[CAS NO. 2417395-15-2] Sevasemten

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PRODUCTS SPECIFICATIONS [2417395-15-2]

Catalog

HY-148799

Brand

MCE

CAS

2417395-15-2

DESCRIPTION [2417395-15-2]

Overview

MDL	-
Molecular Weight	381.28
Molecular Formula	C16H11F4N5O2
SMILES	O=C1C=CC(C2=CN=C(OCC(F)(F)F)N=C2)=NN1CC3=CC(F)=CN=C3

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Summary

Sevasemten is an allosteric inhibitor of skeletal muscle myosin . Sevasemten exhibits selectively myosin inhibition with IC ₅₀ s of ≤10 μM (skeletal), >100 μM (cardiac), respectively ^[1] ^[2] .

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Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1] Russell Alan, et al. Preparation of substituted pyridazinones for use in the treatment of neuromuscular diseases: World Intellectual Property Organization, WO2021231615. 2021-11-18.
[2] WHO Drug Information-World Health Organization (WHO).