maximilians - University of Munich\|Roche Pharma AG	Colorectal Cancer Metastatic	December 2010	Phase 3
NCT00390026	St. Erik Eye Hospital	Age-Related Macular Degeneration	November 2006	Phase 3
NCT00906516	Bradmer Pharmaceuticals Inc.	Brain Tumors	May 2009	Phase 2
NCT00293332	University of California, San Francisco\|National Cancer Institute (NCI)	Lung Cancer	December 2005	Phase 2
NCT05158062	Kosei Hasegawa, MD, PhD\|Saitama Medical University International Medical Center	Carcinoma, Ovarian Epithelial	April 20, 2022	Phase 2
NCT00754351	University Hospital of Crete	Breast Cancer	September 2008	Phase 2
NCT04634604	Jaeb Center for Health Research\|Pediatric Eye Disease Investigator Group\|National Eye Institute (NEI)	Retinopathy of Prematurity	April 27, 2022	Phase 3
NCT00655850	University of Alabama at Birmingham\|Genentech, Inc.	Non-Small Cell Lung Cancer	March 2008	Phase 2
NCT00426829	M.D. Anderson Cancer Center\|Genentech, Inc.	Liver Cancer\|Hepatocellular Carcinoma\|Cholangiocarcinoma	May 2007	Phase 1
NCT01508000	European Organisation for Research and Treatment of Cancer - EORTC\|Amgen\|Roche Pharma AG	Colorectal Cancer Metastatic\|Liver Metastases\|KRAS Wild Type Colorectal Cancer	June 2013	Phase 2
NCT00585377	University of Utah\|Genentech, Inc.	Cancer	August 2007	Phase 2
NCT03828227	GERCOR - Multidisciplinary Oncology Cooperative Group	Elderly Patients\|Metastatic Colorectal Cancer\|Quality of Life	June 7, 2019	Phase 3
NCT00513786	David O´Malley\|Genentech, Inc.\|Ohio State University Comprehensive Cancer Center	Endometrial Cancer	August 1, 2007	Phase 2
NCT05110209	Novartis Pharmaceuticals\|Novartis	Age-related Macular Degeneration (AMD)	July 15, 2020
NCT01478594	AVEO Pharmaceuticals, Inc.	Colorectal Cancer	December 2011	Phase 2
NCT01223235	Memorial Sloan Kettering Cancer Center\|Genentech, Inc.	Fallopian Tubes Cancer\|Ovarian Cancer\|Peritoneal Cancer	October 2010	Not Applicable
NCT01932125	Hoffmann-La Roche	Ovarian Neoplasms\|Peritoneal Neoplasms\|Fallopian Tube Neoplasms	December 5, 2018	Phase 4
NCT00543504	M.D. Anderson Cancer Center	Advanced Cancer	October 10, 2007	Phase 1
NCT00333775	Hoffmann-La Roche	Breast Cancer	March 2006	Phase 3
NCT05398861	Henan Cancer Hospital\|Qilu Pharmaceutical Co., Ltd.\|Beijing Biostar Technologies, Ltd	HER-2 Negative Breast Cancer	June 1, 2022	Phase 2
NCT01356290	Medical University of Vienna	Medulloblastoma Recurrent\|Ependymoma Recurrent\|ATRT Recurrent	April 2014	Phase 2
NCT05364489	The First Affiliated Hospital of Zhengzhou University	Advanced Colorectal Cancer	June 15, 2022	Phase 2
NCT00192075	Eli Lilly and Company	Colorectal Cancer	June 2003	Phase 2
NCT02348008	Arkadiusz Z. Dudek, MD\|Merck Sharp & Dohme LLC\|Big Ten Cancer Research Consortium	Clear Cell Renal Carcinoma	March 2015	Phase 1\|Phase 2
NCT05170594	The Second Affiliated Hospital of Shandong First Medical University	Ovarian Cancer	December 24, 2021	Phase 2
NCT02446431	Miller Children´s & Women´s Hospital Long Beach\|Children´s Hospital of Orange County	Solid Tumor	July 2014	Early Phase 1
NCT00531076	Amsterdam UMC, location VUmc	Toxicity	October 2007	Phase 1
NCT01744756	Instituto de Olhos de Goiania	Recurrent Pterygium	February 2012	Phase 2\|Phase 3
NCT04213222	Peking University People´s Hospital	Colon Cancer\|Rectal Cancer\|Liver Metastases	October 2020
NCT00520975	National Cancer Institute (NCI)	Breast Carcinoma\|Recurrent Breast Carcinoma\|Stage IV Breast Cancer	November 2007	Phase 3
NCT05097911	National University Hospital, Singapore	Advanced Hepatocellular Carcinoma	August 2, 2021	Phase 1
NCT02695641	Mayo Clinic	End Stage Renal Disease\|Hemodialysis Vascular Access Failure	August 1, 2019	Early Phase 1
NCT02462304	The University of Hong Kong\|Nagoya City University\|Asahikawa Medical College\|University of Fukui\|Eguchi Eye Clinic\|Kyoto University\|Nagasaki University\|Osaka Medical College\|Kyushu University\|Tokyo Medical University Hachioji Medical Centre\|Hokkaido University\|Kyorin University\|Inje University\|Pusan National University\|Kyungpook National University Hospital\|Chungnam National University Hospital\|Sun Cheon Hyang University\|Kyunghee University\|Yeungnam University Hospital\|Korea University\|National University Hospital, Singapore\|Yamagata University	Diabetic Macula Edema	June 2015	Phase 4
NCT01492673	Memorial Sloan Kettering Cancer Center\|Genentech, Inc.\|Children´s Mercy Hospital Kansas City\|Penn State University\|University of Colorado, Denver\|Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|Phoenix Children´s Hospital Center for Cancer & Blood Disorders\|Alberta Children´s Hospital\|MD Anderson Cancer Center Orlando\|M.D. Anderson Cancer Center	Neuroblastoma\|Sarcoma	December 2011	Phase 2
