[CAS NO. 2413944-70-2] USP7-797
PRODUCTS SPECIFICATIONS [2413944-70-2]
DESCRIPTION [2413944-70-2]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 510.05 |
| Molecular Formula | C27H28ClN3O3S |
| SMILES | O=C(N1CC2=CC3=NC=CC(C4=CC(Cl)=CC(C)=C4C[C@@H]5CNCCO5)=C3S2)C6C(C)(C)C6C1=O |
Summary
In Vitro
USP7-IN-7 (0-1 μM) shows cytotoxicity against p53 wild-type blood cancer cell lines with CC
50
values of 0.2, 0.2, 0.4 and 0.1 μM for M07e, OCI-AML5, MOLM13 and MM.IS, respectively
[1]
.
USP7-IN-7 (0-2 μM) shows cytotoxicity against p53 wild-type neuroblastoma cell lines with CC
50
values of 1.9, 0.6 and 0.5 μM for SH-SY5Y, CHP-134 and NB-1, respectively
[1]
.
USP7-IN-7 (0-25 μM) shows cytotoxicity against p53-mutant cancer cell lines with CC
50
values of 0.5, 0.2 and 0.2 μM for H526, LA-N-2 and SK-N-DZ, respectively
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.