[CAS NO. 2301085-04-9]  Emzadirib

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PRODUCTS SPECIFICATIONS [2301085-04-9]

Catalog
HY-111887
Brand
MCE
CAS
2301085-04-9

DESCRIPTION [2301085-04-9]

Overview

MDL-
Molecular Weight580.76
Molecular FormulaC27H40N4O6S2
SMILESCC(OC(N[C@H]1CC[C@H](C2=NC=C(C3=CC=C(NC(OC(C)C)=O)C=C3S(=O)(NC(C)(C)C)=O)S2)CC1)=O)C

For research use only. We do not sell to patients.

Summary

RAD51-IN-2 (compound example 67A) is a RAD51 inhibitor extracted from patent WO2019/051465A1 [1] .


IC50 & Target

RAD51 [1]


In Vitro

RAD51-IN-2 exhibts an EC 50 of ≤1 μM in activation-induced cytidine deaminase (AID) positive cells [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 172.19 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7219 mL 8.6094 mL 17.2188 mL
5 mM 0.3444 mL 1.7219 mL 3.4438 mL
10 mM 0.1722 mL 0.8609 mL 1.7219 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (4.30 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (4.30 mM); Clear solution

* All of the co-solvents are available by MCE.