NCT05185505	The Methodist Hospital Research Institute\|Genentech, Inc.	Hepatocellular Carcinoma\|Hepatocellular Cancer	March 17, 2022	Phase 4
NCT03149003	Sumitomo Pharma Oncology, Inc.	Glioblastoma	December 8, 2017	Phase 3
NCT00112918	Hoffmann-La Roche\|National Cancer Institute (NCI)	Colorectal Cancer	December 2004	Phase 3
NCT00393068	SCRI Development Innovations, LLC\|Genentech, Inc.	Esophageal Cancer	February 2007	Phase 2
NCT02776683	Boehringer Ingelheim	Colorectal Neoplasms	June 8, 2016	Phase 3
NCT00557492	Amer Zureikat\|University of Pittsburgh	Pancreatic Cancer	December 2006	Phase 2
NCT01959490	Case Comprehensive Cancer Center\|National Cancer Institute (NCI)	Stage II Breast Cancer\|Stage IIIA Breast Cancer\|Stage IIIB Breast Cancer\|Stage IIIC Breast Cancer	September 24, 2013	Phase 2
NCT00988897	Sanofi	Colorectal Neoplasms	October 2009	Phase 2
NCT00410774	University of California, San Francisco\|National Cancer Institute (NCI)	Pancreatic Cancer	July 2006	Phase 1\|Phase 2
NCT04753216	Northwestern University\|Ipsen Biopharmaceuticals\|National Cancer Institute (NCI)	Platinum-Resistant Fallopian Tube Carcinoma\|Platinum-Resistant Ovarian Carcinoma\|Platinum-Resistant Primary Peritoneal Carcinoma\|Recurrent Fallopian Tube Carcinoma\|Recurrent Ovarian Carcinoma\|Recurrent Primary Peritoneal Carcinoma\|Refractory Fallopian Tube Carcinoma\|Refractory Ovarian Carcinoma\|Refractory Primary Peritoneal Carcinoma	March 16, 2021	Phase 2
NCT00139360	Haukeland University Hospital\|Norwegian Cancer Society\|Hoffmann-La Roche	Metastatic Melanoma	May 2005	Phase 2
NCT04094688	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Colorectal Adenocarcinoma	September 30, 2019	Phase 3
NCT00622726	The University of Texas Health Science Center, Houston	Retinopathy of Prematurity	March 2008	Phase 2
NCT00632541	Hoosier Cancer Research Network\|Genentech, Inc.\|Bayer\|Amgen	Metastatic Breast Cancer	October 2007	Phase 2
NCT02005120	Zhejiang University	Non Small Cell Lung Cancer	December 2013	Phase 2
NCT00448136	Hoffmann-La Roche	Neoplasms	July 2007	Phase 2
NCT05029973	Tianjin Medical University Cancer Institute and Hospital	Hepatocellular Carcinoma	May 10, 2021	Phase 2
NCT02200354	Kobe City General Hospital	Advanced Non-small Cell Lung Cancer	July 2014	Phase 2
NCT05444088	Suzhou Suncadia Biopharmaceuticals Co., Ltd.	Advanced Hepatocellular Carcinoma	August 1, 2022	Phase 1\|Phase 2
NCT00095225	Genentech, Inc.	Non-Small-Cell Lung Carcinoma\|Neoplasm Recurrence, Local	July 2004	Phase 2
NCT04563338	University Health Network, Toronto\|Hoffmann-La Roche	Hepatocellular Carcinoma\|Non-small Cell Lung Cancer Metastatic\|Liver Metastases	June 4, 2021	Phase 2
NCT00391092	Hoffmann-La Roche	Breast Cancer	September 2006	Phase 3
NCT03676192	Celltrion	Adenocarcinoma of Lung	December 19, 2018	Phase 3
NCT00609622	Pfizer	Colorectal Neoplasms	April 2008	Phase 2
NCT01130519	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	HLRCC\|Sporadic Papillary Renal Cell Cancer	May 6, 2010	Phase 2
NCT01308684	Hoffmann-La Roche	Glioblastoma Multiforme	May 2011	Phase 1
NCT00418938	Amgen	Cancer\|Colon Cancer\|Colorectal Cancer\|Metastatic Cancer\|Rectal Cancer\|Metastatic Colorectal Cancer	November 1, 2006	Phase 2
NCT04575415	Guangdong Association of Clinical Trials	NSCLC	October 7, 2020
NCT03148132	Universidad Autonoma de San Luis Potosí\|Hospital Central Dr. Ignacio Morones Prieto	Retinopathy of Prematurity Both Eyes\|Retinal Disease\|Premature Birth\|Eye Diseases	May 23, 2017	Phase 4
NCT00707889	AbbVie (prior sponsor, Abbott)\|Genentech, Inc.\|AbbVie	Advanced Colorectal Cancer\|Adenocarcinoma of the Colon\|Adenocarcinoma of the Rectum	October 2008	Phase 2
NCT00946712	Southwest Oncology Group\|National Cancer Institute (NCI)	Recurrent Large Cell Lung Carcinoma\|Recurrent Lung Adenocarcinoma\|Recurrent Squamous Cell Lung Carcinoma\|Stage IV Large Cell Lung Carcinoma\|Stage IV Lung Adenocarcinoma\|Stage IV Squamous Cell Lung Carcinoma	July 15, 2009	Phase 3
NCT00400803	Masonic Cancer Center, University of Minnesota\|Eli Lilly and Company\|Genentech, Inc.	Carcinoma, Non-Small-Cell Lung	March 2007	Phase 2
NCT01069328	Bayer	Carcinoma, Non-Small-Cell Lung\|Lung Cancer	July 2006	Phase 1
NCT03829410	Cardiff Oncology	Metastatic Colorectal Cancer\|KRAS Gene Mutation	May 6, 2019	Phase 1\|Phase 2
NCT00442637	Dutch Colorectal Cancer Group\|Koningin Wilhelmina Fonds\|Sanofi\|Hoffmann-La Roche	Colorectal Cancer Metastatic	January 2007	Phase 3
