[CAS NO. 221174-33-0]  GlyoxalaseIinhibitor

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PRODUCTS SPECIFICATIONS [221174-33-0]

Catalog
HY-15167
Brand
MCE
CAS
221174-33-0

DESCRIPTION [221174-33-0]

Overview

MDL-
Molecular Weight613.91
Molecular FormulaC21H30BrClN4O8S
SMILESBrC1=CC=C(N(O)C(SC[C@H](NC(CC[C@H](N)C(OCC)=O)=O)C(NCC(OCC)=O)=O)=O)C=C1.[H]Cl

For research use only. We do not sell to patients.


Summary

Glyoxalase I inhibitor is a potent Glyoxalase I inhibitor, candidate for anticancer agents.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)


Solvent & Solubility

In Vitro:

DMSO : ≥ 37 mg/mL ( 60.27 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6289 mL 8.1445 mL 16.2890 mL
5 mM 0.3258 mL 1.6289 mL 3.2578 mL
10 mM 0.1629 mL 0.8145 mL 1.6289 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (4.07 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (4.07 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (4.07 mM); Clear solution

* All of the co-solvents are available by MCE.