[CAS NO. 22419-74-5] Incensole

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PRODUCTS SPECIFICATIONS [22419-74-5]

Catalog

HY-N4097

Brand

MCE

CAS

22419-74-5

DESCRIPTION [22419-74-5]

Overview

MDL	-
Molecular Weight	306.48
Molecular Formula	C20H34O2
SMILES	O[C@@H]1[C@@](O2)(C)CC[C@@]2(C(C)C)C/C=C(C)/CC/C=C(C)/CC1

For research use only. We do not sell to patients.

Summary

Incensole, a 14-membered diterpenoid, is isolated from both essential oils and resins of frankincense. Incensole has shown anti-inflammatory and anti-depression activities due to their ability to activate ion channels in the brain to alleviate anxiety or depression ^[1] .

Appearance

Liquid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL ( 815.71 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.2629 mL	16.3143 mL	32.6286 mL
5 mM	0.6526 mL	3.2629 mL	6.5257 mL
10 mM	0.3263 mL	1.6314 mL	3.2629 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.08 mg/mL (6.79 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.08 mg/mL (6.79 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Al-Harrasi A, et al. Distribution of the anti-inflammatory and anti-depressant compounds: Incensole and incensole acetate in genus Boswellia. Phytochemistry. 2019 May;161:28-40.

Synonyms

15-Oxabicyclo[10.2.1]pentadeca-5,9-dien-2-ol, 1,5,9-trimethyl-12-(1-methylethyl)-, (1R,2S,5E,9E,12S)-

15-Oxabicyclo[10.2.1]pentadeca-5,9-dien-2-ol, 12-isopropyl-1,5,9-trimethyl-

(1R,2S,5E,9E,12S)-1,5,9-Trimethyl-12-(1-methylethyl)-15-oxabicyclo[10.2.1]pentadeca-5,9-dien-2-ol

Incensol

Incensole