NCT01516216	Dana-Farber Cancer Institute	Metastatic Colorectal Cancer	April 13, 2012	Phase 2
NCT00438204	Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Lung Cancer	May 2006	Phase 2
NCT00060411	National Cancer Institute (NCI)	Mucinous Adenocarcinoma of the Colon\|Mucinous Adenocarcinoma of the Rectum\|Recurrent Colon Cancer\|Recurrent Rectal Cancer\|Signet Ring Adenocarcinoma of the Colon\|Signet Ring Adenocarcinoma of the Rectum\|Stage IIIA Colon Cancer\|Stage IIIA Rectal Cancer\|Stage IIIB Colon Cancer\|Stage IIIB Rectal Cancer\|Stage IIIC Colon Cancer\|Stage IIIC Rectal Cancer\|Stage IVA Colon Cancer\|Stage IVA Rectal Cancer\|Stage IVB Colon Cancer\|Stage IVB Rectal Cancer	June 2003	Phase 1
NCT00314353	NSABP Foundation Inc\|Genentech, Inc.\|Hoffmann-La Roche\|International Drug Development Institute	Colorectal Neoplasms	March 2006	Phase 2
NCT00523640	University of Chicago\|Genentech, Inc.\|Eli Lilly and Company	Carcinoma, Renal Cell	March 2005	Phase 2
NCT02047214	Cortice Biosciences, Inc.	Glioblastoma Multiforme	January 2014	Phase 2
NCT00005061	European Organisation for Research and Treatment of Cancer - EORTC	Unspecified Adult Solid Tumor, Protocol Specific	December 1999	Phase 1
NCT00951496	National Cancer Institute (NCI)\|NRG Oncology	Fallopian Tube Clear Cell Adenocarcinoma\|Fallopian Tube Endometrioid Adenocarcinoma\|Fallopian Tube Mucinous Adenocarcinoma\|Fallopian Tube Serous Adenocarcinoma\|Fallopian Tube Transitional Cell Carcinoma\|Fallopian Tube Undifferentiated Carcinoma\|Malignant Ovarian Brenner Tumor\|Ovarian Clear Cell Adenocarcinoma\|Ovarian Endometrioid Adenocarcinoma\|Ovarian Mucinous Adenocarcinoma\|Ovarian Seromucinous Carcinoma\|Ovarian Serous Adenocarcinoma\|Ovarian Transitional Cell Carcinoma\|Ovarian Undifferentiated Carcinoma\|Primary Peritoneal Clear Cell Adenocarcinoma\|Primary Peritoneal Endometrioid Adenocarcinoma\|Primary Peritoneal Serous Adenocarcinoma\|Primary Peritoneal Transitional Cell Carcinoma\|Primary Peritoneal Undifferentiated Carcinoma\|Stage II Fallopian Tube Cancer AJCC v6 and v7\|Stage II Ovarian Cancer AJCC v6 and v7\|Stage IIA Fallopian Tube Cancer AJCC v6 and v7\|Stage IIA Ovarian Cancer AJCC V6 and v7\|Stage IIB Fallopian Tube Cancer AJCC v6 and v7\|Stage IIB Ovarian Cancer AJCC v6 and v7\|Stage IIC Fallopian Tube Cancer AJCC v6 and v7\|Stage IIC Ovarian Cancer AJCC v6 and v7\|Stage III Ovarian Cancer AJCC v6 and v7\|Stage III Primary Peritoneal Cancer AJCC v7\|Stage IIIA Ovarian Cancer AJCC v6 and v7\|Stage IIIA Primary Peritoneal Cancer AJCC v7\|Stage IIIB Ovarian Cancer AJCC v6 and v7\|Stage IIIB Primary Peritoneal Cancer AJCC v7\|Stage IIIC Ovarian Cancer AJCC v6 and v7\|Stage IIIC Primary Peritoneal Cancer AJCC v7\|Stage IV Fallopian Tube Cancer AJCC v6 and v7\|Stage IV Ovarian Cancer AJCC v6 and v7\|Stage IV Primary Peritoneal Cancer AJCC v7	August 11, 2009	Phase 3
NCT00970684	Nathan Pennell, MD, PhD\|National Cancer Institute (NCI)\|Case Comprehensive Cancer Center	Lung Cancer	September 2009	Phase 2
NCT01837862	Julie Krystal\|Janssen Pharmaceuticals\|Northwell Health	Pilomyxoid Astrocytoma\|Pilocytic Astrocytoma\|Glioma, Astrocytic\|Optic Nerve Glioma\|Pleomorphic Xanthoastrocytoma\|Glioblastoma Multiforme\|Anaplastic Astrocytoma\|Gliosarcoma\|Diffuse Intrinsic Pontine Glioma\|DIPG\|Low-grade Glioma\|Brainstem Glioma	October 22, 2013	Phase 1\|Phase 2
NCT00642759	Massachusetts General Hospital\|Dana-Farber Cancer Institute\|Celgene Corporation\|Genentech, Inc.	Non-small Cell Lung Cancer	April 2008	Phase 2
NCT04681677	Xoft, Inc.\|Icad, Inc.	Glioblastoma\|Recurrent Glioblastoma\|GBM\|Recurrent GBM	November 2, 2021	Phase 2
NCT01077713	Hoffmann-La Roche	Non-Squamous Non-Small Cell Lung Cancer	February 2010	Phase 2
NCT01271166	Novartis Pharmaceuticals\|Novartis	Advanced Colorectal Cancer	October 2007	Phase 1
NCT00859222	Patrick Y. Wen, MD\|Brigham and Women´s Hospital\|Massachusetts General Hospital\|Beth Israel Deaconess Medical Center\|Northwestern University\|University of Virginia\|Genentech, Inc.\|Novartis\|Dana-Farber Cancer Institute	Malignant Glioma	March 2009	Phase 1\|Phase 2
NCT05518994	Henan Provincial People´s Hospital	Astrocytoma of Brain	December 1, 2022	Phase 2
NCT03380689	Fujian Cancer Hospital	Metastatic Colorectal Cancer	January 5, 2018	Phase 1
NCT00469443	Hellenic Oncology Research Group\|University Hospital of Crete	Colorectal Cancer	December 2006	Phase 3
NCT01122966	Samsung Medical Center	Glaucoma	March 2010	Phase 2\|Phase 3
