[CAS NO. 2408882-54-0]  BCL6-IN-6

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PRODUCTS SPECIFICATIONS [2408882-54-0]

Catalog
HY-143653
Brand
MCE
CAS
2408882-54-0

DESCRIPTION [2408882-54-0]

Overview

MDL-
Molecular Weight522.64
Molecular FormulaC27H31FN6O2S
SMILESO=C(C1=CC=C(C2=CCCC2)S1)NC3=CC=C(NC4=NC(N5C[C@@H](C)N[C@@H](C)C5)=NC=C4F)C=C3OC

For research use only. We do not sell to patients.

Summary

BCL6-IN-6 is a potent inhibitor of transcriptional repressor B-cell lymphoma 6 ( BCL6 ). BCL6-IN-6 significantly blocks the interaction of BCL6 with its corepressors and reactivates BCL6 target genes in a dose-dependent manner. BCL6-IN-6 has the potential for the research of diffuse large B-cell lymphoma (DLBCL) [1] .


IC50 & Target

BCL6 [1]


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 4 mg/mL ( 7.65 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9134 mL 9.5668 mL 19.1336 mL
5 mM 0.3827 mL 1.9134 mL 3.8267 mL
10 mM --- --- ---
* Please refer to the solubility information to select the appropriate solvent.