MDL | - |
---|---|
Molecular Weight | 522.64 |
Molecular Formula | C27H31FN6O2S |
SMILES | O=C(C1=CC=C(C2=CCCC2)S1)NC3=CC=C(NC4=NC(N5C[C@@H](C)N[C@@H](C)C5)=NC=C4F)C=C3OC |
BCL6-IN-6 is a potent inhibitor of transcriptional repressor B-cell lymphoma 6 ( BCL6 ). BCL6-IN-6 significantly blocks the interaction of BCL6 with its corepressors and reactivates BCL6 target genes in a dose-dependent manner. BCL6-IN-6 has the potential for the research of diffuse large B-cell lymphoma (DLBCL) [1] .
BCL6 [1]
Solid
Room temperature in continental US; may vary elsewhere.
Powder | -20°C | 3 years |
---|---|---|
4°C | 2 years | |
In solvent | -80°C | 6 months |
-20°C | 1 month |
DMSO : ≥ 4 mg/mL ( 7.65 mM )
* "≥" means soluble, but saturation unknown.
Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
---|
1 mM | 1.9134 mL | 9.5668 mL | 19.1336 mL |
5 mM | 0.3827 mL | 1.9134 mL | 3.8267 mL |
10 mM | --- | --- | --- |