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[CAS NO. 2361742-30-3] VPC-70619
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-144878 |
| Brand: | MCE |
| CAS: | 2361742-30-3 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 364.71 |
| Molecular Formula | C16H8ClF3N4O |
| SMILES | N#CC1=CC(C(F)(F)F)=C(C=C1)NNC(C2=CC=C(C(Cl)=C2)C#N)=O |
Summary
VPC-70619 is a potent, orally active N-Myc inhibitor. VPC-70619 blocks the N-Myc-Max heterocomplex from binding to DNA E-boxes and demonstrated strong inhibition activity against N-Myc-dependent cell lines as well as high bioavailability in both oral and intraperitoneal administration [1] .
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : ≥ 100 mg/mL ( 274.19 mM )
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.7419 mL | 13.7095 mL | 27.4190 mL |
| 5 mM | 0.5484 mL | 2.7419 mL | 5.4838 mL |
| 10 mM | 0.2742 mL | 1.3710 mL | 2.7419 mL |
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