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Catalog: | HY-N7634 |
Brand: | MCE |
CAS: | 24449-39-6 |
MDL | - |
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Molecular Weight | 450.53 |
Molecular Formula | C30H26O4 |
SMILES | OC1=C(C=CC=C2)C2=C(O3)C(C=CC3(C)C)=C1C4=C(C=CC5(C)C)C(O5)=C6C(C=CC=C6)=C4O |
Tectol, isolated from Lippia sidoides , exhibits significant activity against human leukemia cell lines HL60 and CEM [1] . Tectol is a farnesyltransferase (FTase) inhibitor with IC 50 s of 2.09 and 1.73 μM for human and T. brucei FTase, respectively. Tectol inhibits drug-resistant strain of P. falciparum (FcB1) with an IC 50 of 3.44 μM [1] [2] .
Plasmodium
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Solid
Room temperature in continental US; may vary elsewhere.
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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