NCT00654836	Loyola University\|Genentech, Inc.\|Celgene Corporation	Breast Cancer	October 2007	Phase 2
NCT00748657	National Cancer Institute (NCI)\|NRG Oncology	Malignant Ovarian Epithelial Tumor\|Ovarian Granulosa Cell Tumor\|Ovarian Gynandroblastoma\|Ovarian Sertoli-Leydig Cell Tumor\|Ovarian Sex Cord Tumor With Annular Tubules\|Ovarian Sex Cord-Stromal Tumor\|Ovarian Sex Cord-Stromal Tumor of Mixed or Unclassified Cell Types\|Ovarian Steroid Cell Tumor	September 22, 2008	Phase 2
NCT02142803	National Cancer Institute (NCI)	Adult Glioblastoma\|Endometrial Clear Cell Adenocarcinoma\|Endometrial Serous Adenocarcinoma\|Ovarian Clear Cell Cystadenocarcinoma\|Ovarian Endometrioid Adenocarcinoma\|Ovarian Mucinous Cystadenocarcinoma\|Ovarian Serous Cystadenocarcinoma\|Recurrent Fallopian Tube Carcinoma\|Recurrent Ovarian Carcinoma\|Recurrent Primary Peritoneal Carcinoma\|Recurrent Uterine Corpus Cancer\|Solid Neoplasm\|Stage IIIA Fallopian Tube Cancer AJCC v7\|Stage IIIA Ovarian Cancer AJCC v6 and v7\|Stage IIIA Primary Peritoneal Cancer AJCC v7\|Stage IIIB Fallopian Tube Cancer AJCC v7\|Stage IIIB Ovarian Cancer AJCC v6 and v7\|Stage IIIB Primary Peritoneal Cancer AJCC v7\|Stage IIIC Fallopian Tube Cancer AJCC v7\|Stage IIIC Ovarian Cancer AJCC v6 and v7\|Stage IIIC Primary Peritoneal Cancer AJCC v7\|Stage IV Fallopian Tube Cancer AJCC v6 and v7\|Stage IV Ovarian Cancer AJCC v6 and v7\|Stage IV Primary Peritoneal Cancer AJCC v7	May 20, 2014	Phase 1
NCT01853813	Gruppo Italiano per lo studio dei Carcinomi dell´Apparato Digerente\|Azienda Ospedaliero, Universitaria Ospedali Riuniti	Colorectal Cancer Stage II	May 2013	Phase 2
NCT01254526	Genentech, Inc.	Breast Cancer	December 2010	Phase 1
NCT00313768	Pfizer	Carcinoma, Non-Small-Cell Lung	December 2005	Phase 2
NCT05588297	Shanghai Changzheng Hospital	Colorectal Cancer Liver Metastases	October 2022	Phase 2
NCT00150657	St. John Providence Health System\|Genentech, Inc.\|Eli Lilly and Company	Non-Small Cell Lung Cancer	November 2004	Phase 2
NCT03813394	National University Hospital, Singapore\|Merck Sharp & Dohme LLC	Locally Recurrent Cancer\|Metastatic Nasopharyngeal Cancer	May 1, 2019	Phase 1\|Phase 2
NCT03178552	Hoffmann-La Roche	Non-Small Cell Lung Cancer	September 22, 2017	Phase 2\|Phase 3
NCT01640444	Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)\|Roche Pharma AG	Colorectal Cancer Metastatic	July 2012	Phase 2
NCT00369889	Indiana University School of Medicine\|Genentech, Inc.\|Indiana University	Thymic Cancer\|Thymoma	August 2006	Phase 2
NCT00464347	National Eye Institute (NEI)\|QLT Inc.	Age-Related Macular Degeneration	January 2007	Phase 2
NCT00723125	William Sikov MD\|Yale University\|Brown University	Breast Cancer	September 2008	Phase 2
NCT01137604	Eisai Inc.	Glioma	November 9, 2010	Phase 2
NCT04919629	Roswell Park Cancer Institute	Fallopian Tube Carcinosarcoma\|Fallopian Tube Adenocarcinoma\|Fallopian Tube Serous Adenocarcinoma\|Ovarian Carcinosarcoma\|Ovarian Clear Cell Adenocarcinoma\|Ovarian Endometrioid Adenocarcinoma\|Ovarian Serous Adenocarcinoma\|Primary Peritoneal Adenocarcinoma\|Recurrent Fallopian Tube Carcinoma\|Recurrent Ovarian Carcinoma\|Recurrent Primary Peritoneal Carcinoma	December 15, 2022	Phase 2
NCT03193190	Hoffmann-La Roche	Pancreatic Adenocarcinoma	July 5, 2017	Phase 1\|Phase 2
NCT04099836	Duke University	Non Small Cell Lung Cancer	July 9, 2020	Phase 2
NCT02348918	Allegro Ophthalmics, LLC\|Trial Runners, LLC\|Duke University	Diabetic Macular Edema	October 13, 2014	Phase 2
NCT04981509	National Cancer Institute (NCI)	Advanced Papillary Renal Cell Carcinoma\|Advanced Renal Cell Carcinoma\|Hereditary Leiomyomatosis and Renal Cell Carcinoma\|Recurrent Renal Cell Carcinoma\|Sporadic Papillary Renal Cell Carcinoma\|Stage III Renal Cell Cancer AJCC v8\|Stage IV Renal Cell Cancer AJCC v8	September 17, 2021	Phase 2
NCT00628810	Federation Francophone de Cancerologie Digestive	Colorectal Cancer	January 2007	Phase 2
NCT00405405	Sidney Kimmel Cancer Center at Thomas Jefferson University\|Genentech, Inc.\|Thomas Jefferson University	Head and Neck Cancer\|Parotid Gland Cancer\|Thyroid Gland Cancer\|Melanoma\|Stage IV Head and Neck Cancer	December 2006	Phase 1
NCT00508872	M.D. Anderson Cancer Center\|Sanofi	Colorectal Liver Metastases	November 2005	Phase 2
NCT00271609	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Recurrent High-Grade Gliomas\|Malignant Gliomas	December 2005	Phase 2
NCT00684996	National Cancer Institute (NCI)	Recurrent Renal Cell Cancer\|Renal Cell Carcinoma\|Stage III Renal Cell Cancer\|Stage IV Renal Cell Cancer	June 2008	Phase 1\|Phase 2
