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[CAS NO. 2408882-54-0] BCL6-IN-6
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-143653 |
| Brand: | MCE |
| CAS: | 2408882-54-0 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 522.64 |
| Molecular Formula | C27H31FN6O2S |
| SMILES | O=C(C1=CC=C(C2=CCCC2)S1)NC3=CC=C(NC4=NC(N5C[C@@H](C)N[C@@H](C)C5)=NC=C4F)C=C3OC |
Summary
BCL6-IN-6 is a potent inhibitor of transcriptional repressor B-cell lymphoma 6 ( BCL6 ). BCL6-IN-6 significantly blocks the interaction of BCL6 with its corepressors and reactivates BCL6 target genes in a dose-dependent manner. BCL6-IN-6 has the potential for the research of diffuse large B-cell lymphoma (DLBCL) [1] .
IC50 & Target
BCL6 [1]
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : ≥ 4 mg/mL ( 7.65 mM )
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.9134 mL | 9.5668 mL | 19.1336 mL |
| 5 mM | 0.3827 mL | 1.9134 mL | 3.8267 mL |
| 10 mM | --- | --- | --- |
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