[CAS NO. 219685-50-4] Eculizumab

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SMILES	[Eculizumab]

NCT Number	Sponsor	Condition	Start Date	Phase
NCT01399593	Alexion Pharmaceuticals	Antibody Mediated Rejection	November 2, 2011	Phase 2
NCT04288713	Hudson Medical	Coronavirus
NCT00122317	Alexion Pharmaceuticals	Paroxysmal Hemoglobinuria, Nocturnal	May 2005	Phase 3
NCT00098280	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Hemoglobinuria, Paroxysmal	December 2004	Phase 3
NCT01221181	Columbia University\|Alexion Pharmaceuticals	Dense Deposit Disease\|Membranoproliferative Glomerulonephritis	July 2010	Phase 1
NCT04103489	Johns Hopkins University\|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	HELLP Syndrome (HELLP), Third Trimester\|Complement Abnormality\|Morbidity;Newborn\|Maternal Injury\|Preeclampsia Severe	February 23, 2021	Phase 1
NCT04558918	Novartis Pharmaceuticals\|Novartis	Paroxysmal Nocturnal Hemoglobinuria (PNH)	January 25, 2021	Phase 3
NCT01303952	University Hospital, Essen\|Alexion Pharmaceuticals	Cold Agglutinin Disease	January 2011	Phase 2
NCT03818607	Amgen	Paroxysmal Nocturnal Hemoglobinuria	April 24, 2019	Phase 3
NCT01410916	Alexion Pharmaceuticals	Shiga-like Toxin-producing Escherichia Coli	July 2011	Phase 2\|Phase 3
NCT01919346	Heeger, Peter, M.D.\|Alexion Pharmaceuticals\|Icahn School of Medicine at Mount Sinai	Delayed Graft Function\|Kidney Transplantation\|Complement Activity	August 2013	Phase 2
NCT04320602	Alexion Pharmaceuticals	Paroxysmal Nocturnal Hemoglobinuria	March 26, 2021	Phase 4
NCT00122304	Alexion Pharmaceuticals	Hemoglobinuria, Paroxysmal	December 2004	Phase 3
NCT03722329	Samsung Bioepis Co., Ltd.	Healthy	November 13, 2018	Phase 1
NCT01997229	Alexion Pharmaceuticals	Refractory Generalized Myasthenia Gravis	December 2013	Phase 3
NCT00844844	Alexion Pharmaceuticals	Atypical Hemolytic Uremic Syndrome	May 2009	Phase 2
NCT00844545	Alexion Pharmaceuticals	Atypical Hemolytic Uremic Syndrome	May 2009	Phase 2
NCT00438789	Alexion Pharmaceuticals	Hemoglobinuria, Paroxysmal
NCT04155424	Alexion Pharmaceuticals	Neuromyelitis Optica\|Neuromyelitis Optica Spectrum Disorder	January 14, 2020	Phase 2\|Phase 3
NCT01403389	Schroppel, Bernd, M.D.\|Alexion Pharmaceuticals	Delayed Function of Renal Transplant	December 1, 2011	Phase 2
NCT01895127	Brigham and Women´s Hospital\|Alexion Pharmaceuticals	Antibody-mediated Rejection\|Humoral Rejection	November 2013	Phase 2
NCT04355494	Alexion Pharmaceuticals	COVID-19\|Pneumonia, Viral\|Acute Lung Injury+Acute Respiratory Distress Syndrome (ARDS)
NCT00727194	Alexion Pharmaceuticals	Myasthenia Gravis	October 2008	Phase 2
NCT00670774	Mark Stegall\|Alexion Pharmaceuticals\|Mayo Clinic	Kidney Transplant	March 2008	Phase 1\|Phase 2
NCT00935883	Philip J. Rosenfeld, MD, PhD\|Alexion Pharmaceuticals\|University of Miami	Age-Related Macular Degeneration	July 2009	Phase 2
NCT04079257	Radboud University Medical Center	Paroxysmal Nocturnal Hemoglobinuria\|Eculizumab\|PK-PD	February 23, 2021
NCT03468140	Yale University\|Ochsner Health System\|Alexion Pharmaceuticals	End Stage Liver Disease	October 1, 2021	Early Phase 1
NCT02145182	Alexion Pharmaceuticals\|CTI Clinical Trial and Consulting Services	Delayed Graft Function	August 21, 2014	Phase 2\|Phase 3
NCT01892345	Alexion Pharmaceuticals	Neuromyelitis Optica\|Neuromyelitis Optica Spectrum Disorder	April 11, 2014	Phase 3
NCT01757431	Alexion Pharmaceuticals	Atypical Hemolytic Uremic Syndrome (aHUS)	May 16, 2012	Phase 2