NCT00813059	Mount Sinai Hospital, Canada	Non-arteritic Anterior Ischemic Optic Neuropathy	February 2009	Phase 2
NCT00779311	Accelerated Community Oncology Research Network\|Bayer	Metastatic Colorectal Cancer	October 2008	Phase 1
NCT00423930	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)\|Genentech, Inc.	Head and Neck Cancer	October 2006	Phase 2
NCT02308527	University of Birmingham\|Cancer Research UK\|Roche Pharma AG\|Imagine for Margo\|EUSA Pharma, Inc.	Neuroblastoma	July 2013	Phase 2
NCT04958811	Georgetown University\|Genentech, Inc.	Non-squamous Non-small-cell Lung Cancer	December 21, 2021	Phase 2
NCT03779191	Instituto Nacional de Cancerologia de Mexico\|Roche Pharma AG	ALK Gene Rearrangement Positive\|Non-Squamous Non-Small Cell Neoplasm of Lung	April 8, 2020	Phase 2
NCT00614822	Christiana Care Health Services\|Eli Lilly and Company	Non Small Cell Lung Cancer	November 2007	Phase 2
NCT00975897	Medical Research Council\|National Cancer Institute (NCI)	Colorectal Cancer	July 2009	Phase 2\|Phase 3
NCT03133546	ETOP IBCSG Partners Foundation\|AstraZeneca\|Hoffmann-La Roche	Non Small Cell Lung Cancer Metastatic	May 31, 2017	Phase 2
NCT00530868	University of Alabama at Birmingham\|Genentech, Inc.\|Breast Cancer Research Foundation	Breast Cancer\|Cancer of the Breast\|Breast Neoplasm	October 8, 2007	Phase 2
NCT01077739	Hoffmann-La Roche	Colorectal Cancer	July 2009	Phase 2
NCT01495988	Melanoma Research Foundation Breakthrough Consortium\|Genentech, Inc.	Melanoma\|Metastatic Melanoma	August 2013	Phase 2
NCT00406172	Asociación para Evitar la Ceguera en México	Cystoid Macular Edema		Phase 3
NCT01311960	Chulalongkorn University	Pterygium\|Bevacizumab\|VEGF\|Anti-VEGF	December 2010	Phase 3
NCT00722865	Massachusetts General Hospital\|Genentech, Inc.	Hodgkin Lymphoma	September 2008	Phase 2
NCT03740165	Merck Sharp & Dohme LLC\|European Network of Gynaecological Oncological Trial Groups (ENGOT)\|Gynecologic Oncology Group	Ovarian Cancer\|Fallopian Tube Cancer\|Peritoneal Neoplasms	December 18, 2018	Phase 3
NCT01588704	Si-Yu Wang\|Sun Yat-sen University	Lung Cancer	April 2012	Phase 2
NCT01181609	Hoffmann-La Roche	Colorectal Cancer	June 2005	Phase 2
NCT00469976	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Lung Cancer	June 2007	Phase 2
NCT00596297	University of Sao Paulo	Diabetic Retinopathy\|Vitreous Hemorrhage	November 2007	Phase 1\|Phase 2
NCT00448019	M.D. Anderson Cancer Center\|Genentech, Inc.	Chronic Lymphocytic Leukemia	February 2007	Phase 2
NCT00047762	Genentech, Inc.	Colorectal Cancer	October 2002	Phase 1
NCT00583622	M.D. Anderson Cancer Center	Ovarian Cancer	December 2007	Phase 2
NCT02511405	Vascular Biogenics Ltd. operating as VBL Therapeutics	Glioblastoma	August 2015	Phase 3
NCT00642824	Hoffmann-La Roche	Non-Squamous Non-Small Cell Lung Cancer	May 2007	Phase 2
NCT04829383	Howard S Hochster\|Genentech, Inc.\|Rutgers Cancer Institute of New Jersey\|Big Ten Cancer Research Consortium	Unresectable Hepatocellular Carcinoma	March 22, 2021	Phase 2
NCT00976573	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Melanoma (Skin)	April 2010	Phase 2
NCT00356031	Massachusetts General Hospital\|National Institutes of Health (NIH)\|National Cancer Institute (NCI)	Soft Tissue Sarcoma\|Fibrous Histiocytoma\|Liposarcoma\|Leiomyosarcoma\|Fibrosarcoma\|Synovial Sarcoma	July 2006	Phase 2
NCT02020707	Mayo Clinic\|National Cancer Institute (NCI)	Cervical Adenocarcinoma\|Cervical Adenosarcoma\|Cervical Adenosquamous Carcinoma\|Cervical Carcinosarcoma\|Cervical Squamous Cell Carcinoma\|Endometrial Adenosquamous Carcinoma\|Endometrial Clear Cell Adenocarcinoma\|Endometrial Endometrioid Adenocarcinoma\|Endometrial Mixed Cell Adenocarcinoma\|Endometrial Mucinous Adenocarcinoma\|Endometrial Serous Adenocarcinoma\|Endometrial Undifferentiated Carcinoma\|Fallopian Tube Adenocarcinoma\|Fallopian Tube Carcinosarcoma\|Fallopian Tube Clear Cell Adenocarcinoma\|Fallopian Tube Endometrioid Adenocarcinoma\|Fallopian Tube Mucinous Adenocarcinoma\|Fallopian Tube Serous Adenocarcinoma\|Fallopian Tube Squamous Cell Carcinoma\|Fallopian Tube Transitional Cell Carcinoma\|Fallopian Tube Undifferentiated Carcinoma\|Malignant Female Reproductive System Neoplasm\|Malignant Ovarian Clear Cell Tumor\|Malignant Ovarian Endometrioid Tumor\|Malignant Ovarian Epithelial Tumor\|Malignant Ovarian Mucinous Tumor\|Malignant Peritoneal Neoplasm\|Malignant Solid Neoplasm\|Ovarian Carcinosarcoma\|Ovarian Clear Cell Adenocarcinoma\|Ovarian Endometrioid Adenocarcinoma\|Ovarian High Grade Serous Adenocarcinoma\|Ovarian Mucinous Adenocarcinoma\|Ovarian Serous Adenocarcinoma\|Ovarian Transitional Cell Carcinoma\|Ovarian Undifferentiated Carcinoma\|Platinum-Resistant Fallopian Tube Carcinoma\|Platinum-Resistant Ovarian Carcinoma\|Platinum-Resistant Primary Peritoneal Carcinoma\|Platinum-Sensitive Ovarian Carcinoma\|Primary Peritoneal Carcinosarcoma\|Primary Peritoneal Clear Cell Adenocarcinoma\|Primary Peritoneal Serous Adenocarcinoma\|Primary Peritoneal Transitional Cell Carcinoma\|Primary Peritoneal Undifferentiated Carcinoma\|Stage IV Cutaneous Melanoma AJCC v6 and v7\|Unresectable Melanoma\|Uterine Corpus Carcinosarcoma	February 3, 2014	Phase 1
