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[CAS NO. 2285446-67-3] (E/Z)-E64FC26
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-122895A |
| Brand: | MCE |
| CAS: | 2285446-67-3 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 340.38 |
| Molecular Formula | C19H23F3O2 |
| SMILES | OC1=CC2=C(/C(C=C2C(F)(F)F)=C/CCCCCCCC)C=C1O |
Summary
(E/Z)-E64FC26 is a mixture complex of E-E64FC26 and Z-E64FC26. E64FC26 (E-E64FC26) is a potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC 50 s of 1.9, 20.9, 25.9, 16.3, and 25.4 μM against PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6. E64FC26 shows anti-myeloma activity [1] [2] .
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 293.79 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.9379 mL | 14.6895 mL | 29.3789 mL |
| 5 mM | 0.5876 mL | 2.9379 mL | 5.8758 mL |
| 10 mM | 0.2938 mL | 1.4689 mL | 2.9379 mL |
-
1.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: 2.5 mg/mL (7.34 mM); Suspended solution; Need ultrasonic
References
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