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[CAS NO. 2443966-90-1] (+)-SHIN1
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-112066A |
| Brand: | MCE |
| CAS: | 2443966-90-1 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 400.47 |
| Molecular Formula | C24H24N4O2 |
| SMILES | OCC1=CC(C2=CC=CC=C2)=CC([C@@]3(C(C(C)=NN4)=C4OC(N)=C3C#N)C(C)C)=C1 |
1 Publications Citing Use of MCE
Summary
(+)-SHIN1 ((+)-RZ-2994) is an active (+) enantiomer of SHIN1 [1] .
In Vitro
(+)-SHIN1 ((+)-RZ-2994) is potent against cytosolic SHMT1 with an IC 50 for blocking growth of less than 50 nM and 870 nM in SHMT2 deletion cells and HCT-116 cells, respectively [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : ≥ 100 mg/mL ( 249.71 mM )
* "≥" means soluble, but saturation unknown.
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.4971 mL | 12.4853 mL | 24.9707 mL |
| 5 mM | 0.4994 mL | 2.4971 mL | 4.9941 mL |
| 10 mM | 0.2497 mL | 1.2485 mL | 2.4971 mL |
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