NCT01251926	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Neoplasms	November 15, 2010	Phase 1
NCT03574779	Tesaro, Inc.	Ovarian Neoplasms	November 15, 2018	Phase 1\|Phase 2
NCT03711240	National Cheng-Kung University Hospital	Colorectal Cancer	January 8, 2019	Phase 2
NCT01852409	Peking University	Refractory Malignant Ascites	May 2013	Phase 1
NCT05617430	Wuhan Union Hospital, China	Hepatocellular Carcinoma	November 2, 2022	Phase 2
NCT01749384	National Cancer Institute (NCI)	Solid Neoplasm	December 6, 2012	Phase 1
NCT01814163	Spanish Lung Cancer Group	Nonsquamous Nonsmall Cell Neoplasm of Lung	February 2011
NCT02873195	Academic and Community Cancer Research United\|National Cancer Institute (NCI)	Metastatic Colorectal Carcinoma\|Recurrent Colorectal Carcinoma\|Refractory Colorectal Carcinoma\|Stage IV Colorectal Cancer AJCC v7\|Stage IVA Colorectal Cancer AJCC v7\|Stage IVB Colorectal Cancer AJCC v7	July 7, 2017	Phase 2
NCT00671970	Duke University\|Genentech, Inc.	Glioblastoma\|Gliosarcoma	February 2007	Phase 2
NCT00642603	Hoffmann-La Roche	Colorectal Cancer	May 2008	Phase 2
NCT01017250	Duke University\|Genentech, Inc.	Malignant Glioma	December 2009	Not Applicable
NCT04627363	Sun Yat-sen University\|Second Affiliated Hospital of Guangzhou Medical University	Hepatocellular Carcinoma\|Bevacizumab\|Liver Neoplasms\|Toripalimab\|Oxaliplatin	January 1, 2021	Phase 2
NCT00961415	Hoffmann-La Roche	Non-Squamous Non-Small Cell Lung Cancer	August 2009	Phase 3
NCT00679029	University of Nebraska\|National Cancer Institute (NCI)	HER2-negative Breast Cancer\|Stage II Breast Cancer\|Stage IIIA Breast Cancer\|Stage IIIB Breast Cancer\|Stage IIIC Breast Cancer	May 2008	Phase 2
NCT00462865	Brown University\|Women and Infants Hospital of Rhode Island\|Rhode Island Hospital\|The Miriam Hospital\|Memorial Hospital of Rhode Island\|University of New Mexico Cancer Center	Breast Cancer	November 2007	Phase 2
NCT01022918	Centre Georges Francois Leclerc\|National Cancer Institute, France\|Association de Neuro-Oncologues d´Expression Francaise\|UNICANCER\|Hoffmann-La Roche\|Pfizer	Naive Unresectable Glioblastoma	January 2009	Phase 2
NCT00386828	British Columbia Cancer Agency	Advanced Colorectal Cancer	October 2006	Phase 2
NCT00556348	Instituto de Olhos de Goiania	Age Related Macular Degeneration	November 2005	Phase 4
NCT00708448	University of Utah	Cancer\|Non Small Cell Lung Cancer	March 28, 2008	Phase 1
NCT02663271	University of Florida\|NovoCure Ltd.	Glioblastoma Multiforme\|Glioblastoma\|Malignant Glioma\|GBM	December 19, 2016	Phase 2
NCT02574663	TG Therapeutics, Inc.\|SCRI Development Innovations, LLC	Pancreatic Cancer\|Colorectal Cancer\|Rectal Cancer\|Gastric Cancer\|Esophageal Cancer\|Gastrointestinal Stromal Tumor (GIST)	September 11, 2015	Phase 1
NCT00301990	Jonsson Comprehensive Cancer Center\|National Cancer Institute (NCI)	Kidney Cancer	September 2005	Phase 2
NCT00932438	University of Louisville\|Biocompatibles UK Ltd	Colon Cancer With Metastases to the Liver	June 2009	Phase 1\|Phase 2
NCT00968240	Northwell Health	Glioblastoma Multiforme\|Anaplastic Astrocytoma	July 2009	Phase 1
NCT01740258	Duke University\|Genentech, Inc.	Malignant Glioma\|Grade 4 Malignant Glioma\|Glioblastoma\|Gliosarcoma	January 2013	Phase 2
NCT00290615	Herbert Hurwitz\|National Cancer Institute (NCI)\|Duke University	Colorectal Cancer	January 2006	Phase 2
NCT00873275	City of Hope Medical Center\|National Cancer Institute (NCI)	Colorectal Cancer	March 11, 2009	Phase 1
NCT03929666	Zymeworks Inc.	HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer	August 29, 2019	Phase 2
NCT01408030	James Gossage\|HHT Foundation International\|Augusta University	Telangiectasia, Hereditary Hemorrhagic\|Epistaxis	August 2011	Phase 2
NCT00516295	National Cancer Institute (NCI)	Ewing Sarcoma of Bone\|Extraosseous Ewing Sarcoma\|Peripheral Primitive Neuroectodermal Tumor\|Recurrent Ewing Sarcoma+Peripheral Primitive Neuroectodermal Tumor	February 2008	Phase 2
