[CAS NO. 267402-71-1]  Myoseverin

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PRODUCTS SPECIFICATIONS [267402-71-1]

Catalog
HY-W008956
Brand
MCE
CAS
267402-71-1

DESCRIPTION [267402-71-1]

Overview

MDLMFCD02683596
Molecular Weight432.52
Molecular FormulaC24H28N6O2
SMILESCC(N1C=NC2=C(NCC3=CC=C(OC)C=C3)N=C(NCC4=CC=C(OC)C=C4)N=C12)C

For research use only. We do not sell to patients.

Summary

Myoseverina, a microtubule-binding molecule, induces the reversible fission of multinucleated myotubes into mononucleated fragments. Myoseverina affects the expression of a variety of growth factor, immunomodulatory, extracellular matrix-remodeling, and stress response genes, consistent with the activation of pathways involved in wound healing and tissue regeneration [1] .


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL ( 578.01 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3120 mL 11.5602 mL 23.1203 mL
5 mM 0.4624 mL 2.3120 mL 4.6241 mL
10 mM 0.2312 mL 1.1560 mL 2.3120 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: 2.08 mg/mL (4.81 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: 2.08 mg/mL (4.81 mM); Suspended solution; Need ultrasonic

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.81 mM); Clear solution

* All of the co-solvents are available by MCE.