[CAS NO. 2416022-90-5] DDR1-IN-5
PRODUCTS SPECIFICATIONS [2416022-90-5]
DESCRIPTION [2416022-90-5]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 434.37 |
| Molecular Formula | C22H13F3N6O |
| SMILES | CC1=C(C#CC2=CN=C3N2N=CC=C3)C4=C(C=C1)C(NC5=CN=CC(C(F)(F)F)=C5)=NO4 |
Summary
DDR1-IN-5 is a selective Discoidin Domain Receptor family, member 1 (DDR1) inhibitor with an IC 50 of 7.36 nM. DDR1-IN-5 inhibits auto-phosphorylation DDR1b (Y513) with an IC 50 of 4.1 nM. DDR1-IN-5 has anti-cancer activity [1] .
IC50 & Target
|
DDR1 7.36 nM (IC 50 ) |
In Vitro
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 2.78 mg/mL ( 6.40 mM ; ultrasonic and warming and heat to 60°C)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.3022 mL | 11.5109 mL | 23.0218 mL |
| 5 mM | 0.4604 mL | 2.3022 mL | 4.6044 mL |
| 10 mM | --- | --- | --- |