NCT05217680	Laboratorios Sophia S.A de C.V.	Diabetic Macular Edema	May 17, 2021	Phase 3
NCT03391219	Shahid Beheshti University of Medical Sciences	Retinal Vein Occlusion	January 2018	Phase 2\|Phase 3
NCT00193219	SCRI Development Innovations, LLC\|Bristol-Myers Squibb	Colon Cancer	July 2005	Phase 2
NCT04135898	Shanghai Institute Of Biological Products	Healthy Male	October 30, 2019	Phase 1
NCT04674254	Cairo University	Proliferative Diabetic Retinopathy\|Vascular Endothelial Growth Factor Overexpression\|Diabetic Retinopathy	March 30, 2021	Phase 4
NCT02305615	Hoffmann-La Roche	Colorectal Cancer	January 13, 2015
NCT00776763	Ophthalmological Association Edelweiss\|University of Cologne	Proliferative Diabetic Retinopathy\|Age Related Macular Degeneration	October 2008	Phase 2
NCT02075086	Grupo Hospital de Madrid	Colorectal Cancer	July 2011	Phase 2
NCT04247984	Cancer Institute and Hospital, Chinese Academy of Medical Sciences\|Beijing Hospital\|Henan Cancer Hospital\|Liaoning Tumor Hospital & Institute\|Jiangsu Cancer Institute & Hospital	Metastatic Colorectal Cancer	May 1, 2018	Phase 2
NCT01091896	University of Sao Paulo	Vitreous Hemorrhage Secondary to PDR	January 2010	Phase 2
NCT05325229	CSPC ZhongQi Pharmaceutical Technology Co., Ltd.	Platinum-resistant Recurrent Ovarian Cancer	August 18, 2022	Phase 2
NCT01854593	Nihon University	Proliferative Diabetic Retinopathy\|Diabetic Traction Retinal Detachment\|Vitreous Hemorrhage	May 2012	Phase 4
NCT01090830	Holy Cross Hospital, Florida	Non-Small-Cell Lung Carcinoma	April 2010	Phase 1\|Phase 2
NCT00458315	Rigshospitalet, Denmark	Unknown Primary Tumors	May 2007	Phase 2
NCT02490878	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)\|Genentech, Inc.	Radionecrosis\|Brain Metastases	April 2016	Phase 2
NCT01180959	M.D. Anderson Cancer Center\|Genentech, Inc.\|OSI Pharmaceuticals	Liver Cancer	April 14, 2011	Phase 2
NCT00805064	Johann Wolfgang Goethe University Hospital	Retinal Vein Occlusion	January 2006	Phase 3
NCT00334815	National Cancer Institute (NCI)	Lung Adenocarcinoma\|Lung Adenosquamous Carcinoma\|Lung Large Cell Carcinoma\|Lung Squamous Cell Carcinoma\|Minimally Invasive Lung Adenocarcinoma\|Stage IIIA Lung Non-Small Cell Cancer AJCC v7\|Stage IIIB Lung Non-Small Cell Cancer AJCC v7	June 15, 2006	Phase 2
NCT00461773	Yale University\|Novartis\|Genentech, Inc.	Hormone-Sensitive Breast Cancer\|Breast Cancer	March 2007	Phase 2
NCT04551950	EMD Serono Research & Development Institute, Inc.\|Merck KGaA, Darmstadt, Germany\|EMD Serono	Cervical Cancer	October 19, 2020	Phase 1
NCT02876224	Hoffmann-La Roche	Colorectal Cancer	September 30, 2016	Phase 1
NCT00395434	Mateon Therapeutics	Tumors	September 2006	Phase 1
NCT00356889	National Cancer Institute (NCI)	Cholangiocarcinoma of the Extrahepatic Bile Duct\|Cholangiocarcinoma of the Gallbladder\|Gastrointestinal Cancer\|Recurrent Extrahepatic Bile Duct Cancer\|Recurrent Gallbladder Cancer\|Unresectable Extrahepatic Bile Duct Cancer\|Unresectable Gallbladder Cancer	May 2006	Phase 2
NCT01227707	Hoffmann-La Roche	Colorectal Cancer	November 2005	Phase 2
NCT04511715	Shahid Beheshti University of Medical Sciences	Non-proliferative Diabetic Retinopathy	September 1, 2020	Phase 2\|Phase 3
NCT00635050	University of Alabama at Birmingham\|Ortho Biotech, Inc.\|Genentech, Inc.	Invasive Breast Cancer	March 2008	Phase 2
NCT04595266	Grupo Espanol Multidisciplinario del Cancer Digestivo	Colorectal Cancer Metastatic\|Liver Metastasis Colon Cancer	June 29, 2021	Phase 2
NCT01094184	Hoffmann-La Roche	Breast Cancer	March 2010	Phase 4
NCT05359861	Surface Oncology	Hepatocellular Carcinoma	April 12, 2022	Phase 2
NCT00671645	Austrian Breast & Colorectal Cancer Study Group\|Hoffmann-La Roche	Rectal Cancer	July 2008	Phase 2
NCT01321957	Martin-Luther-Universität Halle-Wittenberg\|Roche Pharma AG	Metastatic Colorectal Cancer	May 2011	Phase 2
NCT01650428	University College, London\|Cancer Research UK\|Hoffmann-La Roche	Rectal Cancer	April 2013	Phase 2
NCT01269853	Northwell Health\|Feinstein Institute for Medical Research	Glioblastoma Multiforme\|Anaplastic Astrocytoma	October 2010	Phase 1\|Phase 2
NCT00083031	Dana-Farber Cancer Institute\|National Cancer Institute (NCI)\|Genentech, Inc.	Breast Cancer	July 2003	Phase 2
NCT00109070	Genentech, Inc.	Colorectal Cancer	September 2000	Phase 3
NCT01055028	Stanford University\|Genentech, Inc.	Angiosarcomas\|Soft Tissue Sarcoma	February 2010	Phase 2
NCT00861419	Amgen	Advanced Solid Tumors	December 2005	Phase 1
NCT02665416	Hoffmann-La Roche	Advanced+Metastatic Solid Tumors	January 25, 2016	Phase 1
