[CAS NO. 2253879-65-9] BCL6-IN-4
PRODUCTS SPECIFICATIONS [2253879-65-9]
DESCRIPTION [2253879-65-9]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 503.04 |
| Molecular Formula | C25H35ClN6O3 |
| SMILES | O=C1N(CCC(C)(O)C)C2=CC(NC3=NC(N4CC(C)(C)OC(C)(C)C4)=NC=C3Cl)=CC=C2N1C |
Summary
BCL6-IN-4 is a potent B-cell lymphoma 6 (BCL6) inhibitor with an IC 50 of 97 nM. BCL6-IN-4 has anti-tumor activities [1] .
IC50 & Target
IC50: 97 nM (BCL6) [1]
In Vitro
BCL6-IN-4 (compound 25b) inhibits OCI-Ly1 and OCI-Ly3 cell lines growth with GI 50 values of 2.8 μM and 4.2 μM, respectively [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 73.33 mg/mL ( 145.77 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.9879 mL | 9.9396 mL | 19.8791 mL |
| 5 mM | 0.3976 mL | 1.9879 mL | 3.9758 mL |
| 10 mM | 0.1988 mL | 0.9940 mL | 1.9879 mL |
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1.