[CAS NO. 2438-80-4] (-)-Fucose
PRODUCTS SPECIFICATIONS [2438-80-4]
DESCRIPTION [2438-80-4]
Overview
| MDL | MFCD00135607 |
|---|---|
| Molecular Weight | 164.16 |
| Molecular Formula | C6H12O5 |
| SMILES | O=C[C@H]([C@@H]([C@@H]([C@H](C)O)O)O)O |
Summary
(-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions.
IC50 & Target
|
Human Endogenous Metabolite |
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date | Phase |
|---|---|---|---|---|
| NCT05462587 | Avalo Therapeutics, Inc. |
Leukocyte Adhesion Deficiency
|
July 28, 2022 | Phase 3 |
| NCT03354533 | Orpha Labs |
Leukocyte Adhesion Deficiency, Type II
|
January 1, 2012 | Phase 1|Phase 2 |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
H 2 O : 100 mg/mL ( 609.16 mM ; Need ultrasonic)
DMSO : 50 mg/mL ( 304.58 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 6.0916 mL | 30.4581 mL | 60.9162 mL |
| 5 mM | 1.2183 mL | 6.0916 mL | 12.1832 mL |
| 10 mM | 0.6092 mL | 3.0458 mL | 6.0916 mL |
-
1.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (609.16 mM); Clear solution; Need ultrasonic
-
2.
-
3.
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.5 mg/mL (15.23 mM); Clear solution
-
4.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.5 mg/mL (15.23 mM); Clear solution
Synonyms