[CAS NO. 2245020-50-0] AB-506

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PRODUCTS SPECIFICATIONS [2245020-50-0]

Catalog

HY-148768

Brand

MCE

CAS

2245020-50-0

DESCRIPTION [2245020-50-0]

Overview

MDL	-
Molecular Weight	461.85
Molecular Formula	C21H18ClF2N5O3
SMILES	ClC(C=C1NC(C2=C3C([C@H](CC3)NC(OCC4=NN(C)C=N4)=O)=C(C=C2)F)=O)=C(C=C1)F

For research use only. We do not sell to patients.

Summary

AB-506 is an orally active inhibitor of HBV replication targeting the viral core protein. AB-506 can bind to HBV core protein, accelerate capsid assembly and inhibit HBV pgRNA encapsidation. AB-506 can be used in chronic hepatitis B (CHB) research ^[1] .

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References

[1] Nagraj Mani, et al. Preclinical characterization of AB-506, an inhibitor of HBV replication targeting the viral core protein. Antiviral Res. 2022 Jan;197:105211.