[CAS NO. 2375815-63-5] CD73-IN-3
PRODUCTS SPECIFICATIONS [2375815-63-5]
DESCRIPTION [2375815-63-5]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 286.33 |
| Molecular Formula | C15H18N4O2 |
| SMILES | CC([C@@H]1[C@](C(C=C(C(C(N2)=O)=CNC2=O)N=N3)=C3C)([H])C1)C |
Summary
In Vitro
CD73-IN-3 inhibits CD73 activity in human serum with an EC
50
of 0.213 μM. CD73-IN-3 inhibits CD73 activity in human serum by 56.8%, 71.7% and 76.9% at 0.52 μM, 1.56 μM, 4.68 μM,respectively
[1]
.
In Calu6 human cell assay against CD73, the IC
50
for CD73-IN-3 against CD73 is 0.0073 uM
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 349.25 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.4925 mL | 17.4624 mL | 34.9247 mL |
| 5 mM | 0.6985 mL | 3.4925 mL | 6.9849 mL |
| 10 mM | 0.3492 mL | 1.7462 mL | 3.4925 mL |