NCT00408070	UConn Health\|Genentech, Inc.	Ovarian Cancer\|Peritoneal Cancer\|Fallopian Tube Cancer\|Stage 3 Cancer\|Stage 4 Cancer	October 2006	Phase 2
NCT02841332	University Hospital, Toulouse	Glioblastoma	May 2013	Not Applicable
NCT02256800	Jaw-Yuan Wang, MD, PhD\|Kaohsiung Medical University Chung-Ho Memorial Hospital	Metastatic Colorectal Cancer	August 13, 2014	Not Applicable
NCT00276575	Herbert Hurwitz, MD\|National Cancer Institute (NCI)\|Duke University	Unspecified Adult Solid Tumor, Protocol Specific	March 2005	Phase 1
NCT02743221	Institut de Recherches Internationales Servier\|ADIR, a Servier Group company\|Servier	Metastatic Colorectal Cancer	April 29, 2016	Phase 2
NCT01343901	Hoffmann-La Roche	Colorectal Cancer	September 30, 2010
NCT00782756	Memorial Sloan Kettering Cancer Center\|Genentech, Inc.\|National Institutes of Health (NIH)	Brain Cancer\|Malignant Glioma	October 28, 2008	Phase 2
NCT03170284	Hoffmann-La Roche	Carcinoma, Non-Small-Cell Lung	June 17, 2008
NCT00598156	Lund University Hospital\|Hoffmann-La Roche	Metastatic Colorectal Cancer	June 2007	Phase 3
NCT00464646	NSABP Foundation Inc\|Genentech, Inc.\|International Drug Development Institute	Breast Cancer	May 2007	Phase 2
NCT01951482	Sun Yat-sen University	Non Squamous Non-small Cell Lung Cancer\|Brain Metastases\|Bevacizumab	June 2013	Phase 2
NCT00467142	Institut Bergonié	Colorectal Cancer	January 23, 2007	Phase 2
NCT02007174	Instituto de Oftalmología Fundación Conde de Valenciana\|National Council of Science and Technology, Mexico	Recurrent Pterygium	March 2012
NCT01263834	Prince of Songkla University	Glaucoma	December 2010	Phase 2\|Phase 3
NCT04689347	Fondazione IRCCS Istituto Nazionale dei Tumori, Milano	Metastatic Colorectal Cancer	January 1, 2021	Phase 1
NCT02664961	Tracon Pharmaceuticals Inc.	Gestational Trophoblastic Neoplasia\|Choriocarcinoma\|Placental Site Trophoblastic Tumor\|Epithelioid Trophoblastic Tumor	March 2016	Phase 2
NCT02118831	California Retina Consultants	Age-related Macular Degeneration\|Diabetic Macular Edema\|Retinal Vein Occlusion	March 2012	Phase 1\|Phase 2
NCT03786081	Seagen Inc.\|Genmab\|European Network of Gynaecological Oncological Trial Groups (ENGOT)\|Belgian Gynaecological Oncology Group\|Gynecologic Oncology Group\|Merck Sharp & Dohme LLC	Cervical Cancer	February 27, 2019	Phase 1\|Phase 2
NCT01707745	Sivakami A Pai\|Dubai Health Authority	Stage 2&addition; or Stage 3&addition; Retinopathy of Prematurity in Zone I or Zone II.	January 2010	Not Applicable
NCT00096148	National Cancer Institute (NCI)	Adult Acute Basophilic Leukemia\|Adult Acute Eosinophilic Leukemia\|Adult Acute Megakaryoblastic Leukemia (M7)\|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)\|Adult Acute Monoblastic Leukemia (M5a)\|Adult Acute Monocytic Leukemia (M5b)\|Adult Acute Myeloblastic Leukemia With Maturation (M2)\|Adult Acute Myeloblastic Leukemia Without Maturation (M1)\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myelomonocytic Leukemia (M4)\|Adult Erythroleukemia (M6a)\|Adult Pure Erythroid Leukemia (M6b)\|Childhood Acute Basophilic Leukemia\|Childhood Acute Eosinophilic Leukemia\|Childhood Acute Erythroleukemia (M6)\|Childhood Acute Megakaryocytic Leukemia (M7)\|Childhood Acute Monoblastic Leukemia (M5a)\|Childhood Acute Monocytic Leukemia (M5b)\|Childhood Acute Myeloblastic Leukemia With Maturation (M2)\|Childhood Acute Myeloblastic Leukemia Without Maturation (M1)\|Childhood Acute Myelomonocytic Leukemia (M4)\|Secondary Acute Myeloid Leukemia\|Untreated Adult Acute Myeloid Leukemia\|Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies	October 2004	Phase 2
NCT00691379	Hellenic Oncology Research Group\|University Hospital of Crete	Breast Cancer	April 2008	Phase 1\|Phase 2
NCT00979017	Katy Peters\|Genentech, Inc.\|Duke University	Glioblastoma Multiforme\|Gliosarcoma	November 2009	Phase 2

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References

[1] Tan H, et al. 99mTc-labeled bevacizumab for detecting atherosclerotic plaque linked to plaque neovascularization and monitoring antiangiogenic effects of treatment in ApoE-/-mice. Sci Rep. 2017 Jun 14;7(1):3504.
[2] Wang Q, et al. Pharmacological characteristics and efficacy of a novel anti-angiogenic antibody FD006 in corneal neovascularization. BMC Biotechnol. 2014 Feb 27;14:17.
[3] Di Mauro C, et al. Hedgehog signalling pathway orchestrates angiogenesis in triple-negative breast cancers. Br J Cancer. 2017 May 23;116(11):1425-1435.

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