[CAS NO. 2642162-06-7] MrgprX2antagonist-1
PRODUCTS SPECIFICATIONS [2642162-06-7]
DESCRIPTION [2642162-06-7]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 410.36 |
| Molecular Formula | C15H15F5N4O2S |
| SMILES | FC(F)(F)[C@H](O)CN(CC)C(NC1=NN=C(S1)CC2=CC(F)=CC(F)=C2)=O |
Summary
MrgprX2 antagonist-1 is an MrgprX2 antagonist extracted from patent WO2021092264A1, example E23. MrgprX2 antagonist-1 can be used for the research of inflammatory disorders of the skin [1] .
IC50 & Target
MrgprX2 [1]
In Vitro
MRGPRX2, a member of the Mas-related gene family, was found to be expressed in sensory neurons, mast cells and, most recently, in keratinocytes. MRGPRX2 mRNA is present in adipose tissue, esophagus, urinary bladder, lungs with the highest levels found in skin. Activation of MRGPRX2 leads to mast cell degranulation with subsequent pseudo-allergic reactions [2] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
References