NCT04679103	AO GENERIUM	Paroxysmal Nocturnal Hemoglobinuria	May 3, 2018	Phase 3
NCT00130000	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Paroxysmal Hemoglobinuria, Nocturnal	August 9, 2005	Phase 3
NCT01756508	Russian Academy of Medical Sciences	End-Stage Renal Disease\|Kidney Failure\|Graft Reperfusion Injury	September 1, 2012	Phase 2
NCT02493725	Chiba University\|Japan Agency for Medical Research and Development	Gullain Barre Syndrome	July 2015	Phase 2
NCT00838513	Alexion Pharmaceuticals	Atypical Hemolytic Uremic Syndrome	July 2009	Phase 2
NCT03950804	Marmara University\|National Institute of Allergy and Infectious Diseases (NIAID)	CD55 - Cluster of Differentiation Antigen 55 Deficiency\|Primary Intestinal Lymphangiectasis\|Protein-Losing Enteropathies\|Complement Regulatory Factor Defect	June 15, 2018
NCT02298933	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Thrombocytopenia\|Alloimmune Platelet Refractoriness	November 21, 2014	Phase 2
NCT01579838	Hadassah Medical Organization	Chronic Hemolysis	February 2012	Phase 1\|Phase 2
NCT04346797	Assistance Publique - Hôpitaux de Paris	SARS-CoV-2\|COVID19	April 16, 2020	Phase 2
NCT04752566	Alexion Pharmaceuticals	Guillain-Barre Syndrome	March 8, 2021	Phase 3
NCT05131204	Regeneron Pharmaceuticals	Paroxysmal Nocturnal Hemoglobinuria	March 31, 2022	Phase 3
NCT00904826	Mayo Clinic\|Alexion Pharmaceuticals	Neuromyelitis Optica\|Devic´s Disease	April 2009	Phase 1\|Phase 2
NCT02093533	Mario Negri Institute for Pharmacological Research\|Alexion Pharma Italy s.r.l.	Membranoproliferative Glomerulonephritis	March 2014	Phase 2
NCT01106027	Mayo Clinic\|Alexion Pharmaceuticals	Kidney Transplant	March 2010	Phase 1\|Phase 2
NCT03759366	Alexion Pharmaceuticals	Myasthenia Gravis\|Myasthenia Gravis, Juvenile Form\|Myasthenia Gravis, Generalized	December 21, 2018	Phase 3
NCT05116774	BioCryst Pharmaceuticals	Paroxysmal Nocturnal Hemoglobinuria (PNH)	December 6, 2021	Phase 2
NCT02205541	University Hospital, Toulouse	Hemolytic Uremic Syndrome of Childhood	June 2015	Phase 3
NCT02013037	Cedars-Sinai Medical Center\|Alexion Pharmaceuticals	Antibody-mediated Rejection\|Hyperacute Rejection of Cardiac Transplant\|Left Ventricular Dysfunction\|Cardiac Allograft Vasculopathy\|Heart Graft Dysfunction	November 2012	Phase 3
NCT00122330	Alexion Pharmaceuticals	Hemoglobinuria, Paroxysmal	October 2004	Phase 3
NCT01192399	Alexion Pharmaceuticals	Paroxysmal Nocturnal Hemoglobinuria	November 2007	Phase 2
NCT03472885	Alexion Pharmaceuticals\|Achillion, a wholly owned subsidiary of Alexion	Paroxysmal Nocturnal Hemoglobinuria (PNH)	May 8, 2018	Phase 2
NCT04432584	Hoffmann-La Roche\|Chugai Pharmaceutical	Paroxysmal Nocturnal Hemoglobinuria	September 30, 2020	Phase 3
NCT03056040	Alexion Pharmaceuticals	Paroxysmal Nocturnal Hemoglobinuria (PNH)	June 5, 2017	Phase 3
NCT01275287	University of North Carolina, Chapel Hill\|Alexion Pharmaceuticals\|National Institutes of Health (NIH)\|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	May 2011	Phase 2
NCT02604420	Weill Medical College of Cornell University	Thrombotic Microangiopathy\|Disorder Related to Bone Marrow Transplantation	September 2014
NCT04802083	Alexion Pharmaceuticals	Covid19
NCT02003144	Alexion Pharmaceuticals	Neuromyelitis Optica\|Neuromyelitis Optica Spectrum Disorder	January 12, 2015	Phase 3
