[CAS NO. 22467-07-8] Gymnemagenin

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Catalog:	HY-N2268
Brand:	MCE
CAS:	22467-07-8

Overview

MDL	MFCD06656306
Molecular Weight	506.71
Molecular Formula	C30H50O6
SMILES	OC[C@]1([C@H]2O)[C@](CC(C)(C)[C@H]2O)([H])C3=CC[C@@]4([H])[C@@](C)(CC[C@]5([H])[C@@]4(CC[C@H](O)[C@@]5(C)CO)C)[C@]3(C)C[C@@H]1O

For research use only. We do not sell to patients.

Summary

Gymnemagenin is a triterpenoid isolated from G. sylvestre . Gymnemagenin is an agent for diabetes and obesity and also possesses antiviral properties ^[1] ^[2] .

In Vivo

Gymnemagenin has a poor oral bioavailability (~ 14 %) in rats ^[2] .
Gymnemagenin has a short half-life and a high clearance in rats ^[2] .
Gymnemagenin metabolizes rapidly with a short apparent and intrinsic half-life (~ 7 min) and high intrinsic clearance ^[2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Source

Plants
Asclepiadaceae
Gymnema sylvestre (Retz.) Schult.

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

References

[1] Parthasarathy R, et al. Gymnemagenin-producing endophytic fungus isolated from a medicinal plant Gymnema sylvestre R.Br. Appl Biochem Biotechnol. 2014 Mar;172(6):3141-52.
[2] In Vitro Metabolic Stability and Permeability of Gymnemagenin and Its In Vivo Pharmacokinetic Correlation in Rats - A Pilot Study.

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