[CAS NO. 223777-16-0] 2'-O-(2-Methoxyethyl)-cytidine

Ships within

Stock

Price

Qty

Total

$0.00

Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis

request a quote

If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [223777-16-0]

Catalog

HY-W048496

Brand

MCE

CAS

223777-16-0

DESCRIPTION [223777-16-0]

Overview

MDL	MFCD17215637
Molecular Weight	301.30
Molecular Formula	C12H19N3O6
SMILES	O[C@H]1[C@@H](OCCOC)[C@H](N2C(N=C(N)C=C2)=O)O[C@@H]1CO

For research use only. We do not sell to patients.

Summary

2'-O-(2-Methoxyethyl)-cytidine is a synthetic oligonucleotide conversed from uridine. 2'-O-(2-Methoxyethyl)-uridine has the potential for chemotherapeutic agents development ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL ( 829.74 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3190 mL	16.5948 mL	33.1895 mL
5 mM	0.6638 mL	3.3190 mL	6.6379 mL
10 mM	0.3319 mL	1.6595 mL	3.3190 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.08 mg/mL (6.90 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.08 mg/mL (6.90 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.08 mg/mL (6.90 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] UrtziLegorburu, et al. Conversion of uridine into 2′-O-(2-methoxyethyl)uridine and 2′-O-(2-methoxyethyl)cytidine. Tetrahedron

Synonyms

Cytidine, 2′-O-(2-methoxyethyl)-

2′-O-(2-Methoxyethyl)cytidine