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[CAS NO. 22246-18-0] 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-W010130 |
| Brand: | MCE |
| CAS: | 22246-18-0 |
Overview
| MDL | MFCD06410891 |
|---|---|
| Molecular Weight | 163.17 |
| Molecular Formula | C9H9NO2 |
| SMILES | O=C1NC2=C(C=CC(O)=C2)CC1 |
Summary
IC50 & Target
IC50: 183 μM (MAO-A) [1]
In Vitro
7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 612.86 mM ; Need ultrasonic)
H 2 O : 1 mg/mL ( 6.13 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 6.1286 mL | 30.6429 mL | 61.2858 mL |
| 5 mM | 1.2257 mL | 6.1286 mL | 12.2572 mL |
| 10 mM | 0.6129 mL | 3.0643 mL | 6.1286 mL |
-
1.
-
2.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.5 mg/mL (15.32 mM); Clear solution
-
3.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.5 mg/mL (15.32 mM); Clear solution
-
4.
Add each solvent one by one: PBS
Solubility: 1 mg/mL (6.13 mM); Clear solution; Need ultrasonic
Synonyms
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