NCT04725812	Cedars-Sinai Medical Center\|Alexion Pharmaceuticals	Preeclampsia\|Severe Preeclampsia\|Eculizumab\|HELLP\|HELLP Syndrome\|HELLP Syndrome Second Trimester\|Pregnancy Related\|AHUS\|PNH\|Complement Regulatory Factor Defect\|Complement Abnormality\|HELLP Syndrome Third Trimester	September 13, 2021	Phase 2
NCT02029378	NHS Greater Glasgow and Clyde\|University of Glasgow	Gullian Barre Syndrome	September 2014	Phase 2
NCT01327573	Sanjay Kulkarni\|Alexion Pharmaceuticals\|Yale University	Kidney; Complications, Allograft	March 2011	Phase 1
NCT01194973	Alexion Pharmaceuticals	Atypical Hemolytic-Uremic Syndrome	July 2010	Phase 2
NCT04058158	Samsung Bioepis Co., Ltd.	Paroxysmal Nocturnal Hemoglobinuria	August 7, 2019	Phase 3
NCT02727608	Uppsala University	Diabetes Mellitus	May 15, 2016	Phase 2
NCT04859608	University Hospital, Tours\|Centre Hospitalier Universitaire, Amiens\|University Hospital, Angers\|Centre Hospitalier Universitaire de Besancon\|University Hospital, Caen\|Centre Hospitalier of Chartres\|Nantes University Hospital\|University of Nancy\|Poitiers University Hospital\|Rennes University Hospital\|University Hospital, Rouen\|University Hospital, Strasbourg, France\|Centre Hospitalier Universitaire de Nice\|Hôpital Necker-Enfants Malades\|Tenon Hospital, Paris\|University Hospital, Lille\|Reims University Hospital\|University Hospital, Clermont-Ferrand\|Assistance Publique Hopitaux De Marseille\|Hospices Civils de Lyon	Hemolytic-Uremic Syndrome, Atypical	November 1, 2021	Phase 4
NCT00112983	Jonsson Comprehensive Cancer Center\|National Cancer Institute (NCI)	Leukemia	November 2004	Phase 3
NCT04935177	Hansa Biopharma AB	Kidney Transplantation in Highly Sensitized Patients	October 14, 2021	Phase 3
NCT00485576	Alexion Pharmaceuticals	Allergic Asthma	September 2007	Phase 2
NCT03518203	Children´s Hospital Medical Center, Cincinnati	Thrombotic Microangiopathies\|Atypical Hemolytic Uremic Syndrome\|Multiple Organ Dysfunction Syndrome	August 3, 2018	Phase 2
NCT04434092	Hoffmann-La Roche\|Chugai Pharmaceutical	Paroxysmal Nocturnal Hemoglobinuria	October 8, 2020	Phase 3
NCT01567085	Alexion Pharmaceuticals	Stage V Chronic Kidney Disease	August 29, 2012	Phase 2
NCT02574403	Nantes University Hospital	Atypical Hemolytic Uremic Syndrome	November 2015	Phase 4
NCT02614898	Alexion Pharmaceuticals	Atypical Hemolytic Uremic Syndrome	November 4, 2015
NCT01194804	Alexion Pharmaceuticals\|CMIC Co, Ltd. Japan	Paroxysmal Nocturnal Hemoglobinuria	April 2008	Phase 2
NCT02113891	Assistance Publique - Hôpitaux de Paris\|Institut National de la Santé Et de la Recherche Médicale, France\|Alexion Pharmaceuticals	Subclinical Acute Antibody-mediated Rejection in Kidney Transplantation	February 2015	Phase 1\|Phase 2
NCT02301624	Alexion Pharmaceuticals	Refractory Generalized Myasthenia Gravis	November 12, 2014	Phase 3
NCT01095887	Mayo Clinic\|Alexion Pharmaceuticals	Kidney Transplant	May 2010	Phase 1\|Phase 2
NCT00844428	Alexion Pharmaceuticals	Atypical Hemolytic Uremic Syndrome	July 2009	Phase 2
NCT01193348	Alexion Pharmaceuticals	Atypical Hemolytic-Uremic Syndrome	September 2010	Phase 2
NCT00867932	Alexion Pharmaceuticals	Hemoglobinuria, Paroxysmal	October 2, 2009	Phase 4
NCT01029587	Johns Hopkins University	Antiphospholipid Antibody Syndrome\|End Stage Renal Disease	November 2009	Phase 2
NCT02946463	Alexion Pharmaceuticals	Paroxysmal Nocturnal Hemoglobinuria (PNH)	December 20, 2016	Phase 3

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Catalog:	HY-P9914
Brand:	MCE
CAS:	219685-50-4

[CAS NO. 219685-50-4] Eculizumab

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